Apartment vacation rentals in Cape Girardeau County

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Popular amenities for Cape Girardeau County apartment rentals

Weekly apartment rentals

Guest favorite
A private deck is highlighted, featuring a round glass table surrounded by six black metal chairs. The scenic view includes the Mississippi River and a colorful sunset, with the silhouette of the Emerson bridge visible in the background.
Apartment in Cape Girardeau
4.95 out of 5 average rating, 42 reviews

Downtown Condo on the River

GrahamRating, 5 stars3 months ago
Michael's place in Cape G is a perfect place to stay while you visit. It's a block from the main drag with plenty of food and bars (check out the record lounge around the corner). There's a garage space, and the balcony on the top floor has views of the Mississippi. The apartment is clean and comfortable, it would be a good medium or long term stay if desired. The bed is comfortable, and the kitchen and bathroom are modern. We'd stay again if visiting.
Superhost
A spacious dining area is seen with a glass table surrounded by light blue chairs. A stylish chandelier hangs overhead, illuminating the space. Decor includes a large area rug and decorative elements, while bicycles are parked nearby, hinting at an outdoor adventure option.
Apartment in Cape Girardeau
4.86 out of 5 average rating, 608 reviews

Unique Design | Walk Downtown/River | .5 mile SEMO

MegRating, 5 stars6 days ago
Abbi made this location absolutely adorable. There was a lot of character in this building. We did have a slight issue getting in to the place, the lock seemed to be jammed but she was responsive and immediately on it, and we were able to get in. The inside was adorable. The beds were very comfortable. I love that she had waters and some snacks available at no charge. We did take the bikes out for a ride down to the river and ate at the Marq. Everything was easily accessible. We would definitely stay again if we pass through Cape Girardeau.
Superhost
The open-concept living area showcases an exposed brick wall, enhancing the character of the space. Natural light fills the room through large windows. A comfortable sofa is positioned near a sleek coffee table, with a wall-mounted TV visible. A kitchen equipped with modern appliances is in the background.
Apartment in Cape Girardeau
4.83 out of 5 average rating, 6 reviews

2Bdrm Stay in Downtown Cape | Walkable, Laundry

MalloryRating, 5 stars4 weeks ago
We came to Cape for a quick getaway weekend from STL. Lindsey’s place was perfect for the 2 of us. Kitchen was well stocked with cooking gear but we did not use them! Beds were super comfortable!! My only real complaint is how loud the noise from the street is. Might have just been situational as I heard from many people that the college kids were all having their last hurrah but there were many many cars revving engines and squealing tires right outside the building until about 2AM. Lindsey was a fab host and we will book with her again if we ever come back to Cape!
Top guest favorite
A spacious living area features large windows allowing natural light to fill the space. A comfortable grey sofa is paired with a unique coffee table, while stylish dining chairs surround a white table. The kitchen area includes modern appliances and cabinetry.
Apartment in Cape Girardeau
4.95 out of 5 average rating, 245 reviews

Brand new 2 bedroom unit right in downtown Cape.

PabloRating, 5 stars6 days ago
Ben has a great place centered in downtown Cape Girardeau and walking distance to restaurants and breweries and the Mississippi River. Not far from SEMO campus. I recommend Ben’s place! Thanks Ben.
Top guest favorite
A spacious roof deck is highlighted, featuring a wooden surface and metal railing. Two woven chairs and a small table are positioned to allow for relaxing moments while enjoying expansive views of the river and surrounding greenery.
Apartment in Cape Girardeau
4.97 out of 5 average rating, 146 reviews

Downtown Penthouse w/ Amazing River View!

HannahRating, 5 stars5 days ago
We were all very happy with our stay! Everything was clean and tidy. We walked downtown to eat dinner, see the Mississippi River up close, and stopped for ice cream. Everyone slept so well! I would definitely stay here again!
Guest favorite
A modern living area features a sectional sofa and a recliner, providing comfortable seating. Light fixtures illuminate the space, and a ceiling fan enhances air circulation. A partition separates the entertainment area, which includes two televisions and decorative elements, contributing to a cozy atmosphere.
Apartment in Cape Girardeau
4.96 out of 5 average rating, 139 reviews

Private Downtown Apartment

SamanthaRating, 5 stars1 week ago
Cute little studio apartment right in the middle of town.
Superhost
A cozy living area features a brown leather sofa and a green armchair, accompanied by two wooden side tables. A round coffee table sits at the center, adorned with a tray and a small plant. The floor is covered by a patterned area rug, and a piece of wall art adds color.
Apartment in Jackson
4.5 out of 5 average rating, 4 reviews

Brand new apartment. Very clean!

PetroRating, 5 stars4 months ago
This is a very cozy place. Are you traveling or here for work? Erin is always available if needed. Thank you for a wonderful stay.
Top guest favorite
A view from the front porch showcases a vibrant autumn scene, with trees covered in golden leaves. A cozy seating area is visible, framed by white railings, and a peaceful street with fallen leaves creates a calm atmosphere.
Apartment in Cape Girardeau
4.98 out of 5 average rating, 414 reviews

Beautiful Historic Boulevard District Apartment

AidanRating, 5 stars4 weeks ago
Had a wonderful time at Frank and Gail’s place! Met a buddy I haven’t seen in a while and we had a great time. Plenty of space, great amenities, and good location. The owners were very friendly, checked on us when there was a big storm and made sure we had power and everything else we needed!

Private apartment rentals

Guest favorite
A private deck is highlighted, featuring a round glass table surrounded by six black metal chairs. The scenic view includes the Mississippi River and a colorful sunset, with the silhouette of the Emerson bridge visible in the background.
Apartment in Cape Girardeau
4.95 out of 5 average rating, 42 reviews

Downtown Condo on the River

GrahamRating, 5 stars3 months ago
Michael's place in Cape G is a perfect place to stay while you visit. It's a block from the main drag with plenty of food and bars (check out the record lounge around the corner). There's a garage space, and the balcony on the top floor has views of the Mississippi. The apartment is clean and comfortable, it would be a good medium or long term stay if desired. The bed is comfortable, and the kitchen and bathroom are modern. We'd stay again if visiting.
Superhost
A spacious dining area is seen with a glass table surrounded by light blue chairs. A stylish chandelier hangs overhead, illuminating the space. Decor includes a large area rug and decorative elements, while bicycles are parked nearby, hinting at an outdoor adventure option.
Apartment in Cape Girardeau
4.86 out of 5 average rating, 608 reviews

Unique Design | Walk Downtown/River | .5 mile SEMO

MegRating, 5 stars6 days ago
Abbi made this location absolutely adorable. There was a lot of character in this building. We did have a slight issue getting in to the place, the lock seemed to be jammed but she was responsive and immediately on it, and we were able to get in. The inside was adorable. The beds were very comfortable. I love that she had waters and some snacks available at no charge. We did take the bikes out for a ride down to the river and ate at the Marq. Everything was easily accessible. We would definitely stay again if we pass through Cape Girardeau.
Superhost
The open-concept living area showcases an exposed brick wall, enhancing the character of the space. Natural light fills the room through large windows. A comfortable sofa is positioned near a sleek coffee table, with a wall-mounted TV visible. A kitchen equipped with modern appliances is in the background.
Apartment in Cape Girardeau
4.83 out of 5 average rating, 6 reviews

2Bdrm Stay in Downtown Cape | Walkable, Laundry

MalloryRating, 5 stars4 weeks ago
We came to Cape for a quick getaway weekend from STL. Lindsey’s place was perfect for the 2 of us. Kitchen was well stocked with cooking gear but we did not use them! Beds were super comfortable!! My only real complaint is how loud the noise from the street is. Might have just been situational as I heard from many people that the college kids were all having their last hurrah but there were many many cars revving engines and squealing tires right outside the building until about 2AM. Lindsey was a fab host and we will book with her again if we ever come back to Cape!
Top guest favorite
A spacious living area features large windows allowing natural light to fill the space. A comfortable grey sofa is paired with a unique coffee table, while stylish dining chairs surround a white table. The kitchen area includes modern appliances and cabinetry.
Apartment in Cape Girardeau
4.95 out of 5 average rating, 245 reviews

Brand new 2 bedroom unit right in downtown Cape.

PabloRating, 5 stars6 days ago
Ben has a great place centered in downtown Cape Girardeau and walking distance to restaurants and breweries and the Mississippi River. Not far from SEMO campus. I recommend Ben’s place! Thanks Ben.
Top guest favorite
A spacious roof deck is highlighted, featuring a wooden surface and metal railing. Two woven chairs and a small table are positioned to allow for relaxing moments while enjoying expansive views of the river and surrounding greenery.
Apartment in Cape Girardeau
4.97 out of 5 average rating, 146 reviews

Downtown Penthouse w/ Amazing River View!

HannahRating, 5 stars5 days ago
We were all very happy with our stay! Everything was clean and tidy. We walked downtown to eat dinner, see the Mississippi River up close, and stopped for ice cream. Everyone slept so well! I would definitely stay here again!
Guest favorite
A modern living area features a sectional sofa and a recliner, providing comfortable seating. Light fixtures illuminate the space, and a ceiling fan enhances air circulation. A partition separates the entertainment area, which includes two televisions and decorative elements, contributing to a cozy atmosphere.
Apartment in Cape Girardeau
4.96 out of 5 average rating, 139 reviews

Private Downtown Apartment

SamanthaRating, 5 stars1 week ago
Cute little studio apartment right in the middle of town.
Superhost
A cozy living area features a brown leather sofa and a green armchair, accompanied by two wooden side tables. A round coffee table sits at the center, adorned with a tray and a small plant. The floor is covered by a patterned area rug, and a piece of wall art adds color.
Apartment in Jackson
4.5 out of 5 average rating, 4 reviews

Brand new apartment. Very clean!

PetroRating, 5 stars4 months ago
This is a very cozy place. Are you traveling or here for work? Erin is always available if needed. Thank you for a wonderful stay.
Top guest favorite
A view from the front porch showcases a vibrant autumn scene, with trees covered in golden leaves. A cozy seating area is visible, framed by white railings, and a peaceful street with fallen leaves creates a calm atmosphere.
Apartment in Cape Girardeau
4.98 out of 5 average rating, 414 reviews

Beautiful Historic Boulevard District Apartment

AidanRating, 5 stars4 weeks ago
Had a wonderful time at Frank and Gail’s place! Met a buddy I haven’t seen in a while and we had a great time. Plenty of space, great amenities, and good location. The owners were very friendly, checked on us when there was a big storm and made sure we had power and everything else we needed!

Destinations to explore