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Vacation home rentals in Appalachian Mountains

Find and book unique vacation home rentals on Airbnb

Top-rated vacation home rentals in Appalachian Mountains

Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A cozy living area features a dark gray sectional sofa adorned with bright yellow and patterned throw pillows. A wooden coffee table sits in front, complemented by a sleek remote. The space is brightened by soft overhead lighting and tasteful wall decor.
Vacation home in Arlington
4.98 out of 5 average rating, 161 reviews

1 BDRM Beaut-5 min walk to Metro/10 min from DC

Whether you are traveling for work or pleasure, look no further than this centrally located 1-bedroom/1-bath apartment, just minutes and perfectly located from DC's museums, monuments, & more! This metro accessible, luxuriously decorated apartment can accommodate your every need while in our beautiful city. Travel with ease & take advantage of a fully equipped kitchen, fast WIFI and during downtime, step outside to enjoy a relaxing evening in the shared space under the gazebo with a fire pit!

Top guest favorite
The cabin's exterior is surrounded by lush greenery, featuring a spacious porch with seating and a hot tub nearby. The two-story structure is constructed of wood, with large windows allowing natural light to fill the interior. A picnic table is located in the yard.
Vacation home in Lovingston
4.96 out of 5 average rating, 230 reviews

Ultimate cabin in the mountains

This unique and secluded cabin sits on 75 acres in the Blue Ridge mountains. Enjoy the cozy wood fireplace, hot tub, charcoal grill, and fast, reliable fiberoptic internet if you need to get some work done while you're away. It has a washer and dryer, a full kitchen, and is pet-friendly (no pet fee!), so you can enjoy it with the whole family. There is a 4K 55” smart TV with apps, a Tesla LVL 2 charger, a cabinet full of board games, books, and plenty of items to entertain both kids and adults!

Top guest favorite
A spacious living area features a high vaulted wood ceiling and large windows that allow for abundant natural light and scenic views of Cayuga Lake. Comfortable seating arrangements include a gray sectional couch and a distinctive orange chair. A patterned area rug is placed on the warm wooden floor.
Vacation home in Seneca Falls
4.98 out of 5 average rating, 132 reviews

Brand new luxury lakefront home on Cayuga Lake!

Newly built luxury accommodations on Cayuga Lake in the heart of the FLX. 4 BR (5 Beds). 3 full baths. Laundry. Wifi. Central Air. 75" Smart TV. High-end finishes. Nearby amenities include: Cayuga Wine Trail Cayuga Lake State Park Women's Rights National Historic Park del Lago Casino & Resort Waterloo Premium Shopping Outlets Taughannock Falls State Park Ithaca (Cornell University & Ithaca College) Watkins Glen State Park Family built, owned, and managed since 2022. Be our guest!

Top guest favorite
A sleek, modern outdoor area features a table lightly dusted with snow, surrounded by illuminated string lights. The glass walls provide views of a snow-covered landscape with trees and a flowing river, creating a serene winter atmosphere.
Vacation home in Shandaken
4.97 out of 5 average rating, 218 reviews

Unique BellEayre River retreat

#2024-STR-AO-85 As seen in Chronogram magazine Chronogram/docs/chronogram-april-2023 High ceilings, Rough cut beams, All new HVAC and Hearthstone soapstone wood burning stove. Take it easy at this tranquil getaway while you see and hear only the water flow with wrap around 4 season river right off deck. Close to scenic hiking, skiing, river tubing, and great restaurants along "Rapid Water"- The Algonquin Nation word for "Shandaken". Dogs welcome (Up to 2), sorry no cats.

Guest favorite
A serene view of Cayuga Lake is visible through large sliding glass doors. A spacious deck with a dining area and grill is accessible, surrounded by trees. Natural light brightens the room, highlighting the warmth of the wooden floor.
Vacation home in Ithaca
4.92 out of 5 average rating, 204 reviews

Modern Cayuga Lake House in Ithaca Kayak Fireplace

Clean, quiet, well-maintained , modern, comfortable house directly on Cayuga Lake but only minutes from downtown Ithaca, Finger Lakes wineries, Cornell, Ithaca College and gorge hikes. Our house has spectacular lake views, a modern floor plan and beautiful construction and details. New gas fireplace added in 2025. Pet Friendly, Kayaks, Canoe provided. There is an easy path with stairs from the lower parking to the house. See pictures of the steps to the lake.

Top guest favorite
The spacious master bedroom features a king-sized bed dressed in soft linens, complemented by a comfortable bench at the foot. A ceiling fan provides airflow, while natural light filters through a large window. A barn door leads to a well-organized custom closet.
Vacation home in Cincinnati
4.99 out of 5 average rating, 247 reviews

Charming 2BR/2BA with King Suite & Coffee Bar

Tastefully & thoughtfully renovated single family home is ready to welcome you to the Queen City! Brimming with exceptional touches like a lavish Coffee Bar, and expansive King suite and pillow bar, this home will leave you royally relaxed. Modern tech touches like keyless entry, free WIFI, TV Streaming Service from Youtube Premium (with access to your personal Netflix, Hulu or Disney Plus accounts) & Nest Thermostat ensure a comfortable stay.

Top guest favorite
A modern house nestles among snow-draped trees on a hillside. The structure features a prominent deck supported by stilts, framed by the serene winter landscape. Snow blankets the ground, and the scene is enhanced by the blue tones of the house contrasting with the white snow.
Vacation home in Parksville
4.93 out of 5 average rating, 187 reviews

Dreamy Catskills mountain getaway w/ yoga studio

This stunning house has been recently renovated and offers total privacy and serenity - sitting on 5 acres at the end of a quiet road. The Mountain Terrace has an indoor wood stove, a deck with a beautiful view, a fire-pit, 3 bedrooms and 2 bathrooms. There is a washer/dryer, a dishwasher an artist cabin and a private yoga studio. An easy 15 min drive to Livingston Manor for great restaurants, shopping and activities. Pet friendly.

Top guest favorite
A modern cabin is nestled among trees, featuring a sleek design with large windows that allow light to emanate from within. The surrounding rocky terrain is softly illuminated by exterior lighting, creating a calm ambiance in the early evening fog.
Vacation home in Front Royal
4.99 out of 5 average rating, 389 reviews

Mountaintop Retreat with Wood Fired Hot Tub

Doah House is a private retreat perched on a bluff atop the Blue Ridge, with wide views over the Shenandoah Valley. A calm container for rest and observation, the pace softens, shaped by small rituals: lighting the fire, soaking in the wood-fired tub, making coffee by hand. Weather moves through the trees, changing the light, the air, the sound. Each day feels different. The forest shifts, and you might, too.

Top guest favorite
A gathering area is set with bright red chairs arranged around a fire pit, with a stack of firewood nearby. The backdrop features lush greenery and distant mountains under a partly cloudy sky, reflecting the natural beauty of the surroundings.
Vacation home in Woburn
4.98 out of 5 average rating, 246 reviews

Le Malamut CITQ # 305452

Panoramic view of Mont Gosford, the highest peak in southern Quebec. Fully equipped cottage. Features 2 bedrooms with a king size bed and a queen size bed. Fiber optic!Lovers of outdoors and great outdoors will have a dream stay under a perfectly starry sky. Walking trails directly on site. We are also 20 minutes from Mont Mégantic and Lac-Mégantic. You won't be disappointed!

Top guest favorite
A charming exterior view of a recently renovated home is captured at night. Soft light illuminates the entrance and windows, while snow gently covers the surrounding area. The welcoming porch features wooden railings and steps leading to the front door, framed by trees in the background.
Vacation home in Niagara Falls
4.97 out of 5 average rating, 116 reviews

Gorgeous Gem in Niagara’s Wine Country

A newly renovated, well appointed artistic home. Centrally located near the Falls, Niagara Parkway, Niagara-on-the-Lake, casinos, wineries and the largest outlet mall in Canada. (A car is recommended since the closest public transportation is 2 km away.) A great gathering spot in any season with a full kitchen, laundry and outdoor space ready to entertain family and friends.

Guest favorite
An indoor pool area features a long, narrow pool, surrounded by large windows that allow natural light to fill the space. The tiled floor is complemented by potted plants, and wicker chairs with cushions are arranged nearby for seating.
Vacation home in Evansville
4.94 out of 5 average rating, 191 reviews

Nugent House

It's rare to find a place that's both historic and one-of-a-kind. Whole house to enjoy in downtown Evansville Indiana. Walking distance to arts district , bars , restaurants, casino , ford center , Evansville museum, Evansville riverfront and much more.,, Home was built in 1915 as a mansion by the Nugent family. No lifeguard on duty, swim at your own risk

Guest favorite
The exterior of the A-frame retreat features a dark gray facade and triangular architecture. Soft lighting outlines the roof. A small entrance leads to a glass window, revealing hints of the interior. A bistro set with two chairs is placed outside, offering a view of the landscape.
Vacation home in Lincoln
4.88 out of 5 average rating, 165 reviews

Cozy A-Frame Retreat in Niagara Wine Country

Escape to our restored 1950s A-frame tucked among sweeping vineyard and Escarpment views. With 3 bedrooms, 2 baths, and a fully renovated kitchen, it’s made for slow mornings with coffee, relaxed evenings by the fireplace, and days exploring world-class wineries and nearby trails. A peaceful, central retreat perfect for couples, families, and friends.

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