
Guesthouse vacation rentals in Appalachian Mountains
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Appalachian Mountains
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Appalachian Mountains guesthouse rentals
Family-friendly guest house rentals

Peaceful weekend or extended stay, full amenities
I had a great experience with Matt & Laura. They did a great job communicating and their property is very nice!

On the Vineyard @ 1068, Niagara on the Lake
Lisa and Amanda checked in with us prior to and when we arrived. We were pleasantly surprised by lovely bottle of wine and chocolates in the kitchen. Lisa made some wonderful suggestions for the area. The house exceeded our expectations. Lisa checked in with us to ensure all was acceptable on day 2 as well and made herself available to us if we needed anything. We had a significant snowfall and they ensured that the snow was cleared and access was safe. I look forward to enjoying another visit in their home. It is exceptionally clean, well maintained and stocked with everything that we could possibly need. Comfortable beds and bedding. Thoughtful additions of cozy throw blankets, body lotion, shampoo, conditioner, body wash and blow dryers were included in both of the washrooms. Everything is as it appears in the photos. Lakeview winery is across the road and walkable and fun for tastings. Perfect location!!!

Guesthouse On 1879 Farm. Hot tub and hiking
Had a great stay here. Hosts were extremely responsive and provided local recommendations. Their property was expansive and they were very accommodating and let us explore - we had a beautiful hike through the trails, listened to birds, saw the ponds/lakes/waterfalls nearby. The bed was so comfy and everything felt clean! Fresh towels and linens were provided. TVs were easy to use. We had fun playing with the various board games! The hot tub was a huge plus and the hosts preheated it so even though it was chilly outside, the hot tub was super hot and ready for us as soon as we got to the property. Felt clean and easy to use, the cover is heavy but easy enough to slide on and off. The local town is about a 10 minute drive from the property. Not very lively but there are a few restaurants, a used book store (I bought 15 books for under 10 dollars!), the dollar general is huge and is like a mini Target, lots of stuff. Overall great stay and very affordable for a nice getaway from life

Liz Lane Cottage- entire guesthouse
Definition of southern hospitality! The cottage was both spacious and spotless. Host was incredibly responsive and made everything leading up to our stay a breeze! Cottage was so well stocked and all of our bedding was luxe and very comfortable! Less than 15 minutes from the heart of Charleston! Would not only recommend, I hope to visit again soon 😊

Wishing Well Guesthouse On The Lake
Enjoyed our visit! Susan made us delicious cookies and cinnamon rolls!

The Cock and Feather Guesthouse
This was a truly unique Airbnb experience with all of the vintage details they’ve incorporated into this well laid out and equipped guest house. We enjoyed the peaceful location and being right down the road from all of the historic Gettysburg sites.

The Guest House at Chandlery Farm
We had an amazing time staying at this lovely house. It is our third time here which shows how much we love it. The house is beautiful with so many artistic and comfortable touches - from the piano to the chairs to the bedding, everything is absolutely perfect. The location is stupendous as well - the house is located on farmland where highland cows graze. We happily spent an entire snowy day never leaving the extensive property - there are beautiful places to walk and sled right next to the house. Everything was perfect and we look forward to staying again.

*MINUTES to DOWN TOWN *MOUNTAIN VIEWS*PETS OK*
This was our second time staying at Jaclyns home. It's beautiful and peaceful, quiet and comfortable. She is a gracious hostess and you feel like your home. We will definitely will be back.
Guest house rentals with a patio

Beautiful Guest House
Brandon’s guest house was perfect and Brandon was a great host and always available….would definitely recommend to anyone staying in that area

Clean and modern 1 bedroom studio pool house.
Jane's pool house was perfect for what I needed...It was quiet and calm and cozy and in beautiful surroundings...It was very private. Jane is also a great host...she really went out of her way to make it feel like it was MY place to stay with a very warm welcome.

Bungalow on a 3 acre mini farm
Wow—what a gem of a stay! Jonathan is one of the kindest and most thoughtful hosts we’ve ever had. We loved the fresh eggs and getting to hear how he got into hosting—it really added a personal and meaningful touch to our visit. The place itself felt like a page straight out of a storybook—cozy, charming, and full of little details that made it feel magical. There was so much to do, from fun games to quiet spots to relax. The tub was incredibly relaxing—exactly what we needed after a long day of hiking. Total bliss! We’re already planning to try out the fire pit next time too. And don’t worry about going hungry—Jonathan provides so much food. You definitely won’t starve here! Thank you again, Jonathan, for such a wonderful and memorable stay. Can’t wait to come back!

Guest House/Apt, private fully equipped, sleeps 4
we had amazing peaceful time at Donna's place, they were amazing host. walked in and felt comfortable and at home. we will be back :) ps very clean

Bruce Peninsula Country Loft on 17
We had an incredible girls weekend - it was so relaxing and everything we could have ever wanted. They’ve made such an incredible getaway we’re so grateful to have been able to find - the personal touches, thoughtfulness, amazing amenities and details that have went into every aspect of the property have us already dreaming of coming back for another getaway to relax and recharge! From start to finish this stay far exceeded our expectations and we could not have asked for better hosts or a better stay!

The Violet Villa w/no cleaning fee
This home was absolutely stunning! Very cozy and great features. It is in a quiet community the is so adorable. Bed is so comfortable we wanted to take it home with us. Host is very responsive and was accommodating to an early check in. If in the area again we would definitely stay. I would recommend this home to anyone. ❤️

Incredible Guest House Sylvania
(PLEASE READ IT ALL) This is the first AirBnB me and my gf have ever stayed in, so we learned a lot from this that may be obvious to others, when we first got there we didn’t realize that we did not have the whole property to ourselves and because of that, we attempted to enter the part of the house that (I assume it was Lisa) was currently using! We got there late so we scared Lisa and it also scared us… sorry Lisa!! I’ll admit that at first I was disappointed/uncomfortable with the fact that we didn’t have the whole property and that our section was connected to the main house not by a door thankfully but by a wall and was afraid that if we even talked too loud, Lisa would be able to hear, but after getting settled, we ended up loving the set up and realized we have more privacy than initially thought! Lisa not once made her presence known and I appreciated that, there was one time when me and my gf saw her leave early morning and we jokingly waved and Lisa waved back, that was funny

Downtown guest house with private hot tub & deck
Ashlie’s place was beautiful!! It was so cute and so fun for the weekend! The place was super clean and the hot tub was an amazing place to unwind! Any time we had a question even after we arrived she was super quick to respond and super helpful!
Guest house rentals with a washer and dryer

Guesthouse w/FREE snacks & private river access
Excellent place to relax and enjoy Blue Ridge, GA. Quiet, clean and comfortable. Highly recommended!

Ray of Sunshine in Dalton
Adorable little cottage, decorated beautifully! Perfect for our little family of three, and was well stocked with any and everything you may need during your stay. Everything was very clean, and well organized. Plenty of space to set up our pack & play in the bedroom. It was a little chilly, but the host provided space heaters & extra blankets that helped! Amazing stay & highly recommend!

Lola's Retreat, near ferry to Mackinac Island
Very cozy quiet place!! Clean and had everything we needed. Felt like home and will be back!! Thank you so much!!

Quiet Guest House
Wonderful quiet clean place to stay. Convenient location. Has everything you need and more. Very responsive host. Have stayed here previously and already booked for another stay.

Cape Cottage
First time visit to Cape May for my daughter and I. We had privacy, we’re able to sleep in, see the local area and do our laundry on site. Kristie was very responsive!!!!

Carriage House on Main near NRG National Park
Amy's West Virginia Airbnb was fantastic! The spacious, clean house was well-equipped and comfortable, with a great location near many beautiful sights. Amy was an exceptional host, providing excellent communication and helpful tips. Highly recommended for a wonderful stay!

Private Guest House
Great place, easy to locate. Was close Athens! Beds were comfortable, shower were hot and nice pressure. We stayed 2 nights and it was just a place to rest my heads! We stayed inside only a few hours and that was just for sleep. It meet all our requirements and was better than expected.

Kline's Cottage
Thank you, Mallory, for the lovely stay. The house was spotless and very cozy and your thoughtful touches made us feel right at home. We appreciated your quick responses. The location is perfect as it's only a 10 minute drive to Watkins Glen State Park. Definitely would recommend.
Destinations to explore
- Rentals with a balcony Appalachian Mountains
- Rentals with an accessible height toilet Appalachian Mountains
- Rentals with a beach view Appalachian Mountains
- Yurt rentals Appalachian Mountains
- Condo rentals Appalachian Mountains
- Cottage rentals Appalachian Mountains
- Rentals with a home theater Appalachian Mountains
- Train rentals Appalachian Mountains
- Houseboat rentals Appalachian Mountains
- Rentals with a fireplace Appalachian Mountains
- Rentals with a patio Appalachian Mountains
- Tipi rentals Appalachian Mountains
- Earth house rentals Appalachian Mountains
- Hotel rentals Appalachian Mountains
- House rentals Appalachian Mountains
- Pet-friendly rentals Appalachian Mountains
- Beachfront rentals Appalachian Mountains
- Rentals with outdoor seating Appalachian Mountains
- Resort rentals Appalachian Mountains
- Shipping container rentals Appalachian Mountains
- Rentals with a kayak Appalachian Mountains
- Apartment rentals Appalachian Mountains
- Rentals with lake access Appalachian Mountains
- Villa rentals Appalachian Mountains
- Fitness-friendly rentals Appalachian Mountains
- Townhouse rentals Appalachian Mountains
- Cabin rentals Appalachian Mountains
- Rentals with an EV charger Appalachian Mountains
- Ski-in/ski-out rentals Appalachian Mountains
- Smoking-friendly rentals Appalachian Mountains
- Kid-friendly rentals Appalachian Mountains
- Rentals with a hot tub Appalachian Mountains
- Bungalow rentals Appalachian Mountains
- Aparthotel rentals Appalachian Mountains
- Nature eco lodge rentals Appalachian Mountains
- Castle rentals Appalachian Mountains
- Tiny house rentals Appalachian Mountains
- Dome rentals Appalachian Mountains
- Treehouse rentals Appalachian Mountains
- Loft rentals Appalachian Mountains
- RV rentals Appalachian Mountains
- Island rentals Appalachian Mountains
- Luxury rentals Appalachian Mountains
- Boutique hotel rentals Appalachian Mountains
- Campsite rentals Appalachian Mountains
- Boat rentals Appalachian Mountains
- Hostel rentals Appalachian Mountains
- Rentals with beach access Appalachian Mountains
- Waterfront rentals Appalachian Mountains
- Farmstay rentals Appalachian Mountains
- Rentals with a fire pit Appalachian Mountains
- Private suite rentals Appalachian Mountains
- Rentals with breakfast Appalachian Mountains
- Chalet rentals Appalachian Mountains
- Rentals with a soaking tub Appalachian Mountains
- Rentals with a sauna Appalachian Mountains
- Tent rentals Appalachian Mountains
- Rentals with an accessible height bed Appalachian Mountains
- Barn rentals Appalachian Mountains
- Rentals with pools Appalachian Mountains
- Serviced apartment rentals Appalachian Mountains
- Bed and breakfasts Appalachian Mountains
- Vacation home rentals Appalachian Mountains
- Family-friendly rentals Appalachian Mountains
- Rentals with a washer and dryer Appalachian Mountains
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Things to do Appalachian Mountains
- Art and culture Appalachian Mountains
- Wellness Appalachian Mountains
- Sports activities Appalachian Mountains
- Tours Appalachian Mountains
- Entertainment Appalachian Mountains
- Sightseeing Appalachian Mountains
- Food and drink Appalachian Mountains
- Nature and outdoors Appalachian Mountains