Guesthouse vacation rentals in Southern United States

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Southern United States

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

A canoe is positioned on still waters, surrounded by dense fog that creates a serene atmosphere. The seat is adorned with a blanket featuring a red cross design, adding a touch of color amidst the muted landscape. Tree silhouettes emerge faintly in the background.

Guesthouse in Monroe

Bayou Long Beard - Bayou view! We greet everyone!

Hi, I’m Clay and I love to meet new people and have traveled all over the world for the past 20 years working with bands. This journey, along with my new wife Joy, has lead to us becoming Airbnb hosts. Our eclectic, cozy, charming, spacious and right on the Bayou listing is a place we are sure you’ll love. Large picture windows for gazing at the bayou let in lots of natural light. Fully handicap accessible! Not suitable for children. Cleanliness and hospitality are our specialties! No pets!! 5🌟

5.0 out of 5 average rating, 353 reviews

Top guest favorite

Guesthouse in Bella Vista

Women of the Woods • Where the Forest Finds You

Step inside and feel the outside disappear. This beautifully curated woodland retreat is tucked into the trees of Bella Vista with a woodsy backyard that opens directly onto the Back 40. Guests consistently remark on attentiveness of hosts, cleanliness, and thoughtful touches. Close enough to everything when you're ready for it, Downtown Bentonville is 20 minutes away. Crystal Bridges, world-class mountain biking, scenic hiking, lakes, shopping, restaurants, and golf are all within easy reach.

5.0 out of 5 average rating, 121 reviews

Top guest favorite

The exterior of a brick guesthouse cottage is presented, featuring a pointed roof and tall, arched windows. Lush greenery surrounds the entrance, which has a wooden door framed by two lanterns. Stone steps lead up to the front door, enhancing the inviting appearance.

Guesthouse in Bentonville

Cozy Cottage on C

Welcome to our structural masonry guesthouse cottage in the heart of Downtown Bentonville. You'll feel like you're stepping back in time into a historic building made entirely out of brick, but our backyard cottage was completed in 2023 as a labor of love and hospitality. Enjoy direct access to Park Springs Park and trails at the end of the block, or a short walk/ride to the Downtown square. We live in the main house on the property, but designed the cottage to maximize guest privacy. Welcome!

4.98 out of 5 average rating, 392 reviews

Guest favorite

A spacious guest room is highlighted by a queen bed dressed in warm-toned linens. Natural light filters through large windows adorned with sheer curtains. A cozy seating area includes a sofa and a round coffee table. A decorative fireplace and small dining set add to the inviting decor.

Guesthouse in Owasso

French Woods Quarters

Our guesthouse has a very warm, peaceful decor to parallel the nature around it. You will likely see many deer and other wildlife from the huge covered back porch while enjoying a meal cooked in your full kitchen. You will also have access to an attached single-car garage where there is also a washer and dryer available for your use. The pool is left open year round. Whether you need a place to get away and relax or place to call home while you're traveling for work, this is your place!

4.88 out of 5 average rating, 318 reviews

Top guest favorite

A serene landscape is captured with tall trees casting long shadows over a lush green lawn. Sunlight filters through the branches, illuminating the space and creating a calming outdoor atmosphere.

Guesthouse in Tahlequah

Serene setting w/ private Illinois River access

Come relax with the family! This one bedroom guest house is just a stones throw from private access to the Illinois river. Located 15 minutes from Tahlequah and 10 minutes from local float venues. Come and enjoy a peaceful and quiet stay at the foothills of the Ozarks. Bring Your Own Float Devices and enjoy floating down to Todd Landing public access point, which is about an hour long adventure. Relax on the deck while enjoying the local wildlife! Bald eagles and deer frequent the area.

4.89 out of 5 average rating, 121 reviews

Top guest favorite

A spacious deck overlooks a lush green valley with rolling hills blanketed in morning fog. A circular hot tub is positioned on the deck, providing a tranquil view of the mountains in the distance. The scene is illuminated by soft sunlight.

Guesthouse in Stanton

Robbie’s Rest: Amazing Mountaintop Sunrises

2020 new unit with nice deck, wonderful mountain scape with amazing sunrises from your deck or the deck of the main house where host lives. 8 acres that sit where the rolling hills meet the mountains overlooking the Daniel Boone Forest. 35 miles from Lexington, you will enjoy the peace & quiet of the beautiful mountains. Minutes away from the trails, waterfalls & attractions of Natural Bridge State Park & the Red River Gorge! We hope you will visit us soon! *Sunrise is not always visible

4.98 out of 5 average rating, 380 reviews

Top guest favorite

A classic blue muscle car is parked in front of a grand two-story brick mansion featuring large white columns. The manicured lawn is visible in the foreground, framed by lush greenery. Stairs lead to an ornate entrance with glass doors.

Guesthouse in Covington

Lockwood Mansion Carriage house / Vampire Diaries

Welcome to Lockwood Home of one of the founding families in Mystic Falls, you'll be adding yourself to the guest list with the likes of Damon and Stefan Salvatore, Matt Donovan, Jeremy Gilbert and Tyler Lockwood! The entire property was an authentic stage set for the hit television show The Vampire Diaries for eight years. During your stay, you may enjoy touring the grounds, lake and a private tour inside the mansion. Don't miss the opportunity to stay right where the action happened!

5.0 out of 5 average rating, 202 reviews

Top guest favorite

A modern living space features a gray sectional sofa adorned with patterned throw pillows. A round coffee table sits in front, surrounded by decorative accessories. Tall windows allow natural light to fill the room, complemented by a textured area rug and a tall plant for added warmth.

Guesthouse in Rogers

The Penthouse in DTR

Enjoy a stay at the only Luxury apartment rental conveniently located just two blocks from downtown Rogers. The Penthouse in Downtown Rogers is a modern and stylish apartment with all the amenities you need for a short stay or a long retreat: sumptious Sleep Number bed and bedding, gourmet kitchen and outdoor barbecue area, luxe shower and outdoor hot tub with an outdoor fire pit to boot. Just 3 blocks from the Railyard mountain bike park, a short trail to lake Atalanta park.

4.98 out of 5 average rating, 370 reviews

Top guest favorite

A modern living room is illustrated, featuring a 50-inch Smart TV mounted on a wooden media console. Leather sofas are positioned opposite a coffee table, which is set with a coffee service. Large windows reveal views of trees and foliage, enhancing the natural ambiance.

Guesthouse in Bella Vista

Tanyard Creek | Waterfall · Bike In/Out

Walk to the waterfall. Ride to the trails. Relax in the trees. Set directly above Tanyard Creek, this private guesthouse offers immediate access to scenic hiking paths and nearby MTB trails—making it the perfect basecamp for both riders and nature-focused stays. Designed for those who want to be outside during the day and fully recharge at night, the space is dialed for comfort with Tempur-Pedic beds and a specialty coffee setup to start your mornings right.

4.94 out of 5 average rating, 156 reviews

Guest favorite

Guesthouse in Dallas

Casita - Willow House Guest House

This unique place has a style all its own. Close to Bishop Arts and Downtown our guest house has all the privacy and convenience you need. Thru your private entrance you walk past the waterfall pond, under an arch of tree vines, into a cozy and updated home. Outside at the end of the wraparound porch you’ll find a private fire pit. On the rooftop there’s a 2 person hot tub with incredible views of the city and Dallas National Golf Club.

4.88 out of 5 average rating, 178 reviews

Top guest favorite

Guesthouse in Fort Worth

Lake Retreat/Fire Pits/Dock/Games/Stockyards 11 Mi

Escape to a cozy lake retreat on peaceful Eagle Mountain Lake, just 25–30 minutes from the Fort Worth Stockyards. Spend the evening around the fire pit (with complimentary s’mores September through April), play games inside, fish from the dock, relax on the dock swings to enjoy your morning coffee by the lake. This is the perfect base location for exploring the many great activities that Fort Worth has to offer.

4.99 out of 5 average rating, 138 reviews

Guest favorite

A charming cottage features a distinctive tower and is painted in light blue with dark blue trim. The entrance, adorned with a seasonal wreath, is flanked by a small seating area. A stone pathway leads to the steps, providing access to the welcoming porch.

Guesthouse in Lone Jack

Adorable cottage on Beautiful property w/ hot tub

Take it easy at this unique and tranquil getaway. Enjoy your own private cottage with all the essentials for a comfortable stay. The cozy space is just under 200 sq ft and features a queen-size bed plus a loft mattress. Guests may enjoy exclusive access to the hot tub (lower level of main house) and a 1-acre pond stocked with catfish, and bluegill.

4.9 out of 5 average rating, 363 reviews