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Vacation rentals in Santa María

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa María

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A scenic view of rolling hills under a colorful sky at sunset. Shades of orange, pink, and purple blend, creating a vibrant horizon. Lush trees are scattered across the landscape, adding a touch of greenery to the terrain.
Cottage in Olá
4.95 out of 5 average rating, 21 reviews

Casa de Campo en Olá, ríos, cascadas, Los Picachos

Finca La Terapia hace honor a su nombre, se encuentra entre las montañas del pintoresco pueblo de Olá de Penonomé, en la cual podrás desconectarte del ajetreado día a día de la ciudad. Cuenta con 42 Hectáreas privadas para explorar la naturaleza. El distrito de Olá, se caracteriza por tener lo mas hermosos paisajes Naturales entre los que podemos mencionar, Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, entre otros a muy poco minutos de la Finca.

Top guest favorite
An aerial view showcases a serene saltwater pool framed by lush greenery. Red umbrellas provide shade for outdoor seating areas. The open kitchen and dining space are visible, along with comfortable hammocks situated nearby, offering a relaxed atmosphere for guests.
Home in Costa Esmeralda
4.98 out of 5 average rating, 190 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Superhost
A hammock is suspended under a covered terrace, overlooking a serene beach. Yellow chairs are positioned nearby on a wooden deck, complemented by a coastal view featuring calm blue waters and a clear sky. The scene is tranquil and inviting for relaxation.
Chalet in Juan Hombron
5 out of 5 average rating, 4 reviews

Casa con encanto acceso a playa

Relájate con toda la familia en este alojamiento donde la tranquilidad se respira. Casa Candelaria te invita a disfrutar de una maravillosa estadía, con contacto directo a la naturaleza. Desde el jardín de la casa, accedes a la playa, una playa bella!!, sin pendiente, de arena cálida y sobre todo, no concurrida! Si te gusta las caminatas en la playa con la luz del amanecer, este sitio es ideal, además... podrás compartir con tu familia, barbacoas mirando al mar!!! CASA CANDELARIA, ENJOY!!!!

Guest favorite
A vibrant red house is depicted alongside a thatched-roof gazebo, surrounded by lush green grass. Outdoor dining furniture is visible, providing a space for relaxation. The open sky brightens the scene, enhancing the sense of openness and connection with nature.
Farm stay in Rio Grande
5 out of 5 average rating, 7 reviews

Escape to Nature at cabañita de Kaïs !

Welcome to la Cabañita de Kaïs, Eco Farm Stay in Coclé. Located just 10 minutes from the Panamericana in the beautiful province of Coclé, Finca Nora is a peaceful eco-farm where you can enjoy a true countryside experience. Surrounded by nature, our farm offers direct access to friendly animals like goats, cows, and chickens, making it a perfect escape for families and nature lovers alike. Disconnect, breathe, and connect with authentic rural life is easy at this unique and peaceful getaway.

Guest favorite
A single-story house is nestled beneath a large tree, featuring a tiled roof and a covered parking area. Surrounding greenery includes bushes and ornamental plants, enhancing the natural setting. The house is positioned to provide a sense of privacy and tranquility.
Home in Chitre
4.87 out of 5 average rating, 62 reviews

Country House Like in the City / La Casita

Casa fresca, con árboles y naturaleza. Áreas amplias para descansar. Ubicación céntrica, cerca de malls, restaurantes, estación de buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Ahora, Chitré, tiene un problema con el agua: no está potable; tenemos 50% de lo habitual, a veces estamos sin agua por algunas horas. Por favor, consulten antes de reserar.

Guest favorite
A refreshing swimming pool sits in the foreground, complementing the rustic building behind it. Lush greenery and potted plants surround the area, enhancing the natural setting. A shaded patio area with outdoor seating is visible, offering a serene environment for relaxation.
Guesthouse in La Enea
4.96 out of 5 average rating, 49 reviews

Casa de Campo con Piscina en La Enea de Guararé

Lejos de la urbe capitalina, ven a disfrutar del folklore panameño en un espacio rústico pero acogedor viviendo una experiencia autóctona. Relájate en la piscina ó descansa en una hamaca, respira aire puro, cerca del mar, rodeado de jardines amplios y naturales para un buen paseo. Cerca del Puerto de Guararé donde disfrutarás de los mejores mariscos y bebidas ó disfruta el corazón del mejor evento del folklore resaltando las tradiciones y las mejores polleras panameñas.

Superhost
Farm stay in Santa Fe
4.89 out of 5 average rating, 302 reviews

Cabaña del Sol en Finca Namuiki by the River

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

Guest favorite
Cottage in Santa Fe
5 out of 5 average rating, 6 reviews

k* Casa Matilde | 2BR Santa Fe Retreat by River

Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

Top guest favorite
A comfortable porch area features two colorful hammocks suspended from the walls. The polished tile flooring reflects soft light, and a pair of large wooden doors stands closed in the background. A vehicle is parked nearby, adding to the casual ambiance.
Home in Penonome
4.92 out of 5 average rating, 129 reviews

Casa cómoda, cercada y segura.

En Casa las Hamacas, disfruta de la sencillez de este alojamiento espacioso, tranquilo y céntrico. Podrás disfrutar del agradable clima penonomeño. Un lugar cerca de todo, centros comerciales, escuelas, hospital, montaña ríos y playas. Ambas habitaciones cuentan con aire acondicionado para garantizar tu descanso. A pocos minutos de la vía interamericana.

Guest favorite
The two-story colonial house is showcased with a white facade and wooden accents. Decorative balconies with railings are present at the front, along with several potted plants adding color. The street is lined with other buildings, under a clear blue sky dotted with clouds.
Cottage in Parita District
4.8 out of 5 average rating, 44 reviews

Colonial House in Parita

Discover the charm of Parita from a comfortable and spacious home, perfect for large groups. Located in the picturesque and peaceful town of Parita, in the Herrera Province, just 12 minutes from Chitré, this spacious home is the ideal place to immerse yourself in the history and culture of a historic colonial-era town.

Guest favorite
A bright bedroom is displayed, featuring a spacious bed covered with a textured white blanket. A television is mounted on the wall opposite the bed. Natural light floods through large windows, accompanied by sheer curtains. A cozy orange chair and potted plant add a touch of warmth.
Tiny home in Playa El Jobo
4.94 out of 5 average rating, 18 reviews

Little home near to the beach -Las Tablas

10 min drive- Las Tablas Get away from it all when you stay under the stars. A room very close to the sea, with an open kitchen that will allow you to disconnect and enjoy the view and nature in Las Tablas. You can plan to visit nearby beaches or take a walk through Pedasí, 30 minutes from Las Tablas.

Top guest favorite
A cozy sleeping area features a wooden bed with a decorative headboard, dressed in a white quilt. Soft morning light filters in, illuminating the textured wall behind. A small side table, harmonizing with the room's wood accents, complements the overall design.
Apartment in Llano Marín
5 out of 5 average rating, 9 reviews

Aparta Luxe

Disfruta de la mejor experiencia de hospedaje céntrico en Penonomé, en un departamento con finos acabados de madera, doble balcón, situado idealmente para darte privacidad, tranquilidad, disfrutar de lindos atardeceres y que también te brinda un espacio para trabajar.

Popular amenities for Santa María vacation rentals

  1. Airbnb
  2. Panama
  3. Herrera
  4. Santa María