Vacation rentals in Santa María District

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Top-rated vacation rentals in Santa María District

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Guest favorite

Cabin in Torio

4.97 out of 5 average rating, 101 reviews

Cozy open space, unique jungle views, river access

Casa Corotu is located in Torio Hills a 10 minute's walk to the beach with a a trail to access Torio river. Fiber Optic WiFi and two work spaces. The property surrounded by big trees that keep the house cool, which also provide shelter for birds and wildlife. The house is NOT childproof, minimal railing system. It's a great house to live the experience of #toriolife and all it has to offer. It is also an opportunity to experience the jungle in an open-style home with a mesmerizing treetop view.

Mar 7 – 14

ﺩ.ﺇ438 per night

Guest favorite

Villa in Playa Venao

5.0 out of 5 average rating, 22 reviews

Villa Verde - Luxury&Cozy Villa 1BR #26 BlueVenao

Relax & Calm in a cozy villa with an amazing view of the mountains, located in Playa Venao Beach The villa is fully equipped with 1 Queen size bed and a Sofa bed, High Speed Wi-Fi, Netflix, kitchen cooking tools and appliances like stove, oven, dishwasher, microwave, coffee maker, toaster and blender. Also, you will find a complete laundry with washer and dryer, towels for use inside the Villa, as well as for the pool & beach. Bedrooms come with complete bedding clothes/linens and pillows

Jul 4 – 11

ﺩ.ﺇ612 per night

Guest favorite

Guesthouse in Torio

4.91 out of 5 average rating, 111 reviews

Torio guesthouse with panoramic view

Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.

Aug 21 – 28

ﺩ.ﺇ290 per night

Guest favorite

Home in Pedasí

4.94 out of 5 average rating, 117 reviews

3 min to Pedasi, 5 min to the Beach, Private Pool!

Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

Nov 19 – 26

ﺩ.ﺇ644 per night

Guest favorite

Home in Costa Esmeralda

4.96 out of 5 average rating, 106 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sand! Come relax with the whole family at this piece of paradise. Majestic Sand is located in a private beach community in Costa Esmeralda, San Carlos District, Panama. It is located a few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, Santa Clara and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool with multiple hammocks with views of amazing palm trees.

Dec 19 – 26

ﺩ.ﺇ760 per night

Superhost

Earthen home in El Cope, Penonome

4.91 out of 5 average rating, 147 reviews

Beautiful Eco House in Panama

We are very pleased to offer our beautiful, modern, comfortable house designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and escape daily stress. It is in a beautiful part of Panama near a cloud forest national park. The house sits in 17 acres of forest and has 2 rivers for swimming. The house is very open allowing full enjoyment of nature. There are amazing hiking opportunities in the mountains with waterfalls and visits to local communities.

Apr 10 – 17

ﺩ.ﺇ796 per night

Guest favorite

Apartment in Los Canelos

5.0 out of 5 average rating, 12 reviews

Salamanca Loft

Este hermoso apartamento esta ubicado en el centro de todo Panamá en la hermosa provincia de Herrera, vía interamericana, a pocos minutos de varias ciudades como Chitré, Aguadulce y Santiago. En un ambiente tranquilo, rodeado de árboles. Si corren con suerte podrán observar desde lejos las hermosas iguanas que se pasean por las ramas mas altas. Pueden apreciar al caer la tarde una hermosa puesta del sol. Justo al frente, hay cafetería, también hay pizzerías a domicilio y restaurantes.

Jul 12 – 19

ﺩ.ﺇ135 per night

Guest favorite

Home in Taboga Island

4.96 out of 5 average rating, 141 reviews

Casa Rosie - Taboga dream home

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Jul 28 – Aug 4

ﺩ.ﺇ890 per night

Superhost

Home in Playa Venao

4.9 out of 5 average rating, 115 reviews

Beautiful Home Directly on Playa Venao Sleeps 8-10

This is our personal home and we take good care to make sure you thoroughly enjoy your stay! This home is located on the best surfing beach in the entire country. Walk out of your back door onto the sandy beach filled with wildlife and the best beach break for beginners to pros. This home offers luxury accommodations. This home is for families and respectful renters only. We do not accept groups who want to use the home to party.

Mar 14 – 21

ﺩ.ﺇ2,377 per night

Guest favorite

Home in Santa Catalina

5.0 out of 5 average rating, 25 reviews

Casa Colibrí - modern house in the green

Casa Colibri is a beatiful, spacious home in the middle of nature and will make your stay in Santa Catalina perfect. It has a large terrace with a fantastic view into the green where you can relax and listen to the birds. The interior has a lot of natural light and stays cool during the day, in case you need to escape the tropical heat. It is the perfect place for a unique experience in this special town with your friends or family.

Jul 7 – 14

ﺩ.ﺇ528 per night

Guest favorite

Home in Playa Mata Oscura

4.92 out of 5 average rating, 25 reviews

Casa De Ola, Jungle Beach Cabin

Welcome to Paradise: Your Pacific Jungle Oasis Nestled deep within the lush, untamed heart of Panama's wild Pacific coast, this remote jungle cabin isn't just a place to stay—it's an invitation to experience life at its most primal and extraordinary. It is a destination by itself. This is your passport to a world where nature reigns supreme, adventure lurks around every emerald-green corner, and artistry dances with the elements.

Jan 13 – 20

ﺩ.ﺇ688 per night

Superhost

Home in Vista Mar Golf, Beach & Marina

4.88 out of 5 average rating, 224 reviews

Luxurious Beach House - Private Pool Golf & Marina

Vista Mar Golf, Beach & Marina is a gated community with private security, with direct access to a state of the art golf course designed by J. Michael Poellot. It also has marina, heliport, tennis courts, direct private beach access, bars and restaurants. The house comes with an outdoor private pool & hot tub, also a amazing private outdoor kitchen, and an amazing sea view with spectacular sunrises and sunsets.

Jan 11 – 18

ﺩ.ﺇ2,854 per night