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Vacation rentals in Santa María

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Top-rated vacation rentals in Santa María

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A serene landscape features geodesic domes nestled among lush greenery, set against a backdrop of rolling hills. The sky displays soft hues as the sun sets, creating a peaceful atmosphere. A pathway winds through the area, leading to additional structures in the distance.
Dome in El Valle de Antón
4.76 out of 5 average rating, 117 reviews

5 min from Valle I Domo No. 6-Free coffee

🌄 Dome in El Valle – Nature, peace and incredible views • 🆕 New dome, queen size bed • 🚿 Private en-suite bathroom • 🌬️ Cool mountain climate all year round • 🌿 Surrounded by vegetation • 🌄 Breathtaking views • 🐶 1 small pet • ❄️ Fridge, microwave, and coffee maker (no kitchen) • ☕ Welcome courtesy: Small amounts of coffee, sugar, and cream for use at the start of your stay. • 🚗 5 minutes before El Valle (the last two minutes are a gravel road; small cars can pass) • 🕒 3:00 pm | 🕛 12:00 noon

Top guest favorite
A small, rustic structure is positioned amidst a lush, mountainous landscape. A winding gravel road leads towards the building, surrounded by greenery, hills, and trees. The scene is softly illuminated by sunlight, highlighting the natural setting and open space.
Shipping container in San Carlos
4.98 out of 5 average rating, 61 reviews

Justinatinyhouse disconnects to connect

Justinatinyhouse is nestled in the foothills of the San Carlos Lagoon. It has everything you need for your stay with a lot of peace, a cool breeze in the mornings and afternoons, incredible views towards Altos del María, Sorá, Punta Chame, and a dirt road in good condition for any car. It has A/C and everything you need for your stay. It does not have a TV, but there is excellent cell phone coverage. I recommend bringing all the things you need for your food. The nearest store is a 10-minute drive away

Top guest favorite
The living area features large glass doors that invite natural light and views of the garden. Indoor plants enhance the space, and a cozy seating arrangement includes a sofa and eclectic chairs. A workspace with a desk and lamp is positioned to the side.
Guesthouse in El Valle de Antón
4.99 out of 5 average rating, 116 reviews

Spacious Casita with Bamboo View

Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Guest favorite
An aerial view captures a charming retreat nestled in lush greenery. The red-tiled roof of the cabin stands prominently surrounded by colorful gardens and fruit trees. A winding path leads to the property, with a vehicle parked nearby, highlighting the spacious natural surroundings.
Tiny home in Cocle
4.93 out of 5 average rating, 136 reviews

Cozy 2 Bedrooms, el Cope/ Retreat at the Mountains

Hermosa cabaña de dos habitaciones y dos baños , den panorámico ubicada a unos 50 minutos de Penonome, Provincia de Cocle, en el Area del Parque Nacional Omar Torrijos Herrera , temperaturas entre 22 y 25 grados C a orillas del turístico Chorro de las Yayas en la comunidad de Barrigon del Cope, distrito de La Pintada. Agradable ambiente rodeado de árboles frutales y hermosas cascadas. Ideal para disfrutar de la naturaleza y relajarse. Cuenta con internet satelital de rápida velocidad .

Guest favorite
Cabin in Altos del Maria
5 out of 5 average rating, 7 reviews

Deimos – Modern Mountain Cabin with Jacuzzi

Deimos is a one-bedroom cabin featuring a fully equipped kitchen, a modern bathroom, and a living room that opens onto a private terrace with a jacuzzi. The property consists of a total of three houses, and Deimos is located at the highest point, slightly farther from the others, offering added privacy. The tiny home comes fully equipped with everything needed for a weekend getaway or a longer stay, making it the perfect place to relax and enjoy the amenities of Altos del María.

Top guest favorite
The exterior of the cabin is showcased amidst lush greenery, featuring a sloped roof and large glass windows. A wooden staircase leads up to the entrance, while a stone pathway meanders through the garden, enhancing the natural surroundings.
Cabin in Penonome
4.98 out of 5 average rating, 128 reviews

Aqeel cabin in the nature

Relax at this unique and tranquil getaway surrounded by nature. If you're lucky, you may wake up to see white-faced capuchins from your bedroom window and spot an abundance of birds, such as the crested oropendola or a toucan. The property offers river access with a sandy, beach-like area, and there is a 1 km walking trail alongside the river. With satellite high-speed internet access, you'll stay connected, though the river and sandy area may not be accessible during rainy days.

Guest favorite
A small pool sits within a wooden deck area, surrounded by lush greenery. Steps lead from the deck to the pool, where a gentle waterfall feature adds a soothing element. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Guesthouse in Panamá Oeste
4.83 out of 5 average rating, 134 reviews

Mountain cabin with private pool

Enjoy peace and nature in this cozy and equipped cabin, perfect for disconnecting and relaxing. Surrounded by forests and spectacular views, here you can breathe fresh air and gaze at the stars. ✔️ Ideal for couples, families or adventurers. ✔️ Trails, rivers and viewpoints nearby. ✔️ Comfortable and equipped spaces for your comfort. - Sleeps 4 people. - Possibility of having 1 double bed and 2 single beds or 4 single beds. - Discount for two nights or more.

Guest favorite
A spacious outdoor deck features modern furniture arranged for relaxation, overlooking a lush mountainous landscape. Verdant hills and a colorful sky at dawn create a tranquil environment, inviting guests to enjoy the natural beauty and serenity of the surroundings.
Villa in El Copé
4.92 out of 5 average rating, 188 reviews

Mountain retreat

Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Guest favorite
Cabin in Altos del Maria
4.83 out of 5 average rating, 127 reviews

Cabin in Altos del María

Cozy cabin in Altos del María, ideal for couples looking to relax in a mountain setting. Enjoy a cold climate, surrounded by nature. It is pet-friendly and is equipped with the essential amenities: a room with a queen-size bed, sofa bed, and inflatable mattress, perfect for up to 4 people. It has a washing machine, grill, hammocks and guard post for added security. The atmosphere is conditioned to blend in with nature. Parking for 3 cars.

Superhost
A geodesic dome is nestled among lush greenery, surrounded by tall trees. The structure features a wooden deck that extends into the natural landscape, providing a seamless connection with the environment. Mist shrouds the distant hills, enhancing the tranquil setting.
Dome in Altos del Maria
4.93 out of 5 average rating, 100 reviews

Los Domos Panama, Domo Fuego, Glamping en Altura.

Immerse yourself in a natural oasis where the connection with nature becomes palpable. Surrounded by trees and coffee plantations, our space offers a unique experience for those looking to reconnect with nature. From the birdsong to the pure air you breathe, every moment here is an invitation to harmony. We have a private river of totally fresh spring water and immerse yourself in the night experience with our outdoor hot tub.

Top guest favorite
Camper/RV in El Valle de Antón
4.99 out of 5 average rating, 254 reviews

Armadillo Shelter & Garden Valle de Anton

It is a unique and special accommodation that we have designed for you to experience the Anton Valley in a more conscious and natural way. It's a remodeled RV or trailer, to make it cozy>functional and comfortable>tiny house style. The space has a small and complete kitchen, hot water, Wi-Fi, coffee and tea. It is surrounded by a nice garden. With a separate entrance and an area to park the car. Ideal for 1-2 people.

Guest favorite
Farm stay in Santa Fe
4.9 out of 5 average rating, 313 reviews

Sun Cabin at Finca Namuiki by the River

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

Popular amenities for Santa María vacation rentals

  1. Airbnb
  2. Panama
  3. Herrera
  4. Santa María