Guesthouse vacation rentals in Saint Johns River

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Saint Johns River guesthouse rentals

Family-friendly guest house rentals

Guest favorite
Guesthouse in Port Orange
4.87 out of 5 average rating, 202 reviews

Chic & Cozy Modern Pool Home

BrennaRating, 5 stars2 weeks ago
Dariya was very responsive to any and all needs / questions. The pool house was spotless and quite comfortable. I suggest adding more lamps to the living area space, but overall it was great!
Top guest favorite
Guesthouse in St. Petersburg
4.89 out of 5 average rating, 323 reviews

Carriage House in North St. Pete

TomRating, 5 stars3 weeks ago
Extremely friendly, gracious, and thoughtful host. Have stayed with before and will again.
Guest favorite
Guesthouse in Tampa
4.93 out of 5 average rating, 110 reviews

Adorable South Tampa Two-Story Guest House

JoanRating, 5 stars3 weeks ago
While the location of this home is in the midst of the city and near the airport, the neighborhood was quiet and walkable, stores and restaurants were nearby and there was easy access to highways. It was a comfortable place to return" home: to each day. The beds and couch were comfortable and the air conditioners really helped. James and his family were very friendly and helpful. The size of the unit was fine for two people, but with a small bathroom and kitchen, might be a challenge for 3.
Guest favorite
Guesthouse in Orange Park
4.91 out of 5 average rating, 164 reviews

Graceful Southern Guesthouse + Outdoor Living Area

HollyRating, 5 stars4 days ago
We stayed in Orange Park for our daughter’s wedding weekend and it was absolutely perfect!
Guest favorite
Guesthouse in Tampa
4.85 out of 5 average rating, 338 reviews

Hyde Park Tree House, Tampa, FL - Great location

HeatherRating, 5 stars2 weeks ago
Peaceful treehouse in the heart of Hyde Park. The location is great, bed very comfortable and we enjoyed the screened porch .
Top guest favorite
Guesthouse in Windermere
4.94 out of 5 average rating, 266 reviews

Paradise nook near Orlando's theme parks

Jessica CatherineRating, 5 stars2 weeks ago
We had a wonderful stay at Noga’s place on Hemple Ave! The home was exactly as described—clean, stylish, and incredibly comfortable. The location was perfect: quiet and peaceful, yet just a short drive from everything Orlando has to offer. Noga was a gracious and responsive host, making sure we had everything we needed throughout our stay. From the thoughtful touches to the easy check-in process, every detail was taken care of. We would absolutely stay here again and highly recommend it to anyone looking for a relaxing and well-appointed Airbnb in the area.
Guest favorite
Guesthouse in Fort McCoy
4.88 out of 5 average rating, 281 reviews

Blueberry Farm Country Cottage

RebeccaRating, 5 stars1 month ago
We had a wonderful stay with Walt and Cassandra. The house is very nice. The furniture and decor are very personalized and absolutely harmonious with the whole location The kitchen was excellently equipped - almost the best Airbnb we have ever had during all our travels. It was very easy to cook dinner. Another positive thing to mention is the bed - we slept very well on the mattress. About the area: The house is quiet and you can easily relax away from the hustle and bustle of a city. Super starry sky due to the low light pollution. There are chickens on the property, which provided us with fresh eggs every morning. There are also 2 cats living on the property. We can absolutely recommend the accommodation and would book it a second time.
Guest favorite
Guesthouse in Vero Beach
4.92 out of 5 average rating, 155 reviews

Country Life Guest house with pool

JenRating, 5 stars1 month ago
Peaceful, comfortable place with friendly hosts and animals; many places for walks, bike rides, and rollerblading (wish I'd brought mine); close drive to stores, restaurants and attractions; definitely would stay again; the cats were our favorites

Guest house rentals with a patio

Top guest favorite
Guesthouse in Sebastian
4.92 out of 5 average rating, 133 reviews

Quiet cottage on Sebastian River property

KaylaRating, 5 stars1 week ago
Very beautiful place , very quiet and peaceful but still very convenient to shopping and restaurant's the best part was the dock on the water I enjoyed coffee on the dock with the dolphins every morning 🌄 will book with him again
Guest favorite
Guesthouse in Tampa
4.88 out of 5 average rating, 152 reviews

Luxury guesthouse, 1 mile from Hard Rock Casino

HunterRating, 5 stars4 days ago
Couldn’t say enough good things about this place. This place was clean, easy to find and right in a perfect spot of Tampa. If you in the area. This is the place to stay.
Top guest favorite
Guesthouse in Tampa
4.97 out of 5 average rating, 132 reviews

Cute Guesthouse by the Riverwalk, w/patio and WFH

LuisRating, 5 stars1 week ago
Hello! The stay here was great! I'd absolutely love to come and stay again for a longer period if possible. It felt so cozy, it was clean , the garden in the back made it feel peaceful. Thank so much for the space Dawn, my wife loved it!
Guest favorite
Guesthouse in Inverness
4.88 out of 5 average rating, 105 reviews

Tranquil guest home with beautiful salt water pool

RobinRating, 5 stars6 days ago
We absolutely had the best time. The Salt water Pool was amazing..... Such a great time. We met Erica, Jack her son and Soka their yellow Lab. Omg what a super nice family. Restaurant's are super slose. We did not want to leave. The Sun shines from 8amto 7pm. Amazing for laying out.. Cant say enough great things. We will be a regular here!!!
Top guest favorite
Guesthouse in Tampa
4.99 out of 5 average rating, 155 reviews

Quiet and clean guest house!

LouisRating, 5 stars3 weeks ago
We simply loved this place! We felt at home we really had a great time! The host is extremely responsive and kind. Highly recommend
Guest favorite
Guesthouse in Tampa
4.96 out of 5 average rating, 289 reviews

Tiny House Oasis Blue Vatican . Near MacDill Base

SabrinaRating, 5 starstoday
Excellent and responsive. Beautiful place
Superhost
Guesthouse in Tampa
4.83 out of 5 average rating, 185 reviews

Adorable 1 Bedroom Ybor Casita with outdoor patio

ChiRating, 5 stars2 weeks ago
A great place to stay for our short visit to Tampa! Close walk to Ybor area for great restaurants and bakery shops! Short drive to downtown Tampa. The apartment is clean and has everything we need. The hosts are very responsive to questions throughout our stay. High recommend!
Guest favorite
Guesthouse in Orange Park
4.93 out of 5 average rating, 190 reviews

Mom's Little House - self check-in

JimberlyRating, 5 stars2 weeks ago
Vicki’s place was awesome! Quiet neighborhood, close to restaurants, grocery stores, etc. Her place is very clean and had everything we needed. We would definitely stay again.

Guest house rentals with a washer and dryer

Top guest favorite
Guesthouse in Dunedin
4.95 out of 5 average rating, 165 reviews

Tiki Hut Cottage

RachelRating, 5 stars5 months ago
The Tiki Hut was beautiful. The lush outdoor area made for an amazing view and experience. The house was mostly clean, the carpets seemed a bit dirty but we still felt comfortable and at home. Wonderful hosts! We would rent again.
Superhost
Guesthouse in Riverview
4.82 out of 5 average rating, 121 reviews

The Casita-Adorable guest house!

JoseRating, 5 stars2 months ago
I think the location was perfect, plus I always felt at home. The host was always attentive and responded on time. The place is quiet, beautiful, and surrounded by good neighbors. Walmart, Publix, and other places to eat were nearby. Great place, I highly recommend it 100%.
Top guest favorite
Guesthouse in Orlando
4.93 out of 5 average rating, 103 reviews

Kyle's Place - Private Unit, Pool + Laundry Room

KaylaRating, 5 stars6 days ago
Place was a peaceful stay, area was quiet which i loved ! Place was clean loved my stay here and would highly recommend to anyone :)
Guest favorite
Guesthouse in Fort White
4.98 out of 5 average rating, 121 reviews

Adorable cozy cabin near North Florida Springs

GaryRating, 5 stars3 weeks ago
We enjoyed the stay at Lisa’s. It was peaceful and quiet. Anything needed was there and if not she would help out in anyway she could. Needed something fixed, which never happened, her husband was an excellent service person. Lol. I’m saying this because he is my wife’s cousin and we surprised them an rented the cabin without them realizing it was us. I might b a little partial in writing this but truly if you want to relax and get away from all the rushing around then this is the place to be. Thank you Lisa and Randy for a great time. Can’t wait til next time. The river is beautiful.
Guest favorite
Guesthouse in Jacksonville
4.91 out of 5 average rating, 240 reviews

Large 1 bedroom Cottage with full kitchen

EssenceRating, 5 stars1 week ago
I absolutely loved this space! I felt right at home. The neighborhood was super quiet and peaceful. I felt safe as a young solo traveler. The house was spacious and worth every penny! The house comes stocked with pretty much everything you need for a stay! Cameron is very friendly and responsive. definitely a gem!
Superhost
Guesthouse in Orlando
4.92 out of 5 average rating, 257 reviews

Modern Guest Studio (Private) Pool / Spa available

BrandiRating, 5 stars1 week ago
Had a great stay, communication was great. We had a small hiccup with the hot tub and problem was solved very quickly. The only thing I would complain about and not really complaining is there were cloths and a used towel hanging on the back of the bathroom door. No biggie and honest mistake by cleaners other then that the stay was amazing and felt like home away from home. Will stay again for sure
Top guest favorite
Guesthouse in St. Petersburg
4.98 out of 5 average rating, 114 reviews

2 bedroom guesthouse in hip Grand Central District

DaleRating, 5 stars1 week ago
Tidy, well managed space! We appreciated the thoughtful attention to detail, particularly the available coffee and toiletries. Made our visit easy and enjoyable. Be aware of some street noise from nearby busy road and freeway, particularly evident in the bedroom with queen bed. Overall, a nice place with easy access to all St Pete amenities!
Top guest favorite
Guesthouse in Lady Lake
5 out of 5 average rating, 138 reviews

Cute & Cozy Tiny Guesthouse

RhondaRating, 5 stars1 week ago
I cannot say enough kind things about staying with John and Ruthie! Such an easy self check in and a peaceful, private entrance suite. They have really put a lot of thought into the space. They left us a snack basket with crackers, granola bars, and chocolates. Several types of sodas, water in the fridge. Great little Keurig coffee bar with lots of different types of K-cups, even hot chocolate. And cold creamers in the fridge! Great little kitchenette if you want to cook something. Publix grocery store is right down the street. Bed was very comfortable with nice linens. Everything was so well organized and spotlessly clean. Nice fluffy towels and specialty soaps in the bathroom. I really can’t even think of a single thing that could be added. Neighborhood was very quiet and safe. It was perfect and we will definitely be back!

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