
House vacation rentals in Saint Helena Island
Find and book unique houses on Airbnb
Top-rated house rentals in Saint Helena Island
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Saint Helena Island house rentals
House rentals with a pool

The '56 Retreat

Lovely 3BR in Palmetto Dunes w/ new pool & spa

Piece of heaven

Cozy Coastal Chic - Beach, Pickleball, Golf, Pets

Located mid-island by tennis courts, marsh sunsets

Resort-Style Pool, Cute House 88 Steps to Sand

W2Bch*4TVs*1GIG I*PetsWC *WiFi*4King ßds*grill*gms

Peaceful Harbour Town Treehouse with Marsh Views
Weekly house rentals

Salty Roots

Cottage near beach & mil. bases

Fall at Fripp! Views, Pet friendly, Golf Cart

Beautiful 3-bedroom home close to the beach.

Secluded LowCountry Retreat. Boaters welcome!

The Market Croft

Whispering Palms Cottage

Grace Cottage - Your Home Away From Home!
Private house rentals

One Particular Harbor

Bungalow in Historic Downtown Beaufort!

Peaceful, Lowcountry Artist Retreat

Serenity Shore Retreat-Vet-Owned-Minutes from PI

Marsh views with dock, pool, & elevator!

Downtown Beaufort’s Cozy Jackson Cottage🌴

Beautiful views on Fripp Inlet!

Comforts of Home/WD/1G Wi-Fi/Pet OK
Destinations to explore
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- Coligny Beach Park
- Park Circle
- Forsyth Park
- Hunting Island State Park Beach
- Sullivan's Island Beach
- North Beach, Tybee Island
- Harbour Town Golf Links
- Palmetto Dunes Oceanfront Resort
- Middleton Place
- The Westin Savannah Harbor Golf Resort & Spa
- Shipyard Beach Access
- James Island County Park
- Waterfront Park
- The Golf Club at Wescott Plantation
- Shem Creek Park
- Tybee Beach Pier and Pavilion
- Bradley Beach
- Angel Oak Tree
- Mid Beach
- Hampton Park
- Harbor Island Beach
- Dolphin Head Golf Club
- Secession Golf Club
- The Charleston Museum