Vacation rentals in San Luis Obispo County

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Top-rated vacation rentals in San Luis Obispo County

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Top guest favorite
A wooden gate with a decorative wreath opens into a welcoming path surrounded by lush greenery and vibrant flowers. The cottage's exterior is partially visible, providing a glimpse of a charming entrance and well-maintained landscaping.
Apartment in San Luis Obispo
5 out of 5 average rating, 135 reviews

Very Spacious Edna Valley Luxury Apartment

The Nottage is a welcoming cottage-like apt. located in the heart of the Edna Valley. Luxury and style afford you upgraded comfort in a beautiful garden setting. At approx. 1000 sq. ft. and no shared walls, you will enjoy quiet living with plenty of space for longer stays. Central but peaceful - Pismo & Avila Beaches, and downtown SLO, are 10-15 mins. away. Guests have full access to the Pickle and Bocce ball courts on the property. We are only minutes away from multiple well-known wineries.

Top guest favorite
A charming garden area is framed by brick pathways, with a wooden table and chairs positioned nearby. Lush greenery and various plants create a serene outdoor atmosphere, while a wooden gate provides privacy and access to the space. The ground appears damp, suggesting recent rain.
Guesthouse in San Luis Obispo
4.97 out of 5 average rating, 629 reviews

SLO Guesthouse - quiet - near downtown - #115545

Private studio with it's own entrance located in lovely SLO. Includes a queen size Murphy bed (people rave about the comfort of this bed), 3 piece bathroom, table & two chairs, desk, closet, TV, WiFi & kitchenette. Coffee, tea with fixings are provided. 4 blocks from the downtown cultural-hub, hip restaurants, Farmer's Market, the Historic Mission and more. The Edna Valley wine country is 5 minutes away and the Beach is 10 minutes away. The Perfect Location to come experience the "SLO Life"!

Top guest favorite
A charming entrance to the cabin is illuminated by large, lit letters spelling 'CABIN.' The pathway is lined with stone, leading through lush greenery toward the cozy structure, which features a blue roof and warm outdoor lighting, creating a welcoming ambiance.
Cabin in Santa Margarita
4.97 out of 5 average rating, 181 reviews

The Cabin at Whisper Valley Ranch

Welcome to Whisper Valley Ranch! A unique cabin stay on 160 acres of caves, creeks, and hiking trails in the heart of San Luis Obispo County. Exquisitely designed & comfortably furnished, this getaway will provide the tranquil escape you need. Immerse in the ultimate central coast experience with personalized activities that can be planned onsite. Jam making, horseback riding, wine tasting, private chef meals...all can be yours in the comfort of the Cabin. Follow us on IG: whispervalleyranch

Top guest favorite
The exterior of the remodeled farmhouse is depicted, showcasing a red façade with white trim. A welcoming porch is furnished with two chairs, and a stone pathway leads to the entrance. Lush greenery and rolling hills surround the property under a clear blue sky.
Farm stay in San Luis Obispo
4.98 out of 5 average rating, 219 reviews

HISTORIC FARM HOUSE ON 400 ACRE RANCH

Come experience something unique and magical in our turn-of-the-century remodeled farm house. This rustic home lies within a 400 acre ranch located just over the mountain from the City of SLO. Allow yourself to travel back in time while you enjoy this 2 bedroom, 1 bath 1000' home which comfortably sleeps 4 guests in its king and queen beds. The newly remodeled kitchen with its granite counters and modern appliances is fully equipped. Relax outside on the flagstone patio or wrap-around porch.

Top guest favorite
A newly built 1-bedroom home is set against a backdrop of rolling green hills. The structure features a modern design with a dark exterior and a covered porch area. A small dog sits on the concrete driveway, adding a welcoming touch to the scene.
Home in San Luis Obispo
4.99 out of 5 average rating, 128 reviews

Hilltop Horizon: Centrally Located+Panoramic Views

Newly built,secluded 600 sq ft 1 bedroom home with panoramic views of all of San Luis Obispo. Home is centrally located at 7min from both downtown &/or wineries, 3 miles to Cal Poly- but is completely quiet with no traffic on our multi acre property. This home shares the driveway and parking with our family’s main house, but the home has been designed for the two sets of 8ft glass sliders to have unobstructed views while maintaining complete privacy. We are 15 minutes to Avila and Pismo Beach.

Top guest favorite
An expansive view of a serene olive grove is presented, showcasing numerous olive trees nestled among lush green grass. The landscape is framed by trees, under a clear blue sky adorned with scattered clouds, creating a peaceful outdoor setting.
Cottage in San Luis Obispo
4.95 out of 5 average rating, 453 reviews

Peaceful Cottage in an Olive Grove

Come relax in this cozy cottage removed from the frantic world but so close you can easily go back at any time. Whether you choose to unwind in the serenity that surrounds our olive farm or venture out to experience all that SLO County has to offer, you'll be in the perfect spot for either or both. We're on a road less traveled with neighbors few and far between but located just 10 minutes from wine tasting, beaches, downtown SLO, the Village of Arroyo Grande, hiking trails and so much more.

Top guest favorite
A spacious bedroom is equipped with a large bed draped in a decorative quilt, complemented by colorful pillows. Two bedside tables with lamps are placed beside the bed. A small dining table and chair set sits by a window, allowing natural light to illuminate the room.
Apartment in San Luis Obispo
4.97 out of 5 average rating, 371 reviews

Mountain View Studio - No Cleaning Fee!

Your home away from home is close to Cal Poly, hiking, art and culture, great views, restaurants, wineries, and several beaches. This spacious studio apartment has a super-comfy bed and is located in a quiet neighborhood with easy access to all things SLO. We use only natural, organic cleaning products, and all sheets and towels are of high-quality cotton. Kitchenette stocked with coffee, tea, etc. Smart TV. Licensed in the city of SLO ( #113984), so a required 13% lodging tax is included.

Top guest favorite
A modern kitchen features vibrant blue cabinetry contrasting with light walls and natural accents. A sleek stove and stainless-steel appliances are present alongside a small wooden dining table and chair. Large windows allow ample natural light, complemented by greenery from potted plants.
Home in San Luis Obispo
5 out of 5 average rating, 196 reviews

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT

Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Unwind next to the fire pit in the backyard. It's a short 7 min. stroll to downtown & next to 5 restaurants including Sally Lou's coffee shop & the train station. Experience SLO's charm like never before with this perfect location home. Send us a message to plan your trip!

Top guest favorite
A dining table is set with four place settings, featuring white plates, brown napkins, and glassware. A bottle of red wine stands centered on the table, while the kitchen is visible in the background, showcasing modern appliances and light-colored cabinetry.
Home in Atascadero
4.99 out of 5 average rating, 118 reviews

Z Ranch-Modern Country Luxury with Stunning Views

Welcome to Z Ranch! Spotless, private 1br/1.5ba offers effortless self check-in and French country elegance—pure California charm. Perfect for a wine country escape, just 1 min to downtown Atascadero, 15 min to SLO, Paso Robles, or Morro Bay. Relax on the private balcony with sweeping views, where deer often wander just feet away. Enjoy a full kitchen, wine fridge, AC, washer/dryer, smart TV, memory foam queen bed. Please Note: We do not allow guests to bring pets OF ANY TYPE.

Top guest favorite
Barn in Atascadero
5 out of 5 average rating, 202 reviews

The Barn at Old Morro

The Barn at Old Morro is a refreshing and beautiful space centrally located to all the Central Coast has to offer! Tastefully appointed and well stocked, the barn is the perfect getaway for Paso Robles wine country, the Cayucos/Cambria/Morro Bay Coast, San Luis Obispo shopping or exploring the gorgeous Big Sur coastline! Set in a beautiful spot at the lower end of our property under a mature and majestic grove of oak trees with overhead twinkling bistro lights.

Guest favorite
The exterior of the home is framed by vibrant red foliage, with a mix of trees and shrubs surrounding a well-maintained lawn. Large windows provide views into the interior, while a wooden deck extends outward, complementing the natural landscape.
Home in San Luis Obispo
4.86 out of 5 average rating, 117 reviews

Serenity On Serrano

Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

Top guest favorite
A dining area features a wooden table surrounded by four chairs, complemented by a decorative rug. Exposed beams and ductwork enhance the industrial style. Natural light fills the space through large glass walls, revealing the adjacent kitchen and bedroom area.
Home in San Luis Obispo
4.98 out of 5 average rating, 271 reviews

Mid Century Modern Loft Downtown SLO

This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

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