Vacation rentals in San Luis Obispo County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in San Luis Obispo County

Guests agree: these stays are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Guesthouse in San Luis Obispo

4.97 out of 5 average rating, 472 reviews

SLO Guesthouse - quiet - near downtown - #115545

Private studio with it's own entrance located in lovely SLO. Includes a queen size Murphy bed (people rave about the comfort of this bed), 3 piece bathroom, table & two chairs, desk, closet, TV, WiFi & kitchenette. Coffee, tea with fixings are provided. 4 blocks from the downtown cultural-hub, hip restaurants, Farmer's Market, the Historic Mission and more. The Edna Valley wine country is 5 minutes away and the Beach is 10 minutes away. The Perfect Location to come experience the "SLO Life"!

Oct 6 – 13

ﺩ.ﺇ398 per night

Guest favorite

Apartment in San Luis Obispo

4.96 out of 5 average rating, 282 reviews

Mountain View Studio - No Cleaning Fee!

Your home away from home is close to Cal Poly, hiking, art and culture, great views, restaurants, wineries, and several beaches. This spacious studio apartment has a super-comfy bed and is located in a quiet neighborhood with easy access to all things SLO. We use only natural, organic cleaning products, and all sheets and towels are of high-quality cotton. Kitchenette stocked with coffee, tea, etc. We are licensed with the city of SLO (license #113984), so a required 13% lodging tax is included.

Aug 14 – 21

ﺩ.ﺇ499 per night

Guest favorite

Apartment in Arroyo Grande

4.92 out of 5 average rating, 405 reviews

Central Coast Living

New two bedroom apartment Home with a full kitchen, living room, and patio. This clean / modern apartment is based in a semi-rural neighborhood located right off historic Hwy 1. Located slightly on the OUTSKIRTS for a more peaceful stay, this home is only a 10 minute drive from the beach, Central Arroyo Grande, the Oceano Dunes, wineries, hiking and biking trails, and farmers markets. 15 minutes from Pismo Beach and 20 minutes from San Luis Obispo. 5 minutes from 2 golf courses. PETS WELCOME.

May 13 – 20

ﺩ.ﺇ396 per night

Guest favorite

Guest suite in Arroyo Grande

4.99 out of 5 average rating, 306 reviews

Bright Nature Oasis by the Historic Village!

Nestled in a tree filled oasis on .75 acres, just a 5 minute walk from the historical Village of Arroyo Grande. Our property is the perfect get away from the bustle of life and into nature without being too far away from everything the central coast has to offer. Our bright, cheery, one bedroom guest quarters is the perfect place to rest while you enjoy all of the great things to do on the central coast. Minutes from shopping, restaurants, wine tasting, beautiful beaches and hiking trails.

Dec 11 – 18

ﺩ.ﺇ461 per night

Guest favorite

Guest suite in San Luis Obispo

4.93 out of 5 average rating, 1086 reviews

Mid-Century Design Close to Downtown & Cal Poly

Mid-Century-Design Homestay's private addition offers a tranquil space to explore San Luis Obispo and Central Coast. We thoroughly clean and sanitize plus HEPA air purifier - 24/7. Two separate bedrooms. Fine Art and white walls with large windows that lead out to a private shaded deck w/firepit table for 6. License #113141. It has heat/AC, kitchenette, Pvt. bathroom off of the main bedroom, washer/dryer, Pvt. entrance, free parking, with or without a friendly Lab. View at slostay, with .com.

Mar 25 – Apr 1

ﺩ.ﺇ523 per night

Guest favorite

Cottage in San Luis Obispo

4.96 out of 5 average rating, 329 reviews

Peaceful Cottage in an Olive Grove

Come relax in this cozy cottage removed from the frantic world but so close you can easily go back at any time. Whether you choose to unwind in the serenity that surrounds our olive farm or venture out to experience all that SLO County has to offer, you'll be in the perfect spot for either or both. We're on a road less traveled with neighbors few and far between but located just 10 minutes from wine tasting, beaches, downtown SLO, the Village of Arroyo Grande, hiking trails and so much more.

Sep 25 – Oct 2

ﺩ.ﺇ609 per night

Superhost

Guest suite in Arroyo Grande

4.93 out of 5 average rating, 177 reviews

Secluded wine country retreat, full kitchen

This spacious secluded guest suite in the heart of California's Central Coast wine country is on a quiet three-acre gated property. Surrounded by ancient oaks, springtime wildflowers and songbirds, your Retreat has everything you'd possibly need: private entrance, full kitchen, double shower, laundry, fireplace, giant flat-screen TV, Wi-Fi, private patio, covered carport, air conditioning, and a bottle of wine from a local winemaker. Minutes from vineyards, golf, restaurants and beaches.

Mar 10 – 17

ﺩ.ﺇ409 per night

Guest favorite

Guesthouse in Arroyo Grande

4.94 out of 5 average rating, 509 reviews

Private, serene studio near beach & wineries

Our private country setting offers you a tranquil spot to unwind and discover the beauty of the Central Coast. Ideally located on a quiet country street, you are a short drive from (under 10 minutes) dipping your toes in the ocean at Pismo Beach, sipping award-winning wine at one of the dozens of nearby Edna Valley wineries or getting a bite to eat at many of the casual or finer dining restaurants. When you arrive, our dog and our other pets large and small will give you a warm welcome!

Oct 12 – 19

ﺩ.ﺇ462 per night

Guest favorite

Guesthouse in San Luis Obispo

4.92 out of 5 average rating, 289 reviews

The tree house

Peaceful, bright and airy 450 sq foot unit. Just over a mile from downtown and 2.1 miles from Cal Poly. The unit is totally separate and set away from the main house with a private entrance and private outdoor seating area. Enjoy a restful sleep in a king sized bed with down comforter and pillows and Italian cotton sheets. Stylish bathroom with large shower and vanity. Separate living room/kitchenette area with coffee & tea making facilities, a breakfast bar and bar seating.

Oct 2 – 9

ﺩ.ﺇ545 per night

Guest favorite

Bungalow in San Luis Obispo

4.96 out of 5 average rating, 436 reviews

Montgomery Vineyard

Montgomery Vineyard was once part of the oldest dairy farm in San Luis Obispo County. The unique accommodations offers guests an eclectic décor of antiques and memorabilia from behind the camera in Hollywood. The views from the large, private deck are of the vineyard and the vineyard covered hills beyond. It is a lovely, relaxing place to enjoy a complimentary bottle of wine made from the grapes grown in Montgomery Vineyard. Beautiful Avila Beach is just down the road.

May 24 – 31

ﺩ.ﺇ633 per night

Guest favorite

Guesthouse in San Luis Obispo

4.92 out of 5 average rating, 120 reviews

SLO Casita, a short walk to everything!

Visit our sweet casita at the foot of Cerro San Luis mountain in San Luis Obispo! This cozy little spot is around the corner from an incredible deli, a short walk to a beautiful hike, and a 15 -20 minute walk to downtown. This is an ideal spot for a couple looking to soak up the best San Luis has to offer or a group of up to three to stay in the perfect location.

Aug 29 – Sep 5

ﺩ.ﺇ418 per night

Guest favorite

Guest suite in San Luis Obispo

4.91 out of 5 average rating, 297 reviews

Harris House

A private studio space right in downtown San Luis Obispo. Located in an updated 1935 home, the private entrance leads you upstairs to your own room complete with bathroom, reading nook, and kitchenette area with a microwave, electric kettle, mini refrigerator, and pour over coffee. This is a great launching pad for exploring all around San Luis Obispo.

Oct 6 – 13

ﺩ.ﺇ366 per night