Vacation rentals in Panama Canal

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Top-rated vacation rentals in Panama Canal

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

A modern living room is showcased with large floor-to-ceiling windows offering city views. A neutral-toned sofa, accented with colorful pillows, is positioned alongside two round tables on a textured area rug. Artwork adorns the walls, and a dining area can be seen in the background.

Apartment in Panamá

4.89 out of 5 average rating, 18 reviews

Luxury apt in Panama City 2 Rooms 3 Baths & office

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Guest favorite

The balcony features a round wooden table set with a glass candle holder, surrounded by wicker chairs. A panoramic view of the water and city skyline extends in the background, while colorful market lights add a subtle charm along the railing.

Apartment in Panama City

4.94 out of 5 average rating, 32 reviews

The Captain's Canal View Penthouse

Experience luxury & stunning views in the Captain's Canal View Penthouse, owned by a Panama Canal Pilot & designed for ship-watching. This one-of-a-kind apartment offers panoramic vistas of Panama Bay's cityscape on one side and the bustling canal on the other. Located on the Amador Causeway, you're steps from vibrant restaurants, bars, & the cruise ship terminal. Your stay includes exclusive access to StandUp Panama, where you can paddle at sunrise on the canal for an unforgettable experience.

Guest favorite

A modern living area features a plush area rug underneath a glass coffee table, which displays decorative items and books. A flat-screen TV is mounted on a marble accent wall, and elegant dining furniture is visible in the background, creating a sophisticated and inviting atmosphere.

Apartment in Panamá

4.93 out of 5 average rating, 30 reviews

Apartamento con calor de hogar Yoo & Arts Panamá

Vive la experiencia de un apartamento con un ambiente de calor de hogar, elegante y moderno Ubicado en la exclusiva Avenida Balboa de Ciudad de Panamá en el reconocido edificio icónico Yoo Panamá & Arts Tower. Situado en una de las zonas más prestigiosas, estarás rodeado de lo mejor: restaurantes de renombre, centros comerciales y la zona histórica más emblemática. Disfruta del confort y estilo que solo Yoo Panamá & Arts Tower puede ofrecerte. Haz de tu estancia una experiencia inolvidable.

Top guest favorite

Apartment in Panamá

5 out of 5 average rating, 7 reviews

Acogedor apartamento frente al mar.

Este lugar es único, tiene su propio estilo. Su ubicación es estratégica, será muy fácil llegar. Se encuentra ubicado junto a la Cinta Costera, cerca de la estación del metro, Casco Antiguo, y todos los centros turísticos que Panamá te brinda. Ven y disfruta de esta hermosa experiencia en uno de los mejores edificios de Panamá, el cual te ofrece tranquilidad, entretenimiento, gastronomía, coctelería, historia de Panamá, vistas impresionantes, todo esto dentro del mismo Edificio. ¡Visítanos!

Superhost

Apartment in Panamá

4.75 out of 5 average rating, 8 reviews

Casco Viejo / Penthouse w/ Terrace & Views

Nuestro Penthouse, en el último piso de La Cuadra Residence, en Casco Antiguo, cuenta con terraza privada con vista al Océano Pacifico y su entrada al Canal de Panamá, Cerro Ancón, Casco Antiguo, Cinta Costera, Biomuseo, Puerto de Cruceros de Amador y el skyline de la hermosa Ciudad de Panamá. Contamos con acceso privado al área social y piscina, desde nuestra terraza. Nuestro Lobby cuenta con acceso privado al restaurante Ayala Vida, de autentica comida panameña y Duran Coffee Store.

Top guest favorite

A modern living area is furnished with a dark sectional sofa adorned with colorful cushions. A coffee table rests on a patterned rug, and large windows provide a view of the ocean, allowing natural light to fill the space.

Apartment in Panamá

4.93 out of 5 average rating, 58 reviews

Elegancia y Confort con Vista Panorámica al Mar

Vive la experiencia del lujoso PH Yoo frente al mar en este elegante apartamento con cama king y ventanales de piso a techo. Disfruta de amenidades de primer nivel: piscina, gimnasio, squash, spa y más. Ubicación privilegiada, cerca de zonas turísticas, restaurantes, bares y centros comerciales. Dentro del edificio encontrarás opciones gastronómicas con descuentos exclusivos y valet parking gratuito. Un espacio moderno, amplio y sofisticado, ideal para una escapada inolvidable.

Guest favorite

A modern living area features a large wave mural that enhances the space's vibrant decor. Comfortable seating arrangements include a sleek white sofa and a pair of stylish armchairs. A glass coffee table is centered among the furnishings, with tastefully arranged decorative accents.

Apartment in Panamá

4.93 out of 5 average rating, 265 reviews

Modern apt ocean view in heart of Panamá yoo tower

Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Guest favorite

A balcony is featured with two stylish chairs and a small side table. Lush treetops are visible below, with a vibrant urban skyline in the background. Natural light illuminates the space, creating a serene outdoor setting for relaxation.

Apartment in Panamá

5 out of 5 average rating, 10 reviews

Cozy 1BR•Balcony Gym Rooftop Pool•Near Multiplaza

➤ Charming apartment, warmly decorated, balcony with enchanting views of lush treetops with the city's vibrant skyline in the distance. Minutes away from Multiplaza Mall . ★ Perfect for Remote Workers, 500 MB speed internet. ★ Walk 5-10 mins to Restaurants, Supermarkets, Multiplaza Mall, Cafes & Shopping ➤ Urban Escape - Building Highlights: ★ Gym ★ 2 Co-Working Spaces ★ Pool on the Rooftop Terrace ➤ Located in San Francisco: Explore the City Easily | Uber-Friendly

Guest favorite

A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.

Apartment in Panamá

4.98 out of 5 average rating, 148 reviews

Escápate al Corazón de Casco con Balcón Privado

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Guest favorite

A private terrace features a small pool and sunbeds surrounded by greenery. A wooden deck extends alongside the pool, and a folding table with two chairs is visible. In the background, architectural details of neighboring buildings and a church tower can be seen against a blue sky.

Apartment in Panamá

4.75 out of 5 average rating, 335 reviews

Jacuzzi & Private Rooftop recently refurbished D11

Welcome to Casa Diez, the most romantic spot in the Old Town! Enjoy a unique experience in this room for two, featuring an exclusive outdoor Jacuzzi overlooking the starry sky. Relax in a comfortable queen-size bed, with a private bathroom, air conditioning, Smart TV, and Wi-Fi. You'll also have access to a beautiful shared pool and laundry center, exclusively for our guests. Enjoy an unforgettable stay in a cozy, intimate, and fully equipped setting.

Guest favorite

Apartment in Panamá

4.94 out of 5 average rating, 17 reviews

Céntrico y seguro + rooftop con piscina y vistas

Apartamento moderno de 1 dormitorio en zona segura, estratégica y súper céntrica de Ciudad de Panamá. A solo 5 min caminando del Metro (Vía Argentina) y rodeado de restaurantes, supermercados, cafés, bancos y más. Ideal para nómadas digitales, viajeros de negocios, turistas o parejas. Diseño acogedor y funcional, perfecto para estancias cortas o largas. Disfruta de comodidad, estilo y una ubicación inmejorable para explorar o trabajar en la ciudad.

Top guest favorite

A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.

Home in Las Colinas de Caceres de Arraijan

4.98 out of 5 average rating, 217 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.