Guesthouse vacation rentals in Mission Bay, San Diego

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Mission Bay, San Diego

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Guesthouse in San Diego

4.99 out of 5 average rating, 413 reviews

Lovely La Jolla Cottage Minutes from the Beach

Awesome location! Right in the heart of Bird Rock/La Jolla close to some of Southern California's best beaches! The Beach Cottage is detached and located towards the rear of our property. You will have your own private entrance with key-less entry. To access The Cottage, walk down the drive way, up the stairs to your suite. The Cottage was custom built with luxury in mind. This one-of-a-kind space provides the ultimate beach getaway! Custom doors and lighting, private balcony off your bedroom, black-out curtains, amazing shower with heated tile flooring, new super-comfortable Eastern King bed with luxury memory foam topper, remote controlled A/C and heating unit, bar sink and mini fridge, Nespresso coffee maker, tea kettle, Direct TV, closet, beach chairs and towels, and more. Unrestricted street parking. Local surf board and bike rental around the corner and if traveling with your four-legged friend, check out online sites for in-home doggie care within blocks. Walk to Bird Rock Coffee Roasters in the morning, Wayfarer Bakery and around the corner for amazing sunsets at the ocean. We are available to help with any questions or concerns during your stay. We look forward to having you! The cottage is a 4-minute walk from the ocean that has a lovely park and benches to enjoy the view, the sunrise and sunset, and clean ocean air. Just steps away from some of the best coffee shops, bakery and cuisine in the Bird Rock, LaJolla neighborhood. Enjoy great bars, shops and casual dining. It’s within a very short ride to Wind n'Sea Beach as well as the sand and surf of Pacific Beach and Mission Bay. LaJolla Cove is an 8-minute car ride. Walking is the BEST way to see La Jolla! Explore the neighborhood and its architecture, see the sea lions in the Cove, shop downtown La Jolla or just hang by the beach! If you want to explore more, Uber is the best way to get around! Pacific beach is 5-min away, Mission beach is 8-min away and downtown San Diego is only 15-min away! Access to The Cottage is down the driveway, and up the stairs. No smoking on property, including private balcony and deck. Southern California is known for being especially dry and fires can spread easily. Thanks for understanding!

Sep 23 – 30

ﺩ.ﺇ1,170 per night

Guest favorite

Guesthouse in San Diego

4.97 out of 5 average rating, 344 reviews

Diamond Villa in the Heart of Pacific Beach

3 blocks to the beach & 2 blocks off main st, newly constructed detached living space w/private entrance & shared yard: spacious 1 bedroom, 1 bath, lg living rm w/an accordion glass door to patio/deck, 2 flat screen TVs w/cable & wifi , leather sofas, gas fireplace, kitchenette, gas grill, propane heater on deck, top level has wet bar, chairs & gas fit pit, bay & ocean peek views from top level, private entrance, outdoor warm shower for after beach rinse, Jacuzzi & wood fire pit in shared yard

Oct 22 – 29

ﺩ.ﺇ514 per night

Guest favorite

Guesthouse in Bay Park

4.98 out of 5 average rating, 118 reviews

Casita Hermosa - Close to everything in San Diego

Stay in the quiet beauty of your own guest house and private garden patio. Recently remodeled, Casita Hermosa will delight your senses and relax your soul. Features include a private bedroom, living room, dining area, fully equipped kitchen, and a full bathroom. The entire unit will immerse you in the southern California lifestyle as you marvel at the decorative touches featuring surf, ocean, sun, beaches, and all the best that San Diego has to offer plus a nod to our southern neighbor, Mexico!

Nov 3 – 10

ﺩ.ﺇ654 per night

Guest favorite

Guesthouse in Pacific Beach

4.91 out of 5 average rating, 835 reviews

Pacific Beach Private Zen Hideaway Bikes Included

Beautiful bright, centrally located spacious studio unit. 2 Beach Cruisers come with Unit. Smoking/420 allowed on private patio which overlooks our little zen garden. Spa like shower. Easily find safe street parking right in front of property. Fireplace use for Winter, AC for Summer. Hop on the beach cruisers head to the beach 1.3 miles away or the great bars of PB. Pillow Top Luxury Mattress. 55 inch Sony TV w Apple TV. Snacks, Water, Coffee. Beach Towels, cooler and beach chairs provided.

Oct 11 – 18

ﺩ.ﺇ694 per night

Guest favorite

Guesthouse in San Diego

5.0 out of 5 average rating, 108 reviews

Santorini-Inspired Cottage #1 w/ Hot Tub + Views

Travel 16 steps up a Greek-inspired curving stairway with two-story high walls to your tucked-away cottage built into the hillside villa of Alta Colina. With spectacular views, step onto the front private balcony to watch planes take off & boats sail around the harbor. End the night in front of your secluded back patio fireplace or climb the steps of your spiral staircase to the rooftop Jacuzzi. Design & details inspired by European travel, it'll be hard to believe you’re still in San Diego.

Oct 24 – 31

ﺩ.ﺇ1,201 per night

Guest favorite

Guesthouse in San Diego

4.98 out of 5 average rating, 187 reviews

Mission Bay house/modern, private, stand alone

Find complete peace in this newly constructed private house. A modern design. No shared walls with anyone. Inside is a warm and cozy. living room, kitchen and inviting bedroom. Go through the patio doors and enjoy the view from a private deck overlooking the neighborhood. Next to Mission Bay and minutes from Sea World, the ocean, boardwalk, Historic Old Town, Balboa Park, the zoo, the airport and downtown. Cozy for a couple and comfortably sleeps 3 guests. Indoor and outdoor dining spaces.

Oct 19 – 26

ﺩ.ﺇ591 per night

Guest favorite

Guesthouse in San Diego

4.93 out of 5 average rating, 356 reviews

Cozy Ocean Beach Casita

This cozy, clean casita is just 4 blocks to the beach, pier, great surfing, restaurants, bars, shopping, and Sunset Cliffs. You’ll love it for its walkability to everything you need. The casita is only 120 square feet, a very small space (small studio with everything in one room including the bathroom), for single occupancy only, but with everything you need to enjoy a San Diego getaway. It is great for solo travelers who want to be near the heart of Ocean Beach, San Diego, California.

Sep 29 – Oct 6

ﺩ.ﺇ395 per night

Guest favorite

Guesthouse in San Diego

4.91 out of 5 average rating, 355 reviews

La Casita - Fully Updated Casita in Mission Hills

This well designed, fully updated detached studio casita is located in one of the most sought after neighborhoods in San Diego - Mission Hills. Surrounded by a serene garden courtyard with private entry and quiet patio. Close to great dining, grocery stores and shopping, and a mere 10 minutes or less to most of San Diego’s main attractions. If you are coming by car, there is plenty of free street parking - otherwise Ubers are plentiful and reasonably priced.

Oct 7 – 14

ﺩ.ﺇ458 per night

Guest favorite

Guesthouse in San Diego

4.89 out of 5 average rating, 644 reviews

South Mission Beach Zen-Like Studio

This fully furnished second story South Mission bayside studio offers relaxed beach living. This studio sleeps 2 (Queen Bed) & 2 Boogie Boards are provided; private off street parking on premise. Bbq grill on small balcony. The unit is steps to the bay and short three minute stroll to the beach. Two beach cruiser bicycles provided which is one great way to get around the area. Please note, access to the second story is via an outdoor spiral staircase.

Jun 22 – 29

ﺩ.ﺇ825 per night

Guest favorite

Guesthouse in San Diego

4.95 out of 5 average rating, 146 reviews

Sparkling Clean Studio w/AC & Private Deck

Thank you for checking out our Amazing Beach-Chic studio located in the heart of PB. Our recently remodeled studio is 7 blocks to the ocean and walking distance to restaurants, bars, shopping and, nightlife. The studio is bright and open with tons of space, your own private deck, and brand new everything! Enjoy 650 thread count luxury cotton linens, pottery barn duvet cover, feather duvet, and air conditioning.

Dec 5 – 12

ﺩ.ﺇ659 per night

Guest favorite

Guesthouse in Pacific Beach

4.96 out of 5 average rating, 167 reviews

Chez Christy

Cozy, quiet studio in the heart of Pacific Beach. Quick access to beaches, Pacific Beach Pier, Mission Beach, Mission Bay, shops, bars, and restaurants. Miles of walking and biking paths skirt the water; recreational opportunities abound. Fast & reliable WiFi and proximity to UCSD make this an ideal place for visiting professionals. We offer extended stay discounts as well, automatically applied.

Sep 23 – 30

ﺩ.ﺇ600 per night

Guest favorite

Guesthouse in San Diego

4.98 out of 5 average rating, 240 reviews

2 Free Bikes, Pvt Parking, Steps to Beach

🔹Steps to the Boardwalk, Beach and Bayside 🔸ONE min walk - 2 cafes, 2 bars, a mini-market grocery store, and a liquor store 🔹Dedicated Parking pot 🔸Beach cruiser bikes included 🔹FIVE min walk to Belmont Park amusement park 🔸NINE min drive to SeaWorld 🔹Cuban Tropicana Style 🔸Umbrella, Beach Chairs & Towels 🔹Fully Stocked Kitchenette 🔸Mixology set 🔹Spa like shower

Oct 15 – 22

ﺩ.ﺇ1,159 per night