
House vacation rentals in Mission Bay, San Diego
Find and book unique houses on Airbnb
Top-rated house rentals in Mission Bay, San Diego
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Mission Bay, San Diego house rentals
House rentals with a pool

3 BR Urban Oasis with Pool and Spa in Great Area
I am a San Diego local, but my family was coming to town and we needed more space. I picked this place because I knew my sister and brother-in-law would love being able to walk to all the restaurants and brewery nearby and my 6 year old nephew would get a lot of use out of the pool. The place exceeded my expectations, it was perfect for everyone. We spent a lot of time in the backyard swimming or playing board games, and my Mom got a lot of use out of the hot tub. Communication with the host was excellent and the place was comfortable and clean. The only downside is my family might visit too often now!

Private 3 bedroom block to Bay New Pool Spa, Bikes
Beautiful home with plenty of space. Vanessa was very responsive and helpful with check in. I had made a request to check in early due to travelling with an infant and when I arrived she had a packnplay and a high chair set up for me. The house had several toys/books for kids along with beach chairs and shades for us to use. The pool and spa was beautiful and kept very clean. There is also a walking path at the end of the street that goes along the beach and leads to pacific beach within 15-20 minutes. Its hard to find a house this spacious and close to pacific beach for this price, would highly recommend to anyone. The host was incredibly friendly and responsive to messages which is always nice when travelling from far away.

Resort Style Living with Pool, Spa, and Bay Views!
Great place to stay! Very clean and great pool for the family! Close to SeaWorld and Malls! Definately would stay here again and Brian was a great host and very responsive when we needed him.

Your Modern Lux Pool Resort in the Heart of SD
Stay at Katri’s was great. Had delicious cookies waiting for us when we checked in, which was a breeze. House was spacious and entire lot was very big. Pool was great and even after we had told them that no heated pool would be necessary, Mother Nature had a different idea and gave us some more than unexpected chilly weather, so they had no problem throwing the heater on for us. Freeway in the background was hardly a noise problem for us personally. Just far enough that it didn’t affect us, and was nice to see what our morning commute was going to be like. Brought two dogs with the group that absolutely loved everything (after one of them finally got over his fear of the staircase). All in all a great stay in a great neighborhood. Cant comment more how quickly they responded to us in the days leading up to the trip, and while we were there. Great hosts!

Lionhead - Private Boutique Home
Great location and the house had everything we needed. beautiful home, nice decoration and really nice view from the jacuzzi.

University Heights Oasis Getaway
Exactly as the other reviewers have described, it is just a beautiful oasis in a perfect quiet neighborhood. Don’t wait, book now!

PB Dream HOUSE Steps to Beach Bay ❤️Modern Private
The location is a ten minute walk to the beach. There’s a sprouts three minutes away and numerous bars, restaurants, and shops. The house was clean and had everything we needed. Great location with a very great host. Very kind people. I would definitely stay again.

Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit
I never leave reviews but had to for this home. Truly the most wonderful experience! Stayed for my sister’s bachelorette, and the backyard was even more incredible than pictured!! Every guest wished we could extend our stay, and my sister and I are already talking about trying to return to this exact home for a future family vacation.
Weekly house rentals

Luxury Resort: Pool, Spa, Swim-Up Bar & Bay Views
The pool area is amazing and very well designed. The inside of the home has high end amenities, and we really enjoyed our stay. Just a heads ups as far as the heated pool, it is an extra service and not included. It is $250 per day to heat the pool. Other than that not being clear in the booking, it’s an amazing home and wouldn’t hesitate to stay again.

Luxury Condo Mission Beach, 3BR/2BA, Steps to Sand
Thanks Benny. Our boys had a great time. I hope you found the remote. The boys did not have it or take it.

40 Steps to Ocean | Pristine, Lux, AC, Garage, BBQ
We had a wonderful stay! Home was steps from the bay and a very short walk to the ocean. Coast Vacation Homes customer service was excellent. They were very friendly and quick to respond if we needed anything. We hope to be back soon!

Oceanfront Condo 2/2 | Hot Tub | Private Roof Deck
We really enjoyed our stay here. Obviously, we stayed here for the ocean view and roof top terrace which did not disappoint. It is within walking distance to fun activities and places to eat. It is also close enough to some great restaurants within 2-3 miles (we used Lyft which averaged about $6-10 each way). The place was clean and the beds were comfortable. There was ample space for 3 adults and a teenager. There were plenty of things to do with a nice mix of peace (from the absolutely wonderful roof top terrace) and entertainment (groups on the boardwalk, Belmont Park, SeaWorld, and the Zoo). Any questions we had, Erin or Christina were quick to respond. We had an issue with hooking up the AC unit due to a piece missing that was apparently being cleaned. Within 1 hour Erin arrived with a new piece and hooked it right up for us. Amazing service! If we found ourselves in SD again, we'd definitely stay here and recommend for others!

Beachside Cottage just steps to ocean Blue
Thank you Avery and Scott for welcoming my little family into your space. It was such a wonderful trip and I’m so happy to have come across your listing. We enjoyed our stay and being walking distance from the beach, coffee shop and so many restaurants and shops by your home! :)

Beach House | Walk to Bay | Patio & Open Living
The space was very clean, beautifully decorated, and exactly as described in the listing. The host was incredibly responsive and made check-in smooth and hassle-free. The location was perfect: quiet, safe, and close to everything we needed. We would absolutely stay here again and highly recommend it to anyone looking for a comfortable and relaxing getaway.

PB Cottage w/ Parking + Hot Tub + Fire Pit
We had a great stay! We loved the house - the bed and couch were comfy, and the yard was so great! The house had thoughtful touches, and it's a super walkable location in PB. I would definitely stay again :) Communication was also very easy, we had a few questions and they got back to us right away which made everything really easy.

On The Beach Casita - Bay front access
Gorgeous Airbnb on an almost private beach. Location is great for those who know the area. Only one bedroom and patio space is shared with other unit. But the view and serene environment made up for it :)
Private house rentals

1 Bedroom Sanctuary
We absolutely loved our stay here. The location was great. Close to the beach and so many great restaurants within walking distance. Quick drives to other parts of San Diego if looking to go elsewhere, but we felt the area really had everything we could need! Alyssa was proactive about checking in during our stay and gave us great recommendations. The unit was very cozy and clean. A great place to relax after spending the day at the beach. The patio is quite large and a lovely place to enjoy meals and the fresh air. Highly recommend and we hope to be back soon!

Shadow House Mt. Helix
The most beautiful Airbnb! The location was amazing, it was very secluded. The hosts make you feel right at home.

NEW Luxury Meets Beach | BayFront + HotTub/Firepit
Despite the gloomy June weather we had a great time in Mission Beach. This house was right on the cove side, so not as windy or as loud as staying on the ocean side. Easily able to walk anywhere in Mission Beach up to Pacific Beach. The hot tub was nice to relax in on cool evenings and the house was comfortable, lots of outdoor space with balconies off every room. The only unexpected thing (maybe I missed it in the listing) is that on the top floor you have to walk through a bedroom to get to the 3rd bedroom but it wasn't a big deal. Japanese toilet was a big hit! Will definitely consider staying here again.

Renovated private ADU & spa, Mission Bay/ SeaWorld
Everything we could possibly need. Garage, hot tub, king size bed, private, mini splits AC in living room and bed room, and more! Not to mention the hosts, Darren & Tom are so friendly and accommodating — leaving snacks, kindness, and thoughtful additions to your stay. Everything was comfortable, clean and excellent. Will be looking forward to returning!

PB Retreat, Surf, Sun, Sand
Great place near pacific beach and mission beach, parking was a bit confused at first but it was great after found out about it

Beach Cabin, Steps to Beach/Bay
Great location! Very walkable to lots of spots in Mission Beach and right by the beach. The space had everything we needed and the outdoor seating made for a great area to hang out!

Point Loma Hillside Retreat, Pacific Ocean Views
We had an absolutely amazing stay - great location, beautiful view, wonderful and inviting home.

Breezy Bayside Cottage
We had a great stay at this home! It’s a perfect location close to everything. The home felt very clean and looks just like the pictures, everything is new and updated. NXT was a great host, check-in was a breeze and we were even able to check in much earlier than expected which worked out great for us. Would definitely stay here again!
Quick stats about house rentals in Mission Bay, San Diego
Total rentals
840 properties
Nightly prices starting at
ﺩ.ﺇ147 before taxes and fees
Total number of reviews
42K reviews
Family-friendly rentals
730 properties are a good fit for families
Pet-friendly rentals
270 properties allow pets
Rentals with a pool
10 properties have a pool
Destinations to explore
- Townhouse rentals Mission Bay
- Rentals with outdoor seating Mission Bay
- Rentals with lake access Mission Bay
- Beach house rentals Mission Bay
- Rentals with a patio Mission Bay
- Guesthouse rentals Mission Bay
- Family-friendly rentals Mission Bay
- Waterfront rentals Mission Bay
- Apartment rentals Mission Bay
- Rentals with a kayak Mission Bay
- Cottage rentals Mission Bay
- Rentals with an EV charger Mission Bay
- Rentals with a fire pit Mission Bay
- Rentals with a hot tub Mission Bay
- Beachfront rentals Mission Bay
- Condo rentals Mission Bay
- Pet-friendly rentals Mission Bay
- Rentals with pools Mission Bay
- Rentals with a sauna Mission Bay
- Rentals with breakfast Mission Bay
- Rentals with a fireplace Mission Bay
- Rentals with beach access Mission Bay
- Smoking-friendly rentals Mission Bay
- Fitness-friendly rentals Mission Bay
- Rentals with a washer and dryer Mission Bay
- Kid-friendly rentals Mission Bay
- Rentals with a beach view Mission Bay
- Hotel rentals Mission Bay
- House rentals San Diego
- House rentals San Diego County
- House rentals California
- House rentals United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Rosarito Beach
- Oceanside City Beach
- Belmont Park
- Tijuana Beach
- Torrey Pines State Beach
- Pacific Beach
- Coronado Beach
- San Clemente State Beach
- SeaWorld San Diego
- Coronado Shores Beach
- Oceanside Harbor
- San Onofre Beach
- University of California San Diego
- LEGOLAND California
- Black's Beach
- San Diego Zoo Safari Park
- Balboa Park
- Trestles Beach
- Pechanga Resort Casino
- Liberty Station
- Sesame Place San Diego
- Moonlight Beach
- Playas Los Buenos
- USS Midway Museum