
Vacation rentals in Mesquite
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Top-rated vacation rentals in Mesquite
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Quaint casita for 2
*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Tiny Cute Cubby in Telshor Hills, Private Entrance
The Cubby is perfect for overnight or short-term stays. Zero contact check-in and check-out. Access to central Las Cruces. Close to NMSU, Mesilla Valley Mall, major medical centers, and major event facilities. Located in Telshor Hills, a quiet neighborhood with plenty of mature trees and vegetation. Close proximity to observatory, minimal light pollution. Gorgeous views of Organ Mountains and Tortugas Mountain (A Mountain). Ten minute drive from historic Mesilla. Close to various hiking trails.

Desert Oasis with Pool
Pueblo Style home on 1+ Acre with Pool! This charming 4BR/2BA Pueblo Style home features stunning details throughout. Gorgeous saltillo tile in the living areas with beautiful wood beam accents, and a kiva-style fireplace for cozy winter nights. The primary suite offers direct access to the covered patio for summer dips in the pool and evening Sunsets. The 4th bedroom is huge and could be used as a second living area. The pool is not heated but will be open and cleaned all year. Sorry no pets.

Ocotillo Casita in Historic Mesilla.
Mesilla STR Permit #0830 We've renovated 90-year-old historic structures to create sustainable, environmental friendly spaces with rainwater harvesting, solar energy, electric solar-powered car charger. This renovated adobe casita is the 2nd structure after our main house. The 3rd is a smaller vacation rental called Yucca Casita. We are within 2 blocks of the historic Mesilla plaza with its farmers market, shops, galleries, restaurants, and walking trails along historic acequias (canals).

Casita Azul, stunning beauty in the desert.
This Adobe Casita is at the foot of the impressive Organ Mountains. The views are stunning, sunrises, sunsets, star filled evenings, and moon risings. The casita includes an enclosed courtyard with a kiva fireplace, laundry facility. Located on 6 acres of the Chihuahuan desert, adjacent to owners' home, who is always available, with nearest neighbors nearly one half mile away. So quiet, only birds, and the occasional coyotes can be heard, a spiritual retreat for those in need of respite.

Raven's House
Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Airstream Airdream w hot tub!
Welcome to the “Retro Retreat,” a 1968 Land Yacht infused with NM’s enchantment. This vintage stay has been lovingly curated with elements of nostalgic Americana and contemporary desert chic, featuring vintage books, games, and iconic art. This fully restored tiny stay set amidst a pecan field in the Mesilla Park district offers modern amenities including a remodeled bathroom with shower, Wi-Fi, Smart TV, a mini-split for easy heating and cooling, and a private hot tub for relaxation.

1 bed cute casita near NMSU, pet friendly
Amazing details throughout this small but mighty space. You have all you need for a quick trip or a longer stay. 1 bedroom with a queen, full-sized kitchen, living room, and dining space as well as a fully fenced, pet-friendly yard. Be immersed in local culture with Talavera tile and Saltillo floors as well as vigas and rough-hewn ceilings and accent walls. The guest house is close to the main house but completely separate and private. Off-street, private parking.

Pecan Palace – Luxe 4BR w/ Hot Tub, Game Room & EV
Pecan Palace: luxe 4-BR near NMSU & White Sands. Tucked by pecan farms, this new retreat blends comfort + fun. Perfect for families, work trips, extended stays. ☞ EV charger ☞ Backyard hot tub under pergola ☞ Climate-controlled game lounge with pool table ☞ Foosball ☞ Poker ☞ Pac-Man ☞ Fully equipped chef's kitchen ☞ Plush bedrooms with blackout curtains ☞ Prime spot—1.5 mi to NMSU, Interstate I-10, dining & shopping ☞ Easy access to White Sands NP and downtown

4 Bedroom Contemporary Model home
This fully-furnished modern home is perfect for weekend getaways or longterm stays. With 4 bedrooms and plenty of space The Dove Escape offers the comfort of home with a luxury feel. This stylish modern space is perfect for families, groups, or anyone seeking a retreat at the end of long day in Las Cruces or a break from the road. The Dove escape is minutes from NMSU and the University Corridor with all it has to offer.

The Desert Dome @ BNC Farms
Welcome to the Desert Dome! We are located in small village of Chaparral, NM. This is a great spot to get away from the hustle and bustle of life while still having all the city amenities close by. You can find lots of hiking and biking trails in the area. We love furry friends, and would be happy to have your pets here too. There is a fenced in back area for their use. All pets must be leashed if not in the fenced area.

Cozy Casita De Mesilla (Mesilla Cottage)
Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.
Popular amenities for Mesquite vacation rentals
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Vacation Home

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