Vacation rentals in Doña Ana County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Doña Ana County

Guests agree: these stays are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Guesthouse in Las Cruces

4.97 out of 5 average rating, 195 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill. Onsite owners as casita is adjacent to our main home.

Jul 15 – 22

ﺩ.ﺇ304 per night

Guest favorite

Townhouse in Las Cruces

4.99 out of 5 average rating, 114 reviews

The Ritz Spa Sanctuary hot tub/patio/fam/pet

Come unwind and rejuvenate at our zen sanctuary, where relaxation, simplicity, and comfort are key to a great stay! Pamper yourself in our spa like walk-in rain showers! Enjoy our newly remodeled contemporary interiors with natural terrecota concrete throughout. Private patio enjoy grilling with friends and family or spend a romantic evening sitting around the fire table or in the Hot tub! NMSU 5mi, White Sands 45mi, Less than 1 min access to Hwy-70, I-10,I-25 Old Mesilla 5mi, sec to Hospital

Dec 18 – 25

ﺩ.ﺇ422 per night

Guest favorite

Guesthouse in Las Cruces

5.0 out of 5 average rating, 214 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Oct 6 – 13

ﺩ.ﺇ324 per night

Guest favorite

Shipping container in Las Cruces

4.91 out of 5 average rating, 961 reviews

Nature Retreat 12-min from Downtown (with pool)

Re-purposed 40-foot shipping container w/Ikea cabinets & furniture at edge of desert. Loft is 1 of 2 dwellings on 5-acre lot, private exterior doors & adjacent reserved parking. Picture window with wonderful view of Organ Mountains. Compact kitchen, Serta PillowTop queen size bed, full bathroom, LED lighting, cooled/heated by modern heat pump, Wi-Fi Internet. Pool access in season (usually April-October). Hike/bike from doorstep. Pet-friendly, see House Rules for details/cost.

Jun 13 – 20

ﺩ.ﺇ369 per night

Guest favorite

Townhouse in Las Cruces

4.95 out of 5 average rating, 419 reviews

Cul-de-sac Condo

You'll enjoy staying in this modern townhouse enjoy a glass of wine in the covered patio while taking in the New Mexico sunsets. Pet free, smoke free. Fully equipped kitchen with everything you'll need to prepare meals. Spacious 2 bedrooms , 2 full bathrooms. Smart TV's with Roku, access to garage, washer/ dryer. In friendly quiet cul de sac neighborhood with minimal traffic. Easy access to Interstates 10, 25, and Highway 70. Close to restaurants, movie theater, shopping.

Oct 20 – 27

ﺩ.ﺇ376 per night

Guest favorite

Guesthouse in Las Cruces

4.97 out of 5 average rating, 232 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Jun 28 – Jul 5

ﺩ.ﺇ497 per night

Guest favorite

Guesthouse in Las Cruces

4.97 out of 5 average rating, 258 reviews

Clara's Nest - The Gem of Hacienda de Las Cruces

Clara’s Nest is in a 1880's adobe compound with its own private entry, courtyard, original stone floors, handcrafted beams, hand-painted bird & flower motif throughout. The suite features a king bed, cozy loveseat & ottoman in the sleeping area, dining table & 4 chairs, kitchenette with micro, fridge, coffee & tea bar, a separate living room with sofa, TV, private bath. Outer space includes: covered patio, backyard, pool and hot tub area (heated upon request) No stove.

Apr 5 – 12

ﺩ.ﺇ549 per night

Guest favorite

Home in Las Cruces

4.97 out of 5 average rating, 144 reviews

Charming Adobe One Block from the Mesilla Plaza

Beautiful, private casita built in the 1930's one block from the plaza. Historic charm with modern conveniences. Perfect for quiet retreat. Fenced flagstone patio in back yard fully equipped with gas grill, outdoor fireplace, outdoor dining area and french doors opening from the house. Large front yard fully enclosed. Full front porch creates shade for chair. This house is peaceful but just steps from the fiestas and activities on the historical Mesilla Plaza.

Jul 14 – 21

ﺩ.ﺇ400 per night

Guest favorite

Guesthouse in Las Cruces

5.0 out of 5 average rating, 119 reviews

Yucca Casita in Historic Mesilla

We have created a vision for this property of sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Mar 30 – Apr 6

ﺩ.ﺇ287 per night

Guest favorite

Dome in Chaparral

4.97 out of 5 average rating, 230 reviews

The Desert Dome @ BNC Farms

Welcome to the Desert Dome! We are located in small village of Chaparral, NM. This is a great spot to get away from the hustle and bustle of life while still having all the city amenities close by. You can find lots of hiking and biking trails in the area. We love furry friends, and would be happy to have your pets here too. There is a fenced in back area for their use. All pets must be leashed if not in the fenced area.

Aug 18 – 25

ﺩ.ﺇ382 per night

Guest favorite

Guesthouse in Las Cruces

4.95 out of 5 average rating, 949 reviews

Cozy Casita with Patio

Cozy casita (guest house) with patio in nice quiet neighborhood close to NMSU, Convention center, Memorial Hospital, Mountain View Hospital, Old Mesilla, ,wine country, shopping, convenient to White Sands, hiking, etc. Casita has private entrance, private bath, small refrigerator, TV, coffee maker, microwave, and wifi

Mar 10 – 17

ﺩ.ﺇ132 per night

Guest favorite

Home in Las Cruces

4.88 out of 5 average rating, 140 reviews

Casa La Jolla

Cozy 3 bedroom, 2 bath home in a quiet neighborhood in Las Cruces, NM. Close to downtown and not far from the University. Recently refurbished interior with new paint, new walk-in showers in both baths. Washer and dryer on site. Huge pet friendly backyard. Covered carport.

Apr 3 – 10

ﺩ.ﺇ379 per night