Guesthouse vacation rentals in Doña Ana County

Quaint casita for 2

*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Family · Location · Solo travel

Relax in the ❤️ of Old Mesilla. Close to plaza.

Welcome to Casa de Martiana! This gorgeous casita is located just a few short blocks (about 1/4 mile) from the plaza in Old Mesilla where you will find tons of great restaurants (mostly delicious Mexican food), wineries, bars, unique shopping and fun events. There is a market in the square on Fridays and Sundays with neat jewelry, art and other local treasures. The area is rich in history and culture and has many tales of days when Billy the Kid and Pat Garrett used to wonder the village.

Family · Location · Decor

1 king bd with big fenced back yard pets welcome

Casita La Pacana is nestled in the middle of town surrounded by old pecan trees. Feels like the country but is in the middle of town. 1 bedroom, completely renovated casita that has 1 kind bed, a large living room, streaming TVs in both living room and bedroom, full kitchen including a dishwasher and washer/dryer, hardwood floors, authentic Talavera tile, large shower with a bench seat, huge back yard, and ample parking! This little casita has everything to be your home away from home.

Location · Family · Getting around

Casita De Cuervo

Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Location · Value · Hospitality

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Family · Location · Wifi

Casita at Old Mission near Hatch NM

Have you stayed overnight in a Church before? This is your opportunity. Your lodging in the Casita is attached to the now deconsecrated St Francis de Sales Church, surrounded by a large Spanish courtyard, garden, and a private patio and parking area. Experience the adobe spaces as built in 1860. The church compound is walled and gated. We are located 1 1/2 miles southeast of Hatch in a colonia called Rodey. Look for the bell tower from Hwy 185 and begin your experience here.

Family · Value · Amenities

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Location · Value · Solo travel

Clara's Nest - The Gem of Hacienda de Las Cruces

Clara’s Nest is in a 1880's adobe compound with its own private entry, courtyard, original stone floors, handcrafted beams, hand-painted bird & flower motif throughout. The suite features a king bed, cozy loveseat & ottoman in the sleeping area, dining table & 4 chairs, kitchenette with micro, fridge, coffee & tea bar, a separate living room with sofa, TV, private bath. Outer space includes: covered patio, backyard, pool and hot tub area (heated upon request) No stove.

Value · Family · TV

Cozy Casita w/private patio near Old Mesilla

This adorable Casita is located in a semi-rural area just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Location · Value · Indoor spaces

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Value · Location · Indoor spaces

Casa Majik

A two bedroom casita with a kitchen. We have a full bath with tub and shower. Very quiet upscale neighborhood with all custom homes on 1 acre lots. Winding streets perfect for walking or biking. Less than 50 feet from the door of Casa Majik is a trail leading to "A" Mountain. Parking is for a maximum of two cars on the property. Restaurants and Memorial Hospital are 2 miles away.

Value · Location · Check-in

Rustic Downtown Hideaway

This Rustic guest home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.

Family · Location · Kitchen