
Guesthouse vacation rentals in Doña Ana County
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Top-rated guesthouse rentals in Doña Ana County
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Quaint casita for 2
*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.
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Cozy Modern Casita-Studio!
Perfectly located in Central El Paso! Found near the Franklin Mountain range, Downtown El Paso, great restaurants, sporting arenas, multiple hospitals, Fort Bliss Army base, and much more! Conveniently near multiple freeways for quick access to surrounding locations! -Newly renovated -Equipped with new modern appliances -Washer and dryer -Refrigerated air and heating -Comfortable queen bed -Sleeper sofa to accommodate a 3rd guest or children -Pack n’ play available for extra fee by request
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Relax in the ❤️ of Old Mesilla. Close to plaza.
Welcome to Casa de Martiana! This gorgeous casita is located just a few short blocks (about 1/4 mile) from the plaza in Old Mesilla where you will find tons of great restaurants (mostly delicious Mexican food), wineries, bars, unique shopping and fun events. There is a market in the square on Fridays and Sundays with neat jewelry, art and other local treasures. The area is rich in history and culture and has many tales of days when Billy the Kid and Pat Garrett used to wonder the village.
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Ocotillo Casita in Historic Mesilla.
Mesilla STR Permit #0830 We've renovated 90-year-old historic structures to create sustainable, environmental friendly spaces with rainwater harvesting, solar energy, electric solar-powered car charger. This renovated adobe casita is the 2nd structure after our main house. The 3rd is a smaller vacation rental called Yucca Casita. We are within 2 blocks of the historic Mesilla plaza with its farmers market, shops, galleries, restaurants, and walking trails along historic acequias (canals).
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Raven's House
Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.
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Desert Peaks Casita
This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.
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Getaway Guesthouse in Historic Mesilla
Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.
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Clara's Nest - The Gem of Hacienda de Las Cruces
Clara’s Nest is in a 1880's adobe compound with its own private entry, courtyard, original stone floors, handcrafted beams, hand-painted bird & flower motif throughout. The suite features a king bed, cozy loveseat & ottoman in the sleeping area, dining table & 4 chairs, kitchenette with micro, fridge, coffee & tea bar, a separate living room with sofa, TV, private bath. Outer space includes: covered patio, backyard, pool and hot tub area (heated upon request) No stove.
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Cozy Casita w/private patio near Old Mesilla
This adorable Casita is located in a semi-rural area just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.
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1 bed cute casita near NMSU, pet friendly
Amazing details throughout this small but mighty space. You have all you need for a quick trip or a longer stay. 1 bedroom with a queen, full-sized kitchen, living room, and dining space as well as a fully fenced, pet-friendly yard. Be immersed in local culture with Talavera tile and Saltillo floors as well as vigas and rough-hewn ceilings and accent walls. The guest house is close to the main house but completely separate and private. Off-street, private parking.
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Casita de Colibrí | Hot Tub • Walk to Old Mesilla
Escape to Casa de Colibrí, a private Southwest-inspired casita just a short walk from the historic Old Mesilla Plaza, restaurants, cafés, shops, and local attractions. Relax in your private hot tub, unwind on the peaceful patio, and enjoy a comfortable stay with fast Wi-Fi, a cozy bed, and thoughtful amenities. Whether you’re here to explore Las Cruces or simply relax, Casa de Colibrí is the perfect home away from home.
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Rustic Downtown Hideaway
This Rustic guest home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.
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Popular amenities for Doña Ana County guesthouse rentals
Family-friendly guest house rentals

The Calm Landing - Private stay 5 min from airport
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The Blue Door Studio | Modern & Cozy El Paso Stay
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Cozy, Fenced in Casita in the Alameda District!
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Beautiful 1 Bedroom Apartment Suite in El Paso Tx!
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Starry Mountain View Central EP. Hospitals nearby!
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Route 66 Cozy Studio
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Guesthouse Fairacre's
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Rinconcito Rios
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Guest house rentals with a patio

Stylish Casita in Great Location
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Stylish Casita in the Heart of El Paso
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Cozy Guesthouse - Central EPTX
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Sunrise Casita
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Relaxing Private1 Bed 1 Bath With Non-Heated Pool
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The Loft
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Private studio w/ scenic view near downtown
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Vacation Home
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Guest house rentals with a washer and dryer

No Cleaning Fee; Casita Bougainvillea; EV+Views!
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Casa Majik
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Cozy loft hideaway near Ft. Bliss & I-10
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Comfy horse sanctuary guesthouse
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Jackie's Casita
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The Burning Tree Studio
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Riverwood Casita
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A Stylish Casita in El Paso w/Queen Bed + MNT View
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