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Family-friendly vacation rentals in Mesilla

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Mesilla

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
The living area showcases rich wood flooring, a vibrant patterned sofa, and a dark wooden coffee table. A dining area with a round table and four chairs is visible. The walls feature deep maroon accents and framed artwork, creating a cozy and inviting layout.
Home in Mesilla Park
4.94 out of 5 average rating, 260 reviews

Charming 1930 home near NMSU/ Mesilla

Sunny two bedroom one bath house on a quiet tree lined street in Mesilla Park. Enjoy this peaceful retreat close to everything. Conveniently located near the Mesilla Plaza, NMSU, and the Convention Center. Refrigerated air set up on the Nest system. The house has internet access. The wood floors, sash windows and front screen porch give this house the character we fell in love with. We've tried to decorate it to feel like home, and provide all the amenities you might need while you're staying.

Top guest favorite
An aerial view of a Pueblo Style home is presented, showcasing a serene pool surrounded by a spacious outdoor area. The home is set against a backdrop of rolling hills and a cloudy sky. Desert vegetation is seen throughout the landscape, enhancing the natural beauty.
Home in Las Cruces
4.96 out of 5 average rating, 163 reviews

Desert Oasis with Pool

Pueblo Style home on 1+ Acre with Pool! This charming 4BR/2BA Pueblo Style home features stunning details throughout. Gorgeous saltillo tile in the living areas with beautiful wood beam accents, and a kiva-style fireplace for cozy winter nights. The primary suite offers direct access to the covered patio for summer dips in the pool and evening Sunsets. The 4th bedroom is huge and could be used as a second living area. The pool is not heated but will be open and cleaned all year. Sorry no pets.

Guest favorite
A private porch area features colorful blue chairs and a grill, providing a relaxed outdoor space. A hot tub is visible to one side, and the vintage Airstream reflects sunlight with its polished exterior. String lights overhead enhance the inviting atmosphere.
Tiny home in Mesilla Park
4.93 out of 5 average rating, 284 reviews

Airstream Airdream w hot tub!

Welcome to the “Retro Retreat,” a 1968 Land Yacht infused with NM’s enchantment. This vintage stay has been lovingly curated with elements of nostalgic Americana and contemporary desert chic, featuring vintage books, games, and iconic art. This fully restored tiny stay set amidst a pecan field in the Mesilla Park district offers modern amenities including a remodeled bathroom with shower, Wi-Fi, Smart TV, a mini-split for easy heating and cooling, and a private hot tub for relaxation.

Top guest favorite
A spacious room features traditional Southwestern adobe walls and exposed wooden beams. A four-poster bed is adorned with a colorful quilt. An elegant sitting area includes vintage chairs and a decorative mirror, while natural light filters through multiple windows, creating a warm ambiance.
Guest suite in Mesilla
4.96 out of 5 average rating, 178 reviews

Josefina's Queen Suite in Mesilla Plaza.

Josefina's Queen Suite is located just off the Plaza in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our historic Southwestern design and the Garden Greenhouse, our luxurious Queen Suite offers a cozy step back in time, weaving together old world charm and modern comforts like WIFI, mini fridge, Smart TV, AC, plush bathrobes and more. If the Queen suite is already booked, please check out our King Suite!

Top guest favorite
The exterior of the guesthouse features a welcoming entrance with a turquoise door framed by two wooden columns. A small seating area with two chairs is positioned on the porch, accompanied by potted plants and a tiled floor. The sky above displays a gentle blend of blue and white hues.
Guesthouse in Mesilla
4.97 out of 5 average rating, 395 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Top guest favorite
A bright interior features a queen bed adorned with geometric patterned bedding. Adjacent to the bed, two armchairs offer comfortable seating. A small loft area with a twin bed is visible overhead. A mirror and lamps provide additional lighting in the room.
Tiny home in La Mesa
4.97 out of 5 average rating, 220 reviews

Little House with Private Patio and Hot Tub

Our guesthouse is located on historic Highway 28, also known as the Don Juan de Onate Trail, which connects El Paso and Las Cruces. It is one of the area's most scenic routes. You can find breweries, multiple wineries, and the famous Chopes restaurant and bar along the route. The highlight of the 10-mile drive from our little house in San Miguel to historic Mesilla takes you through unique canopies of pecan trees, in the largest pecan-producing county in the nation.

Guest favorite
Two colorful planters holding purple cactus are positioned beside a large window on the exterior wall of the adobe home. The warm-toned stucco walls and terra-cotta tiled flooring add to the inviting appearance of the entryway, which is framed by traditional wooden beams above.
Home in Las Cruces
4.96 out of 5 average rating, 136 reviews

Mesilla 1869 Adobe 2 blocks from plaza

I purchased this beautiful home built circa 1869 all Adobe in May 2019 and I want to share it with you! I am living in this home as one of my primary residences but I’m traveling the world and will make it available so you can also enjoy it. Authentic wood beams “vigas” and “latillas”, original kitchen wood floor, painted cement floors (by the previous artist owner), 3 foot thick adobe interior walls. Just steps to the Mesilla Plaza, shops, restaurants!

Top guest favorite
A spacious outdoor area showcases a desert landscape with gravel and low-lying plants. A large round table is accompanied by a bright red umbrella, offering shade. The casita's entrance features a patio with seating and a welcoming purple trim, enhancing the inviting exterior.
Home in Las Cruces
4.98 out of 5 average rating, 200 reviews

Charming Adobe One Block from the Mesilla Plaza

Beautiful, private casita built in the 1930's one block from the plaza. Historic charm with modern conveniences. Perfect for quiet retreat. Fenced flagstone patio in back yard fully equipped with gas grill, outdoor fireplace, outdoor dining area and french doors opening from the house. Large front yard fully enclosed. Full front porch creates shade. This house is peaceful but just steps from the fiestas and activities on the historical Mesilla Plaza.

Top guest favorite
An adobe-style home is displayed, featuring a gravel pathway leading to an entrance framed by wooden gates. Two turquoise chairs sit beside a small table under a budding tree. Planted flowers in bright pots add color to the exterior, enhancing the welcoming appearance.
Home in Mesilla
4.98 out of 5 average rating, 173 reviews

Sombra Del Valle in Historic Mesilla.

Sombra Del Valle is a beautiful home located in a quiet neighborhood and within 5 minute walking distance to the historic Mesilla plaza and 2 minute walking distance to a Brewery and restaurant and approximately 5 minute drive to NMSU. The home is comfortable and spacious; great for family trips, honeymoons, or just a fun getaway. There is free guest private parking. Once you stay here you will want to come back; it’s a home away from home.

Top guest favorite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guesthouse in Las Cruces
4.97 out of 5 average rating, 372 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Top guest favorite
A modern interior features a wooden dining table with two black chairs, accompanied by a decorative bowl. A wall hanging adds texture, while a metal rack displays clothing and a woven basket. Natural light filters through a nearby window, highlighting the clean lines of the space.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 216 reviews

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Top guest favorite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 235 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Popular amenities for Mesilla family-friendly rentals

When is the best time to visit Mesilla?

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Avg. priceﺩ.ﺇ470ﺩ.ﺇ496ﺩ.ﺇ459ﺩ.ﺇ426ﺩ.ﺇ459ﺩ.ﺇ459ﺩ.ﺇ422ﺩ.ﺇ430ﺩ.ﺇ382ﺩ.ﺇ444ﺩ.ﺇ459ﺩ.ﺇ463
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Quick stats about vacation rentals that are family-friendly in Mesilla

  • Total vacation rentals

    Explore 40 vacation rentals in Mesilla

  • Nightly prices starting at

    Mesilla vacation rentals start at ﺩ.ﺇ294 per night before taxes and fees

  • Verified guest reviews

    Over 2,390 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    40 of Mesilla vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mesilla rentals

  • 4.9 Average rating

    Mesilla stays are highly rated by guests—averaging 4.9 out of 5!