
Family-friendly vacation rentals in Mesilla
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Mesilla
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Relax in the ❤️ of Old Mesilla. Close to plaza.
Welcome to Casa de Martiana! This gorgeous casita is located just a few short blocks (about 1/4 mile) from the plaza in Old Mesilla where you will find tons of great restaurants (mostly delicious Mexican food), wineries, bars, unique shopping and fun events. There is a market in the square on Fridays and Sundays with neat jewelry, art and other local treasures. The area is rich in history and culture and has many tales of days when Billy the Kid and Pat Garrett used to wonder the village.

Cozy,Clean,Contemporary Casita in Alameda District
Welcome to the perfect blend of Location, Comfort and Hospitality. Perfect for couples,business travelers and solo adventurers. Upon arrival you will find a sparkling clean cozy casita with small refrigerator,microwave and complimentary snacks for all guests. The room is contemporary, clean and comfortable and is located in the Alameda District of Las Cruces only a block from Breakfast hotspot “Bite of Belgium”. Casita Armijo is also walking distance from the Farmers Market and Downtown Mall.

Casita on the Camino Real.
Cozy 260 sq. ft. studio apartment that can accommodate two adults Comfortable queen bed Large closet Kitchenette includes mini fridge, microwave, toaster oven, crock pot, rice cooker, French press, bar sink, cooking utensils and complete dinner service Full bath with tub Small dining table and chairs inside Wi-Fi Radio clock & USB ports Wall unit that is both AC and heat Small outside sitting area with seating and small outdoor kitchen with grill Off street parking Coded door entrance

Airstream Airdream w hot tub!
Welcome to the “Retro Retreat,” a 1968 Land Yacht infused with NM’s enchantment. This vintage stay has been lovingly curated with elements of nostalgic Americana and contemporary desert chic, featuring vintage books, games, and iconic art. This fully restored tiny stay set amidst a pecan field in the Mesilla Park district offers modern amenities including a remodeled bathroom with shower, Wi-Fi, Smart TV, a mini-split for easy heating and cooling, and a private hot tub for relaxation.

Josefina's Queen Suite in Mesilla Plaza.
Josefina's Queen Suite is located just off the Plaza in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our historic Southwestern design and the Garden Greenhouse, our luxurious Queen Suite offers a cozy step back in time, weaving together old world charm and modern comforts like WIFI, mini fridge, Smart TV, AC, plush bathrobes and more. If the Queen suite is already booked, please check out our King Suite!

Getaway Guesthouse in Historic Mesilla
Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

1 bed cute casita near NMSU, pet friendly
Amazing details throughout this small but mighty space. You have all you need for a quick trip or a longer stay. 1 bedroom with a queen, full-sized kitchen, living room, and dining space as well as a fully fenced, pet-friendly yard. Be immersed in local culture with Talavera tile and Saltillo floors as well as vigas and rough-hewn ceilings and accent walls. The guest house is close to the main house but completely separate and private. Off-street, private parking.

Mesilla 1869 Adobe 2 blocks from plaza
I purchased this beautiful home built circa 1869 all Adobe in May 2019 and I want to share it with you! I am living in this home as one of my primary residences but I’m traveling the world and will make it available so you can also enjoy it. Authentic wood beams “vigas” and “latillas”, original kitchen wood floor, painted cement floors (by the previous artist owner), 3 foot thick adobe interior walls. Just steps to the Mesilla Plaza, shops, restaurants!

Charming Adobe One Block from the Mesilla Plaza
Beautiful, private casita built in the 1930's one block from the plaza. Historic charm with modern conveniences. Perfect for quiet retreat. Fenced flagstone patio in back yard fully equipped with gas grill, outdoor fireplace, outdoor dining area and french doors opening from the house. Large front yard fully enclosed. Full front porch creates shade. This house is peaceful but just steps from the fiestas and activities on the historical Mesilla Plaza.

Cozy Casita w/private patio near Old Mesilla
This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Yucca Casita in Historic Mesilla
Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Cozy Casita De Mesilla (Mesilla Cottage)
Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.
Popular amenities for Mesilla family-friendly rentals
Family-friendly home rentals with a hot tub

Modern Hidden Gem- HOT TUB & Organ Mtn Views/Patio

Hadley House 1 Bed/ 1 Bath Hot Tub 5 min downtown

Hot Tub + Arcade, Family‑Friendly Comfy New Home

Heated Pool HotTub GameRoom Views Near White Sands

Home in Las Cruces Casa de Flores (Flower House) Near NMSU

Pecan Palace – Luxe 4BR w/ Hot Tub, Game Room & EV

Southwest Luxe Golf Retreat + EV, Theater, Hot Tub

Vacation Home
Family- and pet-friendly home rentals

"Casa de Maíz" centrally located - close to NMSU

Casita Alegre (happy little house)

Sancho's Condo in Mesilla

Casa La Jolla

Amazing Historical Bungalow-NMSU, Mesilla

Raven's House

King Bed |Spacious house |Pets OK

Oasis Crosses | Movie Theater| 3BR
Family-friendly home rentals with a pool

Luxury Home- Pool, Views, Early Check in

Nature Retreat 12-min from Downtown (with pool)

Pet Friendly Luxury Retreat W/ Heated Pool & Spa

95° Heated Saltwater Pool | Desert Views | Pets OK

Desert Peaks Casita

Desert Oasis with Pool

Clara's Nest - The Gem of Hacienda de Las Cruces

Desert Pool Oasis-Central Location-Family Friendly
When is the best time to visit Mesilla?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ470 | ﺩ.ﺇ459 | ﺩ.ﺇ459 | ﺩ.ﺇ426 | ﺩ.ﺇ459 | ﺩ.ﺇ459 | ﺩ.ﺇ422 | ﺩ.ﺇ430 | ﺩ.ﺇ382 | ﺩ.ﺇ444 | ﺩ.ﺇ459 | ﺩ.ﺇ463 |
| Avg. temp | 4°C | 7°C | 10°C | 14°C | 19°C | 25°C | 27°C | 25°C | 22°C | 15°C | 9°C | 4°C |
Quick stats about vacation rentals that are family-friendly in Mesilla

Total vacation rentals
Explore 40 vacation rentals in Mesilla

Nightly prices starting at
Mesilla vacation rentals start at ﺩ.ﺇ257 per night before taxes and fees

Verified guest reviews
Over 2,550 verified reviews to help you choose

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
40 of Mesilla vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesilla rentals

4.9 Average rating
Mesilla stays are highly rated by guests—averaging 4.9 out of 5!
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