
Guesthouse vacation rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Spacious Casita, Quiet, Peaceful Home - No Stairs!
Cozy Casita in a beautiful, quiet neighborhood. California King bed sleeps two comfortably. 50 inch TV has cable, Netflix, DVD player with assortment of movies. Keurig coffee pot, fridge and microwave. Dining table inside. Outdoor seating opens to peaceful, scenic backyard. Parking available in the driveway. Park to the left of 2 car garage. Our Casita is a modest room that we have done our best to make comfortable for travelers who want an alternative to an impersonal hotel. No pets allowed.

Entire Suite: Private and Cozy Clark House Casita
Trade the sterile hotel vibe and feel right at home by staying at our quaint and unique historic casita. Catch up on your favorite shows in the living room with our 65 inch HD smart TV, or watch a movie while cozied up on our comfy queen size bed using the second tv in the bedroom. Our space has a kitchenette to prepare meals, and a full size bathroom. You may also relax in the shaded patio surrounded by mature trees and lush greenery. No smoking or vaping inside or outside of the property.

Luxury Modern Executive Retreat
Northeast Mesa location close to Tonto National Forest, the Salt River and Saguaro lake. 5 minutes from Boeing, Nammo Talley or MD Helicopter. 25 minutes from downtown Phoenix or Scottsdale. Nestled at the base of the Goldfield mountains. Contemporary open floor plan with modern design. Private entrance and single parking spot in front of the main house. Fast WiFi. Roku and cable TV. Beautiful, quiet neighborhood close to city amenities as well as biking and hiking trails. TPT# 21558238

Historic Firehouse Downtown Chandler Large shower
Welcome to the historic Firehouse, where you're a quick 5-minute stroll away from bustling Downtown Chandlers top-notch restaurants and bars. You're staying in a historic building that has been magically transformed into a cozy Airbnb retreat. Step Inside the Firehouse Garden with 2 stylish bedrooms that are ready to whisk you away into dreamland, 1 amazing bathroom. With enough space to accommodate up to 6 guests. This is the perfect spot for a getaway with your favorite people.

Hacienda one bedroom with great pool
Heated pool, 8 seat hot tub, outdoor fireplace, and lots of patios to relax. The outdoor kitchen has a pizza oven, bbq, hot water sink, gas stove and oven, smoker and is a perfect place to enjoy. This place is close to restaurants, hiking, lakes and evening fun. Lots of trees: orange, grapefruit, key limes, lemons, pomegranate, figs, dates, grapes and there is a juicer for morning fresh juices. Safe, quiet, and has many hummingbirds and two giant (50 & 80 pound) tortoises.

Private, Convenient Studio Apartment
Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.

Cozy, Private Mid-Century Casita
Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite shows on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. On-site covered parking. Please no pets. This is a no-smoking property (tobacco, weed, vape).

Detached Guesthouse | Driveway Park | Full Kitchen
Enjoy our newly remodeled and professionally designed 1 bed, 1 bath private guesthouse. The stylish and cozy suite includes a full kitchen with brand new appliances, a work space, living room, and bedroom with a closet and ensuite bathroom. It is located just 15 mins away from major destinations, such as ASU, Sky Harbor International Airport, and fun attractions. We offer free parking on the property, in addition to wi-fi, Roku TV and toiletries. We would love to host you!

ASU & Gammage | Private, Yard, Misters
The Studio at Maple Ash is your private retreat in Tempe’s iconic Maple Ash Neighborhood. Thoughtfully designed for ASU visitors, Gammage cast and crew, remote workers, and extended stays. This detached studio offers rare privacy just steps from campus, downtown, and the light rail. Unwind in your private fully enclosed 2,500 sq. ft. yard. Walk to ASU, Gammage Theatre, Mill Ave, and Tempe Beach Park or reach Sky Harbor in just 10 minutes.

Sanitized Spacious Desert Getaway
Newly built guest house in Northeast Mesa. Spacious Living and Kitchen area. 10 foot ceilings. Quite Neighborhood. Right around the corner from Usery Park, Hiking, biking and equestrian trails. Down the road form the Superstition Mountains. 25 minute drive to Saguaro or Canyon Lake. 15 minutes to the Salt River. Quick and easy assess to the Loop 202. Just minutes away from the Superstition Springs Mall.

Mesa Casita with King Bed
Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.

The White Barn @ Freedom Farms
Kick off your boots and relax in this calm, stylish, private guest house on Freedom Farms! Explore the natural swimming pond on the property, venture out to the Sonoran desert for a nature hike, tube down the salt river or mountain bike in Usery! You'll find our location close to the city but not in the city.
Popular amenities for Mesa guesthouse rentals
Family-friendly guest house rentals

Private Guest Studio in the Country

Detached, Private, Clean & Safe Guesthouse with Large Patio

Poolside Casita | Goats & Alpacas | Urban Farm

Private Casita

Private and Quiet - 1 bdrm/1 bath Casita

Boutique Hotel Style Guest House

Beautiful Private Guesthouse on Over 1 Acre!

Our Guest House at Papago Park
Guest house rentals with a patio

Private Pool House & Pool in Phoenix

Granada - Adorable, Chic Studio Apt Biltmore Area

Hidden Oasis at South Mountain!

Scottsdale Casita at Lincoln Rd

Private yard - Short walk to Mill - Historic House

Downtown Studio - Woodland Historic District

PHX's Modern Midtown Carriage House, Free Parking

Beautiful little house
Guest house rentals with a washer and dryer

Centrally Located Renovated Guest House

Beaker Bunker Guest House -Central Phoenix 1BD/1BA

Two Bedroom, Clean Guest House in Gilbert

NEW Stylishly Designed Casita Steps from DTPHX

Gilbert Guesthouse: Centrally Located Cozy Studio

Cozy Guest Home away from Home

1BR Guest House with Private Yard

Unique urban habitat near ASU/downtown Tempe
When is the best time to visit Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ371 | ﺩ.ﺇ419 | ﺩ.ﺇ437 | ﺩ.ﺇ353 | ﺩ.ﺇ323 | ﺩ.ﺇ305 | ﺩ.ﺇ283 | ﺩ.ﺇ275 | ﺩ.ﺇ305 | ﺩ.ﺇ331 | ﺩ.ﺇ364 | ﺩ.ﺇ367 |
| Avg. temp | 14°C | 16°C | 19°C | 23°C | 28°C | 33°C | 35°C | 35°C | 32°C | 25°C | 18°C | 13°C |
Quick stats about guesthouse rentals in Mesa

Total vacation rentals
Explore 150 vacation rentals in Mesa

Nightly prices starting at
Mesa vacation rentals start at ﺩ.ﺇ147 per night before taxes and fees

Verified guest reviews
Over 12,420 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
40 properties feature pools

Rentals with dedicated workspaces
70 properties have a dedicated workspace

Wi-Fi availability
150 of Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesa rentals

4.9 Average rating
Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Mesa's top spots, include Sloan Park, Golfland Sunsplash, and Hohokam Stadium
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- Phoenix Convention Center
- Chase Field
- Lake Pleasant
- TPC Scottsdale - Champions Course
- Grayhawk Golf Club
- Sloan Park
- The Westin Kierland Golf Club
- Tempe Beach Park
- Peoria Sports Complex
- Salt River Fields at Talking Stick
- WestWorld of Scottsdale
- Desert Diamond Arena
- State Farm Stadium
- Grand Canyon University
- Arizona State University
- Surprise Stadium
- Camelback Ranch
- Salt River Tubing
- Goodyear Ballpark
- Scottsdale Stadium
- Papago Park
- We-Ko-Pa Golf Club
- Hurricane Harbor Phoenix
- Trilogy Golf Club at Power Ranch
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