
Guesthouse vacation rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Spacious Casita, Quiet, Peaceful Home - No Stairs!
Cozy Casita in a beautiful, quiet neighborhood. California King bed sleeps two comfortably. 50 inch TV has cable, Netflix, DVD player with assortment of movies. Keurig coffee pot, fridge and microwave. Dining table inside. Outdoor seating opens to peaceful, scenic backyard. Parking available in the driveway. Park to the left of 2 car garage. Our Casita is a modest room that we have done our best to make comfortable for travelers who want an alternative to an impersonal hotel. No pets allowed.

Private yard - Short walk to Mill - Historic House
Reliably operated by a top AZ Superhost with 4,400+ 5 star stays. A TRUE find! Best location in Tempe - walkable to downtown, bars and restaurants on Mill, ASU (1.5 miles), Tempe Beach Park, etc. Hidden-away historic guest house with a private yard (and even a secret outdoor 2nd shower). Professionally designed and setup with guest comfort in mind - everything is here for you - premium bed, a dedicated workstation, fully stocked kitchen, an outdoor seating space with bistro lights. INCLUDED 👇

Entire Private Guest House with King Master
•Location, Location, Location! Extremely safe/social neighborhood just minutes from Oldtown! 5- minute drive by car and 10 minutes by E-scooters! •Bordered by lush greenery, your private backyard/covered patio is a perfect place to enjoy the outdoors •Recently built in 2022 with luxury, comfort, and entertainment in mind ~ you'll love the vibe of your private small backyard and small yet spacious 520sqft space. This guest house has its own private, yet beautiful entrance TPT 21476951 AZ 2026023

Cozy Casita with kitchenette
Bright, comfortable, private room with queen bed, TV, internet, A/C, bath & kitchenette (electric skillet, refrig/freezer, microwave, toaster, Cuisinart coffee maker (single cup or pot), water filter, sink). Add herbs from our courtyard to your stir-fry. Separate casita is located in a small, quiet community near freeways (101, 202). Restaurants & entertainment options nearby in Chandler or Gilbert. Drug store, grocery and fast food all within walking distance (half mile). Community pool.

The Mesa Cottage
The casita was just finished being completely renovated with brand new flooring, paint, appliances, kitchen cabinets, walk-in closet, bathroom, brand new BEDAGA king-size mattress, furnishings, whisper-quiet air conditioner, LED lighting, smooth stucco, and brand new fixtures (updated in January 2021). In addition, the casita has its own washer/dryer for your use only so you can travel light. CableTV, lightning fast WiFi, Amazon FireStick with Netflix are all provided at no extra charge.

Luxury Modern Executive Retreat
Northeast Mesa location close to Tonto National Forest, the Salt River and Saguaro lake. 5 minutes from Boeing, Nammo Talley or MD Helicopter. 25 minutes from downtown Phoenix or Scottsdale. Nestled at the base of the Goldfield mountains. Contemporary open floor plan with modern design. Private entrance and single parking spot in front of the main house. Fast WiFi. Roku and cable TV. Beautiful, quiet neighborhood close to city amenities as well as biking and hiking trails. TPT# 21558238

Cozy, Private Mid-Century Casita
Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite shows on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. On-site covered parking. Please no pets. This is a no-smoking property (tobacco, weed, vape).

Detached Guesthouse | Driveway Park | Full Kitchen
Enjoy our newly remodeled and professionally designed 1 bed, 1 bath private guesthouse. The stylish and cozy suite includes a full kitchen with brand new appliances, a work space, living room, and bedroom with a closet and ensuite bathroom. It is located just 15 mins away from major destinations, such as ASU, Sky Harbor International Airport, and fun attractions. We offer free parking on the property, in addition to wi-fi, Roku TV and toiletries. We would love to host you!

Casita/ Heated Pool, Hot Tub, Amazing Amenities
Private Casita with an amazing steam room and upscale shower. Heated large pool and hot tub along with three covered outbuildings: full outdoor kitchen with BBQ, full stove, MW, Hot Water Sink and large bar area; living room and dining room with wood burning fireplace. A full set of dishes, pots and pans are in this area for your use. Lots of private sitting areas or just hang out in the orchard and pick citrus fruit from the 40 plus trees.

Private Luxury Guesthouse in Mesa
Relax in this calm, stylish space. This guesthouse is the perfect getaway for couples or solo travelers. + King Bed + Sofa Bed + Firepit + Nespresso Machine + 2 Burner Cooktop + Cocktail Shaker Set + Full-Length Mirror + Comfy Robes + Rain Shower Head + Water Softener + Dedicated Parking + Private Entrance 8 min ➡ Downtown Mesa 10 min ➡ Downtown Gilbert 20 min ➡ Sky Harbor Airport 30 min ➡ Central Phoenix @glade.guesthouse

Mesa Casita with King Bed
Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.

The White Barn @ Freedom Farms
Kick off your boots and relax in this calm, stylish, private guest house on Freedom Farms! Explore the natural swimming pond on the property, venture out to the Sonoran desert for a nature hike, tube down the salt river or mountain bike in Usery! You'll find our location close to the city but not in the city.
Popular amenities for Mesa guesthouse rentals
Family-friendly guest house rentals

Best Little Guesthouse in Melrose !

Private Casita

The Oasis Hideout

Sanitized Spacious Desert Getaway

Cozy casita in a beautiful setting

Private studio! Central to popular locations.

Private Detached Tuscan Casita!

Beautiful Private Guesthouse on Over 1 Acre!
Guest house rentals with a patio

Granada - Adorable, Chic Studio Apt Biltmore Area

Ruby's Hideaway, a historic red brick studio.

Private 2BR Midtown Casita + Yard

Hidden Oasis at South Mountain!

Charming & spacious Casita! Like home only better!

PHX's Modern Midtown Carriage House, Free Parking

Lux 1-Bed Casita w/Patio, Laundry+FREE Gtd Parking

Historic Firehouse Downtown Chandler Large shower
Guest house rentals with a washer and dryer

Beaker Bunker Guest House -Central Phoenix 1BD/1BA

NEW Stylishly Designed Casita Steps from DTPHX

Downtown Phx | Private Guesthouse & Parking

Studio B industrial design

Enchanting Ahwatukee Secret Casita

Private and Quiet - 1 bdrm/1 bath Casita

1BR Guest House with Private Yard

La Casita Sereno - Coronado Historic District.
When is the best time to visit Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ371 | ﺩ.ﺇ419 | ﺩ.ﺇ437 | ﺩ.ﺇ353 | ﺩ.ﺇ323 | ﺩ.ﺇ305 | ﺩ.ﺇ283 | ﺩ.ﺇ275 | ﺩ.ﺇ305 | ﺩ.ﺇ331 | ﺩ.ﺇ364 | ﺩ.ﺇ367 |
| Avg. temp | 14°C | 16°C | 19°C | 23°C | 28°C | 33°C | 35°C | 35°C | 32°C | 25°C | 18°C | 13°C |
Quick stats about guesthouse rentals in Mesa

Total vacation rentals
Explore 150 vacation rentals in Mesa

Nightly prices starting at
Mesa vacation rentals start at ﺩ.ﺇ147 per night before taxes and fees

Verified guest reviews
Over 12,420 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
40 properties feature pools

Rentals with dedicated workspaces
70 properties have a dedicated workspace

Wi-Fi availability
150 of Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesa rentals

4.9 Average rating
Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Mesa's top spots, include Sloan Park, Golfland Sunsplash, and Hohokam Stadium
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- Phoenix Convention Center
- Chase Field
- Lake Pleasant
- TPC Scottsdale - Champions Course
- Grayhawk Golf Club
- Tempe Beach Park
- The Westin Kierland Golf Club
- Sloan Park
- WestWorld of Scottsdale
- State Farm Stadium
- Salt River Fields at Talking Stick
- Peoria Sports Complex
- Arizona State University
- Salt River Tubing
- Camelback Ranch
- Surprise Stadium
- Scottsdale Stadium
- We-Ko-Pa Golf Club
- Hurricane Harbor Phoenix
- Goodyear Ballpark
- Papago Park
- Seville Golf & Country Club
- Trilogy Golf Club at Power Ranch
- Desert Diamond Arena
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