
Guesthouse vacation rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Private yard - Short walk to Mill - Historic House
Reliably operated by a top AZ Superhost with 2,250+ 5 star stays. A TRUE find! Best location in Tempe - walkable to downtown, bars and restaurants on Mill, ASU (1.5 miles), Tempe Beach Park, etc. Hidden-away historic guest house with a private yard (and even a secret outdoor shower). Professionally designed and setup with guest comfort in mind - everything is here for you - premium bed, a dedicated workstation, fast speed WiFi, fully stocked kitchen, an outdoor seating space with bistro lights.

Cozy Casita with kitchenette
Bright, comfortable, private room with queen bed, TV, internet, A/C, bath & kitchenette (electric skillet, refrig/freezer, microwave, toaster, Cuisinart coffee maker (single cup or pot), water filter, sink). Add herbs from our courtyard to your stir-fry. Separate casita is located in a small, quiet community near freeways (101, 202). Restaurants & entertainment options nearby in Chandler or Gilbert. Drug store, grocery and fast food all within walking distance (half mile). Community pool.

The Mesa Cottage
The casita was just finished being completely renovated with brand new flooring, paint, appliances, kitchen cabinets, walk-in closet, bathroom, brand new BEDAGA king-size mattress, furnishings, whisper-quiet air conditioner, LED lighting, smooth stucco, and brand new fixtures (updated in January 2021). In addition, the casita has its own washer/dryer for your use only so you can travel light. CableTV, lightning fast WiFi, Amazon FireStick with Netflix are all provided at no extra charge.

Luxury Modern Executive Retreat
Northeast Mesa location close to Tonto National Forest, the Salt River and Saguaro lake. 5 minutes from Boeing, Nammo Talley or MD Helicopter. 25 minutes from downtown Phoenix or Scottsdale. Nestled at the base of the Goldfield mountains. Contemporary open floor plan with modern design. Private entrance and single parking spot in front of the main house. Fast WiFi. Roku and cable TV. Beautiful, quiet neighborhood close to city amenities as well as biking and hiking trails. TPT# 21558238

Private, Convenient Studio Apartment
Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings

Casita/ Heated Pool, Hot Tub, Amazing Amenities
Private Casita with an amazing steam room and upscale shower. Heated large pool and hot tub along with three covered outbuildings: full outdoor kitchen with BBQ, full stove, MW, Hot Water Sink and large bar area; living room and dining room with wood burning fireplace. A full set of dishes, pots and pans are in this area for your use. Lots of private sitting areas or just hang out in the orchard and pick citrus fruit from the 40 plus trees.

Private Luxury Guesthouse in Mesa
Relax in this calm, stylish space. This guesthouse is the perfect getaway for couples or solo travelers. + King Bed + Sofa Bed + Firepit + Nespresso Machine + 2 Burner Cooktop + Cocktail Shaker Set + Full-Length Mirror + Comfy Robes + Rain Shower Head + Water Softener + Dedicated Parking + Private Entrance 8 min ➡ Downtown Mesa 10 min ➡ Downtown Gilbert 20 min ➡ Sky Harbor Airport 30 min ➡ Central Phoenix @glade.guesthouse

Cozy, Private Mid-Century Casita
Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite shows on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. Please, no children or animals.

Sanitized Spacious Desert Getaway
Newly built guest house in Northeast Mesa. Spacious Living and Kitchen area. 10 foot ceilings. Quite Neighborhood. Right around the corner from Usery Park, Hiking, biking and equestrian trails. Down the road form the Superstition Mountains. 25 minute drive to Saguaro or Canyon Lake. 15 minutes to the Salt River. Quick and easy assess to the Loop 202. Just minutes away from the Superstition Springs Mall.

Mesa Casita with King Bed
Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.

The White Barn @ Freedom Farms
Kick off your boots and relax in this calm, stylish, private guest house on Freedom Farms! Explore the natural swimming pond on the property, venture out to the Sonoran desert for a nature hike, tube down the salt river or mountain bike in Usery! You'll find our location close to the city but not in the city.

La Cabra Casita: Poolside Oasis on an Urban Farm
Enjoy an experience unlike any other at our mini ranch in the heart of Chandler. After a day of sunshine in the beautiful Sonoran desert, retreat to your private La Cabra Casita. Relax by the pool, grill up some dinner, feed the goats and alpacas, and in the morning enjoy some fresh duck and chicken eggs.
Popular amenities for Mesa guesthouse rentals
Family-friendly guest house rentals

GORGEOUS Casita in the Heart of Phoenix!

Mid Century Modern Guest House Historic District

Best Little Guesthouse in Melrose !

Scottsdale guest suite

Detached, Private, Clean & Safe Guesthouse with Large Patio

Private Casita

Your favorite PHX guesthouse!

Casita at Sunset Haven Farm
Guest house rentals with a patio

Sunshine Studio! Phx/Scottsdale border!

Ruby's Hideaway, a historic red brick studio.

Charming & spacious Casita! Like home only better!

Spacious Midtown guesthouse with full privacy

Al's Guesthouse at Peoria

Downtown Studio - Woodland Historic District

Zen Modern Casita w/ Private Pool + King Bed

Entire Private Guest House with King Master
Guest house rentals with a washer and dryer

Urban Green House The Garden House

Charming Redbrick Cottage

NEW Stylishly Designed Casita Steps from DTPHX

Private studio! Central to popular locations.

Studio B industrial design

Private and Quiet - 1 bdrm/1 bath Casita

Enchanting Ahwatukee Secret Casita

DARK HOUSE | private, modern Spanish casita
Quick stats about guesthouse rentals in Mesa

Total vacation rentals
Explore 150 vacation rentals in Mesa

Nightly prices starting at
Mesa vacation rentals start at ﺩ.ﺇ110 per night before taxes and fees

Verified guest reviews
Over 12,060 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
40 properties feature pools

Rentals with dedicated workspaces
70 properties have a dedicated workspace

Wi-Fi availability
150 of Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesa rentals

4.9 Average rating
Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Mesa's top spots, include Sloan Park, Golfland Sunsplash, and Hohokam Stadium
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- Lake Pleasant Regional Park
- Chase Field
- Phoenix Convention Center
- Grand Canyon University Championship Golf Course
- TPC Scottsdale - Champions Course
- Salt River Fields at Talking Stick
- Arizona Grand Golf Course
- The Westin Kierland Golf Club
- Salt River Tubing
- WestWorld of Scottsdale
- Grayhawk Golf Club
- Hurricane Harbor Phoenix
- Tempe Beach Park
- Peoria Sports Complex
- Sloan Park
- Dobson Ranch Golf Course
- Ocotillo Golf Club
- Lost Dutchman State Park
- We-Ko-Pa Golf Club
- Seville Golf & Country Club
- Red Mountain Ranch Country Club
- Oasis Water Park
- Trilogy Golf Club at Power Ranch
- Gainey Ranch Golf Club
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