
Guesthouse vacation rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Private yard - Short walk to Mill - Historic House
Reliably operated by a top AZ Superhost with 2,250+ 5 star stays. A TRUE find! Best location in Tempe - walkable to downtown, bars and restaurants on Mill, ASU (1.5 miles), Tempe Beach Park, etc. Hidden-away historic guest house with a private yard (and even a secret outdoor shower). Professionally designed and setup with guest comfort in mind - everything is here for you - premium bed, a dedicated workstation, fast speed WiFi, fully stocked kitchen, an outdoor seating space with bistro lights.

Spacious Casita, Quiet, Peaceful Home - No Stairs!
Cozy Casita in a beautiful, quiet neighborhood. California King bed sleeps two comfortably. 50 inch TV has cable, Netflix, DVD player with assortment of movies. Keurig coffee pot, fridge and microwave. Dining table inside. Outdoor seating opens to peaceful, scenic backyard. Parking available in the driveway. Park to the left of 2 car garage. Our Casita is a modest room that we have done our best to make comfortable for travelers who want an alternative to an impersonal hotel. No pets allowed.

Resort-living in private Studio @ Villa Paradiso
* Private, bright guesthouse immersed in a peaceful oasis of lush landscaping. The guesthouse is right in front of our swimming pool. * Fully remodeled: Kitchen, TV, Wifi, Nespresso & more. * Central location: 10 mins from Old Town Scottsdale, ASU, Sky Harbor Airport, Spring Training & more. Check out my profile for two Luxury B&B suite listings in the main house. Private bedroom & bath, full access to living areas + breakfast. Ask about photoshoots or events across the various property areas.

Luxury Modern Executive Retreat
Northeast Mesa location close to Tonto National Forest, the Salt River and Saguaro lake. 5 minutes from Boeing, Nammo Talley or MD Helicopter. 25 minutes from downtown Phoenix or Scottsdale. Nestled at the base of the Goldfield mountains. Contemporary open floor plan with modern design. Private entrance and single parking spot in front of the main house. Fast WiFi. Roku and cable TV. Beautiful, quiet neighborhood close to city amenities as well as biking and hiking trails. TPT# 21558238

Private studio! Central to popular locations.
Thanks for looking at the Copper State Casita. Our desert chic inspired casita is centrally located and nearby the Arcadia neighborhood. Tucked into an older neighborhood, it’s a 400 square foot studio with its own private patio. All the comforts of home in a small package. A short drive to Airport, Tempe, Scottsdale & Downtown Phoenix. Great for couples, business travel, friends, or small family. Just a few short minutes by car to trails, shopping & many popular restaurants.

Private, Convenient Studio Apartment
Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.

Detached Guesthouse | Driveway Park | Full Kitchen
Enjoy our newly remodeled and professionally designed 1 bed, 1 bath private guesthouse. The stylish and cozy suite includes a full kitchen with brand new appliances, a work space, living room, and bedroom with a closet and ensuite bathroom. It is located just 15 mins away from major destinations, such as ASU, Sky Harbor International Airport, and fun attractions. We offer free parking on the property, in addition to wi-fi, Roku TV and toiletries. We would love to host you!

Casita/ Heated Pool, Hot Tub, Amazing Amenities
Private Casita with an amazing steam room and upscale shower. Heated large pool and hot tub along with three covered outbuildings: full outdoor kitchen with BBQ, full stove, MW, Hot Water Sink and large bar area; living room and dining room with wood burning fireplace. A full set of dishes, pots and pans are in this area for your use. Lots of private sitting areas or just hang out in the orchard and pick citrus fruit from the 40 plus trees.

Entire Suite: Private and Cozy Clark House Casita
Feel right at home by staying at our quaint and unique 350 sq ft casita! Our casita has a full bathroom, and a kitchenette. Catch up on your favorite shows in the living room with our HD smart TV, or watch a movie while cozied up on our comfy queen size bed using the second tv in the bedroom, or relax in the shaded patio surrounded by mature trees. No smoking or vaping inside or outside of the property.

Mesa Casita with King Bed
Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.

The White Barn @ Freedom Farms
Kick off your boots and relax in this calm, stylish, private guest house on Freedom Farms! Explore the natural swimming pond on the property, venture out to the Sonoran desert for a nature hike, tube down the salt river or mountain bike in Usery! You'll find our location close to the city but not in the city.

La Cabra Casita: Poolside Oasis on Urban Farm
Enjoy an experience unlike any other at our mini ranch in the heart of Chandler. After a day of sunshine in the beautiful Sonoran desert, retreat to your private La Cabra Casita. Relax by the pool, grill up some dinner, feed the goats and alpacas, and in the morning enjoy some fresh duck and chicken eggs.
Popular amenities for Mesa guesthouse rentals
Family-friendly guest house rentals

Best Little Guesthouse in Melrose !

Private Guest Studio in the Country

Casita

Detached, Private, Clean & Safe Guesthouse with Large Patio

Urban Green House The Garden House

Sanitized Spacious Desert Getaway

Boutique Hotel Style Guest House

Private Casita w/ Pool* & BBQ in Historic Melrose
Guest house rentals with a patio

Sunshine Studio! Phx/Scottsdale border!

Ruby's Hideaway, a historic red brick studio.

Cozy casita in a beautiful setting

Charming & spacious Casita! Like home only better!

Spacious Midtown guesthouse with full privacy

Your favorite PHX guesthouse!

Zen Modern Casita w/ Private Pool + King Bed

Entire Private Guest House with King Master
Guest house rentals with a washer and dryer

Centrally Located Renovated Guest House

Downtown Phx | Private Guesthouse & Parking

Studio B industrial design

Downtown Studio - Woodland Historic District

Hubbell Hideaway Main House Near Downtown Phoenix

CASA OSCURA | private, modern spanish casita

Cozy Clark Casita

Private Guest House of Queen Creek
When is the best time to visit Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ371 | ﺩ.ﺇ419 | ﺩ.ﺇ437 | ﺩ.ﺇ353 | ﺩ.ﺇ323 | ﺩ.ﺇ305 | ﺩ.ﺇ283 | ﺩ.ﺇ275 | ﺩ.ﺇ305 | ﺩ.ﺇ345 | ﺩ.ﺇ356 | ﺩ.ﺇ349 |
| Avg. temp | 14°C | 16°C | 19°C | 23°C | 28°C | 33°C | 35°C | 35°C | 32°C | 25°C | 18°C | 13°C |
Quick stats about guesthouse rentals in Mesa

Total vacation rentals
Explore 150 vacation rentals in Mesa

Nightly prices starting at
Mesa vacation rentals start at ﺩ.ﺇ110 per night before taxes and fees

Verified guest reviews
Over 12,060 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
40 properties feature pools

Rentals with dedicated workspaces
70 properties have a dedicated workspace

Wi-Fi availability
150 of Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesa rentals

4.9 Average rating
Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Mesa's top spots, include Sloan Park, Golfland Sunsplash, and Hohokam Stadium
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- Lake Pleasant Regional Park
- Phoenix Convention Center
- Chase Field
- Grand Canyon University Championship Golf Course
- Tempe Beach Park
- TPC Scottsdale - Champions Course
- Arizona Grand Golf Course
- The Westin Kierland Golf Club
- Grayhawk Golf Club
- Salt River Fields at Talking Stick
- WestWorld of Scottsdale
- Salt River Tubing
- Peoria Sports Complex
- Sloan Park
- Dobson Ranch Golf Course
- Hurricane Harbor Phoenix
- We-Ko-Pa Golf Club
- Ocotillo Golf Club
- Surprise Stadium
- Seville Golf & Country Club
- Red Mountain Ranch Country Club
- Scottsdale Stadium
- Trilogy Golf Club at Power Ranch
- Papago Park
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