Vacation rentals in Medicine Lake

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Top-rated vacation rentals in Medicine Lake

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Top guest favorite
A modern living area features a yellow couch paired with blue armchairs. A coffee table sits centrally, adorned with decorative items. A wall-mounted television provides entertainment options. Natural light filters through a window, and a large refrigerator is visible in the corner.
Home in Minneapolis
4.94 out of 5 average rating, 105 reviews

Cozy Luxe Hideaway Near West End, Parks & Downtown

Kick back and relax in this calm, stylish space. Here is a transformed newly remodeled luxury basement level home filled with everything you need. The home is nestled in a quiet neighborhood with quick access to the West End shops, trails, parks, fine dining, entertainment, sporting events and all major routes to Minneapolis Downtown and the MSP airport. Hosts live upstairs on the main level but very private, quiet and require no direct interaction with guests, as everything is self-service!

Guest favorite
A modern kitchen is presented with stainless steel appliances and white cabinetry. A central island with two wooden stools invites casual dining. The space is brightened by natural light from nearby windows, creating an open and functional layout, perfect for meal preparation and gatherings.
Home in Minneapolis
4.85 out of 5 average rating, 39 reviews

Remodeled Home, King Beds, FastWIFI, Lake Access

This charming house just outside of Minneapolis offers a soothing retreat for guests. With 3 bedrooms including 2 king beds & 1 queen bed, there's plenty of space for everyone to unwind. This recently remodeled property includes amenities like heating, AC, fast WiFi (1000 MPBS), & a washer/drier for added convenience. Indulge in the luxury of 2 bathrooms featuring shower, bathtub, and hair dryers. Right down the road from wedding venue Hutton House, lots of space & natural lighting to get ready!

Top guest favorite
A spacious living area features a wall of large windows allowing ample natural light and views of surrounding trees. Recycled black slate floors create a seamless look with wooden beams overhead. Comfortable seating arrangements and minimal decor enhance the tranquil atmosphere.
Home in Saint Paul
4.94 out of 5 average rating, 515 reviews

Unique Mid-Century Modern in a Great Neighborhood

Zen retreat in an urban setting; unique mid-century modern meets Japan in a great neighborhood full of architectural gems. Updated 1950's architect-built passive-solar artist retreat house is surrounded by trees and Japanese Gardens. Casual comfort but far from sterile. Complete tranquility 10 min from downtown Mpls and very close to both U of MN campus. Lively, friendly neighborhood in walking distance to grocery store, gift shops, wine shop, yoga studio, coffee shops and great restaurants.

Guest favorite
A modern living space features a light grey sofa with a textured throw and accent pillows beside a round coffee table. A bar height countertop with two stools is visible in the kitchen area, showcasing stainless-steel appliances and a minimalist design.
Apartment in Northeast Minneapolis
4.93 out of 5 average rating, 230 reviews

Modern Minimalist NorthEast Apartment

Make yourself at home in our modern minimalist one bedroom apartment. This cozy ~500 sqft apartment provides all the comfort & has been optimized for functionality! Located in Northeast Minneapolis, you are within walking distance to main metro lines, minutes from downtown, & a short car/bike ride from the UMN. There are tons of restaurants and upscale or dive bars that are full of character. Explore the local experience of the vibrant NorthEast Art District. Book your stay today!

Top guest favorite
A sitting room is depicted with hardwood flooring, featuring a comfortable sofa and two armchairs with patterned upholstery. A small side table holds a lamp, providing soft lighting. Windows are adorned with curtains, allowing natural light to brighten the space.
Apartment in Long Lake
4.9 out of 5 average rating, 161 reviews

Happy Trails

WINTER, We have a circular driveway and a flat driveway. I do my own snow plowing. This is a lovely 640 square foot, mother in law apt on a 5 acres estate, It's very private, quiet and safe with a private entrance. The traffic is light and contact with people is non-existent. Four rooms with a Queen bedroom, A full size pull out sofa in the sitting room, a kitchenette with laundry facilities and a full bath with shower. We are 20 min from downtown Mpls. Off street parking.

Top guest favorite
A cozy dining area features a dark table surrounded by wooden chairs, set on a woven rug. Skylights enhance the space with natural light, while a sectional couch and plush area rug provide a comfortable living area in the background.
Apartment in Northeast Minneapolis
4.96 out of 5 average rating, 241 reviews

Victorian 3rd Floor Studio

Welcome to our charming 3rd-floor studio located within a Victorian home in the heart of the NE Arts district! This cozy retreat boasts an abundance of natural light streaming in through skylights, illuminating a space adorned with beautiful plants, creating a serene and inviting ambiance. This delightful haven features a warm fireplace perfect for cozying up on chilly evenings. Please note, there is some low clearance near the head of the bed and in the bathroom/kitchen area.

Guest favorite
An inviting living space features a brown sofa, a white coffee table, and a patterned area rug. Nearby, a dining table is visible, complemented by large windows that allow natural light to brighten the room. The open layout connects to the kitchen area.
Home in Minneapolis
4.97 out of 5 average rating, 142 reviews

Light & Bright MN Retreat 15 mins from everything

This charming home features 4 bedrooms and 4 beds, and 2 baths. The open floor plan seamlessly connects the living room to the dining area and kitchen, with beautiful flooring, stainless steel appliances, and an impressive stone fireplace. This home provides a warm and welcoming atmosphere with all new furniture. A fenced-in yard with a huge deck perfect for entertaining. The combination of modern amenities and timeless features creates an atmosphere that feels just right!

Top guest favorite
The luxury master bathroom features marble tiled walls, a whirlpool jet tub elevated on a platform, and a glass-enclosed steam shower. Double sinks with sleek design are complemented by modern fixtures. Natural light flows in through multiple windows, enhancing the spacious atmosphere.
Guest suite in Nokomis
4.99 out of 5 average rating, 474 reviews

SpaLike Private Oasis

Spa quality stay in a private-entry, large master suite, minutes from airport and MOA. High end amenities you won't find in most hotels, all to yourself! Relax in a luxury 2 person hot tub & steam shower. Cuddle up in a comfy lounge area! Convenient kitchenette & work space. In the heart of peaceful SE Mnpls, we are blocks away from Lake Nokomis beaches, trails, rentals, unique dining & more. 15 minutes to downtown. Come pamper yourself while you discover Minneapolis!

Guest favorite
Home in Plymouth
4.91 out of 5 average rating, 386 reviews

Blue Cabin

LOCATION: Entire house located off Hwy 169 on the frontage road. Please note the house is right off the highway. My unit is a 650 sq ft house. One bedroom 1 bathroom. Has a full kitchen and laundry free to use. • PROFESSIONALLY CLEANED • EASY ACCESS TO DOWNTOWN (15 MINS) • EASY ACCESS TO AIRPORT & MALL OF AMERICA (30 MINS) • MEDICINE LAKE WALKING PATHS (2 MIN) • FREE COFFEE • FREE PARKING • FREE FAST WIFI • SELF CHECKIN WITH KEYPAD NO SMOKING AND NO PETS PLEASE

Top guest favorite
The spacious living area features polished hardwood floors and a cozy sofa paired with a tufted ottoman. A dining table with chairs is positioned near a kitchenette, which showcases elegant cabinetry and modern appliances. Natural light filters through a window illuminating the room.
Guesthouse in Minnetonka
5 out of 5 average rating, 334 reviews

Minnetonka Carriage House Guest Suite

This is a separate guest suite built with excellence, comfort, and relaxation in mind. It has a separate entry inside the Carriage House. Owner works in and around the hospitality industry and has a goal to make your experience here a great one: great bed and sleep, great shower, great place to work and to relax. In a residential area but close to many great restaurants, retail shops, and services . This is designed for business travelers or couples.

Top guest favorite
A spacious lower-level apartment building is visible, set against a backdrop of freshly fallen snow. The exterior features a combination of gray and white tones, with multiple windows and a large porch area. Nearby trees and neighboring homes add to the scenic winter landscape.
Guest suite in Lowry Hill
4.92 out of 5 average rating, 227 reviews

Stroll to Lakes from Stylish Garden Apartment

Cozy, sunny, lower-level apartment. Top-tier neighborhood of historic mansions, great for walking, biking, running. Fully-equipped kitchenette with granite countertops, dishwasher, and stainless steel appliances. Dedicated workspace and top-speed wifi. Extra room can serve as private 2nd bedroom with sofa bed pulled out. Shared laundry room but otherwise the place is yours alone with your own entrance. Note: this is a walkout basement apartment.

Guest favorite
The exterior of the tiny house features a modern design with a blue steel facade. A welcoming front porch is framed by vibrant flowers and plants, with two teal chairs positioned for relaxation. A pathway leads toward the entrance, surrounded by well-maintained landscaping.
Guesthouse in Hiawatha
4.96 out of 5 average rating, 1,036 reviews

Tiny House Peaceful and Private

New 2017 built Tiny House perfect for travelers. Close to light rail. Comes with original poetry. New finishes include W/D, full kitchen, 3/4 bath w/large shower, A/C, fast WiFi internet, desk. Queen size bed and convertible couch will accommodate three adults. Quiet family friendly south Minneapolis location with less than 10 min walk to light rail easily connected to downtown and the airport. High chair and pack and play available upon request.

Popular amenities for Medicine Lake vacation rentals