
Vacation rentals in Rochester
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Rochester
Guests agree: these stays are highly rated for location, cleanliness, and more.

Relaxation Station 0.7 Miles from Mayo King Bed
Your home away from home awaits! With 3 bedrooms, 1 bath, kitchen, living room, office space, and laundry room (all newly renovated), this home is perfect for you! A large backyard and patio, easy access to miles of walking trails and a park right across the street makes this home great for relaxing outdoors. Conveniently located 0.7 miles from downtown and Mayo makes it a perfect stay for guests visiting the clinic or other Rochester events. We look forward to warmly welcoming you to Rochester!

Woodland Retreat, Full private walkout lower level
Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

Euro House, Bright! Near Mayo-Single Family Home
Welcome to your home away from home! This private, single-family home was thoughtfully designed and is located in a quiet area just 5 minutes (0.9 miles) from the Mayo Clinic. Step into a master gardener’s dream—a beautifully landscaped yard filled with native plants and outdoor seating, perfect for relaxing after a long day. 2 Queen Bedrooms, 2 Full Bathrooms, modern finishes throughout, Super clean and pet-free. Off-street parking, Washer & dryer, Wi-Fi, Smart TVs & Fully stocked kitchen.

Home for the Traveler, a walk to St. Mary's
This place is located near the heart of Rochester, within blocks of St. Mary's hospital, very peaceful, cozy and private. A lower-level unit in an older home, plenty of windows and light, and includes a gorgeous bedroom with a fireplace, a full kitchen, a reading room, and a clean, updated bathroom. This home is also close to the Apache mall, the Canadian Honker and other local restaurants, coffee shops, and the walking/biking trail system. There is also Wi-Fi, laundry, and parking on-site.

The Little House | 1 mi from downtown, Love Pets!
The Little House is the perfect place of you're looking for something Cozy, stylish, and close to everything that you need. This home was a fun renovation project for my husband and I. It's located in the family friendly Sunnyside Addition neighborhood and we've worked hard to make sure you have everything you need during your stay. This home has a beautiful fully fenced in yard with a neighborhood feel while still being less than a 5 minute drive from Downtown & Mayo Clinic Campuses!

Mayo Downtown's Prairie Home Retreat
Nestled in a serene corner, this home offers a perfect blend of tranquility and accessibility; being near the Mayo campus and Rochester's key attractions. Enjoy comfortable beds, a well-appointed kitchen, and a fenced yard with patio gardens. It's an excellent spot for family bonding, featuring three smart TVs, rapid Wi-Fi, and a variety of indoor and outdoor entertainment options. We strive to accommodate flexible check-in/check-out arrangements whenever feasible. Rollator accessible.

NEW: Calming main floor retreat near Mayo Clinic
• Enhanced cleaning protocols due to COVID • Fully renovated apartment in winter 2019 • Main floor apt in quiet 4plex • 550 square feet with refinished hardwood floors throughout • La-Z-Boy power recline loveseat with power headrests and USB ports. Both sides also rock. • 65" Smart TV with DirecTV • Free off-street parking • 6 blocks north of Mayo Clinic • Walk-in shower • Queen bed • Full kitchen with gas stove and dishwasher • High-speed WiFI — 100+ MBPS • Shared laundry in basement

Restful sanctuary close to Mayo Clinic
This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

Spacious Modern Home Near Mayo, St. Mary's Campus
- 5 min walk to Mayo Clinic, St. Mary’s campus - 3 bedrooms, 3 bathrooms, and a loft - unique design with vaulted ceiling and skylights in the style of Frank Lloyd Wright, one of its kind in the whole neighborhood - two-car garage + another dedicated parking space outside - walkable and safe family-friendly neighborhood close to downtown and all amenities - outside front and back patios - fusball play table - dedicated workspace - high speed wifi - Apple TVs - washer and dryer

The Guesthouse Cottage, walkable to Mayo Clinic
Our Guesthouse has a clean cottage feel. The king and queen bedrooms offer closets and quality linens. Cook meals in a fully stocked kitchen. Book an Uber, or walk 0.6 miles to Mayo's main Gonda building. We're close to grocers, coffee, parks and trails, and downtown's restaurants, shops, and a lovely public library. Free washer and dryer on site. Google TV and internet. 3-season porch. Small guest garage. No smoking on the property.

Cozy home next to Mayo Clinic & historic parks!
Cozy single level 2 bedroom, 1 bath. Fully furnished kitchen with TV, WiFi, and smart lock. It’s a 1.6 miles to Mayo Clinic. Walking distance to Historic Quarry Hill Park and Silver Lake Park. City bus line to Mayo Clinic 1/2 block away. Newly remodeled bathroom with full linen and toiletries. Quiet neighborhood, with full driveway parking. We also have a baby gate for the stairs. Enjoy your next home away from home !

Cedar Loft is a tranquil retreat
If you are looking for a quiet retreat w/private entrance outside the city, you are home. Trees are outside every window with palpable serenity yet is still an easy ten-minute drive to downtown Rochester. This is a family-friendly place with crib and changing table. This is not a party house. It has a kitchenette so we will provide information to restaurants and grocery stores within 5 minutes.
Popular amenities for Rochester vacation rentals
Other great vacation rentals in Rochester

Tranquil 2Bed/2Bath w/Balcony near Mayo

Best of Country Living in the City!

Remodeled 1 bedroom house - Close to Mayo Clinic

New! MN Comforts The Heart 4Bd/2Bth, 12min to Mayo

Kaleidoscope Flat 1 bd 1 mi to Mayo, Free Parking

Luxury Cottage | 5 Blocks from Mayo | No Stairs!

The Don

Unit 2365J | 2bd/2bth | Single-Family Home
Quick stats about vacation rentals in Rochester
Total rentals
670 properties
Nightly prices starting at
ﺩ.ﺇ73 before taxes and fees
Total number of reviews
33K reviews
Family-friendly rentals
440 properties are a good fit for families
Pet-friendly rentals
220 properties allow pets
Rentals with a pool
30 properties have a pool
Your guide to Rochester
All About Rochester
Located amid tree-topped bluffs in southeastern Minnesota, the city of Rochester lies in the valley of the Zumbro River. The river, which winds its way downtown, provides opportunities for kayakers and tubers to float down the waterway. Rochester is Minnesota’s third-largest city and home to one of the country’s best-known medical facilities, which has fed the city’s growth, but it manages to keep a small-town vibe with a walkable downtown.
During the warmer months, musical concerts and other artistic performances take place by the riverside, and you can hop on one of the city trolleys to check out a wine trail, a local brewery, or the farmers’ market. The Twin Cities are a little over an hour north, while the Mississippi River’s Bluff and Amish Country are within an hour’s reach.
A well-developed park system around the city offers more than 85 miles of multi-use trails to explore. Near the heart of downtown, the Quarry Hill Nature Center features trails and paved pathways for hikers and bikers. The area was underwater during prehistoric times, and you may find fossils and other remnants if you keep your eyes out for them. During the wintertime, you can rent snowshoes and cross-country skis at the quarry.
The best time to stay in a vacation rental in Rochester
The best time to stay in one of Rochester’s vacation rentals is during early summer, when temperatures are typically pleasant. July and August are warm to hot and more humid, but you can cool off by paddling on one of the nearby lakes and rivers. In September and October, temperatures cool down, and the nights grow chilly. Apple orchards and changing fall foliage are main attractions, as are the pumpkin patches and bonfires.
Snowfall often begins in October and lasts through April, and Minnesota winters are snowy, icy, and cold. The Christmas holiday season kicks off in November with the Festival of Trees, and skating rinks like the outdoor skating rink at Soldiers Field are a popular place to be — next to a fireplace is nice, too. January and February temperatures stay below freezing, and the wind chill factor can keep temperatures at zero degrees Fahrenheit. But there’s little chance of cabin fever with themed ice bars, ice sculptors, DJs, and bright lights of the SocialICE festival. March weather can still have freezing temperatures, but the winter thaw usually begins by April.
Top things to do in Rochester
Lanesboro and Amish Country
A 60-minute drive southeast of Rochester lands you in Lanesboro, an artistic community home to theater troupes, musicians, and visual artists. You’ll also find several antique shops and independent boutiques. Nearby Harmony is home to a thriving Amish community, and local stores sell Amish handcrafted furniture, baskets, quilts, and leather goods.
Root River and Root River Trail
Within an hour east of Rochester is the Mississippi River’s Bluff Country. You can glide in a canoe down the 80-mile Root River or bike the Root River Trail, whose path runs for 42 miles along a disused railway line. There are 30 miles of blacktop for biking in the warmer months and for cross-country skiing in winter.
Silver Lake Park
Just 10 minutes from the center of Rochester, you can fish, rent a paddleboat, or cruise with a friend on a tandem bike around Silver Lake. Rental bikes and strollers are available. Around the 1.8-mile loop are picnic areas, an outdoor pool, and a skate park.
Frequently Asked Questions
Where should I stay in Rochester?
Make yourself at home in Rochester by choosing from our most frequently booked neighborhoods. We have over 370 vacation rentals in Kutzky, over 600 vacation rentals in Hawthorne, and over 600 vacation rentals in Downtown Rochester.
Are there vacation rentals with a dedicated workspace in Rochester?
Yes! Work meets play with ease at over 450 vacation rentals in Rochester featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there pet-friendly vacation rentals in Rochester?
Four-legged friends are welcome in Rochester. Choose from more than 190 vacation rentals for guests traveling with pets.
Are there Rochester vacation rentals on Airbnb with pools?
Yes! Dive into the perfect getaway at one of over 20 vacation homes with pools in Rochester, available on Airbnb. Make a splash and soak up the sun in style!
How much does it cost to stay in apartment rentals in Rochester?
Experience the best of Rochester with our apartment rentals, starting at about $20 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do house rentals in Rochester have self check-in?
Absolutely! We offer over 160 house rentals with self check-in in Rochester. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Rochester have a gym?
Absolutely! We offer over 40 house rentals with a gym in Rochester. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Rochester have a bbq area?
Absolutely! We offer over 70 house rentals with a bbq area in Rochester. Enjoy a tailored experience with all the comforts you desire.
Do townhouse rentals in Rochester have wifi?
Absolutely! We offer over 20 townhouse rentals with wifi in Rochester. Enjoy a tailored experience with all the comforts you desire.
Are there family-friendly vacation rentals in Rochester?
Rochester has more than 430 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.
Destinations to explore
- Chicago Vacation rentals
- Downtown Chicago Vacation rentals
- Minneapolis Vacation rentals
- Platteville Vacation rentals
- Milwaukee Vacation rentals
- Omaha Vacation rentals
- Wisconsin River Vacation rentals
- Lake Geneva Vacation rentals
- Madison Vacation rentals
- Wisconsin Dells Vacation rentals
- Duluth Vacation rentals
- Twin Cities Vacation rentals
- Rentals with a washer and dryer Rochester
- Fitness-friendly rentals Rochester
- Rentals with pools Rochester
- Hotel rentals Rochester
- Rentals with a patio Rochester
- Rentals with an EV charger Rochester
- Pet-friendly rentals Rochester
- Apartment rentals Rochester
- Rentals with breakfast Rochester
- Condo rentals Rochester
- House rentals Rochester
- Rentals with a fire pit Rochester
- Rentals with outdoor seating Rochester
- Rentals with a fireplace Rochester
- Treasure Island Resort & Casino
- Whitewater State Park
- Perrot State Park
- River Springs Water Park
- Red Wing Water Park
- coffee mill ski area
- Faribault Family Aquatic Center
- Four Daughters Vineyard & Winery
- Salem Glen Winery
- Maiden Rock Winery & Cidery
- Villa Bellezza
- welch village
- Garvin Heights Vineyards
- Falconer Vineyards
- Whitewater Wines Llc