Apartment vacation rentals in Rochester

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

Family · Value · Hiking

Extended Stay Suite Near Mayo Clinic

Stay comfortably in Rochester with all the conveniences of home. Whether you're visiting Mayo Clinic, traveling for work, relocating, or simply exploring the area, this bright and modern furnished suite offers everything needed for a stress-free stay. Enjoy a living space filled with natural light, fully equipped kitchen with full-size appliances, and an in-suite washer and dryer. WiFi, comfortable furnishings, and thoughtful spaces make this suite ideal for both short visits and extended stays.

Location · Check-in · Quiet

Large 1 BR in 4plex, 1 mile from Mayo.

Spacious, quiet 1 BR unit (583 sq. ft.)with all of the essentials and room to relax. The apartment has a living room with a smart TV, kitchen with a dining area, bedroom with a full size bed, office/den area, bathroom with a tub and shower with a dressing area. The kitchen has all of the necessities to make your own meals and there are plenty of extra linens for guests. This is an older home so the hardwood floors creak a little and it has hot water heat. There is free parking behind the house.

Family · Value · Checkout

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in NW Rochester. Easy access to highways, grocery store, coffee shop/cafes, Target, and walking trail. Completely furnished with linens, Netflix and Hulu, Wi-fi, and coffee maker. The laundry is shared with the host; who resides in the upper level. Please, no large construction vehicles. Truly a home away from home!

Location · Family · Biking

Modern Comfort Stay | 2BR | Close to Mayo

Comfortable, modern 2BR lower-level unit just 5 minutes from Mayo Clinic perfect for patients, families, and traveling professionals. Enjoy a cozy living room with Smart TV, two private bedrooms, a walk-in shower, and in-unit washer/dryer. No stairs, easy access, with a bus stop right nearby. Fast WiFi included. Easy street parking right by your private entrance. Located in a quiet residential area with quick access to shops and dining. Note: duplex with tenants upstairs; light noise possible.

Value · Location · Decor

Lux 1 BR I 1 Block to Mayo Skyway I Parking I Pets

Welcome to your luxury refined home base in the heart of downtown Rochester. Located at The Maven on Broadway, this upscale one-bedroom apartment offers the perfect blend of comfort, convenience, and elevated living—just a short walk to the skyway connecting you in minutes to the Mayo Clinic System. Whether you’re here for medical care, professional work, or supporting a loved one, this thoughtfully designed space provides a calm, stylish space with all the amenities needed during your stay.

Location · Value · Pets

|Rochester S-E Gem| Airbnb August Deal!

Welcome to our privately owned - home base Airbnb unit in the heart of Rochester, MN where comfort meets unbeatable charm and convenience! What can you expect? Very CLEAN and modified unit that meets all your expectations, perfectly located less than a mile from the Mayo Clinic! This amazing place is just a quick 5-min drive (or an easy 20-minute walk) to the Mayo Clinic, making it an ideal stay for medical travelers, medical professionals, or a day out and about near the HEART of Rochester!

Value · Location · Indoor spaces

Summer Special-2 Bedroom Close to Mayo Clinic

Peaceful and centrally located cottage. This home is a beautifully furnished main-level triplex just 5 minutes from Mayo Clinic. Bus stop on property and multiple restaurants 3 minutes away. This 2-bedroom, 1-bath unit has everything you might need to recover from a surgery, to feel at home while seeking treatment or to enjoy beautiful Rochester. The house is child friendly with a nice selection of toys and books to keep the little ones occupied. Pets welcome at a charge of $50/pet/month.

Family · Value · Indoor spaces

Skyway connected Extended Stay in Rochester

With direct skyway access, Broadway Plaza is steps from Mayo Clinic. Apartments at Broadway Plaza feature spacious layouts with in-unit laundry, en-suite bathrooms, a half bath, and full kitchens. On-site indoor pool and gym offer places to unwind. Weekly housekeeping provides privacy and comfort. Note: Upon check-in, our front desk will capture a card and IDs for every adult to keep on file. A $500 security deposit will be taken for stays over 8 nights and returned if there are no damages.

Location · Family · Quiet

Cozy Clinic Retreat

Fully remodeled 1 bedroom, 1 bath unit with an office offering comfort and flexibility. The modern kitchen features quartz countertops while the bright living room is perfect for relaxing, watching TV, or playing board games. The bathroom includes a tub and tiled shower, and the bedroom offers a large closet. The office has a desk and chair, plus an air mattress for a third guest. Two driveway parking spaces included. Located four blocks from Mayo Clinic and just steps from the bus line.

Location · Decor · Check-in

All you need! Close to Mayo/Downtown/Fairgrounds.

Come stay at The Crane! This is a bright and clean space newly renovated for you. It's less than 2 miles from Mayo Clinic and downtown Rochester, and 2.4 miles to St. Mary's Hospital. It's close to shopping, restaurants, and within walking distance to the Fairgrounds/Graham Arena. The apartment is stocked with everything you need to feel right at home, including a full kitchen, memory foam mattress toppers, Roku TVs for your streaming services, and high-speed Wi-Fi. Book your stay today!

Location · Value · TV

The Gwen | 2BR Apt, Fenced Yard, Pets, <3mi Mayo

A fully furnished 2-bed, 1.5-bath upstairs apartment with its own attached fenced yard and patio — a favorite for guests traveling with a dog. Full kitchen, dining area, living room, and a dedicated workspace for remote work. Free parking, quiet neighborhood feel, under 3 mi from Mayo and downtown. • 2 BR / 2 beds / 1.5 baths · sleeps 4 • Fenced yard + patio · workspace • Pet-friendly · free parking • Under 3 mi to Mayo Want the whole building? Book "Century Noll" for both units.

Family · Location · Comfort