
Apartment vacation rentals in Rochester
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Top-rated apartment rentals in Rochester
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Oasis Luxe Suite—Steps from Mayo Clinic Hospital
This luxury suite is a private wing on the lower level of a newly renovated 4-level mansion. Conveniently located in one of the trendiest neighborhoods in Rochester. Steps from the Mayo Clinic St. Marys hospital, Starbucks & Caribou coffee, restaurants, grocery stores, nightlife & downtown. FEATURES High speed internet 55” HD LED TV Workspace High-end interior Queen size beds Washer/dryer Fully stocked kitchen Free garage parking Keyless entry Super convenient for short-term & long-term stays.

Woodland Retreat, Full private walkout lower level
Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

Relaxing, main floor apartment in 4plex, #2.
This is a quiet main floor apartment (491 sq. ft.) in a 4-plex located 1 mile from Mayo. It has a all of the cooking necessities needed to make your own meals. There is a full size bed in the bedroom. This unit is in an older house with radiator heat and a big front porch. The floors are squeaky in a few places. Since it is a 4plex you will hear some sounds from other guests but it is generally quiet. There is parking behind the house and a washer and dryer in the basement available to guests.

Lux 1 BR I 1 Block to Mayo Skyway I Parking I Pets
Welcome to your luxury refined home base in the heart of downtown Rochester. Located at The Maven on Broadway, this upscale one-bedroom apartment offers the perfect blend of comfort, convenience, and elevated living—just a short walk to the skyway connecting you in minutes to the Mayo Clinic System. Whether you’re here for medical care, professional work, or supporting a loved one, this thoughtfully designed space provides a calm, stylish space with all the amenities needed during your stay.

Discount Charming 2 Bedroom Close to Mayo
Peaceful and centrally located cottage. This home is a beautifully furnished main-level triplex just 5 minutes from Mayo Clinic. Bus stop on property and multiple restaurants 3 minutes away. This 2-bedroom, 1-bath unit has everything you might need to recover from a surgery, to feel at home while seeking treatment or to enjoy beautiful Rochester. The house is child friendly with a nice selection of toys and books to keep the little ones occupied. Pets welcome at a charge of $50/pet/month.

Home for the Traveler, a walk to St. Mary's
This place is located near the heart of Rochester, within blocks of St. Mary's hospital, very peaceful, cozy and private. A lower-level unit in an older home, plenty of windows and light, and includes a gorgeous bedroom with a fireplace, a full kitchen, a reading room, and a clean, updated bathroom. This home is also close to the Apache mall, the Canadian Honker and other local restaurants, coffee shops, and the walking/biking trail system. There is also Wi-Fi, laundry, and parking on-site.

Rochester Home (Duplex) 5 min walk to Mayo
This home is located in the heart of the historic Rochester, MN. Just a stones throw from the Mayo Clinic. This downtown area is packed with shops and eating establishments, all interconnected via the walking subway system, for those cold winter days. When the weather warms, beautiful parks and paths abound in an endless display of green natural space. If you find yourself here in the summer you are welcome to my organic garden. I hope your travels are safe and look forward to meeting you.

Step to Mayo Clinic | Free Parking | Private Unit
Welcome to our cozy home in Rochester’s historic Southwest neighborhood! We’re right across from the Mayo Clinic Downtown Campus and just four blocks from St. Mary’s Hospital—perfect for Mayo patients, visitors, or staff. This main-floor, two-bedroom unit features WiFi, FuboTV, a smart lock, and free use of a washer and dryer. Free parking is included, with space for a camper if arranged in advance. The area is quiet, safe, and mostly home to medical professionals. We’d love to host you!

All you need! Close to Mayo/Downtown/Fairgrounds.
Come stay at The Crane! This is a bright and clean space newly renovated for you. It's less than 2 miles from Mayo Clinic and downtown Rochester, and 2.4 miles to St. Mary's Hospital. It's close to shopping, restaurants, and within walking distance to the Fairgrounds/Graham Arena. The apartment is stocked with everything you need to feel right at home, including a full kitchen, memory foam mattress toppers, Roku TVs for your streaming services, and high-speed Wi-Fi. Book your stay today!

Restful sanctuary close to Mayo Clinic
This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

SALE: Remodeled retreat near Mayo Clinic
• Enhanced cleaning protocols due to COVID • Fully renovated apartment in summer 2018 • Brand new kitchen in March 2026 • 650 square feet • Upstairs apartment in quiet 4plex • Free off-street parking • 5 blocks north of Mayo Clinic • Walk-in tiled shower • Queen bed • Oversized power recline La-Z-Boy chair • Reclining leather loveseat • 43" Smart TV with DirecTV/cable • High-speed WiFI — 300 MBPS • Shared laundry in the basement • Huge windows for tons of natural light

Apt A ! Close to Dn town and mayo clinic and Gonda
Apt A ! only 5 minit s from Mayo clinic and Gonda ! Main lower level 1 queen sized bedroom 1 single bedroom can sleep 3 guests but thats with 2 people in the queen bed and 1 in the twin bed but if your party can not share beds then sum one will have to use the couch ? living space set up for housekeeping 9 block s from mayo clinic n down town shop s and fine dining !
Popular amenities for Rochester apartment rentals
Weekly apartment rentals

Tranquil 2Bed/2Bath w/Balcony near Mayo

Peaceful Riverfront 2Bed/2Bath w/Balcony near Mayo

Beautiful Duplex home 5 minute walk to Mayo Clinic

NEW: Calming main floor retreat near Mayo Clinic

Cozy, comfy 1 BR unit in triplex, 4 blocks to Mayo

Spacious 2Bed/2.5Bath W/Rooftop Deck Near Mayo

Large 1 BR in 4plex, 1 mile from Mayo.

The Travelers Flat, a walk to St. Mary’s
Private apartment rentals

8076-WALK to Mayo-Charming Studio Apt Free Parking

The Cozy Classic

EXCEPTIONAL, CONTEMPORARY 2BD/1 BA/ CLOSE TO MAYO

One bedroom Apt walk to Mayo and St,Mary's.

Luxury 1 bedroom Serenity

Luxury updated two bedroom apt

Fresh space near Mayo Clinic and downtown

Cozy Clinic Retreat
Family-friendly apartment rentals

Remodeled 2nd-floor apartment blocks from Mayo

St. Mary's Retreat

Curated Classic a block from St. Mary's Hospital

Calm & Comfort | 12 Min to Mayo

Clean, cozy, close to Mayo & Fairgrounds.

Cozy, Private Studio. Near Mayo/Downtown/Parks

Penthouse Suite—Steps from Mayo Clinic Hospital

Luxury King Suite—Steps from Mayo Clinic Hospital
When is the best time to visit Rochester?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ242 | ﺩ.ﺇ253 | ﺩ.ﺇ246 | ﺩ.ﺇ261 | ﺩ.ﺇ279 | ﺩ.ﺇ294 | ﺩ.ﺇ301 | ﺩ.ﺇ294 | ﺩ.ﺇ275 | ﺩ.ﺇ275 | ﺩ.ﺇ268 | ﺩ.ﺇ253 |
| Avg. temp | -10°C | -7°C | 0°C | 7°C | 14°C | 20°C | 21°C | 20°C | 16°C | 9°C | 1°C | -6°C |
Quick stats about apartment rentals in Rochester

Total vacation rentals
Explore 130 vacation rentals in Rochester

Nightly prices starting at
Rochester vacation rentals start at ﺩ.ﺇ73 per night before taxes and fees

Verified guest reviews
Over 6,130 verified reviews to help you choose

Family-friendly vacation rentals
60 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 50 rentals that welcome pets

Rentals with dedicated workspaces
90 properties have a dedicated workspace

Wi-Fi availability
130 of Rochester vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Rochester rentals

4.8 Average rating
Rochester stays are highly rated by guests—averaging 4.8 out of 5!
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