Apartment vacation rentals in Rochester

A spacious living area features warm wood floors and sloped ceilings. A gray couch and a striped accent chair provide seating, complemented by a coffee table and a woven basket. A dining area with a table and chairs is visible in the background, leading to the kitchen.

4.99 out of 5 average rating, 81 reviews

Kaleidoscope Flat 1 bd 1 mi to Mayo, Free Parking

Kaleidoscope Flat: This unique one bedroom has a style all its own! Enjoy beautiful wood floors, modern kitchen and bath with walk-in shower. Private entrance to a newly renovated second floor unit. The king bed has a memory foam mattress with adjustable bed frame for enhanced comfort and healing. Couch with pull-out full-size mattress. Child's pack and play available upon request. Private laundry in unit. Street parking in front. Free pass for Mayo clinic parking ramps. This saves $12 daily! 🙂

Guest favorite

The modern living area features a comfortable blue sofa adorned with a patterned throw. Two orange accent chairs complement a coffee table at the center. A large wall-mounted TV is visible, while soft lighting creates an inviting atmosphere. The open-concept space connects to the kitchen area.

5 out of 5 average rating, 15 reviews

Penthouse Suite—Steps from Mayo Clinic Hospital

This luxury suite is a private wing on the 3rd floor of a newly renovated 3-story mansion. Conveniently located in one of the trendiest neighborhoods in Rochester. Steps from the Mayo Clinic St. Mary's hospital, Starbucks & Caribou coffee, restaurants, grocery stores, nightlife & downtown. FEATURES High speed internet 75” HD LED TV Workspace High-end interior King size beds Washer/dryer Fully stocked kitchen Free garage parking Keyless entry Super convenient for short-term or long-term stays.

A garden-level apartment is accessed via a gravel driveway that leads to a charming home. Lush greenery surrounds the path, and the structure features a mix of siding colors, with large windows framed by blue shutters, creating an inviting exterior appearance.

4.93 out of 5 average rating, 176 reviews

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

A well-appointed living area is highlighted by a brown couch adorned with decorative pillows. A mid-century modern coffee table is center stage on a patterned rug. Natural light fills the space through two large windows, and a blue accent chair adds a pop of color.

4.86 out of 5 average rating, 29 reviews

Fresh space near Mayo Clinic and downtown

Minutes away from downtown shops, restaurants, and Mayo Clinic, this main-level apartment is newly-renovated, cheerful, and ready for your arrival. The open living/dining area feels spacious and bright, with two picture windows letting in lots of natural light. Enjoy two private bedrooms, each with a queen-sized bed. Fully-equipped kitchen makes for efficient cooking and baking. Bus stop less than a block away. Trails nearby. From May-Oct, visit the local Farmer's Market at Graham Park.

A cozy bedroom features a wooden bed frame with a light comforter and pillows. Nightstands with lamps are positioned on either side, providing soft lighting. A dresser sits against the wall, complemented by a decorative plant and an art piece. Natural light is softly diffused through the window curtains.

4.96 out of 5 average rating, 47 reviews

The Nest on Broadway

Welcome to The Nest on Broadway. This quiet one bedroom apartment is situated on North Broadway, just a few blocks from downtown Rochester, with a free dedicated parking space and private entry on the back of the building. The door is also just steps away from the bus stop. This cozy abode features a classic retro style, queen bed, free wifi, and a dedicated workspace. Restaurants, Silver Lake, and other amenities are in close walking distance. You'll feel right at home settling into The Nest.

An outdoor plaza is presented with a red canopy covering a seating area for dining. Surrounding the area are modern buildings, and decorative planters. The pavement is smooth, creating an accessible path, with grassy patches visible in the foreground.

4.92 out of 5 average rating, 121 reviews

Walking Distance To Mayo!

Enjoy the convenience of staying closer to the Clinic than most Mayo employees can park! The subway to Mayo is literally right down your street. This is a bottom floor apartment so no climbing a ton of stairs. This is a perfect place for those who value privacy and convenience. There is no hassle of a lobby or figuring out where to go, just open the main door and your apartment is right there! Self check in is super easy giving you immediate access to drop your bags and relax from your trip.

A cozy bedroom features a spacious bed with neatly arranged pillows and a navy throw blanket. Two lamps illuminate the nightstands flanking the bed. Wall art and a large mirror enhance the inviting atmosphere, while natural light filters in through nearby windows.

4.93 out of 5 average rating, 164 reviews

Home for the Traveler, a walk to St. Mary's

This place is located near the heart of Rochester, within blocks of St. Mary's hospital, very peaceful, cozy and private. A lower-level unit in an older home, plenty of windows and light, and includes a gorgeous bedroom with a fireplace, a full kitchen, a reading room, and a clean, updated bathroom. This home is also close to the Apache mall, the Canadian Honker and other local restaurants, coffee shops, and the walking/biking trail system. There is also Wi-Fi, laundry, and parking on-site.

Guest favorite

The entrance to Nicholas Apartments is marked by a welcoming archway. Lush greenery and neatly manicured lawns surround the pathway, which leads to the inviting brick building featuring multiple balconies and large windows.

4.88 out of 5 average rating, 17 reviews

Free Parking, New Apartment, Steps From Mayo!

Step into a serene retreat with this beautifully designed 1-bedroom apartment. Combining sleek modern design with cozy comfort, this space is a perfect blend of style and functionality. The apartment features a luxurious king-sized bed, a fully equipped kitchen, and a relaxing living area, all thoughtfully crafted to ensure your stay is as comfortable as it is convenient. Whether you're here for a short visit or an extended stay, this unit offers a peaceful haven in the heart of the city.

A cozy living area is presented with a brown sofa adorned with two textured pillows. A dark chair complements a wooden coffee table, which holds a small potted plant. Light grey carpet and subtle wall art enhance the calm aesthetic of the space.

4.8 out of 5 average rating, 5 reviews

Dreamy Den | Right Across From St Marys!+Parking

Discover a cozy retreat located right across from the Mayo Clinic’s Saint Mary’s campus. This inviting unit features a warm atmosphere, perfect for unwinding after a busy day. With a variety of restaurants and coffee shops just a short stroll away, you'll have everything you need within easy reach. Whether you're in town for medical appointments or exploring Rochester, this charming space offers the perfect blend of comfort and convenience for an enjoyable stay. Your ideal getaway awaits!

Guest favorite

A living area features comfortable seating with a recliner and a neutral-toned couch. Light streams through sheer curtains, illuminating a decorative coffee table on an area rug. A desk with a lamp is positioned against the wall, providing a functional workspace.

4.81 out of 5 average rating, 26 reviews

Discounted 5-Star Duplex 5 Mins to Mayo 2 Bedroom!

Are you ready for a fantastic stay in a well-appointed 2-bedroom 1 bath lower-level duplex 5 minutes to Mayo Clinic? This unit is freshly remodeled, beautifully furnished and very convenient. You will find everything you might need to recover from a surgery or to feel at home while seeking treatment. The house is child friendly with a nice selection of toys and books to keep the little ones occupied. Pack-n-Play and highchair are available. Pets are welcome with a charge of $50/pet.

A cozy living room space features a beige couch adorned with decorative pillows and a low coffee table. The white brick wall serves as a backdrop for a fireplace, which is framed by a wooden mantle decorated with artwork and a wreath. Natural light enters through a window.

4.97 out of 5 average rating, 246 reviews

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

An open-concept living area is highlighted by a sleek kitchen with stainless steel appliances and a spacious island. Comfortable seating includes a blue leather couch and modern stools at the breakfast bar. Natural light fills the space through large windows, enhancing the relaxed atmosphere.