House vacation rentals in Edisto River

Find and book unique houses on Airbnb

Top-rated house rentals in Edisto River

Guests agree: these houses are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1

Top guest favorite

A modern kitchen features stainless steel appliances and a spacious island with a sink. Light streams through large windows dressed in sheer curtains. A dining table with several chairs is positioned nearby, enhancing the functional layout of the space.

Home in Wadmalaw Island

4.98 out of 5 average rating, 102 reviews

Hart Estates: 2 bedroom retreat on Wadmalaw Island

Cozy Coastal Escape on Beautiful Wadmalaw Island 🌊 Unplug, unwind, & experience true Lowcountry charm at this peaceful island retreat just outside of Charleston. 🏡 Spacious cozy 2-bedroom home thoughtfully built by the Hart family ✨ Professionally cleaned ☀️ Light-filled spaces perfect for slow mornings & relaxed evenings ⏰ Early check-in when possible (available for an additional fee) 🧳 Complimentary early luggage drop-off 📍Lifelong local host happy to share insider tips & recommendations

LocationFamilyHeating

Guest favorite

A serene pathway leads from the grassy area towards a wooden dock extending into the calm waters of the Stono River. Lush greenery is visible on either side, framed by a tall palm tree and dotted with low shrubs, under a clear blue sky.

Home in Johns Island

4.94 out of 5 average rating, 137 reviews

Waterfront home w/ Deepwater dock on Stono River!

3bd/2bath waterfront home with deep water dock on the Stono River on Johns Island! Beautiful lot in quiet neighborhood, with large majestic live oaks. Enjoy beautiful views of the Stono River from the sunroom or patio, ideal for catching pretty sunsets! Great fishing and crabbing right off dock as well as boating, kayaking, or swimming. Bring your own boat to keep at dock! Located across from public boat landing! 2 kayaks, crab pot and 4 bikes included. Come and enjoy this beautiful property!

FamilyLocationBackyard

Top guest favorite

The living area showcases a stylish design with a neutral color palette. A plush, gray sofa and a matching loveseat are arranged around a glass coffee table. Natural light floods the space through large sliding doors that lead to the outdoor area. Decorative accents are present throughout.

Home in Ladson

4.92 out of 5 average rating, 143 reviews

Ibis Landing

This property has undergone a complete renovation. It now features a beautiful style and design that is sure to impress. Enjoy the granite countertops and stainless steel appliances in the fully equipped kitchen, relax on the back patio with a charcoal grill and spacious eating area. Sleep soundly on Bloomingdales Premium Cotton Sheets and Turkish Towels in beautifully decorated bedrooms. The perfect combination of modern luxury and classic charm. Book your stay today and experience yourself!

FamilyValueParks

Guest favorite

A welcoming living room features a spacious gray sectional sofa paired with patterned accent chairs. A large coffee table sits at the center, surrounded by a textured area rug. Natural light filters through the window with blinds, and a flat-screen TV is mounted on the wall.

Home in West Ashley

4.96 out of 5 average rating, 160 reviews

Charming 2BR | Near Downtown, Airport & Beaches

Welcome to The Hidden Getaway! Our newly renovated home is located in West Ashley, convenient to local dining & shopping. About 6 miles to historic downtown Charleston, 8 miles to Charleston Int'l Airport, 1.5 miles to Founders Hall & Legare Waring Home at Charles Towne Landing. Craving a beach day? Folly Beach, Sullivan's Island & Isle of Palms are all just a 20-25 minute scenic drive away. Whether here to explore our rich history or savor our incredible cuisine, you'll love our location.

ValueFamilyHeating

Top guest favorite

A wooden staircase descends towards a dock on serene waters, framed by tall grasses. A blue roofed structure is positioned at the water's edge, with boats visible nearby. The sky is partly cloudy, reflecting natural light onto the calm surface.

Home in Beaufort

4.95 out of 5 average rating, 110 reviews

Belle Monte (beautiful mountain) on the water!

Belle Monte is a lovely light-filled 2 story home on high bluff overlooking Middle Creek off the Whale Branch river in Beaufort, SC. See gorgeous sunrises & watch the dolphins from the upstairs deck or sun porch. Great views of the water from most of the house. New lighted dock on deep water so bring your boat! Enjoy swimming (ladder provided), kayaking or paddle boarding. Great area for fishing and crabbing. Well-equipped kitchen, fireplace, gas grill, screened-in porch, game table & more!

ValueFamilyAccuracy

Guest favorite

The exterior of the house is framed by trees, featuring a wooden façade and a covered porch with a railing. The surrounding yard is grassy, providing a natural setting. A small staircase leads to the entrance, enhancing accessibility.

Home in Olar

4.95 out of 5 average rating, 185 reviews

The Pond House at Salkehatchie Farms

The Pond House is a secluded getaway in the woods with double glass doors throughout the house so you can enjoy nature, even while you are inside. It sits at the end of the winding drive through dogwoods in the spring, green trees in summer and colored leaves in autumn. There is a small pond on the edge of the property. Outdoor patios are a wonderful place to breathe in the early morning air, watch a sunset, or grill. There is plenty of room for walks and the property is yours to explore.

ValueLocationKitchen

Guest favorite

A spacious dining table is set for six with woven placemats, clear glassware, and decorative centerpieces. The screened-in porch offers views of lush trees and marshland, with overhead pendant lights casting a warm glow over the setting.

Home in Edisto Island

4.97 out of 5 average rating, 144 reviews

Marshfront Villa In The Trees - Near Beach & Bay

"The most unique and relaxing place to enjoy the tranquility and experience of Edisto. We did not want to leave" - Sambo Nestled atop 360-degree marsh views, you'll be immersed in the exotic natural beauty and wildlife of the Edisto sea island. Hear the waves crashing at the beach from the front porch and watch the marsh tides rise and fall from your choice of the many porches. "Nature with luxury.. our group loved floating from the house out to the inlet for private beach days" - JP

LocationFamilySleep quality

Top guest favorite

The image captures a serene landscape where sunlight filters through trees, casting long shadows on the grassy ground. Spanish moss drapes from branches, creating a tranquil and inviting scene alongside the waterfront.

Home in North Charleston

4.99 out of 5 average rating, 143 reviews

Waterfront Nature’s Retreat Cottage 2Bd/2B

Take it easy at this unique & tranquil waterfront getaway where you will be able to enjoy the stunning views of the Ashley river and beautiful sunsets over Magnolia Gardens. The 2 BR Cottage is located on 1.5 acres on private property Whether you are here for work or play, this property is centrally located: Min from airport, outlets, breweries, restaurants, I-26, 526, Boeing, 20 min from DT Charleston 30 min from the beach. NO PARTIES NO SMOCKING NO PET NO SWIMMING NO DOCK ACCESS 5 PERS

FamilyValueAmenities

Top guest favorite

The exterior of the villa is shown, featuring a light-colored stucco façade contrasted by large windows. Surrounding landscaped areas include planters with vibrant greenery and flowers. A gravel pathway leads to the entrance, framed by the natural beauty of trees in the background.

Home in Summerville

4.92 out of 5 average rating, 184 reviews

Guest House/Villa

Enjoy your stay at this immaculately designed new build Villa. Located on a family property surrounded by 2 acres of trees, in a quiet rural neighborhood. Lots of privacy, peace and quiet, yet only 5 minutes from restaurants and stores. 15 minutes from Downtown Summerville, 40 minutes from Charleston and various coastal attractions. The villa is separate from main house and has no shared space other than the driveway. NO smoking, No pets. Laundry service available for long stays.

LocationFamilyGetting around

Top guest favorite

A vibrant sunset casts warm hues over a tidal creek, reflecting beautifully on the still water. The scene is framed by lush greenery and a dock, providing a serene view of the marsh and surrounding trees.

Home in James Island

4.98 out of 5 average rating, 131 reviews

James Island Creek Retreat | On the Water |

Welcome to our Lowcountry home on James Island — tucked along a tidal creek in a quiet, family-friendly neighborhood. Our large backyard backs right up to the marsh, with water access and gorgeous views at every tide. You’re just 7 minutes from downtown Charleston and 10 minutes from Folly Beach — a perfectly central spot to explore everything the Lowcountry has to offer. As a licensed US Coast Guard captain, I also offer discounted private boat tours for guests.

LocationValueCondition

Top guest favorite

The charming bungalow features a white exterior and a welcoming front porch adorned with a daybed swing. Pink flowers are placed in pots, and an American flag adds a touch of character. Lush greenery surrounds the property, enhancing its inviting presence.

Home in Beaufort

5.0 out of 5 average rating, 105 reviews

Military/1st Res. Disc. Pet Friendly

The Sweet Magnolia Cottage, a charming 1942 bungalow. Enjoy the front porch with its daybed swing while sipping on your favorite beverage. Cook out & enjoy the barbecue grill and back porch. The cottage is an easy 1 mile walk to the Historic Beaufort Riverfront’s restaurants, shops, ice cream. Take a horse drawn carriage ride and learn the history of this charming town. Its location is approximately 15-20 minutes to Parris Island & the air station. Pet friendly.

ValueLocationWalkability

Guest favorite

A serene waterway is flanked by lush greenery and reflected clouds, creating a peaceful natural landscape. The calm waters mirror the sky, with a boat visible in the distance, indicating opportunities for exploration and relaxation.

Home in Johns Island

4.94 out of 5 average rating, 125 reviews

The River Girl, Private Dock, Great Outdoor Spaces

The River Girl is located on Johns Island, a beautiful 20 min drive to downtown Charleston, 20 min to Kiawah, & 20 to Folly Beach. We hope this place provides a comfy spot to rest your head at the end of a fun day exploring. We also want you to take advantage of the slow island life! Go crabbing off the dock and cook your supper! Read a book on the back deck & enjoy the breeze. Light a candle, & take a soak in the tub! Just enjoy yourself. Fully updated!

LocationValueDecor