House vacation rentals in Durham

Luxe Modern Retreat *Entire Duplex/ Both Units!*

This stylish modern retreat is sure to become your new favorite getaway. You’ll enjoy access to the ENTIRE DUPLEX (both units!), perfect for traveling with friends, family, or colleagues. Each of the 2 units boasts its own beautiful living room and kitchen, plus 2 bedrooms & 1 bathroom per side. Gather together on the inviting front porch, or enjoy dinner alfresco on the sunny back patio. Ideally situated just 1 mile from the heart of Durham, you’ll enjoy all the best the Bull City has to offer!

Modernist Masterpiece: 'Simply the Best'

Welcome to Hazel Modernist 6 - designed and built by Alicia Hylton-Daniel, with her "sister," Modernist 5, next door. Centrally located downtown, this gorgeous escape is truly livable. Fully equipped chefs kitchen opens into the large living & dining space, with Frame TV and fireplace. 3BR & private back deck offer plenty of space together or alone. Each home by Alicia is infused with creative and new design concepts. This glamorous home celebrates the essence of Tina Turner, Simply the Best.

The Old Cottage House

Enjoy the tranquility of this beautiful home with stunning views of the pond & surrounding nature. The outdoor fireplace is perfect for gathering around, & the indoor fireplace adds cozy ambience to the living room. The large porch allows you to relax with a book or simply take in the scenery. Stroll down to the dock, where you enjoy the peaceful surroundings. This home provides the ideal retreat from everyday life, allowing true relaxation. Book your stay & experience the beauty of this home.

Luxury Modern Suite W/ Private Deck

Welcome to our Private Luxury Master Suite! Enjoy a hotel-like experience with a spacious luxury bath featuring double sinks and a rain shower and a beautiful private deck with a peaceful view. We also include a coffee bar, work area, Wi-Fi, and TV. Conveniently located from RDU Airport and Downtown Durham, with a variety of restaurants and coffee shops nearby. Experience the perfect blend of comfort, luxury, and convenience in this upgraded suite! Parking is available and limited to 1.

Artist-Designed Cabin Near Duke & Downtown

Relax and recharge in a modern, artist-designed passive solar home tucked into the woods just minutes from downtown Durham and Duke University. This cabin-style retreat blends nature, comfort, and convenience — ideal for weekend getaways, visiting Duke, or extended stays. Inside you’ll find original artwork, abundant natural light, and a professionally equipped kitchen. Outside, enjoy birdsong and mature trees while staying close to Durham’s restaurants, coffee shops, breweries, and shopping.

Near Duke, Southpoint, UNC

Discover the perfect retreat in South Durham, NC! Our tranquil Airbnb offers an idyllic escape with a prime central location that guarantees a memorable stay. Start your morning on the inviting screen porch, where you can relish a cup of coffee and take in the view of the flower garden before headed out to enjoy some of the Triangle's finest attractions. Convenience is at your fingertips, as our Airbnb is just minutes away from RTP, RDU airport, Downtown Durham, DUKE, UNC, and the DPAC.

Clean Quiet Medical&Work Stay, Fenced Yard, Pets

Welcome to a spotlessly clean, quiet, and comfortable home in downtown Durham, thoughtfully set up for medical stays, longer work visits, and guests traveling with pets. Many guests choose this home while visiting Duke University Hospital, the VA Hospital, or Duke University, and appreciate having a calm place that feels easy to live in during what can be stressful or busy times. This is not a party house —it’s a peaceful, practical space designed to help you rest, reset, and settle in.

Guest Suite: Artist studio turned into loft.

A guest suite that's a former artist studio with 10-15 foot high windows and 20 foot high ceiling, converted into one bedroom loft with private entrance, bath, living area, and kitchenette. The space is attached to the rest of my house, but you'll have a private entrance, your own bathroom, living area and kitchenette and two seat dining table. You will not have access to a full kitchen. The open-concept design and high balcony ledge are unsuitable for children under the age of 10.

Luxurious Modernist Tree House

Stunning, private, and truly one-of-a-kind—this unique home is perfect for a vacation, staycation, special occasion, or simply celebrating everyday life. Designed by renowned modernist architect Frank Harmon. The 2,128-square-foot residence sits on 1.3 acres and was crafted with meticulous attention to detail. Inside, you’ll feel nestled among the treetops while remaining conveniently close to restaurants, shopping, downtown Raleigh, WakeMed, UNC, Duke, and Research Triangle Park.

Newly Renovated 3 BR home in convenient location!

Newly renovated space to relax and explore the best of Durham. Sleeps 6 with plenty of space to spread out. Well located - only 10 minutes to Duke, Duke Hospital, downtown and Ninth/Broad Street areas. Enjoy use of the fully stocked kitchen, comfortable living area, dining space and spacious back deck and screened in porch. Grill out and enjoy the back yard. Great for families and groups of friends or business travelers. Several restaurants close by and easy access to highways.

Comfy bungalow (2 BR, 1BA) for any travel need

This 1950 bungalow is a spacious, peaceful and comfortable place to stay for any travel need. It has two workstations, high-speed wifi, 4K TV, and a well-equipped kitchen with new appliances. The backyard is large with a grill and seating area overlooking oak trees. The bungalow is located right next to Northgate Park, with dog parks, tennis courts, picnic area and walking trails. Downtown, Duke University, Duke Medical Center and Duke Hospital are just a short bike ride away.

Calming Woodland Octagon

Take a much needed break from the stresses of the city at this unique property nestled in old growth woodland. Indulge in the sound of the wind and a sea of stars. Make friends with your neighbors: deer, squirrels, hawks and fireflies. A haven for writers, artists, dancers, remote workers and nature lovers only 15 minutes from Chapel Hill and 8 minutes from Jordan lake. You'll find Zen, fiber internet, and more than a little magic here.