Pet-friendly vacation rentals in Central Business District

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Central Business District

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
A cozy living room is presented, featuring a comfortable gray sofa and a blue accent chair. A glass coffee table sits in the center, accompanied by a potted green plant. Natural light filters through a window, enhancing the inviting atmosphere.
Home in Louisville
4.99 out of 5 average rating, 203 reviews

Nulu Liberty House

This beautifully updated home was named the #1 PET FRIENDLY Airbnb in Louisville by Trip101! Located in Louisville's hottest neighborhood, you'll be a short walk from a variety of restaurants, bars, local coffee shops, parks, bourbon distilleries and more! The kitchen and living room are inviting and fully stocked for you to relax with friends. All 3 bedrooms are spacious and comfortable and designed for you relax and make the most of your trip to beautiful Louisville. We can't wait to host you!

Guest favorite
A charming red brick building exhibits a vibrant yellow entrance, flanked by manicured greenery and trees. Large windows invite natural light, while a wrought-iron fence surrounds the inviting front yard, completing the home’s welcoming exterior.
Home in Butchertown
4.84 out of 5 average rating, 233 reviews

NuLu & Angel’s Envy at Your Door| Great for Groups

This spacious, personality-filled home in the heart of downtown is the perfect base for bourbon trail weekends, weekday corporate stays,or family get-togethers. You can walk everywhere! With 3,000 sq ft of flexible space it's great for group connection; there's a private patio, plenty of gathering zones, comfy beds, a chef’s kitchen, and thoughtful touches that make your stay feel special. The home is soulful and full of character—ideal for groups who value comfort, style, and a great location.

Guest favorite
A spacious loft-style kitchen is highlighted by a modern white table surrounded by metal chairs. A vintage neon sign reading 'Louisville' adds a pop of color against the textured wall. Natural light pours in through large windows, reflecting off shiny purple floors.
Condo in Central Business District
4.95 out of 5 average rating, 240 reviews

★ Victorian Louisville ★ 1000 sqft Glassworks Loft

Fresh, modern and sleek 950 SqFt loft style unit. Constructed inside the historic glassworks building, this condo is one of the most unique in the city. You will be amazed by the style, but also the amenities nearby. With a 2 minute walk to Museum row, and a 7 minute walk whiskey row, the convention center, the YUM! center and the center for the arts - everything is nearby. With Wifi, Netflix, and Hulu provided you have everything you need. The perfect spot for relaxing or going out on the town.

Top guest favorite
Home in Cherokee Triangle
4.94 out of 5 average rating, 178 reviews

2 br home, walking distance to much entertainment

Home located in the historic Irish Hill neighborhood, just a short walk to popular Baxter Ave and Bardstown Rd, famous for its restaurants, coffee shops and nightlife. Downtown and Nulu are a very short drive away, many great bars and distilleries are walking distance. Home built in 1879, entirely renovated with a modern kitchen, fully fenced backyard, private parking and fire pit.Master bedroom has a king size bed and it’s own bathroom with jetted tub. We look forward to your visit, thank you!

Guest favorite
A living room features a modern grey sofa adorned with an orange throw, positioned near a wooden entertainment unit and a wall-mounted television. An acoustic guitar stands next to a light wood accent chair, while a vibrant landscape painting decorates the wall above an ornate fireplace.
Home in Irish Hill
4.95 out of 5 average rating, 272 reviews

Kentucky Hug: A Modern Shotgun for Bourbon Elites

A “Kentucky Hug” is the warm feeling one gets after sipping whiskey. Get that feeling at this renovated shotgun home in centrally and conveniently-located Irish Hill! One block away from Baxter Ave-- the original Highlands! One mile to a few urban bourbon distilleries. A quick Lyft to NULU, Butchertown, Clifton, the convention center, and KFC Yum Center. Easy access to I-64, I-65, and I-71. Walking distance to Headliners Music Hall, Gravely Brewing, and other great eats. Permit No: STR926031

Top guest favorite
A welcoming exterior view of a stylish house features a covered front porch with seating and decorative elements. The spacious interior showcases a cozy living area with comfortable seating and art on the walls. A well-maintained outdoor space includes a putting green. Natural light brightens the rooms.
Home in Jeffersonville
4.99 out of 5 average rating, 103 reviews

Walking Bridge, Putt Putt House

NEW LISTING: Welcome to our walking bridge home on Pearl St. We have a hot tub, putt putt, and all the fun you can think of in one home. Steps away from restaurants, shopping, and bars, as well as the walking bridge to Louisville. This home is closer to the fun in Louisville than most neighborhoods in Louisville itself. Go out or stay in, you're guaranteed to have a great time in this newly renovated gem. We have high quality mattresses, and smart TV's in both bedrooms and the living room.

Top guest favorite
A cozy living area is highlighted by a collection of framed artworks and wall decor, reflecting a mix of styles. A gray sofa sits in front of a vibrant red door, while a person stands on a ladder, adjusting the arrangement of the art pieces.
Apartment in East Market District
4.97 out of 5 average rating, 242 reviews

Historic Braden Suite in heart of NuLu action

This spacious suite pays tribute to Louisville’s own Anne Braden in true urban style! Located in a lovingly renovated antebellum church (1843), it features a full kitchen, beautiful bathroom, a queen bed, and a sleeper sofa. You'll be in the middle of all Market Street has to offer — steps from Rabbit Hole Distillery, Nouvelle Wine Bar, Garage Bar, and tons more. A 10-minute ride from the airport, you'll be half a mile from Slugger Field, and 1 mile from the YUM! and Convention Centers.

Guest favorite
The exterior of a charming single-story house is shown, featuring a covered porch and stone columns. Lush green bushes frame the entrance, and two seats are visible on the porch. A modest yard surrounds the house, with a clear sky above.
Home in Clifton Heights
4.9 out of 5 average rating, 294 reviews

Quiet Neighborhood Home With Outstanding Location

Situated on a quiet hilltop neighborhood in Clifton Heights, this is the perfect location for a professional or personal visit to Louisville and very animal friendly. It is within 10 minutes of Downtown, Waterfront Park, Nulu, Frankfort Avenue, the Highlands, the Convention Center, and just 15 minutes from historic Churchill Downs. These neighborhoods feature the best dining and entertainment in the city. Just a block away is the Mellwood Arts Center complex with shops and dining.

Top guest favorite
A modern kitchen features navy blue cabinetry paired with white tiled backsplashes. Stainless steel appliances, including an oven and microwave, are complemented by a gold faucet. A large window allows natural light, reflecting off the light countertops and showcasing the organized space.
Tiny home in Irish Hill
4.95 out of 5 average rating, 188 reviews

Trendy Tiny Home w/ King Bed Loft

Unique experience in style! Enjoy a weekend or an extended stay at this charming carriage house just walking distance to popular restaurants, breweries and local shops. The location is perfect! Inside you'll find a fully equipped kitchen, bathroom, living room with a 55" smart tv, a dedicated work space/desk and a king sized bed in the loft. Guests will have privacy with self-check in smart locks and a dedicated parking space. We can't wait to host you!

Guest favorite
An open living space features exposed brick walls and knotty wood floors. A dining table with black chairs is positioned near a kitchen area, alongside a cozy seating arrangement with a leather couch and armchair. Natural light enters through large windows, enhancing the room's warm ambiance.
Home in New Albany
4.96 out of 5 average rating, 112 reviews

Firepit/Gaming/Historical bldg.

Only a 1 min drive to the revitalized heart of New Albany and short 7 minute drive to downtown Louisville. This stylish 2 br 1 1/2 ba loft like flat was a grocery in the early 1900s. It was renovated to bring back the exposed brick wall, beams and knotty wood floors. The-remodeled bathroom has a new soaking tub and stand in shower. The middle BR also has a futon that pulls out to sleep 2 more. There is also an outdoor firepit on a paved area.

Top guest favorite
A cozy seating area features a modern sofa and a small side table, positioned on a patterned rug. Natural light filters through sheer curtains, illuminating the dark walls. Nearby, a door leads to the exterior, while colorful artwork decorates the walls.
Guest suite in Shelby Park
4.98 out of 5 average rating, 638 reviews

Eco+ guest suite in the center of all the fun

Hip modern amenities meet historic home in Shelby Park. A quick drive to everything in the urban core - Downtown, Nulu, Old Louisville, the Highlands, Germantown, and more. Easy access to the airport, to boot! We are pet friendly home, but require your pets be registered on the booking. We want your pets (and ours) to be as safe and comfortable as you are, and the fee covers additional costs to complete allergen level sanitization.

Top guest favorite
A spacious living area is equipped with a large sectional sofa and a wooden coffee table, providing a comfortable gathering space. The modern kitchen features stainless steel appliances and dark cabinetry, while an open layout invites natural light from the adjacent windows.
Home in Germantown
4.95 out of 5 average rating, 147 reviews

The Caldwell Highlands/Germantown

Welcome to The Caldwell, a Germantown/Highland area home that includes three bedrooms, one and half bathrooms and sleeps up to five people. The home is within walking distance of several restaurants, bars, retail and vintage stores, and entertainment venues including the Germantown Gables, Logan Street Market and Old Forester’s Paristown Hall. The home features a covered deck, a fenced-in yard as well as home gym.

Popular amenities for Central Business District pet-friendly home rentals

When is the best time to visit Central Business District?

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Quick stats about vacation rentals that are pet-friendly in Central Business District

  • Total vacation rentals

    Explore 130 vacation rentals in Central Business District

  • Nightly prices starting at

    Central Business District vacation rentals start at ﺩ.ﺇ257 per night before taxes and fees

  • Verified guest reviews

    Over 4,070 verified reviews to help you choose

  • Family-friendly vacation rentals

    60 properties offer extra space & kid-friendly amenities

  • Vacation rentals with a pool

    30 properties feature pools

  • Rentals with dedicated workspaces

    120 properties have a dedicated workspace

  • Wi-Fi availability

    130 of Central Business District vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Central Business District rentals

  • 4.8 Average rating

    Central Business District stays are highly rated by guests—averaging 4.8 out of 5!

  • Nearby attractions

    Central Business District's top spots, include Fourth Street Live!, Louisville Slugger Museum & Factory, and Louisville Slugger Field

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