Vacation rentals in Central Business District

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Top-rated vacation rentals in Central Business District

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Home in Germantown
4.9 out of 5 average rating, 175 reviews

Bourbon Trail Spacious Backyard NEW HotTub Grill!

The Burnt Barrel, discover your vibrant Louisville getaway! Perfect for couples, business travelers, or event visitors, this cozy home offers high-speed Wi-Fi and a dedicated workspace, fully equipped kitchen, and a NEW hot tub and grill for you to enjoy! Guests rave about its comfort, walkable location, and modern amenities. Enjoy nearby bars and restaurants all just minutes from downtown, UofL Health, and the Convention Center. Experience true Louisville charm and convenience! Book a stay now!

Guest favorite
A spacious loft-style kitchen is highlighted by a modern white table surrounded by metal chairs. A vintage neon sign reading 'Louisville' adds a pop of color against the textured wall. Natural light pours in through large windows, reflecting off shiny purple floors.
Condo in Central Business District
4.95 out of 5 average rating, 253 reviews

★ Victorian Louisville ★ 1000 sqft Glassworks Loft

Fresh, modern and sleek 950 SqFt loft style unit. Constructed inside the historic glassworks building, this condo is one of the most unique in the city. You will be amazed by the style, but also the amenities nearby. With a 2 minute walk to Museum row, and a 7 minute walk whiskey row, the convention center, the YUM! center and the center for the arts - everything is nearby. With Wifi, Netflix, and Hulu provided you have everything you need. The perfect spot for relaxing or going out on the town

Top guest favorite
A living area features modern furnishings with a colorful patterned armchair and a bright pink sofa. A dark coffee table sits in the center, complemented by decorative items. Light enters through a window, with walls painted in a warm tone.
Apartment in Jeffersonville
4.99 out of 5 average rating, 179 reviews

Remodeled Riverfront Unit - Porch with River View

Completely remodeled 1820's riverfront apartment with a direct view of the Ohio River from the front deck. Enjoy a quick walk to restaurants, bars, shops, the Jeffersonville Ampitheater and the Big Four Walking Bridge to Louisville, KY. Minutes from KFC Yum Center, Louisville Slugger Field, Museum Row, the Kentucky International Convention Center and the Louisville City Soccer Stadium. Perfect, unobstructed view for Thunder over Louisville. Great for The Kentucky Derby. On site parking.

Guest favorite
An open living area features exposed brick walls and hardwood flooring, enhanced by natural light from large windows. A spacious leather couch is complemented by a wooden coffee table and two ceiling fans. The kitchen showcases a granite island and modern appliances.
Condo in Central Business District
4.9 out of 5 average rating, 271 reviews

Downtown Condo | Private 1 CAR Garage & Balcony

Beautiful Downtown Loft Condo with private balcony overlooking 4th Street. Walking distance to fantastic eateries, bars, concerts, ball games, and much more. Steps to the Palace Theater and 4th Street Live and next door to the Seelbach Hotel. Private 1 CAR, connected to the building for easy downtown parking. Building has secure entry and an elevator. The building is an old clothing department store, BYCKS. This 4th floor unit boasts exposed ceilings, brick walls, and hardwood flooring.

Top guest favorite
A bright and open living space showcases high ceilings with large windows allowing natural light to fill the area. The fully equipped kitchen features modern appliances, while a dining table accommodates several guests. A sectional sofa offers comfortable seating for relaxation.
Loft in Central Business District
4.93 out of 5 average rating, 163 reviews

Stunning Downtown Top Floor Corner Loft with Views

***Derby Week/Weekend requires a 3-night minimum.*** Ideal for conference guests, concert weekends, and bourbon tourists. Enjoy incredible views from this 8th-floor corner loft in a beautifully restored historic downtown building. With 1,200 sq ft of open space, you’re steps from the Kentucky Int'l Conv Center and the Urban Bourbon Trail, plus dining, nightlife, museums, Waterfront Park, Churchill Downs, medical centers, and the airport. Sleeps up to 6 with 3rd queen bed set up upon request.

Guest favorite
A spacious living area is depicted, featuring a comfortable gray sofa with decorative pillows positioned next to a side table. A modern kitchen with sleek cabinetry and stainless steel appliances is visible in the background. Large windows allow for ample natural light, illuminating the wood-style flooring.
Apartment in Central Business District
4.9 out of 5 average rating, 299 reviews

4th Street Suites - Opulent King Bed Suite

Live the best of Louisville in this sleek 1‑bed, 1‑bath downtown retreat! Perfect for couples, families, or friends, it features a cozy king bed, pullout couch, a fully stocked kitchen, and a bright living area. Wake up to city sights, stroll to restaurants and bars, then relax by the pool or hot tub, play a round in the golf simulator, or unwind with a game of pool in the clubhouse. This is your launchpad for adventure—or a quiet, stylish escape when it’s time to rest. Come make it yours!

Top guest favorite
A spacious sectional sofa is center stage in a modern living area. The room is brightened by large windows, showcasing views of the outdoors. A decorative rug adds color and warmth, while a round coffee table completes the inviting setup.
Condo in Central Business District
4.98 out of 5 average rating, 177 reviews

The Derby City Loft, luxury, walk to museum row

Located in historic downtown Louisville the Derby City Loft is a show stopper! This PENTHOUSE luxury condo offers stunning views and high end living. The open floor plan boasts 3 queen beds, curtains can be pulled to make it a 2 bedroom. Plus the oversized sectional sofa may sleep 2 comfortably as well. Fully stocked kitchens and bathrooms with everything! This home was designed and styled with your comfort in mind, kick back, relax and enjoy high style living at the Derby City Loft.

Top guest favorite
A cozy living area is highlighted by a collection of framed artworks and wall decor, reflecting a mix of styles. A gray sofa sits in front of a vibrant red door, while a person stands on a ladder, adjusting the arrangement of the art pieces.
Apartment in East Market District
4.97 out of 5 average rating, 245 reviews

Historic Braden Suite in heart of NuLu action

This spacious suite pays tribute to Louisville’s own Anne Braden in true urban style! Located in a lovingly renovated antebellum church (1843), it features a full kitchen, beautiful bathroom, a queen bed, and a sleeper sofa. You'll be in the middle of all Market Street has to offer — steps from Rabbit Hole Distillery, Nouvelle Wine Bar, Garage Bar, and tons more. A 10-minute ride from the airport, you'll be half a mile from Slugger Field, and 1 mile from the YUM! and Convention Centers.

Top guest favorite
A comfortable seating area features a sectional sofa in a neutral tone, with a large area rug beneath. Exposed brick walls and multiple windows allow natural light to brighten the space. A television is positioned on a wooden stand alongside bookshelves filled with vinyl records.
Loft in Central Business District
4.97 out of 5 average rating, 1,140 reviews

Derby City Loft - Free downtown parking!

If this loft is booked, please check out my other listings.. https://www.airbnb.com/h/bourbon-city-loft https://www.airbnb.com/h/river-city-loft Spacious 900 sq. ft. loft located in the heart of downtown Louisville. Walking distance to shops, restaurants, bars and 1 block from 4th Street Live! You'll be 4 blocks from the YUM! Center, 2 blocks from the Kentucky International Convention Center, and less than 10 minutes from Churchill Downs! Free parking in a secured parking garage!

Guest favorite
A bright bedroom features a spacious bed with a red throw blanket and neatly rolled towels. Two bedside tables with stylish lamps flank the bed. Three abstract art pieces hang on the wall above, while large windows provide natural light and a view of the outside.
Apartment in Central Business District
4.92 out of 5 average rating, 129 reviews

Modern Apartment• King Bed, Heated Pool + Hot Tub

Enjoy everything Louisville has to offer from this luxury apartment, perfect for up to 4 guests. Rest easy on a comfortable king bed or memory-foam sleeper sofa, then wake up to complimentary coffee and sunrise city skyline views. Walk to top restaurants and entertainment, including 4th St. Live!. End your day with a virtual golf game, a workout in the 24/7 gym, a soak in the hot tub, or a relaxing movie night. Comfort, location, and amenities come together book your stay today.

Guest favorite
A welcoming entryway is presented with a wooden table displaying local brochures and a chalkboard sign that reads 'Welcome to the Ville.' The walls are decorated with framed images and memorabilia, while a ladder adds an artistic touch to the space.
Condo in Central Business District
4.91 out of 5 average rating, 154 reviews

Winner's Circle: Comfy Downtown King Free Parking

Centrally located - enjoy easy walkable access to all of downtown Newer condo in historic Theatre Building Elevator access in building Next door to the Palace Theater 1 FREE parking space in parking garage High speed wi-fi 65" HDTV - cable & streaming Tourist Area - local shops, eateries and bourbon tasting rooms around 2 Blocks from 4th Street Live 0.6 miles to Convention Center 0.8 Miles to Whiskey Row & Yum! Center 3.6 miles to Churchill Downs 4 Miles to Expo Center/Airport

Guest favorite
A spacious living area is highlighted by a large flat-screen television mounted on the wall. Leather seating includes a brown armchair and a cozy chair with light upholstery. A decorative white planter sits atop a glass coffee table, accompanied by a magazine.
Condo in Central Business District
4.98 out of 5 average rating, 178 reviews

Charming Penthouse/Rooftop Patio/Downtown

Unwind and enjoy sweeping river views on the rooftop patio while staying in this private 5th floor Penthouse apartment. Intentionally designed and decorated. Features include: a full upscale kitchen, open concept living and dining area, cozy King bed, large plush bathroom, and laundry in the suite. Whether visiting for work or pleasure, this spacious urban suite is located on The Bourbon Trail and within walking distance to Louisville's most popular venues!

Popular amenities for Central Business District vacation rentals

When is the best time to visit Central Business District?

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Quick stats about vacation rentals in Central Business District

  • Total vacation rentals

    Explore 340 vacation rentals in Central Business District

  • Nightly prices starting at

    Central Business District vacation rentals start at ﺩ.ﺇ184 per night before taxes and fees

  • Verified guest reviews

    Over 19,440 verified reviews to help you choose

  • Family-friendly vacation rentals

    160 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 130 rentals that welcome pets

  • Vacation rentals with a pool

    60 properties feature pools

  • Rentals with dedicated workspaces

    220 properties have a dedicated workspace

  • Wi-Fi availability

    340 of Central Business District vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Gym, BBQ grill, and Laptop-friendly workspace across Central Business District rentals

  • 4.8 Average rating

    Central Business District stays are highly rated by guests—averaging 4.8 out of 5!

  • Nearby attractions

    Central Business District's top spots, include Fourth Street Live!, Louisville Slugger Museum & Factory, and Louisville Slugger Field

  1. Airbnb
  2. United States
  3. Kentucky
  4. Jefferson County
  5. Louisville
  6. Downtown