Vacation rentals in Central Business District

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Top-rated vacation rentals in Central Business District

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Apartment in East Market District
4.97 out of 5 average rating, 185 reviews

Derby Weekend Retreat | Designer Curated Stay

A thoughtfully curated stay by Jaclyn Journey Hospitality, designed with intention so you feel cared for while away from home. Set within a historic 19th-century building, the space celebrates character & charm while offering beautifully considered comforts throughout. Featured in Architectural Digest, DOMINO Magazine, Apartment Therapy, & more. Every detail has been hand-selected to delight the senses. The apartment is also shoppable, inviting you to take home a favorite piece of your stay.

Guest favorite
A spacious loft-style kitchen is highlighted by a modern white table surrounded by metal chairs. A vintage neon sign reading 'Louisville' adds a pop of color against the textured wall. Natural light pours in through large windows, reflecting off shiny purple floors.
Condo in Central Business District
4.95 out of 5 average rating, 259 reviews

★ Victorian Louisville ★ 1000 sqft Glassworks Loft

Fresh, modern and sleek 950 SqFt loft style unit. Constructed inside the historic glassworks building, this condo is one of the most unique in the city. You will be amazed by the style, but also the amenities nearby. With a 2 minute walk to Museum row, and a 7 minute walk whiskey row, the convention center, the YUM! center and the center for the arts - everything is nearby. With Wifi, Netflix, and Hulu provided you have everything you need. The perfect spot for relaxing or going out on the town

Top guest favorite
The living area features large windows allowing natural light to fill the space. A comfortable couch is positioned beside a rustic coffee table, with a dining area featuring bar stools in the background. Exposed brick walls and glossy concrete floors add character.
Condo in Central Business District
4.99 out of 5 average rating, 156 reviews

Glassworks Loft at Louisville Skyline

This unique and modern 850 square foot downtown loft is situated in the historic Glassworks building; boasting 12-foot ceilings and a wall of windows overlooking Louisville’s CBD and the Ohio river bridges / fireworks of Thunder. Enjoy all of the comforts of home with new scenery or venture out and relish our great city. Ideal for couples but can sleep 4 comfortably. Great for business or pleasure with close proximity to the KICC, Slugger Factory, Yum Center and 7 distilleries within 4 blocks.

Guest favorite
Apartment in East Market District
4.91 out of 5 average rating, 103 reviews

DERBY Ready! Stylish unit near Churchill Downs!

Discover “Pour Decisions,” a chic 3-story 2BR/2BA condo in Louisville’s vibrant NuLu district. Enjoy a cozy living room with Smart TV, a fully equipped kitchen, and two private patios, including a rooftop deck. The main suite features a plush king bed and ensuite bath. Just steps from NuLu, East Market District, Whiskey Row, Downtown, and top dining, this stylish retreat offers high-speed Wi-Fi, self-check-in, and modern comforts, your perfect Louisville getaway. Book your convenient stay now!

Top guest favorite
A spacious bedroom features a king-size bed with striped bedding, complemented by an orange accent pillow. The exposed brick wall adds character, while a small nightstand with a lamp sits alongside. Natural light filters through the window, illuminating the warm wood flooring.
Loft in Central Business District
4.97 out of 5 average rating, 940 reviews

Bourbon City Loft - Free downtown parking!

If this loft is booked, please check out my other listings.. www.airbnb.com/h/derby-city-loft www.airbnb.com/h/river-city-loft www.airbnb.com/h/falls-city-loft Spacious 950 sq. ft. loft located in the heart of downtown Louisville. Walking distance to shops, restaurants, bars and 1 block from 4th Street Live! Located 4 blocks from the YUM! Center, 2 blocks from the Kentucky International Convention Center, and less than 10 minutes from Churchill Downs! Free parking in a secured parking garage!

Top guest favorite
An open living area features a combination of hardwood flooring and a cozy rug. A large flat-screen TV is mounted on the wall, above a decorative fireplace. Comfortable seating is arranged with accent pillows, and a dining table is visible in the bright kitchen area.
Apartment in East Market District
4.98 out of 5 average rating, 299 reviews

Urban Bourbon Stay - Nulu 2 BR * 2 Full Bath

Beautifully renovated historic 2 bedroom 2 full bath apartment in Louisville's hip Nulu neighborhood. Huge 1,500 sq ft space to relax in after enjoying all the shops and restaurants in the Nulu area. This apartment is just a few blocks east of downtown. It's a great area to kickoff your Louisville adventures. This apartment is above a boutique wine and bourbon shop and within walking distance of several distilleries, so you don't have far to go to sample some of Kentucky's legendary bourbon.

Top guest favorite
A spacious sectional sofa is center stage in a modern living area. The room is brightened by large windows, showcasing views of the outdoors. A decorative rug adds color and warmth, while a round coffee table completes the inviting setup.
Condo in Central Business District
4.98 out of 5 average rating, 185 reviews

The Derby City Loft, luxury, walk to museum row

Located in historic downtown Louisville the Derby City Loft is a show stopper! This PENTHOUSE luxury condo offers stunning views and high end living. The open floor plan boasts 3 queen beds, curtains can be pulled to make it a 2 bedroom. Plus the oversized sectional sofa may sleep 2 comfortably as well. Fully stocked kitchens and bathrooms with everything! This home was designed and styled with your comfort in mind, kick back, relax and enjoy high style living at the Derby City Loft.

Guest favorite
Condo in Central Business District
4.93 out of 5 average rating, 220 reviews

Derby Depot Cozy 1BR Central Location Free Parking

The Theatre Building is a beautifully renovated Art Deco building listed on the Historical Register located next to the Palace Theater. You will enjoy easy access to all of downtown from our central location for fun or work. The unit has its own dedicated high speed (300MB) wi-fi connection, HDTV w/cable & streaming apps, as well as 1 FREE off-street, hotel garage parking space. There are numerous entertainment, shopping, dining and bourbon tasting options available within a short walk.

Top guest favorite
A spacious living area features a large sectional sofa and a coffee table, set on a textured area rug. A flat-screen television is positioned on an elegant TV stand, with large windows allowing natural light to illuminate the space.
Condo in East Market District
4.99 out of 5 average rating, 109 reviews

Walk to Bourbon Trail | NULU Gem | Gated Parking

Stay in the heart of NULU—this modern ground-floor condo puts you steps from Louisville’s best restaurants, bourbon stops, and local shops. Walk to favorites like Angel’s Envy and Rabbit Hole Distillery, enjoy all the NuLu dining, or head downtown in minutes for concerts, games, or events. The condo is comfortable, quiet, and thoughtfully set up—ideal for couples, solo travelers, or business stays, with gated parking, fast Wi-Fi, and everything needed for short or extended stays.

Guest favorite
A resort-style pool area is showcased, surrounded by a modern building with large windows. Lounge chairs are arranged along the deck, offering a space for relaxation. The pool features steps and a smooth surface, inviting guests to enjoy the water.
Apartment in Central Business District
4.92 out of 5 average rating, 247 reviews

4th Street Suites - Beautiful King Bed Suite

Wake up to the best of Louisville! Imagine starting your morning in a cozy king bed, strolling to 4th Street Live for brunch, and exploring nearby restaurants, bars, and theatres. Spend the afternoon lounging by the pool or soaking in the hot tub, then watch the city lights twinkle from the 7th‑floor terrace. This stylish suite is your launchpad for urban adventure—and a quiet, relaxing escape when it’s time to rest. Come make it yours and experience the heart of the city!

Guest favorite
A spacious rooftop patio is highlighted by stylish furniture, including a large sectional and coffee table. Potted plants add greenery, while a scenic river view stretches in the background beneath a clear blue sky filled with light clouds.
Condo in Central Business District
4.98 out of 5 average rating, 182 reviews

Charming Penthouse/Rooftop Patio/Downtown

Unwind and enjoy sweeping river views on the rooftop patio while staying in this private 5th floor Penthouse apartment. Intentionally designed and decorated. Features include: a full upscale kitchen, open concept living and dining area, cozy King bed, large plush bathroom, and laundry in the suite. Whether visiting for work or pleasure, this spacious urban suite is located on The Bourbon Trail and within walking distance to Louisville's most popular venues!

Guest favorite
A light-filled living area features a comfortable sofa adorned with soft throw pillows and a cozy blanket. A modern coffee table displays a decorative arrangement of flowers, while a colorful artwork of a tree enhances the inviting atmosphere. Large windows provide views of the surrounding buildings.
Apartment in Central Business District
4.96 out of 5 average rating, 157 reviews

Stylish DT Apt • King Bed, Gym, Pool + Hot Tub

This stylish, luxury apartment is ideal for couples, families, and small groups. Step inside to modern finishes, updated appliances, and thoughtfully designed décor with everything you need for a comfortable stay. Rest easy on a plush bed, then head out to explore Louisville top attractions, dining, and entertainment are just steps away. Prefer to stay in? Enjoy on-site amenities including a gym, rooftop access, and a golf simulator. Book your stay today.

Popular amenities for Central Business District vacation rentals

When is the best time to visit Central Business District?

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Quick stats about vacation rentals in Central Business District

  • Total vacation rentals

    Explore 350 vacation rentals in Central Business District

  • Nightly prices starting at

    Central Business District vacation rentals start at ﺩ.ﺇ220 per night before taxes and fees

  • Verified guest reviews

    Over 20,620 verified reviews to help you choose

  • Family-friendly vacation rentals

    170 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 150 rentals that welcome pets

  • Vacation rentals with a pool

    50 properties feature pools

  • Rentals with dedicated workspaces

    250 properties have a dedicated workspace

  • Wi-Fi availability

    340 of Central Business District vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Central Business District rentals

  • 4.8 Average rating

    Central Business District stays are highly rated by guests—averaging 4.8 out of 5!

  • Nearby attractions

    Central Business District's top spots, include Fourth Street Live!, Louisville Slugger Museum & Factory, and Louisville Slugger Field

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  4. Jefferson County
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