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Vacation rentals in Doña Ana

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Top-rated vacation rentals in Doña Ana

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Top guest favorite
Guesthouse in Las Cruces
4.96 out of 5 average rating, 226 reviews

Quaint casita for 2

*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Guest favorite
Guesthouse in Las Cruces
4.87 out of 5 average rating, 294 reviews

Studio Casita 5 mins to Farmer's mkt/dogs welcome!

We welcome you to our cozy guest house in the heart of Downtown Las Cruces. Perfect for overnights with dogs or kiddos! Close to shopping, the Farmer's Market, and centrally located to enjoy all Las Cruces has to offer. You will have a private entrance, off-street parking, and a fenced yard to yourself. There is a queen bed and a pack-n-play as requested. There is a small kitchenette with a fridge, microwave, sm hot plate, and sink and the casita is equipped with utensils and the basics for you.

Guest favorite
A room features a spacious bed dressed in white linens, complemented by a dark blue throw pillow. Natural light filters in through sheer curtains. A small table with a microwave and refrigerator is visible, along with a black rug on the floor and a fan in the corner.
Guest suite in Las Cruces
4.93 out of 5 average rating, 614 reviews

Tiny Cute Cubby in Telshor Hills, Private Entrance

The Cubby is perfect for overnight or short-term stays. Zero contact check-in and check-out. Access to central Las Cruces. Close to NMSU, Mesilla Valley Mall, major medical centers, and major event facilities. Located in Telshor Hills, a quiet neighborhood with plenty of mature trees and vegetation. Close proximity to observatory, minimal light pollution. Gorgeous views of Organ Mountains and Tortugas Mountain (A Mountain). Ten minute drive from historic Mesilla. Close to various hiking trails.

Top guest favorite
The living area features an open layout with a spacious couch, accent chairs, and a decorative coffee table on a colorful area rug. A television is positioned against a light wall, with artwork depicting floral designs hung above. Natural light enters through various windows.
Home in Las Cruces
4.99 out of 5 average rating, 136 reviews

Bonita Casita

This is a centrally located, remodeled 2 bedroom, 2 bathroom townhouse, very convenient to HWY 70, a straight shot to White Sands National Park, and Main Street, easy access to Downtown Las Cruces, home to Las Cruces's Farmer's Market. This townhouse features a split and open floor plan, full kitchen with everything you need to prepare a meal, dishwasher, microwave and gas cooking. You will also find an office and outdoor seating area. The property is located very near the lovely 4-Hills Park.

Guest favorite
Home in Mesilla Park
4.94 out of 5 average rating, 155 reviews

Conway Cottage 2

Step into your newly renovated one-bed, one-bath haven located at the heart of Mesilla Park. Enjoy a leisurely walk to Picacho Roasters for a delightful coffee experience, or hop on a cruiser bike for a charming ride to historic Mesilla. Immerse yourself in the local ambiance, sipping a drink to the backdrop of live music. As the morning sun rises, take a stroll amidst century-old trees that grace Conway Avenue. Welcome home to a blend of modern comfort and the timeless charm of Mesilla Park.

Top guest favorite
An outdoor seating area is highlighted by four Adirondack chairs arranged around a glowing gas fire pit. A stone wall forms the background, while a dining set is visible in the distance, with soft evening light creating a serene atmosphere.
Home in Las Cruces
4.95 out of 5 average rating, 142 reviews

Luxury Southwest Retreat

Our home provides comfort, relaxation, and convenience in an invitingly decorated setting. Three rooms offer various sleeping arrangements to meet all of your needs. Choose from a king, queen, or twin beds. Fully equipped and thoughtfully appointed kitchen provides for all of your meal needs. Luxurious backyard with Adirondack chairs, gas fire pit, porch rocking chairs, and outdoor dining set allow for relaxing and socializing. Washer & dryer available, detergent and fabric softener provided.

Top guest favorite
A spacious living area is showcased, featuring a large sectional sofa with contrasting black pillows. Light wood beams accent the ceiling, while large windows provide a view of the outdoor space. A modern coffee table sits on a textured area rug, enhancing the inviting atmosphere.
Home in Las Cruces
4.99 out of 5 average rating, 206 reviews

Modern Luxury Home

This Luxury Modern Home is made to suit all guests! Whether you are looking for a weekend getaway or a place for work and play, this home has everything to offer in beautiful Las Cruces, NM. Located in a brand new neighborhood near Red Hawk Golf Course and multiple family-friendly parks. Guests can rest peacefully in one of 4 bedrooms and enjoy amenities such as an outdoor grill, outdoor living area, lawn games, board games, and most kitchen items. High-speed Internet included and SmartTVs.

Top guest favorite
The exterior of a Southwestern home is showcased, featuring adobe-style architecture with a textured beige facade. A two-car garage is visible, along with a gravel front yard and desert landscaping, highlighted by rocks and sparse vegetation under a clear blue sky.
Home in Las Cruces
4.87 out of 5 average rating, 325 reviews

Casa Miranda, The Organ Mountains Looking House

Experience your clean, comfortable & spacious Southwestern home in Las Cruces, NM, now with a brand new refrigerated AC system. Your home has wonderful amenities: a fully stocked kitchen, washer/dryer, iron, comfortable beds (king & queen size), 65' flat screen TV in the living room with Wifi, secure two car garage, and a backyard with a breathtaking view of The Organ Mountains. Located minutes from both I-25/ US-70, easily get to downtown, Mesilla, NMSU, White Sands, and The Lincoln Forest.

Guest favorite
A gray sofa is positioned against a neutral wall, accented by colorful wall art in a grid formation. Decorative pillows adorn the sofa, while a small wooden bedside table with a lamp stands nearby, providing a cozy atmosphere.
Townhouse in Las Cruces
4.93 out of 5 average rating, 319 reviews

Casita Alegre (happy little house)

You will be comfortable in this cozy, newly built, smoke-free, and pet free townhouse. Private entrance and private garage are available exclusively. Easy access to interstates 10 and 25 and Highway 70 including White Sands, New Mexico State University, and downtown area. Bird watchers will love the easy access to all the sites nearby. Quiet neighborhood with minimal traffic. Enjoy the lovely sunset views from the back patio area. Close to restaurants, movie theaters, and shopping.

Superhost
The image captures a clear salt-water pool with sparkling turquoise water under a bright blue sky. Sunlight reflects off the surface, while a yellow flowering tree and lounging chairs are visible in the background, creating a serene outdoor space.
Shipping container in Las Cruces
4.91 out of 5 average rating, 1,068 reviews

Nature Retreat 12-min from Downtown (with pool)

Re-purposed 40-foot shipping container w/Ikea cabinets & furniture at edge of desert. Loft is 1 of 2 dwellings on 5-acre lot, private exterior doors & adjacent reserved parking. Picture window with wonderful view of Organ Mountains. Compact kitchen, Serta PillowTop queen size bed, full bathroom, LED lighting, cooled/heated by modern heat pump, Wi-Fi Internet. Pool access in season (usually April-October). Hike/bike from doorstep. Pet-friendly, see House Rules for details/cost.

Top guest favorite
The entrance features a traditional adobe archway with purple wooden doors flanked by a rustic ladder. A lantern hangs above the opening, while desert vegetation is visible to one side. The backdrop includes distant mountains under a clear blue sky.
Guesthouse in Las Cruces
5 out of 5 average rating, 276 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Superhost
Two green shipping containers are arranged symmetrically, creating a modern loft design. Large glass doors lead into each unit, surrounded by a gravel landscape. A young tree is planted in the foreground, enhancing the contemporary feel against the clear blue sky.
Shipping container in Las Cruces
4.9 out of 5 average rating, 786 reviews

#1 Shipping Container Loft Downtown

Shipping container loft constructed of 2 40-foot containers, furnished with Ikea cabinets/furniture. Loft is one of 4 on a half-acre fenced lot, each with private exterior doors & adjacent reserved parking spaces. Picture window with Organ Mountains view. Full kitchen, king size bed, full bathroom w/washing machine, LED lighting, cooled/heated by modern heat pumps. Wi-Fi Internet & TV, near bike path and downtown. Pet-friendly, please see House Rules for details/cost

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