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Vacation rentals in Doña Ana

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Top-rated vacation rentals in Doña Ana

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Top guest favorite
Guesthouse in Las Cruces
4.96 out of 5 average rating, 204 reviews

Quaint casita for 2

*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Top guest favorite
The living area features an open layout with a spacious couch, accent chairs, and a decorative coffee table on a colorful area rug. A television is positioned against a light wall, with artwork depicting floral designs hung above. Natural light enters through various windows.
Home in Las Cruces
4.99 out of 5 average rating, 127 reviews

Bonita Casita

This is a centrally located, remodeled 2 bedroom, 2 bathroom townhouse, very convenient to HWY 70, a straight shot to White Sands National Park, and Main Street, easy access to Downtown Las Cruces, home to Las Cruces's Farmer's Market. This townhouse features a split and open floor plan, full kitchen with everything you need to prepare a meal, dishwasher, microwave and gas cooking. You will also find an office and outdoor seating area. The property is located very near the lovely 4-Hills Park.

Top guest favorite
A spacious living area is showcased, featuring a large sectional sofa with contrasting black pillows. Light wood beams accent the ceiling, while large windows provide a view of the outdoor space. A modern coffee table sits on a textured area rug, enhancing the inviting atmosphere.
Home in Las Cruces
4.99 out of 5 average rating, 190 reviews

Modern Luxury Home

This Luxury Modern Home is made to suit all guests! Whether you are looking for a weekend getaway or a place for work and play, this home has everything to offer in beautiful Las Cruces, NM. Located in a brand new neighborhood near Red Hawk Golf Course and multiple family-friendly parks. Guests can rest peacefully in one of 4 bedrooms and enjoy amenities such as an outdoor grill, outdoor living area, lawn games, board games, and most kitchen items. High-speed Internet included and SmartTVs.

Top guest favorite
The exterior of a Southwestern home is showcased, featuring adobe-style architecture with a textured beige facade. A two-car garage is visible, along with a gravel front yard and desert landscaping, highlighted by rocks and sparse vegetation under a clear blue sky.
Home in Las Cruces
4.87 out of 5 average rating, 315 reviews

Casa Miranda, The Organ Mountains Looking House

Experience your clean, comfortable & spacious Southwestern home in Las Cruces, NM, now with a brand new refrigerated AC system. Your home has wonderful amenities: a fully stocked kitchen, washer/dryer, iron, comfortable beds (king & queen size), 65' flat screen TV in the living room with Wifi, secure two car garage, and a backyard with a breathtaking view of The Organ Mountains. Located minutes from both I-25/ US-70, easily get to downtown, Mesilla, NMSU, White Sands, and The Lincoln Forest.

Superhost
A cozy living room is depicted, featuring a comfortable dark sofa with decorative cushions. A large piece of wall art displays two figures sitting on a bench, creating a sense of connection. An antique trunk and a decorative green vase enhance the inviting space.
Earthen home in Las Cruces
4.84 out of 5 average rating, 620 reviews

Southwest Mexican Adobe Casa Historic District

This wonderful adobe home with refrigerated air is located directly in the heart of the city the Mesquite Historic District of Las Cruces. This Mexican home combines the neighborhood classic adobe style. Directly across the street is a Mexican cafe and a coffee shop. Seven minute walk to downtown which has wonderful pubs and restaurants. This home is located directly across the street from my other two casitas that are listed in Airbnb. Dog fee $10.00 which can be left on the table.

Top guest favorite
A cozy studio layout displays a comfortable bed with decorative pillows. A kitchenette is visible with storage for utensils and appliances, including a mini fridge and microwave. Warm yellow walls complement the rustic decor, enhancing the inviting ambiance of the space.
Apartment in Las Cruces
4.97 out of 5 average rating, 306 reviews

Casita on the Camino Real.

Cozy 260 sq. ft. studio apartment that can accommodate two adults Comfortable queen bed Large closet Kitchenette includes mini fridge, microwave, toaster oven, crock pot, rice cooker, French press, bar sink, cooking utensils and complete dinner service Full bath with tub Small dining table and chairs inside Wi-Fi Radio clock & USB ports Wall unit that is both AC and heat Small outside sitting area with seating and small outdoor kitchen with grill Off street parking Coded door entrance

Superhost
The image captures a clear salt-water pool with sparkling turquoise water under a bright blue sky. Sunlight reflects off the surface, while a yellow flowering tree and lounging chairs are visible in the background, creating a serene outdoor space.
Shipping container in Las Cruces
4.91 out of 5 average rating, 1,056 reviews

Nature Retreat 12-min from Downtown (with pool)

Re-purposed 40-foot shipping container w/Ikea cabinets & furniture at edge of desert. Loft is 1 of 2 dwellings on 5-acre lot, private exterior doors & adjacent reserved parking. Picture window with wonderful view of Organ Mountains. Compact kitchen, Serta PillowTop queen size bed, full bathroom, LED lighting, cooled/heated by modern heat pump, Wi-Fi Internet. Pool access in season (usually April-October). Hike/bike from doorstep. Pet-friendly, see House Rules for details/cost.

Top guest favorite
The entrance features a traditional adobe archway with purple wooden doors flanked by a rustic ladder. A lantern hangs above the opening, while desert vegetation is visible to one side. The backdrop includes distant mountains under a clear blue sky.
Guesthouse in Las Cruces
5 out of 5 average rating, 271 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Guest favorite
The exterior of a recently renovated tiny home features a modern design with a combination of beige and orange walls. A welcoming entrance is flanked by two planters, while a stone pathway leads to the door. Lush green grass enhances the outdoor space.
Tiny home in Las Cruces
4.92 out of 5 average rating, 212 reviews

Modern New Mexico Loft in the heart of Las Cruces.

Recently renovated tiny home with a loft-style bedroom. Many unique features will greet you in this very unusual space for Las Cruces. Downstairs there is a living room with a queen pull-out couch and a renovated kitchen that has everything you will need except an oven. Full 4 burner cooktop, microwave, full-sized fridge, and an eating bar. There is a small desk area for working, a shower bath (which is downstairs ), and a wonderful small outdoor space.

Guest favorite
An open living area is showcased, featuring a large sectional sofa facing a mounted television. A wooden coffee table sits in front of the sofa. The kitchen is visible, equipped with modern appliances and bar seating, while large windows provide ample natural light.
Home in Las Cruces
4.89 out of 5 average rating, 232 reviews

Modern Accessorized 3-Bedroom

This fully-furnished modern home is perfect for weekend getaways or longterm stays. With latest in appliances and style, the Powder River Villa offers the comfort of home with a luxury feel. Stream Netflix in front of the stacked stone fireplace, decompress in the pebble rain shower, or simply relax on the back porch to the beautiful New Mexico sunsets. This stylish space can be the romantic escape you're seeking or comfortably fit your group of 7.

Top guest favorite
A modern interior features a wooden dining table with two black chairs, accompanied by a decorative bowl. A wall hanging adds texture, while a metal rack displays clothing and a woven basket. Natural light filters through a nearby window, highlighting the clean lines of the space.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 195 reviews

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Top guest favorite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 184 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Popular amenities for Doña Ana vacation rentals

  1. Airbnb
  2. United States
  3. New Mexico
  4. Doña Ana County
  5. Doña Ana