
House vacation rentals in DeSoto County
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Top-rated house rentals in DeSoto County
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Hernando Hideaway (Entire Lakehouse)
Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

Peace of Heaven on a Hill
This Charming 2-Bedroom, 1 1/2 bath guest home is nestled on 4 acres right outside the city limits of Historic Hernando. Ideal for couples or small families, this home offers the perfect escape. Featuring an open concept kitchen/living space & a large master BR w/ an elegant bath suite. Enjoy time outdoors watching tv, relaxing on the porch swing, cooking on the grill, or gathering around the fire pit for s'mores. This home is located 10 miles from Snowden Grove & 1 Mile from Bolin Grove Farms

Close to Memphis NOT IN Memphis
Welcome to the Charleston Charmer. It is a peaceful centrally-located home. Nashville or Little Rock 3 hours. Interstate 55 2 miles. Graceland 15 minutes. Downtown Memphis 20 minutes (Grizzlies, Redbirds, Orpheum, FedEx Forum). Baptist Hospital 3 miles. Snowden Grove 7 miles. Enjoy all amenities of the city without the hustle and bustle. Minutes from restaurants, malls and shopping. Completely renovated inside. Private lock, dedicated workspace and large TV in all bedrooms. Come stay with us!

Four Bedroom Home - King Bed - Full Kitchen
Beautiful Colonial home perfect for up to 8 guests. Complete with four bedrooms, two and a half baths, master bedroom has its own private bathroom, a two-car garage, full kitchen, appliances, washer and dryer, wi-fi, TV, and security system -- all to yourself. Very quiet and peaceful – centered on the historic Hernando Square. Relax and spend your day with free access to the nearby Hernando Golf & Racquet Club as part of your stay with dinning, swimming pool, golf and tennis available.

3BD/2BA Home w/ 2-Car Garage & Private Backyard
The Space • Smart TVs in the living room and owner suite • Enclosed backyard with patio set • Fully stocked kitchen • Smart washer and dryer • Central AC and heating • 2-car garage plus driveway parking • Keyless entry • Super-fast WiFi • Dedicated workspace Sleeping Arrangements • King bed in owner suite • Queen beds in other bedrooms Additional Features • Owner suite with soaking tub and shower • Dining room • Reclining couch • Exterior security system

Pleasant Hill Estate
Welcome to our unique and stylish home, nestled in a serene environment. With thoughtful amenities & a warm ambiance, you’ll never regret choosing to stay here. The property features elegant architectural design with natural stones, providing a harmonious blend of elegance and natural beauty. The well-maintained exterior, with a beautiful lake and inviting landscaping, adds to the overall appeal of the 8-acre land with oak and magnolia trees. Book your unforgettable experience today!

Escape to Green T Lake Retreat
Bring the family to this great place with lots of room for fun. Tucked away from the hustle and bustle - in the heart of Hernando, but minutes from everything - is Green T Lake Retreat. A quiet place to slow down, relax and recharge. Come sit awhile on the wraparound porch that overlooks the lake while you catch a sunset or snuggle up with a book. Looking for more action? Spend some time inside battling it out on the arcade or playing your favorite games.

Memphis/Southaven One bedroom Nest
Perfect for traveling nurses, Doctors, workers, insurance claims OR long stay or short stay peaceful and centrally-located place. Close to hospitals, University college, Delta College, Graceland, Beal Street, Snowden Grove Baseball Complex, Landers Stadium & Arena, Memphis Airport, Casino, Church, Walmart, Hospitals, Sam’s, Eating Places Spacious and very quiet one bedroom, full kitchen with washer and dryer, salon bath. Pet welcome.

Casa de Magnolia Townhome near Tanger Outlet Mall
Casa de Magnolia is conveniently located in North Mississippi! A stones throw to Graceland, Home of Elvis, Tanger Outlet Mall, Casinos, and all things Memphis and Mid South. This beautifully decorated two-bedroom, 2 ½ bath home is perfect for families or friends looking to relax and unwind. Casa de Magnolia is perfect for families. She is first class all the way. Casa de Magnolia has everything you need for a restful stay.

Spacious Cottage in Silo Square
Kick back and relax in this calm, stylish space! This beautiful new construction home is located in the heart of the Snowden District in Southaven, MS. Conveniently located near the Silo Square, Bank Plus Amphitheatre, Landers Center, Snowden Grove Park, Target, Tanger Outlets, local restaurants, grocery shopping, parks, hospital, schools, and many more! A perfect place to stay for vacation, work, visiting family, etc.

Pocketful of Sunshine
Enjoy a stylish experience at this centrally-located house. Close to the Tanger Outlet Mall, Southaven Town Center, Tons of restaurants. Only 9 Miles from the Memphis International Airport, 11 Miles from Graceland, 17 Miles from Beale Street. Two Bedrooms, Two Baths with all the amenities of home. Come and enjoy your private home away from home.

Relaxing Row House in Downtown Hernando
Enjoy this relaxing 2-bedroom 2-bathroom house in walking distance to restaurants, bars, and boutiques for shopping. This relaxing home is located in downtown Hernando, Mississippi. With less than a 30 minute drive to Memphis, a 10 minute drive to Southaven, and less than an hour to Oxford, this location offers various day trip opportunities!
Popular amenities for DeSoto County house rentals
House rentals with a pool

Private Luxury-Crestmere Escape

Family Friendly home near Graceland

Classic Central Memphis Home

2 BR Townhouse near South Main w/private garage

Cori's Pool House

Mini-Golf ~ Heated Pool ~ Hot Tub ~ Game Room

Spacious home in quiet community

Stay, Swim, Unwind, & Enjoy!
Weekly house rentals

The Hamilton House - Entire House - Rare Find

The Vacation Home That’s Close To It All! 2

Quaint & Quiet Southaven Home

Charming 4BR Home with Private Pool & Cozy Appeal

Newly constructed, “award winning,” cozy home

18 Mi to Dtwn Memphis: Oasis on 8 Acres!

Cheerful 4 Bedroom with indoor fireplce

KING Bed -3 BD 3 Bth Spacious Hidden Gem!
Private house rentals

perfect place for Travelers

The Lakehouse Lodge & Retreat

Southaven Villa Park. New build home.

center of southaven home

Elegant Country Retreat

Pickleball House at Bonne Terre

The Hideaway at Horseshoe Lake

Family & Pet Friendly - Backyard - Patio
Destinations to explore
- Rentals with a patio DeSoto County
- Rentals with a fireplace DeSoto County
- Rentals with outdoor seating DeSoto County
- Hotel rentals DeSoto County
- Rentals with pools DeSoto County
- Pet-friendly rentals DeSoto County
- Fitness-friendly rentals DeSoto County
- Rentals with a washer and dryer DeSoto County
- Rentals with a fire pit DeSoto County
- Rentals with lake access DeSoto County
- House rentals Mississippi
- House rentals United States
- FedExForum
- Overton Park
- Shelby Farms Park
- Memphis Zoo
- Memphis Botanic Garden
- Orpheum Theatre
- Spring Creek Ranch
- Village Creek State Park
- Mississippi River State Park
- The Ridges at Village Creek
- de terra Vineyard & Wines of Somerville
- Stax Museum of American Soul Music
- Old Millington Winery
- National Civil Rights Muesum
- Memphis Country Club