
Family-friendly vacation rentals in DeSoto County
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in DeSoto County
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

DeerRun:Hidden Gem with Woods,Wildlife,and Gardens
We have 2 airbnbs at Deer Run that are close to Memphis,TN, I-55, restaurants and dining, great views. The spacious, 750+ sq ft cottage on 10 acres is good for retiree, couple, solo and business travelers alike. We look forward to sharing our property in this semi-secluded setting. Come relax in the comfy 12 inch deep foam mattress with super soft sheets. Enjoy the splendor of the woods, wildlife and gardens. We are far enough off the road that you will not see the street. Wheelchair accessible.

Hernando Hideaway (Entire Lakehouse)
Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

Peace of Heaven on a Hill
This Charming 2-Bedroom, 1 1/2 bath guest home is nestled on 4 acres right outside the city limits of Historic Hernando. Ideal for couples or small families, this home offers the perfect escape. Featuring an open concept kitchen/living space & a large master BR w/ an elegant bath suite. Enjoy time outdoors watching tv, relaxing on the porch swing, cooking on the grill, or gathering around the fire pit for s'mores. This home is located 10 miles from Snowden Grove & 1 Mile from Bolin Grove Farms

Wynnewood - Odell Cottage
Country get-away! Only 30 Minutes from Downtown Memphis, TN, yet out in the country on a 62 acre estate. Nature trails through the property allow for beautiful, peaceful strolls. We have fishing (in season). **** This cottage is set back in the woods and there is not a TV in this unit but there is Wifi. We have created a serene and unplugged experience. We have the "Wynnewood Elizabeth Cottage" and the "Wynnewood Jettie Jewel cottage" on our property that are listed separately.

3BD/2BA Home w/ 2-Car Garage & Private Backyard
The Space • Smart TVs in the living room and owner suite • Enclosed backyard with patio set • Fully stocked kitchen • Smart washer and dryer • Central AC and heating • 2-car garage plus driveway parking • Keyless entry • Super-fast WiFi • Dedicated workspace Sleeping Arrangements • King bed in owner suite • Queen beds in other bedrooms Additional Features • Owner suite with soaking tub and shower • Dining room • Reclining couch • Exterior security system

Horse Farm Hideaway
Industrial farmhouse style meets southern charm on an idyllic horse boarding family farm safely outside of Memphis. Perfect location both for sightseeing in Memphis or bypassing the city entirely. Take a walk among the horses to decompress. Full kitchen and a large bathroom. No exterior windows. Guests sleep well in our quiet and private space. Due to safety concerns, no children under 12. Locals or those without prior positive reviews will be rejected. Our property is smoke free.

Guesthouse 1 bed, beautiful views NO cleaning fees
Adorable 1 bedroom quite hide-a-way, but still have the convenience of being located close to everything. There are beautiful views from the front covered porch. NO PARTIES! Located about 20 minutes from Memphis and Tunica Casino Strip. Enjoy local attractions: Hernando Town Square, Snowden Grove, Shopping, Graceland, Memphis Botanic Gardens, Museums and Beale Street. This area and home is made for family life, not for the party style, come and enjoy your tranquil stay with us.

Your Stay at The Top of Mississippi
*Stylish Renovated Townhome in Southaven, MS* - Features 2 bedrooms, each with its own vanity. Primary bedroom with king bed, the second bedroom features two full-size beds. - Free wifi, fully equipped kitchen, washer and dryer. - Situated just 12 minutes from Memphis Airport, 20 minutes from downtown Memphis, and only minutes from local restaurants and parks. Plus, it’s only 5 minutes from the local hospital, making it a great choice for medical professionals or visitors. -No smoking

Cozy 2 Bedroom Guesthouse in a Relaxing Setting
Our two bedroom, two bath guesthouse is the perfect get-a-way from it all, yet close enough to everything you're looking to do: 3 minutes to the historic Hernando Town Square, 10 minutes to the MS River Delta and Historic Hwy 61, 12 minutes to Tanger Outlets & Landers Center in Southaven, 20 minutes to Snowden Grove Ballfields & Amphitheatre in Southaven, 23 minutes to Tunica Casino Strip, 25 minutes to Midtown/Downtown Memphis, 1 hour to Oxford, MS and 1 hour to Clarksdale, MS.

Three Bedroom Home - King Bed - Full Kitchen
Beautiful Colonial home perfect for up to 6 guests. Complete with three bedrooms, three and a half baths, master bedroom has its own private bathroom, full kitchen, appliances, washer and dryer, wi-fi, TV, and security system -- all to yourself. Very quiet and peaceful – centered on the historic Hernando Square. Relax and spend your day with free access to the nearby Hernando Golf & Racquet Club as part of your stay with dinning, swimming pool, golf and tennis available.

ELVIS Themed! Grazeland Vintage Airstream Farmstay
This Vintage Airstream has been fully renovated to bring it back to its former glory! There’s a full size bed and memory foam futon to accommodate 4. We have a gas cooktop, air fry microwave oven combo and outdoor gas grill to prepare perfect camping meals. We have 2 tvs inside and 1 outside. There’s an awesome sound system to listen to your favorite tunes. The best part of this Glamping experience is the beautiful outdoor bathing space perfect for relaxing!

The Tanger 1 Townhome
Hello Wonderful Guest This property is in a HOA Neighborhood and is geared more towards families and those visiting for work. If you are looking for a place that is quiet and you want to cozy up and hide out while visiting the near by cities this is also a place for you. Late traffic, parties, and gathering are prohibited in the neighborhood.LONG TERM BOOKINGS ASK ABOUT DISCOUNT !!!!!!!!!! ARE WELCOME! YOU WILL LOVE YOUR STAY HERE
Popular amenities for DeSoto County family-friendly rentals
Family-friendly home rentals with a hot tub

Roseleigh Villa Near (Silo-Square)

Southern Charm near Silo Square

Modern New House In Silo Square

Southaven Villa Park. New build home.

Whispering Winds! (Hot Tub and Pool)

Spacious home close to everything in Southaven

3 BR /1 BA - Southaven+ Abundant Parking UNIT A

Spacious home in Southaven.
Family- and pet-friendly home rentals

Green River Place Guest House

Cozy Cottage in Horseshoe Lake

Old Towne Ivy Farmhouse at Olive Branch

Suburban Comfort - 7 minutes from Silo Square!

Two story home in a cozy cove

Stylish & Cozy~5 min to Landers CTR+ Fenced Yard!

Studio Downtown! Clean, great location, sleeps 4!

Southaven Hideaway near Shopping
Family-friendly home rentals with a pool

8-Bedroom Estate with Pool & Panoramic Lake View

Private Hotel room 29

4BR /2.50 Brick Home - Close to Everything

The Lakehouse Lodge & Retreat

Premium Loft Cabin

Private & Spacious Lakefront Home in Memphis!

Private Pool House at Bethel Gardens -Olive Branch

18 Mi to Dtwn Memphis: Oasis on 8 Acres!
Destinations to explore
- Rentals with a fireplace DeSoto County
- Rentals with a fire pit DeSoto County
- Pet-friendly rentals DeSoto County
- Rentals with outdoor seating DeSoto County
- Rentals with lake access DeSoto County
- Hotel rooms DeSoto County
- Rentals with pools DeSoto County
- House rentals DeSoto County
- Family-friendly rentals Mississippi
- Family-friendly rentals United States
- FedExForum
- Overton Park
- Memphis Zoo
- Shelby Farms Park
- Orpheum Theatre
- University of Mississippi
- Village Creek State Park
- Stax Museum of American Soul Music
- National Civil Rights Muesum
- University of Memphis
- Simmons Bank Liberty Stadium
- Meeman-Shelby Forest State Park
- St. Jude Children's Research Hospital
- Graceland
- Rock'n'Soul Museum
- Autozone Park
- Children's Museum of Memphis-North
- Memphis Riverboats
- Graceland Mansion
- Rowan Oak
- Lee Park




