
Family-friendly vacation rentals in DeSoto County
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in DeSoto County
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

DeerRun:Hidden Gem with Woods,Wildlife,and Gardens
We have 2 airbnbs at Deer Run that are close to Memphis,TN, I-55, restaurants and dining, great views. The spacious, 750+ sq ft cottage on 10 acres is good for retiree, couple, solo and business travelers alike. We look forward to sharing our property in this semi-secluded setting. Come relax in the comfy 12 inch deep foam mattress with super soft sheets. Enjoy the splendor of the woods, wildlife and gardens. We are far enough off the road that you will not see the street. Wheelchair accessible.

Victorian Hernando Home ~ 25 Miles to Memphis
Escape the hustle and bustle of city life and head to the quaint town of Hernando for a stay at this eclectic 4-bedroom, 3.5-bath home! Complete with a pool table, an office, and a spacious yard, this vacation rental is a blast for the whole crew! Venture to Memphis to check out the live music scene, brush up on your rock ‘n’ roll history, or visit Greenbelt Park. Then, return to this fantastic home to sip an adult beverage on the back patio or cozy up with a family favorite in the home theater!

Forked Creek Retreat
Spacious 3 bed/2 bath, is located in the heart of Hernando. Only 2 mins to the beautiful downtown square, restaurants, shopping and only 5 minutes to the Interstate . Covered Patio. Open floor plan, large living room . Kitchen is fully stocked. Living Room/couch, recliner, 50" smart tv, wifi/Internet. Kitchen/Dining room seats 12. Master bedroom, queen bed, large on-suite, jetted tub, shower, large closet, toilet room, Bedroom 1/queen bed Bedroom 2/queen bed, 2nd bathroom/tub/shower combo.

Hernando Hideaway (Entire Lakehouse)
Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

Wynnewood - Odell Cottage
Country get-away! Only 30 Minutes from Downtown Memphis, TN, yet out in the country on a 62 acre estate. Nature trails through the property allow for beautiful, peaceful strolls. We have fishing (in season). **** This cottage is set back in the woods and there is not a TV in this unit but there is Wifi. We have created a serene and unplugged experience. We have the "Wynnewood Elizabeth Cottage" and the "Wynnewood Jettie Jewel cottage" on our property that are listed separately.

Guesthouse 1 bed, beautiful views NO cleaning fees
Adorable 1 bedroom quite hide-a-way, but still have the convenience of being located close to everything. There are beautiful views from the front covered porch. NO PARTIES! Located about 20 minutes from Memphis and Tunica Casino Strip. Enjoy local attractions: Hernando Town Square, Snowden Grove, Shopping, Graceland, Memphis Botanic Gardens, Museums and Beale Street. This area and home is made for family life, not for the party style, come and enjoy your tranquil stay with us.

Cozy 2 Bedroom Guesthouse in a Relaxing Setting
Our two bedroom, two bath guesthouse is the perfect get-a-way from it all, yet close enough to everything you're looking to do: 3 minutes to the historic Hernando Town Square, 10 minutes to the MS River Delta and Historic Hwy 61, 12 minutes to Tanger Outlets & Landers Center in Southaven, 20 minutes to Snowden Grove Ballfields & Amphitheatre in Southaven, 23 minutes to Tunica Casino Strip, 25 minutes to Midtown/Downtown Memphis, 1 hour to Oxford, MS and 1 hour to Clarksdale, MS.

ELVIS Themed! Grazeland Vintage Airstream Farmstay
This Vintage Airstream has been fully renovated to bring it back to its former glory! There’s a full size bed and memory foam futon to accommodate 4. We have a gas cooktop, air fry microwave oven combo and outdoor gas grill to prepare perfect camping meals. We have 2 tvs inside and 1 outside. There’s an awesome sound system to listen to your favorite tunes. The best part of this Glamping experience is the beautiful outdoor bathing space perfect for relaxing!

The Pony
-Boasting a small hoofprint of 128 square feet with a loft. Ideally situated in a safe area for those visiting/passing through Memphis. -Tranquil views of open fields, horses, and a variety of other furry friends at a working horse boarding barn. -Stay solo or with someone you don't mind cozying up to. Ideal for mobile guests comfortable with stairs and tighter spaces. Locals or those without positive reviews will be rejected. Our property is non smoking.

The Tanger 1 Townhome
Hello Wonderful Guest This property is in a HOA Neighborhood and is geared more towards families and those visiting for work. If you are looking for a place that is quiet and you want to cozy up and hide out while visiting the near by cities this is also a place for you. Late traffic, parties, and gathering are prohibited in the neighborhood.LONG TERM BOOKINGS ASK ABOUT DISCOUNT !!!!!!!!!! ARE WELCOME! YOU WILL LOVE YOUR STAY HERE

Brambles Home #1
Whether you're traveling for business or visiting family and friends, this stylish and family-friendly home provides the perfect blend of comfort and relaxation. Conveniently located near restaurants, grocery stores, public parks, the convention center, shopping malls, casino resorts, and more, you'll have everything you need just minutes away.

Cozy 2-Bedroom Home in downtown Hernando
Enjoy this cozy 2-bedroom 2-bathroom house in walking distance to restaurants, bars, and boutiques for shopping. This cozy home is located in the town of Hernando, Mississippi. With less than a 30 minute drive to Memphis , a 10 minute drive to Southaven, and less than an hour to Oxford, this location offers various day trip opportunities!
Popular amenities for DeSoto County family-friendly rentals
Family-friendly home rentals with a hot tub

Roseleigh Villa Near (Silo-Square)

Southern Charm near Silo Square

Southaven Villa Park. New build home.

Whispering Winds! (Hot Tub and Pool)

Spacious home close to everything in Southaven

Spacious home in Southaven.

Cozy 4BR 2BA Southaven Home

Magnolia Blue - Hot tub, Fire Pit, Pool Table
Family- and pet-friendly home rentals

Green River Place Guest House

Old Towne Ivy Farmhouse at Olive Branch

Memphis/Southaven Close to Everything

Peace of Heaven on a Hill

Stylish & Cozy~5 min to Landers CTR+ Fenced Yard!

Paradise cove

Studio Downtown! Clean, great location, sleeps 4!

Your Stay at The Top of Mississippi
Family-friendly home rentals with a pool

Private Hotel room 29

4BR /2.5 -7 Beds Sleep In Olive Branch

The Lakehouse Lodge & Retreat

Monthly-8 BR Estate with Pool Panoramic Lake View

Private Pool House at Bethel Gardens -Olive Branch

Cori's Pool House

Country Cottage

Elite 3.3-Acre Estate: Pro Kitchen & Pool Views
Destinations to explore
- Rentals with lake access DeSoto County
- Pet-friendly rentals DeSoto County
- Hotel rooms DeSoto County
- Rentals with pools DeSoto County
- Rentals with a fireplace DeSoto County
- House rentals DeSoto County
- Rentals with a fire pit DeSoto County
- Rentals with outdoor seating DeSoto County
- Family-friendly rentals Mississippi
- Family-friendly rentals United States
- FedExForum
- Memphis Zoo
- Overton Park
- Shelby Farms Park
- Orpheum Theatre
- Village Creek State Park
- Stax Museum of American Soul Music
- St. Jude Children's Research Hospital
- National Civil Rights Muesum
- Graceland
- Simmons Bank Liberty Stadium
- University of Mississippi
- Autozone Park
- Graceland Mansion
- Rock'n'Soul Museum
- Lee Park
- Meeman-Shelby Forest State Park
- University of Memphis
- Rowan Oak
- Children's Museum of Memphis-North




