Vacation rentals in DeSoto County

4.86 out of 5 average rating, 237 reviews

Hernando Hideaway (Entire Lakehouse)

Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

5 out of 5 average rating, 13 reviews

Peace of Heaven on a Hill

This Charming 2-Bedroom, 1 1/2 bath guest home is nestled on 4 acres right outside the city limits of Historic Hernando. Ideal for couples or small families, this home offers the perfect escape. Featuring an open concept kitchen/living space & a large master BR w/ an elegant bath suite. Enjoy time outdoors watching tv, relaxing on the porch swing, cooking on the grill, or gathering around the fire pit for s'mores. This home is located 10 miles from Snowden Grove & 1 Mile from Bolin Grove Farms

4.99 out of 5 average rating, 207 reviews

Guesthouse in Hernando

Guesthouse 1 bed, beautiful views NO cleaning fees

Adorable 1 bedroom quite hide-a-way, but still have the convenience of being located close to everything. There are beautiful views from the front covered porch. NO PARTIES! Located about 20 minutes from Memphis and Tunica Casino Strip. Enjoy local attractions: Hernando Town Square, Snowden Grove, Shopping, Graceland, Memphis Botanic Gardens, Museums and Beale Street. This area and home is made for family life, not for the party style, come and enjoy your tranquil stay with us.

5 out of 5 average rating, 28 reviews

Home in Southaven

Your Stay at The Top of Mississippi

*Stylish Renovated Townhome in Southaven, MS* - Features 2 bedrooms, each with its own vanity. Primary bedroom with king bed, the second bedroom features two full-size beds. - Free wifi, fully equipped kitchen, washer and dryer. - Situated just 12 minutes from Memphis Airport, 20 minutes from downtown Memphis, and only minutes from local restaurants and parks. Plus, it’s only 5 minutes from the local hospital, making it a great choice for medical professionals or visitors. -No smoking

4.94 out of 5 average rating, 35 reviews

Home in Olive Branch

Pleasant Hill Estate

Welcome to our unique and stylish home, nestled in a serene environment. With thoughtful amenities & a warm ambiance, you’ll never regret choosing to stay here. The property features elegant architectural design with natural stones, providing a harmonious blend of elegance and natural beauty. The well-maintained exterior, with a beautiful lake and inviting landscaping, adds to the overall appeal of the 8-acre land with oak and magnolia trees. Book your unforgettable experience today!

4.85 out of 5 average rating, 26 reviews

Home in Southaven

Family Getaway Home

Bring the family to enjoy. We offer lots of room for you to enjoy during your stay. 4 bedrooms with one of them having a full size air hockey table. Home offers a covered patio to sit and enjoy as well. Home is located in a nice quiet cove in the heart of DeSoto County. This home is convenient to lots of great restaurants and things to do. Downtown Memphis is a short 25 minute drive as well , home of the Memphis Tigers. Come , relax , and enjoy . Note - This is a nonsmoking home 😊

5 out of 5 average rating, 45 reviews

The Hamilton House - Entire House - Rare Find

Your family will be close to everything when you stay at this centrally-located establishment. Not only is this home cozy, it also has so many unique features that everyone will love. Conveniently Located: Hernando Historic Square- 5 Minutes Tanger Outlets/Landers Center- 15 Minutes Snowden Grove/Silo Square- 20 Minutes Northwest Community College- 20 Minutes Memphis Airport- 25 Minutes Fedex Forum/Autozone Park- 30 Minutes Oxford, MS - 1 Hour Clarksdale, MS- 1 Hour 10 Minutes

4.99 out of 5 average rating, 123 reviews

Guesthouse in Hernando

Cozy 2 Bedroom Guesthouse in a Relaxing Setting

Our two bedroom, two bath guesthouse is the perfect get-a-way from it all, yet close enough to everything you're looking to do: 3 minutes to the historic Hernando Town Square, 10 minutes to the MS River Delta and Historic Hwy 61, 12 minutes to Tanger Outlets & Landers Center in Southaven, 20 minutes to Snowden Grove Ballfields & Amphitheatre in Southaven, 23 minutes to Tunica Casino Strip, 25 minutes to Midtown/Downtown Memphis, 1 hour to Oxford, MS and 1 hour to Clarksdale, MS.

4.99 out of 5 average rating, 115 reviews

Farm stay in Southaven

The Longhorn Tiny House: Farm Stay Near Memphis

Escape to The Longhorn House, a cozy tiny house on 38 acres of rolling hills near Memphis, TN. Explore the countryside, fish or canoe on Blue Haze Lake, and enjoy sunsets with grazing miniature Longhorns. Relax at the outdoor seating area, grill out, or watch a movie under the stars at our outdoor theater. Inside, enjoy memory foam bedding, TVs, records, and board games. Just minutes from Memphis and Graceland, this is your perfect escape to nature and comfort.

Guesthouse in DeSoto County

4.91 out of 5 average rating, 70 reviews

Bonne Terre Cottage Room

Relaxing private upstairs room in a building to yourself. Located in Nesbit, MS: Fantastic stay for the Blues Trail, Memphis, Oxford, or Snowden Grove *20 min from downtown Memphis, Memphis Airport, and Graceland* Perfect spot right outside the city to feel safe and secluded. This room is the UPSTAIRS of our cottage that has it's own private entrance. The downstairs is not used as a room, so no need to worry about sound.