Guesthouse vacation rentals in Colleton County
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Top-rated guesthouse rentals in Colleton County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Colleton County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Beaufort
4.94 out of 5 average rating, 230 reviewsCozy private guest house
Guesthouse in Beaufort
4.94 out of 5 average rating, 396 reviewsMeridian Rd. Guest House Walk to Restaurants/Parks
Guesthouse in Ridgeville
4.82 out of 5 average rating, 213 reviewsPond House Bungalow at Natural Gathering Grounds
Guesthouse in Beaufort
4.98 out of 5 average rating, 361 reviewsThe Wren Guest House
Guest house rentals with a patio
Guesthouse in Beaufort
4.64 out of 5 average rating, 42 reviewsWaterfront! Guest House!
Guesthouse in Ridgeville
4.9 out of 5 average rating, 30 reviewsCute Frog
Guesthouse in Seabrook
5.0 out of 5 average rating, 45 reviewsAdorable guesthouse outside Beaufort
Guesthouse in Summerville
4.98 out of 5 average rating, 52 reviewsHearts & Dreams Peaceful Family Retreat w/ pool
Guesthouse in Saint George
4.96 out of 5 average rating, 55 reviewsSimmons Sweet Suite
Guest house rentals with a washer and dryer
Guesthouse in Beaufort
4.8 out of 5 average rating, 186 reviewsSanctuary Cottage- Social Distancing Destination
Guesthouse in Beaufort
4.98 out of 5 average rating, 361 reviewsThe Wren Guest House
Guesthouse in Beaufort
4.98 out of 5 average rating, 204 reviewsBuddy's Cottage near everything in Beaufort, SC
Guesthouse in Beaufort
4.88 out of 5 average rating, 111 reviewsParadise Blue, bright, airy carriage house in town
Guesthouse in Beaufort
4.64 out of 5 average rating, 22 reviewsCozy Pet Friendly 1/1 Guest House + Shared Yard
Guesthouse in Summerville
4.87 out of 5 average rating, 30 reviews1 Bed Detached Guest House, No Smokers, No Animals
Guesthouse in Summerville
4.98 out of 5 average rating, 52 reviewsHearts & Dreams Peaceful Family Retreat w/ pool
Guesthouse in Beaufort
5.0 out of 5 average rating, 59 reviewsLow-country Carriage House
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