Guesthouse vacation rentals in Berkeley County

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Berkeley County guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
Guesthouse in Summerville
4.88 out of 5 average rating, 805 reviews

New Loft in Historic Summerville

LauraRating, 5 stars2 days ago
The stay was great! WiFi was a little spotty - only relevant if you were planning on working from the space. Everything else was great and Jacquelynn was an excellent host
Guesthouse in Charleston
4.76 out of 5 average rating, 104 reviews

Exclusive, safe, quiet island living Charleston!

SarahRating, 5 stars4 months ago
I travel a lot for work. I always look for peaceful places that feel safe and have beautiful surroundings (in the event that I get to enjoy them on a work trip). Mo was a clear and responsive host. Parking is so easy in this neighborhood. The space is even more spacious in person than I expected. Thanks, Mo!
Guesthouse in Hanahan
4.73 out of 5 average rating, 163 reviews

Cozy Studio with 14% weekend discounts

RobertRating, 5 stars3 weeks ago
Christopher was an amazing host. Everything about check in and our stay was well laid out and informative. The house was clean and suited our needs perfect. 20-25 minutes from everything we had planned on doing. We can’t wait to book again!
Guest favorite
Guesthouse in Mount Pleasant
4.94 out of 5 average rating, 256 reviews

Green Garden Studio @greengardenstudio2017

HelenRating, 5 stars1 month ago
This was the cutest above garage studio. It is very well done, clean and comfortable. The property is very well maintained- we would definitely stay here again! The AC was not working properly when we arrived but Holly responded immediately and got it working. Highly recommend!!

Guest house rentals with a patio

Top guest favorite
Private room in Summerville
5 out of 5 average rating, 38 reviews

Garden View Cottage

KristenRating, 5 stars1 day ago
Excellent stay. Wish we could’ve explored Summerville more! Great location and was a wonderful stay!
Top guest favorite
Guesthouse in Goose Creek
5 out of 5 average rating, 40 reviews

Dreams

ChristineRating, 5 stars2 weeks ago
Nice place to stay! Looks just like the pics! Clean and comfortable!
Guesthouse in Charleston
4.8 out of 5 average rating, 5 reviews

Historic plantations and gardens

KarenRating, 5 stars1 week ago
Marielas place was exactly as listed. And you couldn't ask for a more thoughtful host. Although we were basically only there to sleep, she and her son went above and beyond to make our 2 days their quite pleasant.
Superhost
Guesthouse in Charleston
5 out of 5 average rating, 4 reviews

Stylish Carriage House in Charleston

FaithRating, 5 stars3 weeks ago
Jessie and Robin were Great Host! A couple of problems came up that was unexpected and they were very quick to help fix the problems! Definitely will be staying in one of their places again! Great people!
Top guest favorite
Guesthouse in Summerville
5 out of 5 average rating, 41 reviews

2 King beds 2 Bath*Gardens* Walkable Summerville

DywannaRating, 5 stars1 week ago
The Chesterfield Cottage is even more beautiful in person! My best friend & I brought our husbands for a Father’s Day getaway & everything was perfect. The garden is peaceful with flowers, birds & a waterfall. We enjoyed meals outside under the covered table & used the coffee bean grinder/tea setup & vintage-style turntable. Each bedroom has a private bath, ideal for couples. We loved playing cards outside in the evening & had breakfast & coffee on the upstairs patio. Joe and Kristen thought of everything! Plenty of towels, games, linens. Their welcome manual was so helpful, and Isle of Palms Beach was a great local tip. Can’t wait to return! ,-Dywanna, Tiff, Chawne & Dale
Top guest favorite
Guesthouse in Summerville
4.99 out of 5 average rating, 77 reviews

Hearts & Dreams Peaceful Family Retreat w/ pool

PatRating, 5 stars1 day ago
You will love staying here! Calm,peacefully and beautiful!! It's country yet it's easy to get to all nice places to eat and awesome sites! Friendly goats and chickens to visit we plan to visit again.
Guest favorite
Guesthouse in Ridgeville
4.9 out of 5 average rating, 82 reviews

Cute Frog

JessicaRating, 5 stars1 week ago
Darlene, thank you for the lovely stay! See you again soon! :)
Top guest favorite
Guesthouse in Charleston
5 out of 5 average rating, 12 reviews

Stylish Carriage House+Pool House

RebeccaRating, 5 stars1 week ago
We had the most amazing stay at this beautiful Airbnb in Charleston! We were in town for a wedding, and the location couldn’t have been more perfect for us. Even though there was some construction happening on the pool when we arrived, the property itself was absolutely stunning and felt like home the moment we walked in. It was just me, my mom, and my little sister, and we all felt incredibly safe and welcomed throughout our stay. Jessie, the host, was truly incredible—so friendly, thoughtful, and accommodating. One night when we’d return from being out, she and her sweet dog would greet us and make time for a quick chat, which made us feel like part of the family. On the morning we checked out, she and her husband were there to send us off with the same warmth we felt the entire trip. It’s rare to find such genuine hospitality, and we’re so grateful for the experience. Would absolutely stay here again!

Guest house rentals with a washer and dryer

Top guest favorite
Guesthouse in North Charleston
4.99 out of 5 average rating, 71 reviews

Old Village Park Circle

LillyRating, 5 stars1 month ago
This was one of the best places I’ve stayed!!! Being my first time visiting Charleston, Kc’s place was in the perfect area— right in the middle of everything. She is very quick to respond and has great suggestions! The home itself is exactly as listed, very clean, & has everything you could need. If you’re lucky, you’ll meet her cute pup too :). I’d recommend her place over and over! Will definitely be back!
Guest favorite
Guesthouse in Charleston
4.92 out of 5 average rating, 53 reviews

Cozy Coastal Loft

Brittany And JohnRating, 5 stars3 weeks ago
Daniel Island is beautiful and feels very safe. The studio was perfect for what we needed. Wish we were in town longer to check out the pools, etc, so maybe next trip. The studio was very clean, we loved the washer and drier feature as well as the dishwasher was handy. (Tip-the closet fits a pack and play perfectly, so baby still had a quiet and dark space)
Top guest favorite
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 253 reviews

Cozy Apartment in Mount Pleasant

TaylorRating, 5 stars4 weeks ago
Dorothy's stay was perfect! It's such a cozy apartment and had everything we needed and more. The neighborhood is beautiful and it was easy to get to downtown Charleston (~15 min away) and other locations via Uber/Lyft. She was so easy to communicate with and quick to respond. I'd highly recommend!
Guest favorite
Guesthouse in Summerville
4.91 out of 5 average rating, 45 reviews

Cute, Clean Detached Guest House

HeidiRating, 5 stars3 weeks ago
Very nice place! I will come back!
Guesthouse in Summerville
4.73 out of 5 average rating, 15 reviews

Guest House at Private Estate

KylaRating, 5 stars3 weeks ago
Beautiful space tucked away from the highway and city. We loved the place and the green space around it. We will stay again!
Guest favorite
Guesthouse in Summerville
4.8 out of 5 average rating, 35 reviews

ELEGANT COTTAGE IN HISTORIC SUMMERVILLE

JasonRating, 5 stars2 weeks ago
Very spacious area. Loved that the kitchen was very well stocked with everything I needed to prepare my own meals and also had a dishwasher. Comfortable bed and plenty of room for everything I needed. Susan was very nice and helpful. Would stay here again if available on my future trips.
Top guest favorite
Guesthouse in Mount Pleasant
5 out of 5 average rating, 34 reviews

Completely furnished/private 1-bedroom guest house

BeverlyRating, 5 stars3 days ago
This is such a nice place. You walk in to the cleanest smell ever. The place was very clean and suited our short getaway. It is centrally located so getting to the areas we wanted to see was a breeze. Very nice quiet neighborhood/community. Check in and check out was extremely simple.
Guest favorite
Guesthouse in Summerville
4.89 out of 5 average rating, 75 reviews

Fripp Legare Cottage: cozy in historic Summerville

FranRating, 5 stars4 weeks ago
Thank you for sharing your lovely cottage with us. It was clean and we had everything we needed. It was small but quant and the beds were very comfortable. Loved the huge shower. We took lots of walks and enjoyed the scenery. It was close to downtown and the Saturday market was great. We will be back.

Destinations to explore