Guesthouse vacation rentals in Berkeley County

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Berkeley County guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
Guesthouse in Charleston
4.99 out of 5 average rating, 293 reviews

Spacious Daniel Island Apartment

NelleRating, 5 starstoday
We had a wonderful stay at David’s. The space was exactly what we were looking for - clean, quiet, and comfortable. Daniel Island is beautiful, and downtown Charleston and Mount Pleasant are both very accessible by car/Uber. David was very communicative and a great host - we would love to stay here again!
Guesthouse in Charleston
4.76 out of 5 average rating, 103 reviews

Exclusive, safe, quiet island living Charleston!

SarahRating, 5 stars2 months ago
I travel a lot for work. I always look for peaceful places that feel safe and have beautiful surroundings (in the event that I get to enjoy them on a work trip). Mo was a clear and responsive host. Parking is so easy in this neighborhood. The space is even more spacious in person than I expected. Thanks, Mo!
Guesthouse in Hanahan
4.74 out of 5 average rating, 160 reviews

Cozy Studio with 14% weekend discounts

DonnaRating, 5 stars2 weeks ago
Private, quiet and comfortable. If you’re not looking for fancy, this is your place. Very quiet and comfortable. I would stay again.
Top guest favorite
Guesthouse in North Charleston
5 out of 5 average rating, 153 reviews

The Park Circle Clerestory Studio Guest House

CatherineRating, 5 starstoday
We had a wonderful time at Clerestory Studio, a beautiful space built and designed by thoughtful hosts Dave and Catherine. The studio is spotless, beautifully decorated with art, music posters and big, beautiful plants. The bathroom boasts an amazing shower and little touches throughout to make you feel at home. The host binder offers solid recommendations if you want something to do, and there are plenty of places to just relax and enjoy the day. Walkable areas close to Park Circle and restaurants.
Top guest favorite
Guesthouse in Summerville
4.88 out of 5 average rating, 796 reviews

New Loft in Historic Summerville

AmyRating, 5 stars1 day ago
We loved our stay at Jacquelynn's! We had to travel with our two older, yet anxious, dogs for a wedding and it turned out to be the perfect place for us. The loft is detached from the home, making it much more private to go to and from. The place was spotless with cute decor. Even though it is a smaller space, she has everything you need to make your stay comfortable. Lots of towels and blankets as well as silverware, coffee pot, and mugs. I was pleasantly surprised at how the bathroom was actually quite spacious for the small space. The most important and best part for us was the peace and quiet. We typically have to worry about outside noise as our dogs will bark at any and every noise they hear. But the loft is nestled in such a quiet and quaint neighborhood, making it perfect for anyone with anxiety ridden dogs. I highly recommend Jacquelynn's loft!
Guest favorite
Guesthouse in North Charleston
4.93 out of 5 average rating, 394 reviews

Cozy Park Circle, Charleston Guest House

CaitlynRating, 5 stars1 month ago
Very convenient place to Park Circle and the major highways in Charleston.
Top guest favorite
Guesthouse in Summerville
4.98 out of 5 average rating, 696 reviews

★Delightful guest house near historic plantations★

ArthurRating, 5 stars3 weeks ago
What a beautiful place! Super friendly hosts, decor was stunning, felt right at home. Special details like a fresh baked loaf of bread with some jam and fresh eggs from the hosts own chickens made this a wonderful and unique experience. The swinging couch was a great place to chat about and unwind from the day. Every detail was thought through and appreciated. We will definitely look this host up on our next trip to Charleston. Thank you for a great experience.
Guest favorite
Guesthouse in Mount Pleasant
4.94 out of 5 average rating, 251 reviews

Green Garden Studio @greengardenstudio2017

ShawnRating, 5 stars2 weeks ago
My wife and I stayed here for a long weekend during my families wedding. Place was just what we were looking for. Would definitely stay here again if we visit Charleston again! Host was very responsive and even let me borrow their personal iron. 5 stars!!

Guest house rentals with a patio

Top guest favorite
Guesthouse in Goose Creek
5 out of 5 average rating, 34 reviews

Dreams

WendyRating, 5 starstoday
Lovely accommodation in a quiet neighborhood. The space was inviting, modern, clean, and comfortable. Just a quick 20 minute drive to downtown Charleston.
Top guest favorite
Guesthouse in Summerville
5 out of 5 average rating, 34 reviews

2 King beds 2 Bath*Gardens* Walkable Summerville

JennyRating, 5 stars5 days ago
Beautiful yard, nice furnishings and decor, clean and comfortable. Very safe and quiet. Very friendly hosts in house next door. Will definitely rent here again.
Top guest favorite
Guesthouse in Summerville
4.99 out of 5 average rating, 72 reviews

Hearts & Dreams Peaceful Family Retreat w/ pool

PaulaRating, 5 stars3 weeks ago
Welcoming, spacious, comfortable and everything you need. Enjoyed the natural, peaceful surroundings only a few minutes from historic Summerville. Perfect for our family of four with everyone having his/her own space. Easy drive to Charleston if timing is right. Holly is very responsive and helpful - much appreciated. :) Thank you for everything!!
Guest favorite
Guesthouse in Ridgeville
4.9 out of 5 average rating, 69 reviews

Cute Frog

JohnRating, 5 stars4 days ago
This frog was a super clean, easy to find great value for the area. Not walkable, but an easy short drive to anything needed. Good sized fridge with separate freezer that came in handy for cooler packs. Comfortable furniture and bedding just as described. Would recommend.😊
Guest favorite
Guesthouse in Charleston
5 out of 5 average rating, 5 reviews

Stylish Carriage House+Pool House

KylieRating, 5 stars2 weeks ago
Jessie & Robin were PHENOMENAL hosts. Our stay wasn’t long but it was peaceful, clean and just what we were looking for. The space was exactly as described. They were quick to respond and were proactive at check in and check out. Our time in Charleston was wonderful and the stay only added to that! If we find our way back to Charleston I will be booking with them again.
Guesthouse in Summerville
5 out of 5 average rating, 4 reviews

Southern Roost

SarahRating, 5 stars10 months ago
My family and I enjoyed staying here. Candice and her husband were great, checked in on us to make sure all needs were met. My daughters enjoyed feeding the chickens and playing with the goats and cats. Property peaceful and relaxing. We would totally stay here again.
Superhost
Guesthouse in Goose Creek
4.79 out of 5 average rating, 82 reviews

Cozy relaxing RV/Camper Goose Creek

GarnerRating, 5 stars2 months ago
Alfredo and Catalina were amazing to stay with! Quick response, easy booking, the area was clean and well taken care of! Would book again!
Guest favorite
Guesthouse in North Charleston
4.92 out of 5 average rating, 131 reviews

My Happy Place

BridgetRating, 5 starstoday
We loved our stay at the pool house! It had everything we needed and the location was great. I would highly recommend it!

Guest house rentals with a washer and dryer

Guest favorite
Guesthouse in Charleston
4.91 out of 5 average rating, 45 reviews

Cozy Coastal Loft

LisaRating, 5 stars1 week ago
Jeremiah’s place was perfect for our long wedding anniversary weekend. Everything that we needed for our stay was provided and it was super clean. It was very easy to get to this nice location and Jeremiah responded immediately when I sent him a message. The local restaurants were really good and we only had a short drive to downtown Charleston and Sullivan’s Island Beach. We would definitely stay here again.
Top guest favorite
Guesthouse in North Charleston
4.98 out of 5 average rating, 66 reviews

Old Village Park Circle

SusanRating, 5 stars2 weeks ago
We enjoyed our stay in KC’s cute garage apartment. It is quite artistically decorated. The place was spotlessly clean and everything was as described in the listing. It’s just a short walk to all the restaurants and shops in North Charleston. We would definitely stay there again.
Guest favorite
Guesthouse in Summerville
4.9 out of 5 average rating, 42 reviews

Cute, Clean Detached Guest House

ToddRating, 5 stars2 months ago
This is a great place to stay, clean and comfortable. New appliances and very well kept. High speed internet could work remotely and great TV. Location was nice, had a country feeling with woods in the back- saw deer at night. Highly recommend for a getaway for 1-2 people. Host was great, this was my first time using the app and I wasn’t familiar with all the functions, and they were helpful with check in process (I didn’t realize it was all well explained in the bottom tabs in the app). Will definitely be back!
Guest favorite
Guesthouse in Summerville
4.77 out of 5 average rating, 31 reviews

ELEGANT COTTAGE IN HISTORIC SUMMERVILLE

HeatherRating, 5 stars8 months ago
It was the most peaceful and relaxing experience I’ve had using Airbnb. Susan is an absolute “Delight” Thank you Susan,Watson,friends and family
Top guest favorite
Guesthouse in Mount Pleasant
5 out of 5 average rating, 29 reviews

Completely furnished/private 1-bedroom guest house

DennisRating, 5 stars3 weeks ago
We were really happy with Michelle's and Jim's place. It was perfect for our time at the Charleston Open on Daniel Island: very private & quiet, really comfortable and it had absolutely everything we'd want for a comfortable few days. The location was convenient to everything we planned on doing and we'd definitely stay there again.
Guest favorite
Guesthouse in Summerville
4.9 out of 5 average rating, 29 reviews

Elizabeth Arden Tuscany Style Cottage, Summerville

ElizabethRating, 5 stars8 months ago
We arrived as a tropical storm was affecting the local area with unusual flooding. We were offered an alternative cottage which was an up grade. that had less puddles to transverse without additional charges. Classic southern hospitality and kindness. Very lovely and welcoming stay.
Guest favorite
Guesthouse in Summerville
4.9 out of 5 average rating, 70 reviews

Fripp Legare Cottage: cozy in historic Summerville

DonnaRating, 5 stars2 months ago
I love the area of this cottage. The historic homes are such a treat to see. Access to the downtown square is convenient and getting to the major roadways was easy as well.
Top guest favorite
Guesthouse in Summerville
4.94 out of 5 average rating, 82 reviews

Summerville Country Guest Studio with washer/dryer

BritniRating, 5 stars2 days ago
Our stay was an absolute dream—peaceful, cozy, and just what we needed for a relaxing escape. The space was the perfect retreat, and the hosts were nothing short of wonderful—gracious, attentive, and always ready to help if we had any questions. From the moment we stepped through the front door and up into the lovely, spacious studio, we felt so welcomed. Waiting for us was the sweetest surprise: a thoughtfully prepared snack, blending sweet and salty treats with refreshing bottled water—exactly what we needed after a long day of travel. It’s those little thoughtful touches that truly make a place memorable. If we find ourselves back in the area, we’d be delighted to stay here again!

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