
House vacation rentals in Simpsonville
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Top-rated house rentals in Simpsonville
Guests agree: these houses are highly rated for location, cleanliness, and more.

Vintage home near downtown Greenville.
Cozy home with vintage look. Be in downtown Greenville or Paris Mt. State Park in under ten minutes. Close to shopping and the state Farmer's Market is a mile away. Acre yard gives spacious feeling. A complimentary Power Point of South Carolina and local history, culture, events, and business is available to help introduce you to one of the country's best kept secrets. Cut flowers and help yourself to our organic garden for use during your stay (seasonally). Small RV parking but no hook ups.

A Tranquil Place (near downtown Greenville)
A Tranquil Space is conveniently located close to Downtown Greenville. The large suite includes the bedroom, living area, kitchenette (fridge/freezer/convection oven), bathroom, and study/eating area. It is newly renovated area on the end of my home with a private entrance. The space is welcoming and inviting...a perfect space to get away from the hustle. Although minutes from Downtown, the suite feels like you're in the mountains with a private back yard and many trees. Enjoy your stay!

The Greenville Nest - Retreat & Relaxation Home
This beautifully one-level home offers 3 queen beds and 2 baths, accommodating up to 6 guests. Centrally located in a peaceful neighborhood. 8-minute drive to GSP airport, 15-minute drive to downtown Greenville, minutes from I-85/385, and minutes from Woodruff and Pelham Rd. You'll appreciate the easy access to food delivery and restaurants. Enjoy a stylish Experience for entertaining, working, and relaxing with high-speed Wi-Fi. Quiet and safe with an enjoyable private screened porch and Grill.

Fenced in Yard, 2 Queen Beds, Downtown!
Hard to beat this amazing value! Nestled on a quiet street 5 minutes from downtown, this 2bed/1bath property is perfect for your visit to Greenville. Each bedroom has a queen bed and plenty of closet space with hangers. Out back, there's a spacious deck to relax on, and the property has a fenced in yard which would be ideal for your curious furry friend. This property is minutes from hospitals & interstate 85. Ideal for work travelers, or simply curious visitors. There's a driveway for parking.

Spacious 4 BR Escape w/ Fenced Yard Near Downtown
Welcome to your stylish retreat, conveniently located just 3 minutes from the shopping & dining in charming Downtown Simpsonville & convenient to everything that Greenville has to offer. With 4 bedrooms, 2 full baths & a fenced in yard, this house has everything you need for your stay. Located in a safe & quiet neighborhood just 20 minutes from downtown Greenville & 5 minutes to all of your daily needs. <B>Traveling with a large group? Ask about our other 4BR house across the street!<B>

Spectacular home 1 mile from Main St Greenville!
Enjoy your stay in this charming up to date house 1 mile from Main St Greenville! Take a walk through the Historic Pinckney district on your way to Greenville’s museums, restaurants, theaters, and stunning Reedy River Falls Park. Easy access to the Swamp Rabbit biking and walking trail, and just 4 blocks from the upcoming Unity Park. House is located on quiet residential street with private driveway. Relax on rocking chairs on front porch or around a portable fire pit in large backyard.

Modern Farmhouse in Downtown Simpsonville, SC
Newly renovated two-bedroom home located in downtown Simpsonville, within easy walking distance of an excellent variety of restaurants, shops and places of interest. A spacious private balcony, leading off from the main bedroom suite overlooks a peaceful backyard... a great place to relax outdoors! The kitchen is fully equipped for preparing great meals. Our home is thoroughly and professionally cleaned & sanitized. ***Please note there is a train that runs midday and late at night.

Simpsonville Southern Comfort
Welcome to Simpsonville Southern Comfort! Our home offers a comfortable, completely remodeled space with all of the amenities of home to make your stay enjoyable. This home is in a GREAT location just a 5-minute drive from the conveniences of the Five Forks area, and a short 7-minute drive to the enjoyment of The Square in Downtown Simpsonville. Our home is also a quick 20-minute drive from GSP International Airport, and 20 minutes from Downtown Greenville. Enjoy your stay!

2 Living Spaces -2800 ft.²- Sleeps 10
This spacious split-level house is in a quiet neighborhood and has plenty of room for 10 guests. Enjoy a king bed in the master bedroom, and 3 additional bedrooms, each featuring a queen bed. 2 single trundle beds are also available for the little ones. This home has space to gather everyone together or spread out and have some quiet time. Some fun features of this home are an outdoor fire pit, pool table, fenced backyard, deck with grill, and 3 smart TVs. 4 bedroom 3 bath home.

Greenville Prime Location-Steps from Swamp Rabbit
You'll love the abundant natural light in this peaceful one bedroom retreat. We are located in the Pettigru Historic District and are just a 5 minute walk from Bon Secours Wellness Arena and a 15 minute walk to Main Street. This is an upstairs unit (1 of 3 total units located within the triplex) and has a private, exterior entrance. There's a kitchen with all the utensils, pots, bowls, plates, cups, etc. that you could need for your stay as well as a stocked Nespresso machine!

Greenville Modern Retreat - 8 minutes to Downtown
Decorated in a mid century modern theme, this home is perfect for couples and business travelers looking for a peaceful, modern aesthetic filled with natural light. This home is located in San Souci just 2.5 mi (8min drive) to downtown Greenville. It is also conveniently located 1/2 mi to the Swamp rabbit trail and the Swamp Rabbit Grocery. Please see “Where you’ll be” section for further description of location and the neighborhood. We're excited to have you join us!

Family & Pet Friendly Home - Sleeps 8
Our home is absolutely perfect for entertaining, work and relaxation. Enjoy fast wifi and free coffee. Connect over a meal at our spacious dining table. Families will love the large, fenced-in backyard, toys and board games in our huge rec room, complete with ping pong table! Quiet and easy connections to Greenville & Simpsonville. Only 5 mins from Discovery Island Waterpark. Community park and playground accessible with lots of space to roam with family or pets.
Popular amenities for Simpsonville house rentals
House rentals with a pool

Upstate Getaway at the Relaxing Ranch

Ultra CLEAN and COZY Home away from Home!

HOT TUB Sleeps 11 Gameroom Cozy Getaway

BICYCLE HAVEN

Spacious 4bdr house in a quiet neighborhood

Shalom House with Pool near DT Greer SC

Spacious 3 BR house with private backyard.

Near Downtown Greenville + Swamp Rabbit Trail
Weekly house rentals

Fully Furnished Cozy Cottage

The Green Cottage

The Westfield | Cozy Downtown Greer Retreat

Cute cozy house in a quiet secluded area.

Pet-Friendly 3BR Home- Fenced Yard- Fire Pit W/TV

Heart of Fountain Inn: 2BR Gem

Cozy Charming Townhome

Walk Downtown Simpsonville 3/1
Private house rentals

Cozy Cottage in Greenville

18 Hidden Gem - Private Home - 3 BDRM In 5 Forks

Scenic Simpsonville Studio

Downtown Simpsonville/5 Private Bedrooms/Pergola

Simple Circle Cottage - Quiet. Quaint. Close.

Rustic Ranch

Bright & Modern, Backyard+Firepit, Near Greenville

Spacious Home w/ Access
When is the best time to visit Simpsonville?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ474 | ﺩ.ﺇ459 | ﺩ.ﺇ448 | ﺩ.ﺇ444 | ﺩ.ﺇ466 | ﺩ.ﺇ466 | ﺩ.ﺇ437 | ﺩ.ﺇ470 | ﺩ.ﺇ455 | ﺩ.ﺇ470 | ﺩ.ﺇ415 | ﺩ.ﺇ463 |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 20°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
Quick stats about house rentals in Simpsonville

Total vacation rentals
Explore 80 vacation rentals in Simpsonville

Nightly prices starting at
Simpsonville vacation rentals start at ﺩ.ﺇ110 per night before taxes and fees

Verified guest reviews
Over 2,360 verified reviews to help you choose

Family-friendly vacation rentals
40 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
80 of Simpsonville vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Simpsonville rentals

4.8 Average rating
Simpsonville stays are highly rated by guests—averaging 4.8 out of 5!
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- Rentals with a fire pit Simpsonville
- Family-friendly rentals Simpsonville
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- Rentals with outdoor seating Simpsonville
- House rentals Greenville County
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- House rentals United States
- Gorges State Park
- Chimney Rock State Park
- Table Rock State Park
- Lake Lure Beach and Water Park
- Clemson University
- Jump Off Rock
- Tryon International Equestrian Center
- Carl Sandburg Home National Historic Site
- Saint Paul Mountain Vineyards
- Bon Secours Wellness Arena
- Burntshirt Vineyards
- Devils Fork State Park
- Overmountain Vineyards
- DuPont State Forest
- Falls Park On The Reedy
- Peace Center
- Paris Mountain State Park
- Fred W Symmes Chapel
- Jones Gap State Park
- Greenville Zoo
- Cleveland Park
- Frankies Fun Park
- Looking Glass Falls
- Oconee State Park




