House vacation rentals in Simpsonville

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Top-rated house rentals in Simpsonville

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Top guest favorite
A spacious living area features a comfortable sectional sofa and a recliner. Natural light enters through large windows, creating a welcoming environment. Framed artwork adorns the walls, complementing the warm tones of the room. A dining area is visible in the background.
Home in Taylors
4.98 out of 5 average rating, 234 reviews

Vintage home near downtown Greenville.

Cozy home with vintage look. Be in downtown Greenville or Paris Mt. State Park in under ten minutes. Close to shopping and the state Farmer's Market is a mile away. Acre yard gives spacious feeling. A complimentary Power Point of South Carolina and local history, culture, events, and business is available to help introduce you to one of the country's best kept secrets. Cut flowers and help yourself to our organic garden for use during your stay (seasonally). Small RV parking but no hook ups.

Top guest favorite
A welcoming entryway features a brick patio surrounded by trees, providing a natural setting. Two chairs and a small table sit on one side, with a cozy seating area visible. The home showcases large windows that allow for ample natural light.
Home in Greenville
4.98 out of 5 average rating, 212 reviews

A Tranquil Place (near downtown Greenville)

A Tranquil Space is conveniently located close to Downtown Greenville. The large suite includes the bedroom, living area, kitchenette (fridge/freezer/convection oven), bathroom, and study/eating area. It is newly renovated area on the end of my home with a private entrance. The space is welcoming and inviting...a perfect space to get away from the hustle. Although minutes from Downtown, the suite feels like you're in the mountains with a private back yard and many trees. Enjoy your stay!

Top guest favorite
A screened porch is highlighted, featuring comfortable wooden seating with light cushions and a matching table. Natural light is allowed through large windows and a skylight, providing a view of the surrounding greenery. A small potted plant decorates the table, enhancing the relaxing atmosphere.
Home in Greenville
4.96 out of 5 average rating, 142 reviews

The Greenville Nest - Retreat & Relaxation Home

This beautifully one-level home offers 3 queen beds and 2 baths, accommodating up to 6 guests. Centrally located in a peaceful neighborhood. 8-minute drive to GSP airport, 15-minute drive to downtown Greenville, minutes from I-85/385, and minutes from Woodruff and Pelham Rd. You'll appreciate the easy access to food delivery and restaurants. Enjoy a stylish Experience for entertaining, working, and relaxing with high-speed Wi-Fi. Quiet and safe with an enjoyable private screened porch and Grill.

Superhost
A cozy living area features a leather couch adorned with pink cushions, positioned near a decorative glass coffee table. Sunlight filters through the windows, illuminating a flat-screen television above a white mantel. A small side table and a bookshelf add functional charm to the space.
Home in Greenville
4.81 out of 5 average rating, 176 reviews

Fenced in Yard, 2 Queen Beds, Downtown!

Hard to beat this amazing value! Nestled on a quiet street 5 minutes from downtown, this 2bed/1bath property is perfect for your visit to Greenville. Each bedroom has a queen bed and plenty of closet space with hangers. Out back, there's a spacious deck to relax on, and the property has a fenced in yard which would be ideal for your curious furry friend. This property is minutes from hospitals & interstate 85. Ideal for work travelers, or simply curious visitors. There's a driveway for parking.

Guest favorite
A bright living room features a comfortable gray sofa, patterned accent chairs, and a glass coffee table. Large windows allow natural light to fill the space. In the outdoor area, a playground with a slide and climbing structure is visible within a fenced yard, perfect for children.
Home in Simpsonville
4.9 out of 5 average rating, 114 reviews

Spacious 4 BR Escape w/ Fenced Yard Near Downtown

Welcome to your stylish retreat, conveniently located just 3 minutes from the shopping & dining in charming Downtown Simpsonville & convenient to everything that Greenville has to offer. With 4 bedrooms, 2 full baths & a fenced in yard, this house has everything you need for your stay. Located in a safe & quiet neighborhood just 20 minutes from downtown Greenville & 5 minutes to all of your daily needs. <B>Traveling with a large group? Ask about our other 4BR house across the street!<B>

Top guest favorite
The front of the house is showcased with a white exterior and a welcoming porch. Two rocking chairs are positioned on the porch, surrounded by planters displaying seasonal flowers. A well-maintained pathway leads to the entrance, framed by decorative brick steps and a railing.
Home in Greenville
4.97 out of 5 average rating, 247 reviews

Spectacular home 1 mile from Main St Greenville!

Enjoy your stay in this charming up to date house 1 mile from Main St Greenville! Take a walk through the Historic Pinckney district on your way to Greenville’s museums, restaurants, theaters, and stunning Reedy River Falls Park. Easy access to the Swamp Rabbit biking and walking trail, and just 4 blocks from the upcoming Unity Park. House is located on quiet residential street with private driveway. Relax on rocking chairs on front porch or around a portable fire pit in large backyard.

Guest favorite
A contemporary living area features a comfortable gray sofa with accent pillows, positioned beside a coffee table. A flat-screen TV is mounted on a shiplap wall above an electric fireplace. Natural light floods the space through window coverings, illuminating the stylish decor.
Home in Simpsonville
4.96 out of 5 average rating, 135 reviews

Modern Farmhouse in Downtown Simpsonville, SC

Newly renovated two-bedroom home located in downtown Simpsonville, within easy walking distance of an excellent variety of restaurants, shops and places of interest. A spacious private balcony, leading off from the main bedroom suite overlooks a peaceful backyard... a great place to relax outdoors! The kitchen is fully equipped for preparing great meals. Our home is thoroughly and professionally cleaned & sanitized. ***Please note there is a train that runs midday and late at night.

Top guest favorite
A bright living room features two leather sofas positioned around a cozy area rug. Large windows provide ample natural light, with a mounted TV above a wooden mantel. Decorative wall frames add character to the space, complemented by a soft throw draped over one of the sofas.
Home in Simpsonville
4.96 out of 5 average rating, 157 reviews

Simpsonville Southern Comfort

Welcome to Simpsonville Southern Comfort! Our home offers a comfortable, completely remodeled space with all of the amenities of home to make your stay enjoyable. This home is in a GREAT location just a 5-minute drive from the conveniences of the Five Forks area, and a short 7-minute drive to the enjoyment of The Square in Downtown Simpsonville. Our home is also a quick 20-minute drive from GSP International Airport, and 20 minutes from Downtown Greenville. Enjoy your stay!

Top guest favorite
A split-level home is set amidst a well-maintained lawn, featuring a welcoming entrance with a front door framed by windows. Lush greenery and trees surround the property, and a pathway leads to the entrance, providing easy access.
Home in Greenville
4.99 out of 5 average rating, 183 reviews

2 Living Spaces -2800 ft.²- Sleeps 10

This spacious split-level house is in a quiet neighborhood and has plenty of room for 10 guests. Enjoy a king bed in the master bedroom, and 3 additional bedrooms, each featuring a queen bed. 2 single trundle beds are also available for the little ones. This home has space to gather everyone together or spread out and have some quiet time. Some fun features of this home are an outdoor fire pit, pool table, fenced backyard, deck with grill, and 3 smart TVs. 4 bedroom 3 bath home.

Guest favorite
A living area features large windows that allow ample natural light, complemented by soft white drapes. A comfortable sofa and two armchairs are arranged around a light area rug, with a small table nearby. A television is mounted above a modern fireplace.
Home in Greenville
4.89 out of 5 average rating, 141 reviews

Greenville Prime Location-Steps from Swamp Rabbit

You'll love the abundant natural light in this peaceful one bedroom retreat. We are located in the Pettigru Historic District and are just a 5 minute walk from Bon Secours Wellness Arena and a 15 minute walk to Main Street. This is an upstairs unit (1 of 3 total units located within the triplex) and has a private, exterior entrance. There's a kitchen with all the utensils, pots, bowls, plates, cups, etc. that you could need for your stay as well as a stocked Nespresso machine!

Top guest favorite
A charming exterior view of the home features light beige siding and a welcoming blue front door. Windows with blinds allow natural light to brighten the interior. The manicured front yard includes low shrubs, and a concrete walkway leads to the entrance.
Home in Greenville
4.95 out of 5 average rating, 128 reviews

Greenville Modern Retreat - 8 minutes to Downtown

Decorated in a mid century modern theme, this home is perfect for couples and business travelers looking for a peaceful, modern aesthetic filled with natural light. This home is located in San Souci just 2.5 mi (8min drive) to downtown Greenville. It is also conveniently located 1/2 mi to the Swamp rabbit trail and the Swamp Rabbit Grocery. Please see “Where you’ll be” section for further description of location and the neighborhood. We're excited to have you join us!

Top guest favorite
A calming bedroom features a spacious bed with crisp white linens and decorative pillows. A ceiling fan enhances airflow, while a large TV is mounted on the wall. A potted plant adds a touch of greenery, and soft light is provided by bedside lamps.
Home in Greenville
4.99 out of 5 average rating, 147 reviews

Family & Pet Friendly Home - Sleeps 8

Our home is absolutely perfect for entertaining, work and relaxation. Enjoy fast wifi and free coffee. Connect over a meal at our spacious dining table. Families will love the large, fenced-in backyard, toys and board games in our huge rec room, complete with ping pong table! Quiet and easy connections to Greenville & Simpsonville. Only 5 mins from Discovery Island Waterpark. Community park and playground accessible with lots of space to roam with family or pets.

Popular amenities for Simpsonville house rentals

When is the best time to visit Simpsonville?

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Quick stats about house rentals in Simpsonville

  • Total vacation rentals

    Explore 80 vacation rentals in Simpsonville

  • Nightly prices starting at

    Simpsonville vacation rentals start at ﺩ.ﺇ110 per night before taxes and fees

  • Verified guest reviews

    Over 2,360 verified reviews to help you choose

  • Family-friendly vacation rentals

    40 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    40 properties have a dedicated workspace

  • Wi-Fi availability

    80 of Simpsonville vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Simpsonville rentals

  • 4.8 Average rating

    Simpsonville stays are highly rated by guests—averaging 4.8 out of 5!