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House vacation rentals in Greenville County

Find and book unique houses on Airbnb

Top-rated house rentals in Greenville County

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious living area features a comfortable sectional sofa and a recliner. Natural light enters through large windows, creating a welcoming environment. Framed artwork adorns the walls, complementing the warm tones of the room. A dining area is visible in the background.
Home in Taylors
4.98 out of 5 average rating, 250 reviews

Vintage home near downtown Greenville.

Cozy home with vintage look. Be in downtown Greenville or Paris Mt. State Park in under ten minutes. Close to shopping and the state Farmer's Market is a mile away. Acre yard gives spacious feeling. A complimentary Power Point of South Carolina and local history, culture, events, and business is available to help introduce you to one of the country's best kept secrets. Cut flowers and help yourself to our organic garden for use during your stay (seasonally). Small RV parking but no hook ups.

Top guest favorite
An open living space features a large wooden bar countertop with three metal stools. A cozy seating area is arranged around a stone fireplace, complemented by a television mounted on the wall. Light streams in from the adjacent room, highlighting the rustic charm.
Home in Greenville
4.9 out of 5 average rating, 153 reviews

Fisher's Paradise on Lake Saluda w Boat Ramp

Stay at Saluda Lake Landing in this unique lakefront property getaway that has a house, cafe, boat ramp, and dock. Perfect for fishing, kayaking, paddle boarding and more. Once home, relax and cook the days catch indoors and out. This property is partially public as we do get other customers for the cafe, dock, and boat ramp. Please be aware that our employees will be around the property during normal working hours. If you are planning to bring your furry friend with you please reach out prior.

Top guest favorite
An open-concept living area features a modern kitchen with stainless steel appliances and a spacious island, complemented by a dining table. A cozy living room is equipped with a soft sectional sofa facing a mounted television and warm electric fireplace. Natural light enhances the inviting atmosphere.
Home in Greenville
4.97 out of 5 average rating, 158 reviews

Greenville GEM Luxurious Retreat in Prime Location

Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating.  Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Top guest favorite
A serene bedroom features a four-poster bed draped with soft textiles, complemented by cozy fur accent pieces. Warm lighting creates a relaxing ambiance, while decorative wall frames and patterned rugs enhance the inviting atmosphere. Multiple windows allow natural light to filter in.
Home in Easley
4.99 out of 5 average rating, 128 reviews

Comfy, cozy duplex apt in old home downtown Easley

Comfortable, CLEAN, safe, serene, remodeled duplex apartment w/private entrance thru back of home - 20 mins to Gville/Clemson. Stocked for cooking. Near hiking, climbing, kayaking, diving, fishing, restaurants, breweries, pubs, theatres, museums, hospitals, live music venues, shopping, universities, and churches. Come home to comfy robes and rooms designed for relaxation. Note: Easley has a train track downtown - a few blocks away. This is important to note. Self check-in thru passcode

Guest favorite
A cozy living room features a warm leather chair and a round coffee table on a light rug. A spacious dining area, with a wooden table and stylish seating, is illuminated by natural light. Elegant wallpaper depicting trees adds a serene backdrop.
Home in Greenville
4.98 out of 5 average rating, 123 reviews

West Village Modern Sanctuary

Step outside your private abode and explore the Swamp Rabbit Trail, a scenic greenway perfect for biking, or a quick drive to downtown's main attractions. Immerse yourself in the artistic energy of the West End Village's galleries, or try delicious local restaurants, coffee shops, and bakeries. This charming retreat offers the perfect blend of comfort, convenience, and purposeful style, ideal for families, friends, or remote workers seeking an authentic Greenville experience.

Guest favorite
A charming exterior view of the home features light beige siding and a welcoming blue front door. Windows with blinds allow natural light to brighten the interior. The manicured front yard includes low shrubs, and a concrete walkway leads to the entrance.
Home in Greenville
4.94 out of 5 average rating, 142 reviews

Greenville Modern Retreat - 8 minutes to Downtown

Decorated in a mid century modern theme, this home is perfect for couples and business travelers looking for a peaceful, modern aesthetic filled with natural light. This home is located in San Souci just 2.5 mi (8min drive) to downtown Greenville. It is also conveniently located 1/2 mi to the Swamp rabbit trail and the Swamp Rabbit Grocery. Please see “Where you’ll be” section for further description of location and the neighborhood. We're excited to have you join us!

Top guest favorite
The treehouse structure features a distinctive A-frame design with large glass paneling allowing for abundant natural light. Surrounded by trees, an outdoor deck with seating complements the lush woodland setting. The rooftop deck above adds to the unique architectural appeal.
Home in Greenville
4.99 out of 5 average rating, 259 reviews

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Top guest favorite
A spacious living area features comfortable leather sofas and a wooden coffee table. Two landscape paintings are displayed on the wall, complementing the warm tones of the decor. Natural light enters through the window, illuminating the modern kitchen in the background.
Home in Greenville
4.98 out of 5 average rating, 151 reviews

Private Gateway to Greenville and Paris Mountain

Escape to this updated Greenville home, perfect for groups! Enjoy an open-concept living space, a 75" Smart TV with blazing-fast Wi-Fi, a fully-equipped kitchen, and a private backyard with a propane grill, fire pit, & hammocks. Every bedroom features a queen bed or larger for ultimate comfort. Ideally located just 1.5 miles from Paris Mountain State Park and a 15-min drive to vibrant Downtown Greenville. Your ideal base for adventure and relaxation.

Guest favorite
The entrance features a welcoming porch with two woven chairs placed on either side of a front door, adorned with a simple wreath. The house showcases a white facade with a gabled roof and is surrounded by a neatly maintained lawn.
Home in Travelers Rest
4.91 out of 5 average rating, 112 reviews

Cozy home in downtown TR

Enjoy your stay at this cozy two bedroom home just off the Swamp Rabbit Trail within walking distance of the beautiful small town of Travelers Rest. You will be near excellent food choices, wine and craft beer or hiking and biking adventures. This newly renovated home has a great living space with two beautiful bedrooms and bathrooms. Each bedroom has a king bed. You will have access to the entire home. Minimum 2 night stays.

Top guest favorite
A welcoming cabin is nestled among tall trees, softly illuminated by string lights against the evening sky. A pathway leads toward the water, inviting relaxation with the gentle ambiance of nature surrounding the space.
Home in Easley
4.92 out of 5 average rating, 204 reviews

Spectacular Lakefront Retreat on the Saluda

Stunning views, quiet, still waters, wildlife in its natural habitat. This and more is what you'll find at Lakepoint on the Saluda. Better yet, this property is located on the water with 460' of lakefront and is just minutes from downtown Greenville, Furman, and Paris Mountain. Within 35 minutes you can be in Clemson. Includes kayaks, a canoe, hot tub (SEASONAL), work out room, and some of the best fishing in the upstate!

Top guest favorite
A bright living area showcases an inviting layout with two sets of double doors leading to a patio. A comfortable gray sofa is positioned near a wooden coffee table, complemented by a fireplace and a dining table set for six. Natural light enhances the overall space.
Home in Greenville
4.97 out of 5 average rating, 150 reviews

GVL Historic Lux -Walk Dntwn/Swamp Rabbit/BonSecrs

Welcome to your bright and inviting stay in Greenville’s charming Pettigru Historic District. You’ll be in one of Greenville’s most walkable neighborhoods — just minutes walk from the Swamp Rabbit Trail, Downtown, Bon Secours Wellness Arena, and the city’s best restaurants, shops, and parks. High ceilings and large windows fill the space with natural light, creating a calm, welcoming atmosphere.

Guest favorite
A bright living room features large windows allowing natural light to fill the space. Two cozy armchairs and a sofa surround a coffee table, complemented by a modern TV stand. A patterned area rug adds warmth to the clean, neutral decor.
Home in Taylors
4.96 out of 5 average rating, 121 reviews

Sleek 3BR Pet-Friendly Oasis, Close to City

Step into Taylor's Grove West in Greenville's Eastside. A modern oasis, this 3-bedroom home sparkles with vibrant emerald green and cool blue tones. Showcasing a unique and light-filled aesthetic, its location is prime, with key Greenville attractions just a 20-minute drive away including Downtown Greenville, Greer, and TR. Experience refined Upstate living in style.

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