
Guesthouse vacation rentals in Greenville County
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Top-rated guesthouse rentals in Greenville County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Greenville County guesthouse rentals
Family-friendly guest house rentals

Clean. Comfortable. Convenient.

Private Suite in Downtown Simpsonville

Fairy Forest Cabin with Hot Tub at Table Rock

Quaint guest cottage in Upstate

1950's Cottage- Close to Downtown & Furman

The Backyard Bungalow On the Trail

Forested Retreat-Scenic Above Garage Suite

Pickens Paradise
Guest house rentals with a patio

Guest Cottage with Private Drive

Country-Clubhouse Tiny Home. Close to downtown!

Serene 2BR Retreat on 11 Acres-Family/Pet Friendly

Fun, cozy cottage for two w/games, deck in Easley

Sugar Creek Retreat

1 bedroom guest house on horse property in Tryon

2BR Guesthouse Retreat Near Furman w/ Pond Views

Historic Earle Street Guest House
Guest house rentals with a washer and dryer

The Spring Valley Retreat

Quiet King Two Bedrm House

Chic Studio with Private Deck

The oaks cottage

Just off Main near Taylors Mill - Clean & Comfy

Adorable renovated private house w/ parking.

Charming 1BD/1BA Studio, 4 Miles to Downtown GVL

Beautiful guest house
Destinations to explore
- Smoking-friendly rentals Greenville County
- Rentals with outdoor seating Greenville County
- Farmstay rentals Greenville County
- Tiny house rentals Greenville County
- Condo rentals Greenville County
- House rentals Greenville County
- Rentals with an accessible height toilet Greenville County
- Rentals with a washer and dryer Greenville County
- Fitness-friendly rentals Greenville County
- Rentals with breakfast Greenville County
- Rentals with a hot tub Greenville County
- Rentals with a patio Greenville County
- Cabin rentals Greenville County
- Rentals with pools Greenville County
- Rentals with a fire pit Greenville County
- Family-friendly rentals Greenville County
- Waterfront rentals Greenville County
- Rentals with lake access Greenville County
- Rentals with a kayak Greenville County
- Private suite rentals Greenville County
- Loft rentals Greenville County
- Rentals with a fireplace Greenville County
- Pet-friendly rentals Greenville County
- Rentals with an EV charger Greenville County
- Apartment rentals Greenville County
- Townhouse rentals Greenville County
- Guesthouse rentals South Carolina
- Guesthouse rentals United States
- Blue Ridge Parkway
- River Arts District
- Gorges State Park
- Table Rock State Park
- Chimney Rock State Park
- Mountaintop Golf & Lake Club
- The North Carolina Arboretum
- Tryon International Equestrian Center
- Lake Lure Beach and Water Park
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Jump Off Rock
- Biltmore Forest County Club
- Vineyards for Biltmore Winery
- Old Edwards Club
- Victoria Valley Vineyards
- French Broad River Park
- Thomas Wolfe Memorial
- Woolworth Walk
- Discovery Island
- Haas Family Golf
- Carl Sandburg Home National Historic Site
- Wellborn Winery
- City Scape Winery