
Vacation rentals in Santa Cruz
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Top-rated vacation rentals in Santa Cruz
Guests agree: these stays are highly rated for location, cleanliness, and more.

Casa de Veraneo
Lleva a toda la familia a este fantástico lugar con muchas zonas para divertirse. Cerca a todas las amenidades de Coronado, a pocos minutos de playas, laguna de San Carlos y a tan solo una hora y media de la ciudad. El PH cuenta con piscina del PH y una privada, en una zona tranquila y espaciosa. Encontraras 4 supermercados, farmacias, hospital privado (urgencias). Cerca a actividades campestres, playas, montañas, lago. Tiene en un gazebo con todas las comodidades. El lugar es seguro y completo.
ValueLocationIndoor spaces
4.94 out of 5 average rating, 67 reviews
Beach House-Amazing Pool & Jacuzzi - Pet Friendly
Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.
FamilyLocationDecor
4.98 out of 5 average rating, 222 reviews
Paradishaus in Natur in Playa Coronado mit Pool
Genieße entspannte Tage mit der ganzen Familie oder Deiner Freunden in dieser friedlichen Unterkunft mit viel Natur! Der Strand ist in 5 Minuten zu Fuß entfernt. Viele verschiedene Geschäfte sind mit einem Auto in 8 Minuten zu erreichen. Zwei kleine Läden sind auch in 5 Minuten zu Fuß erreichbar. Für alles ist im Haus gesorgt: Klimaanlagen in jedem Zimmer, großer 75" TV, Waschmaschine, Trockner, Föhn, Handtücher.... alles was Du brauchst. Der Pool sorgt für Erfrischung – ein Ort zum Wohlfühlen!
FamilyLocationHospitality
4.94 out of 5 average rating, 35 reviews
The Dream of Playa Coronado
Whether traveling to Playa Coronado to relax, spend time with family, flee the cold weather or scout your retirement destination, this house is perfectly located in the heart of Playa Coronado and features an airy, tropical ambience, a pool with loungers to soak up the sun, two bohios with dining/lounging areas, hammocks to sway your day away and a BBQ to cook fresh fish bought at the local fish market. The house has a water well so no problems with access to water during the Dry Season.
LocationValueBeach
5.0 out of 5 average rating, 43 reviews
Casa de Campo con Piscina / Villas del Maria
Relájate en este espacio tranquilo y elegante. Este alojamiento es perfecto para grupos de personas, viajes en familia o una puerta de entrada romántica. Ubicado en Sora, a 5 minutos de la Interamericana, a 15 minutos de supermercados y lugares para comer en Coronado. Villas del María es un lugar seguro y relajante para pasar el tiempo en familia. Disfruta de un acogedor lugar silencioso con todo lo necesario para la estancia. A ti y a tu familia les encantará este lugar!
FamilyLocationAir conditioning
4.86 out of 5 average rating, 22 reviews
Playa Malibu Beach House.
Wake up to the sound of the waves at this beautiful oceanfront home in Playa Malibu, where the beach is literally your backyard. Step outside and enjoy direct beach access, morning walks on the sand, and unforgettable sunsets over the water. The home features a private pool, BBQ area, and an outdoor dining space perfect for shared meals and long, laid-back evenings. Inside, the house offers a cozy, comfortable, and relaxed vibe, with all the essentials for a stress-free stay.
FamilyLocationComfort
4.95 out of 5 average rating, 44 reviews
Modern House with Great Views and Heated Pool
Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.
ValueLocationCheckout
4.82 out of 5 average rating, 337 reviews
Villa Acuario
Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.
LocationValueGrill
4.76 out of 5 average rating, 170 reviews
Luxury Beachfront Home • Private Pool • Coronado
Welcome to your private beachfront retreat in Coronado, one of Panama's premier Pacific Coast communities. This beautiful home combines contemporary design with relaxed coastal living. Enjoy a private pool, tropical gardens, spacious indoor and outdoor areas, a fully equipped kitchen, Wi-Fi, ocean views and direct access to a wide, beautiful beach. Perfect for families and groups seeking privacy, comfort and a true beachfront experience.
FamilyLocationBeach
4.89 out of 5 average rating, 18 reviews
Spectacular Beachfront House
Beautiful house with private beach access right on the property. Relax on the hammocks and be surrounded by nature, with the best ocean view. Only 10 minutes drive from Coronado with all its amenities. There are two wonderful caretakers on the property who are in charge of security, cleaning, and can answer questions and help you with anything you need.
LocationFamilyGrill
5.0 out of 5 average rating, 41 reviews
Casa de Campo- familiar Bejuco-Chame
Este lugar único tiene su propio estilo. Apropiado para celebrar cumpleaños, proyectos, trabajar, escribir y estar totalmente en tranquilidad .Leer un buen libro, darse una buena terapia de piscina y compartir grandes momentos y eventos en familia o pareja .Además de poder estar en un área de vivencias cultural.
FamilyValueQuiet
4.88 out of 5 average rating, 50 reviews
Paseo por Las Nubes
Relájate en esta escapada unica y tranquila a solo una hora y media de la ciudad. Cada rincón de este lugar mágico fue meticulosamente diseñado para brindar el escape perfecto a las parejas que buscan intimidad, serenidad y momentos inolvidables juntos.
FamilyLocationNearby
4.84 out of 5 average rating, 159 reviewsPopular amenities for Santa Cruz vacation rentals
Other great vacation rentals in Santa Cruz

Disfruta la vista al cerro Picacho
FamilyValueAir conditioning
4.9 out of 5 average rating, 86 reviews
20th Flr Beachfront Nueva Gorgona, Panamá 2/3 unit
FamilyLocationHeating
4.89 out of 5 average rating, 71 reviews
Hermosa villa de playa
FamilyValuePool
4.82 out of 5 average rating, 72 reviews
Blue Sky Lodge; la mejor vista en Altos del María
ValueLocationParking
4.94 out of 5 average rating, 68 reviews
Exclusiva Villa con Piscina, y Playa a Minutos
FamilyLocationComfort
4.94 out of 5 average rating, 78 reviews
Family Paradise | Pool, Jacuzzi & Garden
LocationFamilyCheckout
4.83 out of 5 average rating, 24 reviews
Gorgeous Beachfront High Floor
LocationValueQuiet
4.97 out of 5 average rating, 39 reviews
Tu escape perfecto en la montaña
LocationValueKitchen
5.0 out of 5 average rating, 15 reviewsDestinations to explore
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