Vacation rentals in Santa Cruz

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Top-rated vacation rentals in Santa Cruz

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Guest favorite

An expansive view of a tranquil beach is seen, with soft sandy shores meeting clear turquoise waters. The horizon features a blend of blue sky and distant buildings, while palm trees and shaded cabanas dot the beach area.

Condo in Chame District

4.96 out of 5 average rating, 163 reviews

Exclusive Beachfront apartment 1Hour from Pma City

ESPECTACULAR apartamento de lujo FULL EQUIPADO con 3 recamaras (todas con vista directa al mar), 2 baños completos y medio baño de visita; cuarto y baño de servicio. Finos acabados, cocina 100% de acero inoxidable y aires acondicionados en todo el apartamento de alta eficiencia. Condominio con concepto "Hotel Style Living"; Restaurante y Bar para las noches (de Jueves a Domingo), snack bar en el area de la piscina y un Tiki Bar en la playa, ademas de cancha de Volleyball , Tenis, basketball.

Top guest favorite

An aerial view showcases a serene saltwater pool framed by lush greenery. Red umbrellas provide shade for outdoor seating areas. The open kitchen and dining space are visible, along with comfortable hammocks situated nearby, offering a relaxed atmosphere for guests.

Home in Costa Esmeralda

4.98 out of 5 average rating, 171 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with solar and battery backup systems.

Top guest favorite

The exterior of the three-story beach house is showcased, featuring terracotta roofs and lush landscaping. Palm trees and colorful flowers enhance the vibrant surroundings, while the ocean is visible in the background, complementing the peaceful neighborhood setting.

Home in San Carlos

4.95 out of 5 average rating, 123 reviews

OceanView-Rooftop Jacuzzi&Pool | Concierge Service

Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 8.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base rate covers up to 4 guests, with a $40 charge per additional person, per night.

Top guest favorite

A stone paved area features four wooden chairs arranged around a central fire pit, illuminated by soft landscape lighting. In the background, a cabin structure can be seen, bordered by lush greenery and softly lit paths, creating an inviting outdoor space.

Cabin in Provincia de Panamá Oeste

4.87 out of 5 average rating, 238 reviews

Buenavista Cabin by Casa Amaya

Casa Amaya is a cabin complex located one hour from the capital city, in Chicá de Chame, with pleasant temperatures between 18 and 24 degrees, where you can get in touch with nature and relax with your partner, friends or family. Other cabins: https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/panoramabycasaamaya https://www.airbnb.com/h/horizontebycasaamaya We have an electric generator in case of outages.

Guest favorite

The image captures a serene sunset over the ocean, with vibrant hues of orange and purple reflecting on the water. The shoreline is lined with trees, while distant high-rise buildings are visible against the sky, creating a peaceful coastal scene.

Apartment in Nueva Gorgona

4.86 out of 5 average rating, 177 reviews

Nueva Gorgona Beach Front Condo for 4 people

Condo Gorgona Beach Front is located on the 6th floor of Royal Palm, facing the beach with ocean views from the balcony and the room. It has 3 swimming pools, direct access to the beach, restaurant, address and more. This cozy apartment for a family or friends of 4 is an excellent economic option to enjoy luxurious amenities within the building. We treat each property like a hotel, so we invite you to enjoy this cozy apartment as you deserve. Book now!

Top guest favorite

A bright dining area features a round wooden table surrounded by six turquoise chairs. Large windows allow natural light to fill the space, showcasing a cozy atmosphere. A wooden dresser and potted plants add touches of comfort. Arched openings lead to other rooms.

Home in El Valle de Antón

4.95 out of 5 average rating, 163 reviews

Rustic family mountain home - 5 min walk to town!

Rustic family home with exquisitely landscaped garden complete with bridge over natural stream. Outdoor chill out space with barbecue and terrace under roof with hammocks on one side of the house, and a pergola with lounge area and gas grill on opposite side of the house. Centrally located to main attractions, only a 7 minute walk to the main market. Peaceful, relaxing refuge surrounded by views of nature and the cloud forest.

Top guest favorite

An inviting infinity pool is positioned on a spacious patio, overlooking a sweeping mountain view. Two lounge chairs are arranged on the deck, facing the water, while lush greenery and colorful blooms enhance the serene environment surrounding the pool area.

Cottage in Altos del Maria

4.94 out of 5 average rating, 159 reviews

Mountain Cottage with Great View

Mountain Cottage, with spectacular views of the Altos del María Mountains, perfect for relaxing or spending time with the family. It features a infinity pool, spacious outdoor spaces, Smart TV and A/C in all rooms and living room, Wi-Fi throughout the property, and is fully equipped. Includes Prime Video service. It also has a fire pit and a gas BBQ. Complimentary late checkout is available for rentals departing on Sundays.

Top guest favorite

An infinity pool blends seamlessly into the ocean view, with a person standing at the edge. A lounge chair is positioned nearby, providing a relaxing spot to enjoy the scenery under a clear blue sky.

Condo in San Carlos

4.96 out of 5 average rating, 126 reviews

New ocean apartment in beautiful beach complex

Modern new condo with breath taking views of the Pacific Ocean. We are in a beautiful new beach complex, Punta Caelo, with direct beach access, a beach club, and several large swimming pools. The Social Area is resort quality with deck chairs, infinity pools, billiards, children’s pools and pool beds. The apartment is open and spacious with a fully stocked kitchen and large terrace directly looking out over the ocean.

Guest favorite

A modern living area features a gray sofa paired with two yellow chairs, accented by decorative cushions. A wooden coffee table is centered in front of a sleek television set mounted on the wall. Light streams in through a nearby window, enhancing the open layout.

Home in Bejuco

4.9 out of 5 average rating, 10 reviews

Country House with Pool / Villas del Maria

Relax in this quiet and elegant space. This place is perfect for groups of people, family trips, or a romantic gateway. Located in Sora, 5 minutes from Interamericana, 15 minutes from supermarkets and places to eat in Coronado. Villas del María is a safe and relaxing place to spend time as a family. Enjoy a cozy quiet place with everything you need for your stay. You and your family will love this place!

Guest favorite

A large swimming pool features clear blue water surrounded by lush palm trees. Comfortable lounge chairs are positioned nearby, offering a place to relax. The building in the background has multiple glass windows, providing a modern aesthetic to the tropical setting.

Apartment in San José

4.86 out of 5 average rating, 134 reviews

B11-Tropical beach paradise, 2R/2B condo, w/pool

Disconnect for a few days from the routine. Have fun with your partner or family in our apartment in Punta Barco Viejo, we have everything you need to be comfortable and have fun in one of the most exclusive areas of the area. We have everything nearby for your best convenience, restaurants, banks, supermarkets ... I´ll deliver a personalized 5 stars attention. Oh and of course, the BEACH 5min by car!

Top guest favorite

A spacious exterior view of the loft @ Londolozi showcases a two-story structure with a red-tiled roof. Large glass doors open to a patio area with lounge chairs and a hammock, surrounded by lush greenery and mountains in the background.

Cottage in Sorá

4.95 out of 5 average rating, 112 reviews

Luxury Private Cottage in Altos del Maria

This property is situated within the gated community of Altos del Maria. Surrounded by lush forest and rivers, the loft @ Londolozi is for guests who appreciate a sense of luxury while being close to nature. While Altos del Maria enjoys a warm tropical climate, there is a cooling breeze in the mountains that is not often present in the coastal areas.

Guest favorite

The two-story house is illuminated at night, showcasing vibrant exterior colors and a balcony on the upper floor. Large windows are visible, allowing light to spill out. A seating area is set up in the outdoor space, surrounded by plants and decorative string lights.

Home in El Valle de Antón

4.8 out of 5 average rating, 242 reviews

Casa Antares by Esther

Agradable casa de dos pisos con vistas a las montañas. **NO APTO PARA PERSONAS CON POCA MOVILIDAD, FAVOR LEER SECCIÓN DE SEGURIDAD** Dos cuartos privados en la parte superior con balcón en la habitación principal. Baño, sala y cocina en la planta baja. Contamos con bicicletas para que puedan pasear alrededor del Valle de Antón.