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Vacation rentals in Santa Cruz

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Top-rated vacation rentals in Santa Cruz

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Guest favorite
A panoramic view captures the merging of the ocean and river, framed by lush greenery. Soft pink and orange hues from the sunset reflect on the water, enhancing the serene atmosphere. The expansive sky is dotted with gentle clouds, completing the tranquil scene.
Apartment in San Carlos
4.88 out of 5 average rating, 247 reviews

At Playa Corona, relaxing is easy.

Corona del Mar is an exclusive building of 26 apartments located in Playa Corona, in front of the Corona River and the beach, where you will find peace and privacy. Direct access from the building. Its privileged location allows you to be close to everything. You can choose between the shopping centers and supermarkets of Coronado or Playa Blanca. Overlooking the mountains and the sea. Resting has never been easier. El Valle, El Caño, Surfing, Rest, Beach, River, Life, Restaurants, Green, Vacation

Top guest favorite
An aerial view of the property showcases a spacious layout surrounded by lush greenery. A large saltwater pool and a hot tub are visible alongside a well-maintained outdoor area with red umbrellas providing shade. The roof of the main structure features a brown tone, blending with the natural surroundings.
Home in Costa Esmeralda
4.98 out of 5 average rating, 185 reviews

Beach House-Amazing Pool & Jacuzzi & Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Guest favorite
A well-appointed bedroom features a king-size bed with a light-colored coverlet. Two bedside lamps provide soft illumination next to the headboard. A comfortable chair sits beside a large window, showcasing views of greenery outside, while a patterned rug adds texture to the space.
Apartment in Coronado
4.91 out of 5 average rating, 32 reviews

Stunning 1BR Apt with Golf Course Views

Escape to unparalleled luxury at apartment in Coronado Beach, nestled on one of Panama's most spectacular golf courses designed by the legendaries Tom and George Fazio. Just 1 hour and 15 minutes from Panama City, this exclusive getaway offers the perfect blend of elegance and convenience. Our property features an inviting social area with two pools, a sauna, and game room. Only five minutes from the beach, this is the ideal retreat for those seeking both relaxation and adventure.

Guest favorite
An aerial view reveals a stretch of coastline featuring sandy beaches with a mix of dark volcanic sand and vibrant turquoise water. Lush greenery lines the shore, complemented by residential areas visible in the background, creating a serene and inviting landscape.
Tiny home in San Carlos
4.8 out of 5 average rating, 125 reviews

Cozy beach cabin at Costa Esmeralda.

Cozy private community cabin on a triple space for up to three people located in Costa Esmeralda beach, over the Pacific ocean. Very quiet area with a 2,200 Square meter patio with trees and vegetation. Relax enjoying of the tropical sun, warm temperatures all year long and the ocean breeze. Only 8 minutes away by walk from the closest beach with warm waters and volcanic black sand. 10 minute drive to Coronado (Grocery Stores, restaurants, bakeries, movie theater, malls and more).

Top guest favorite
A modern single-story house is displayed with a large front porch and a carport. The exterior features a mix of light and dark materials, with a neatly landscaped yard and a white picket fence. Clear blue skies and scattered clouds complete the setting.
Home in Chame District
5 out of 5 average rating, 29 reviews

Summer House

Take the whole family to this fantastic place with many areas to have fun. Close to all the amenities of Coronado, a few minutes from beaches, San Carlos lagoon and just an hour and a half from the city. The PH has a PH pool and a private one, in a quiet and spacious area. You will find 4 supermarkets, pharmacies, and a private hospital (emergency room). Close to country activities, beaches, mountains, lake. It has a gazebo with all the amenities. The place is safe and complete.

Top guest favorite
A stone paved area features four wooden chairs arranged around a central fire pit, illuminated by soft landscape lighting. In the background, a cabin structure can be seen, bordered by lush greenery and softly lit paths, creating an inviting outdoor space.
Cabin in Provincia de Panamá Oeste
4.88 out of 5 average rating, 263 reviews

Buenavista Cabin by Casa Amaya

Casa Amaya is a cabin complex located one hour from the capital city, in Chicá de Chame, with pleasant temperatures between 18 and 24 degrees, where you can get in touch with nature and relax with your partner, friends or family. Other cabins: https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/panoramabycasaamaya https://www.airbnb.com/h/horizontebycasaamaya We have an electric generator in case of outages.

Guest favorite
The modern house is set amidst lush greenery, featuring a sleek design with large glass windows. An infinity pool is positioned on a spacious patio that offers unobstructed views of the surrounding hills, creating an inviting outdoor space for relaxation.
Home in Altos del Maria
4.81 out of 5 average rating, 301 reviews

Modern House with Great Views and Heated Pool

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

Guest favorite
A balcony with a panoramic view of the coastline and turquoise waters is furnished with two cozy chairs and a small table. A long wooden bar table stands nearby, offering additional seating. The bright blue sky complements the scenic landscape.
Apartment in Nueva Gorgona
4.88 out of 5 average rating, 60 reviews

Apt 15th floor beachfront/ 4 pools/Air conditioning/WIFI/PKG

Relax with the whole family at this peaceful place to stay. The building has 4 swimming pools, 1 Jacuzzi, 1 sauna, gym, volleyball court, futsal, pickleball or mini tennis, gazebos, a restaurant and BBQ area. The latter is rented for an additional $25. The apartment has 2 bedrooms, a living room, a breakfast area, a full white line with a dishwasher, a laundry center, 3 air conditioners, a hair dryer, an iron, and a balcony. 1 queen bed and a bunk bed.

Guest favorite
An outdoor patio space is presented with wooden chairs and a small table. Lush green grass extends towards the sandy beach, adorned with palm trees and sun loungers under thatched umbrellas, creating a calm coastal view.
Home in Chame
4.8 out of 5 average rating, 82 reviews

P/Caracol Ocean Haven View (C5-PBB) 2 bed, 2 bath

This unique place has a style all its own, steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space and an outside pergola area. (4 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views and great on-site amenities. 1km of beach to offer you the best beach and surfing experience around.

Top guest favorite
A covered patio area displays a mix of seating options, including two wicker chairs and a small glass-top table surrounded by greenery. A hammock hangs gracefully in the foreground, adding a touch of comfort to this relaxed outdoor setting.
Cottage in El Valle de Antón
4.99 out of 5 average rating, 145 reviews

Casa Campestre Los Macos, El Valle de Anton

🏡 Welcome to Casa Campestre Los Macos, a cozy retreat located in the green heart of El Valle de Antón, within an extinct volcanic crater, the largest inhabited in the world. It is an experience of total rest, in a safe and quiet area, ideal for lovers of nature, silence and fresh air. Wake up to the sound of birds singing, enjoy a cup of coffee in the garden, and spend family evenings in a fully equipped house.

Guest favorite
A wooden deck extends from the entrance, featuring two chairs positioned to enjoy the outdoor environment. The entrance leads into a well-lit interior space, framed by lush greenery that enhances the tranquil setting.
Cabin in El Valle de Antón
4.86 out of 5 average rating, 105 reviews

5 minutes from Valle I Incredible View Cabin 1

This beautiful cabin is 5 minutes before you get to Valle de Anton, it has a single space where the beds, kitchen and breakfast bar are located. Outside there is a small terrace. It has a TV with HBOMax, a coffee maker and an electric stove without an oven. The last 3 minutes of the road is a stone street, but a Picanto passes without problems. Up to 2 small dogs are allowed. Check in 3 pm and Check out 12 pm.

Guest favorite
A large swimming pool is surrounded by tropical palm trees, appearing inviting under a clear blue sky. Lounge chairs are positioned around the pool area, providing ample space for relaxation. A portion of the pool is shallow, leading toward a landscaped section with greenery.
Apartment in San José
4.85 out of 5 average rating, 144 reviews

B31-Tropical beach paradise, 2R/2B condo, w/pool

Disconnect for a few days from the routine. Have fun with your partner or family in our apartment in Punta Barco Viejo, we have everything you need to be comfortable and have fun in one of the most exclusive areas of the area. We have everything nearby for your best convenience, restaurants, banks, supermarkets ... I´ll deliver a personalized 5 stars attention. Oh and of course, the BEACH 5min by car!

Popular amenities for Santa Cruz vacation rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz