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Vacation rentals in Santa Cruz Island

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz Island

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
The sitting area features a modern gray sofa adorned with decorative pillows and is complemented by a wooden coffee table. Artwork hangs on the walls, and large glass doors provide ample natural light and views of a private balcony and the surrounding greenery.
Apartment in Puerto Ayora
4.92 out of 5 average rating, 218 reviews

Planet House Apt2 Sunny 1 BR flat. Great location

This is a beautiful legally registered property, with great views and wonderful fresh ocean breeze. Our apartment is located two blocks away from Charles Darwin Avenue. Guests can enjoy a leisurely walk to main attractions like the Charles Darwin Research Station and beach, great restaurants, cafés, shops, dive shops, tour operators and more. Great option for guests seeking flexibility, comfort and good value. The bedroom has AC, however the living area only benefits from a nice sea breeze.

Top guest favorite
Cabin in Santa Cruz Island
4.95 out of 5 average rating, 213 reviews

Casa Vikingo • Secluded Galápagos Highland Cabin

Set in a cool, fresh climate in the Santa Cruz highlands, Casa Vikingo is a contemporary lava-rock and timber cabin designed for those seeking nature, architecture, and complete privacy On a private one-hectare property of endemic forest and fruit orchard, the cabin is just 20 minutes from Puerto Ayora, with taxi transport easily arranged upon request. Wake up to views of the Pacific, soak in the private plunge tub, and experience a side of the Galápagos that few visitors ever experience.

Guest favorite
Home in Puerto Ayora
5.0 out of 5 average rating, 56 reviews

Villa Náutica | Private Jacuzzi | Design

Perfect for couples, families or friends looking to relax in style in the Galápagos Villa Náutica is an elegant loft villa with a private Jacuzzi, spacious areas and a unique nautical design inspired by my Swiss and Galapagos roots. Located in a quiet residential neighborhood, it allows you to enjoy tranquility just a 12-minute walk from downtown Puerto Ayora. It combines comfort, authenticity, and the ideal atmosphere for discovering the islands and returning to rest in a cozy retreat.

Guest favorite
A welcoming living area features sleek furniture and a natural wood floor that reflects light. Two modern chairs are positioned around a minimalistic coffee table on a round woven rug. Large double doors open to a balcony, offering scenic views of the surroundings.
Apartment in Puerto Ayora
4.84 out of 5 average rating, 183 reviews

Oceanview Suite: Casa Nido

Welcome to our one-of-a-kind, bird’s nest-inspired suite in Puerto Ayora, Galapagos. Enjoy: ๏ Ocean views from your private balcony ๏ Cozy hanging bed for ultimate relaxation ๏ Artistic tree staircase ๏ Fully-equipped kitchen ๏ High-speed Wi-Fi (120 Mbps) and workspace ๏ Ventilated living space The bathroom is located just below the suite, offering added privacy. Stroll to nearby cafes, bakeries, and restaurants. Let us help you discover the best of the islands!

Guest favorite
A modern living space is presented with a comfortable sectional sofa and a coffee table at its center. The kitchen features sleek cabinetry, a refrigerator, and contemporary appliances. Natural light fills the area through a nearby window, enhancing the open floor plan.
Apartment in Puerto Ayora
4.97 out of 5 average rating, 62 reviews

Comfortable apartment in the heart of Puerto Ayora

Wake up to the essence of the islands: savor local organic coffee in your fully equipped kitchen. Our home blends the soul of Galápagos with modern comfort, using solar panels for the water systems and high-speed Starlink internet. Enjoy a plastic-free stay with purified water on tap, plus snorkeling gear and beach towels for your adventures. Relax at the BBQ area or use the on-site laundry (detergent included). Where sustainable living meets the gentle rhythm of island life

Top guest favorite
The bright bedroom features two spacious beds with patterned bedding. Wooden beams add character to the ceiling while light fixtures create a warm ambiance. A large window allows natural light to fill the room, and a piece of art depicting a tree adorns one wall.
Bungalow in Puerto Ayora
4.9 out of 5 average rating, 315 reviews

Bright Garden Bungalow in a quiet neighborhood.

Sunshine filled, bright garden suite, next to the entrance to the Galapagos National Park and the Charles Darwin Station, and a few blocks away from some of the best restaurants, art galleries and bars in town. Located on the far end of one of Puerto Ayora's main streets, accessible to the road but removed enough to be isolated from the urban noise. An AC cools the suite when needed in the warmer months, and it’s screened windows are the alternative as well .

Guest favorite
Apartment in Puerto Ayora
5.0 out of 5 average rating, 7 reviews

Modern Suite with Pool | Puerto Ayora

Enjoy a unique stay in our modern suites in Puerto Ayora, designed for both comfort and tranquility. Relax in our pool after a day of exploring the islands or enjoy the beautiful panoramic view of the harbor from our terrace. ✔️ Ideal for couples or travelers seeking comfort and a good location ✔️ Clean, new, and well-equipped spaces ✔️ Quiet and safe environment We look forward to welcoming you so you can enjoy the Galápagos experience in complete comfort.

Top guest favorite
A spacious terrace features large windows providing abundant natural light and views of the surroundings. A colorful hammock is suspended between wooden posts, inviting relaxation. The tiled floor complements the wooden walls, creating a comfortable space suited for leisure and enjoyment.
Apartment in Puerto Ayora
4.97 out of 5 average rating, 104 reviews

Dominga Terrace/Pichincha Bank in front/Baltra av.

Located on the terrace of one of the tallest buildings on the island, you'll find a wonderful view all day long. Very easy to find, on Baltra's main avenue. Surrounded by restaurants, shops and a Banco Pichincha ATM across the street. 4 blocks from Terminal Terrestre and 3 blocks from Mercado Municipal and bus stop to rural areas. Privacy on your own open terrace equipped with exercise equipment, dining room and kitchen with utensils. Perfect for meetings.

Guest favorite
A dining table is set with elegant glassware and a bouquet of red roses. In the background, a television displays a serene landscape. The room features a warm ambiance, complemented by wooden accents and stylish decor.
Home in Puerto Ayora
4.91 out of 5 average rating, 101 reviews

Family Suite with Jacuzzi (included) photos 2026

Because we're one of the best Airbnbs.⚜️ Enjoy our Suite with your family or friends with tranquility, security, and modern and cozy comfort with everything included and quality service Enjoy our new Jacuzzi service ideal for all ages, parties, birthdays, etc. Enjoy a park in front of your stay (soccer, basketball, and children's games) Just a 3-4 minute drive to famous beaches, Las Grietas, La playa la Estación, Tortuga Bay.

Top guest favorite
Apartment in Puerto Ayora
5.0 out of 5 average rating, 62 reviews

Bright Loft/Suite by Encantadas

Modern and bright loft, fully equipped with everything you may need. It's air conditioned, has free wifi, a hot shower, hotel amenities, and more, all just a few minutes from the main pier. Your studio has a small terrace, and on the second floor, there's a perfect desk for remote working. With over 11 years in the Airbnb industry, we understand our guests' needs. Explore the Galapagos and relax in your own private studio.

Top guest favorite
A spacious dining and living area features wooden floors and a combination of natural light and soft lighting. A round wooden table is surrounded by six chairs, while a cozy seating arrangement includes a plush couch. Decorative elements include a potted plant and unique glass brick wall.
Home in Puerto Ayora
4.91 out of 5 average rating, 101 reviews

Gps Villa

Perfect Villa for family or group of friends. Located in the best neighborhood on the island, very close to the main pier, restaurants, supermarkets, souvenirs. You can enjoy our villa and its facilities. We have a heated Jacuzzi with hydrojets, patio, solarium, living room, dining room, and kitchen.

Superhost
An inviting interior space is showcased, featuring light wood accents and large glass doors. A hammock is suspended between two rooms, creating a relaxed ambiance. Natural light filters through sheer curtains, illuminating the open layout with soft shadows on polished tile floors.
Apartment in Puerto Ayora
4.89 out of 5 average rating, 161 reviews

Casa Tuna

Enjoy your vacation in Galapagos in a beautiful apartment located in a residential sector of Puerto Ayora, with a unique style that combines wood with white, comfortable rooms with TV, air conditioning and private bathroom. In addition, with a large terrace that will make your stay unforgettable.

Popular amenities for Santa Cruz Island vacation rentals

Frequently Asked Questions

  • Where is Santa Cruz Island located?

    Santa Cruz Island sits in the heart of the Galápagos Province, Ecuador, surrounded by the Pacific Ocean. It is part of the Galápagos Archipelago, known for distinct wildlife and protected natural habitats.

  • When is the best time to visit Santa Cruz Island?

    The climate on Santa Cruz Island is often comfortable year-round, with dry and warm conditions frequently suggested for outdoor activities. Many travelers appreciate the wildlife viewing opportunities available during alternating wet and dry seasons.

  • What are some things to do near Santa Cruz Island?

    Explore locally guided wildlife excursions, visit the Charles Darwin Research Station, and wander through traditional markets in nearby Puerto Ayora. Activities such as snorkeling, hiking, and bird spotting are frequently suggested for travelers.

  • How is the weather near Santa Cruz Island?

    Santa Cruz Island typically has mild tropical conditions, with warm temperatures and occasional rainfall distributed throughout the year. Visitors often experience comfortable days and cooler evenings, so packing for variable weather is suggested.