
House vacation rentals in Santa Cruz Island
Find and book unique houses on Airbnb
Top-rated house rentals in Santa Cruz Island
Guests agree: these houses are highly rated for location, cleanliness, and more.

Shangri-La Legal Rental steps to the beach
Shangri-La is described as an imaginary remote paradise, secluded hideaway, a haven of beauty, tranquility, or as paradise on earth. Now you don't have to imagine Shangri-La, you can see it for yourself! Located in a secluded "auto-free" zone a short aqua taxi ride from Puerto Ayora. Footsteps away is Playa de Los Alemanes. Santa Cruz Island location makes for a perfect vacation making it easy to do day trips to nearby islands. Shangri-La is the perfect place for you to enjoy Galapagos.
ValueLocationCheck-in

Great location, modern 4 guest house
Beautiful and legally registered property with great location, thoroughly decorated, comfortable for families or friends. Located 2 blocks away from Charles Darwin Ave. Guests can enjoy a leisurely walk to main attractions like the Charles Darwin Research Station and beach, restaurants, cafés, shops, tour operators and more. Great option for guests seeking flexibility and comfort. All bedrooms have AC. Other areas benefit from cross ventilation and high ceilings keeping the house cool.
LocationFamilyKitchen

Villa Náutica | Private Jacuzzi | Design
Perfect for couples, families or friends looking to relax in style in the Galápagos Villa Náutica is an elegant loft villa with a private Jacuzzi, spacious areas and a unique nautical design inspired by my Swiss and Galapagos roots. Located in a quiet residential neighborhood, it allows you to enjoy tranquility just a 12-minute walk from downtown Puerto Ayora. It combines comfort, authenticity, and the ideal atmosphere for discovering the islands and returning to rest in a cozy retreat.
LocationValueNearby

Samana Stay
Samana Stay is a spacious two-level family home in a quiet walkable neighbourhood, with beaches and the Charles Darwin Research Station nearby. Designed for comfort and long stays, it offers generous living areas, air-conditioned downstairs bedrooms, reliable Wi-Fi, and a fully equipped kitchen. The open living and dining space opens to a private garden with cut lava-rock pathways, creating a calm outdoor retreat and complete “entire home” privacy, ideal for families and eco-travellers.
LocationFamilyIndoor spaces

Exclusive, Modern and Cozy Accommodation
What makes our accommodation special is the perfect combination of comfort, cleanliness, and personalized attention that makes each guest feel right at home. We have taken care of every detail to offer a cozy, quiet space equipped with everything needed for an unforgettable stay. In addition, its excellent location allows you to easily enjoy the main attractions of the area, making it the ideal option for both relaxing and exploring.
LocationFamilyWalkability

Family Suite with Jacuzzi (included) photos 2026
Because we're one of the best Airbnbs.⚜️ Enjoy our Suite with your family or friends with tranquility, security, and modern and cozy comfort with everything included and quality service Enjoy our new Jacuzzi service ideal for all ages, parties, birthdays, etc. Enjoy a park in front of your stay (soccer, basketball, and children's games) Just a 3-4 minute drive to famous beaches, Las Grietas, La playa la Estación, Tortuga Bay.
ValueLocationAccuracy

El Galapagueño House
Come! Enjoy the simplicity of this magical, quiet, centrally-located, and private place with your partner, family, or friends! An ideal place to rest after visiting the most extraordinary tourist sites of the Galapagos Islands!!! 🏡🐢🏞️🏝️☀️🐚 We look forward to seeing you! 15 minutes' walk to the pier 100 meters from the entrance to Tortuga Bay Beach 20 meters from the tennis court
LocationFamilyBathroom

Casita Muyuyo - Galapagos Islands!
This bright, fully licensed two-bedroom Airbnb is perfect for families or friends seeking a safe, private, and comfortable stay. Located in a walled garden complex near town and just steps from the entrance to the Tortuga Bay trail, it's a peaceful retreat after a day of exploring the Galapagos. Please note this is a fully legal airbnb, with a license from the Ministry of Tourism
FamilyLocationHiking

Beautiful house with the best location in Santa Cruz
Relax with the whole family in this accommodation where tranquility is breathed. Located in one of the most exclusive and elegant neighborhoods of Puerto Ayora, just 200 meters away from the access to the Turtle Bay beach trail, very quiet and away from the noise of the shopping area. The house is close to the boardwalk and a few steps from restaurants and supermarkets.
ValueLocationAccess

Suite with AC + Kitchen near Charles Darwin Station
Ideal for exploring the island on foot, 7 minutes from the pier and a few minutes from Charles Darwin Station. Perfect for stays of 3 to 7 nights Excellent choice for travelers looking for comfort and location. Fast WiFi Comfortable access is located on the ground floor and the entrance is autonomous.
FamilyLocationSleep quality

Gps Villa
Perfect Villa for family or group of friends. Located in the best neighborhood on the island, very close to the main pier, restaurants, supermarkets, souvenirs. You can enjoy our villa and its facilities. We have a heated Jacuzzi with hydrojets, patio, solarium, living room, dining room, and kitchen.
ValueLocationLaundry

Vacation Home in Santa Cruz
House located in the El Eden neighborhood, next to the Pelicanbay neighborhood, 3 blocks from the island's tourist area and main avenues. Ideal private accommodation for solo travelers or couples. For people traveling with family, this house is suitable for up to 5 people.
FamilyValueLaundry
Popular amenities for Santa Cruz Island house rentals
House rentals with a pool

Panata’s Paradise with Pool!
FamilyLocationPool

Galapagos Retreat for 6 | Pool and Balconies

GALAPAGOS SHANGRI-LA 2 CASAS LEGAL&CLOSE TO BEACH
ValueLocationComfort

GALAPAGOS COTTAGES "Family House"
ValueFamilyCondition
Weekly house rentals

Casa 3 Gecko
FamilyValueTV

Luxury Residence in Santa Cruz, Galápagos Islands
FamilyLocationLaundry

Anita's house
LocationFamilyComfort

Vacation home in Galapagos, Santa Cruz
FamilyValueIndoor spaces

Vacation home
LocationHospitalityCleanliness

Bucanero's Nest. Santa Cruz Galapagos
LocationValueGetting around

House in Puerto Ayora near the mall
ValueLocationHospitality

CasaGalapagos Santa Cruz with Starlink Internet
LocationValueQuiet
Private house rentals

COSTA DEL SOL Galapagos Islands
LocationValueView

Modern and cozy house
ValueFamilyGetting around

A spacious and comfortable place
FamilyComfortKitchen

Peaceful 1 Bedroom Galápagos Island Retreat

Accommodation in Puerto Ayora
Indoor spacesGetting aroundHospitality

House in Galapagos
LocationGetting aroundHospitality

Serene & Spacious Oasis with Terrace
LocationHospitalityComfort

Peace Cottage: A haven of tranquillity.
LocationIndoor spacesView
Destinations to explore
- Puerto Ayora Vacation rentals
- Puerto Baquerizo Moreno Vacation rentals
- Galapagos Islands Vacation rentals
- Puerto Villamil Vacation rentals
- San Cristóbal Vacation rentals
- Isabela Island Vacation rentals
- San Cristóbal Island Vacation rentals
- Baltra Island Vacation rentals
- Tomás de Berlanga Vacation rentals
- Playa de Oro Vacation rentals
- El cascajo Vacation rentals
- Serviced apartment rentals Santa Cruz Island
- Hostel rentals Santa Cruz Island
- Guesthouse rentals Santa Cruz Island
- Hotel rooms Santa Cruz Island
- Pet-friendly rentals Santa Cruz Island
- Private suite rentals Santa Cruz Island
- Family-friendly rentals Santa Cruz Island
- Rentals with pools Santa Cruz Island
- Apartment rentals Santa Cruz Island
- Rentals with a hot tub Santa Cruz Island
- Rentals with beach access Santa Cruz Island
- Waterfront rentals Santa Cruz Island
- Rentals with breakfast Santa Cruz Island
- Bed and breakfasts Santa Cruz Island
- House rentals Galápagos
- House rentals Ecuador





