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Vacation rentals in Santa Cruz Island

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz Island

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious rooftop terrace features a checkered tile pattern, with seating areas and a large umbrella for shade. Panoramic ocean views are provided, showcasing multiple boats in the water and the coastal landscape, creating a serene outdoor space for relaxation.
Townhouse in Puerto Ayora
4.93 out of 5 average rating, 134 reviews

Galapagos Family Vacation 3 BR. Ocean View

This unique luxury townhouse combines high-tech amenities with spacious comfort. (First Floor) The great room features a state-of-the-art kitchen, a generous dining table, and a cozy living area with a library, high-speed Wi-Fi, and a large desk. (Second Floor) Large staterooms generously sized, air-conditioned, soundproof, impeccably clean, each with private restrooms. (Third Floor)The rooftop terrace offers breathtaking ocean views, featuring ample seating and hammocks for a perfect getaway.

Top guest favorite
Apartment in Puerto Ayora
4.96 out of 5 average rating, 85 reviews

Bright and cozy 2 bedroom home away from home

Kick back and relax in this calm, stylish space. A bright and comfortable two-bedroom apartment in the heart of the Galapagos, Santa Cruz Island. Surrounded by vegetation, it is situated only four blocks from the main street, five minutes walk from the main dock, and at the entrance of Tortuga Bay. AMAZING terrace with outside dining areas. Perfect for couples or a small group of friends. It offers working spaces, a kitchen, a washing machine, all you need to have your own home in the Galapagos.

Top guest favorite
Apartment in Puerto Ayora
4.95 out of 5 average rating, 182 reviews

Planet House Apt1: modern, spacious great location

Beautiful legally registered property, with partial ocean view and wonderful fresh breeze. Our apartment is located two blocks away from Charles Darwin Avenue. Guests can enjoy a leisurely walk to main attractions like the Charles Darwin Research Station and beach, great restaurants, cafés, shops, bike rental, dive shops, tour operators and more. Great options for guests seeking flexibility, comfort and value for money. The bedroom has AC, the living area benefits from a nice sea breeze.

Guest favorite
Home in Puerto Ayora
5 out of 5 average rating, 48 reviews

Villa Náutica

Welcome to your cozy home in the Galápagos Islands! Escape to my enchanting villa loft, where my Swiss and Galápagos roots intertwine, experience the perfect harmony of vibrant island life and cozy Swiss vibes. With bright, airy interiors and unique nautical touches, my space invites you to unwind in style. Located just an 10 min stroll from the Charles Darwin Ave. I’m here to ensure your stay is magical. Come & discover the beauty of the Galápagos—your unforgettable journey awaits!

Top guest favorite
Cabin in Santa Cruz
4.96 out of 5 average rating, 208 reviews

Casa Vikingo • A Unique, Secluded Highland Cabin

Casa Vikingo blends Scandinavian-inspired design with tropical modernism, creating airy, climate-responsive spaces that immerse you in the unique highland nature of Galápagos. Under the shade of endemic guayabillo trees, the cabin blends seamlessly into the landscape while resting on a lava rock base built from materials sourced on site. The cabin offers some of the most beautiful views in the area, which you can admire directly from the king-sized bed or the private plunge tub.

Guest favorite
A suspended bed is featured with two plush pillows, set against a backdrop of wooden beams and large windows. Natural light filters through the space, illuminating the unique architecture and the surrounding greenery visible outside.
Apartment in Puerto Ayora
4.83 out of 5 average rating, 175 reviews

Oceanview Suite: Nest House

Welcome to our one-of-a-kind, bird’s nest-inspired suite in Puerto Ayora, Galapagos. Enjoy: ๏ Ocean views from your private balcony ๏ Cozy hanging bed for ultimate relaxation ๏ Artistic tree staircase ๏ Fully-equipped kitchen ๏ High-speed Wi-Fi (120 Mbps) and workspace ๏ Ventilated living space The bathroom is located just below the suite, offering added privacy. Stroll to nearby cafes, bakeries, and restaurants. Let us help you discover the best of the islands!

Top guest favorite
The interior suite features high ceilings and large windows allowing natural light. A wooden kitchen area is complemented by a small dining space, and two spacious beds are styled with patterned bedding. The connecting outdoor space reveals glimpses of the lush garden.
Bungalow in Puerto Ayora
4.9 out of 5 average rating, 303 reviews

Bright Garden Bungalow in a quiet neighborhood.

Sunshine filled, bright garden suite, next to the entrance to the Galapagos National Park and the Charles Darwin Station, and a few blocks away from some of the best restaurants, art galleries and bars in town. Located on the far end of one of Puerto Ayora's main streets, accessible to the road but removed enough to be isolated from the urban noise. An AC cools the suite when needed in the warmer months, and it’s screened windows are the alternative as well .

Guest favorite
A bright kitchen is visible, featuring wooden cabinetry and a granite countertop. Large windows allow natural light to fill the space. An induction stove and refrigerator are included, along with a coffee maker and other kitchen essentials. A small eat-in breakfast bar with stools is present.
Apartment in Puerto Ayora
4.96 out of 5 average rating, 217 reviews

Paloverde: Cute and bright two-level apartment!

This recently renovated, fully licensed Airbnb apartment spans two levels with a private entrance on a quiet street. Downstairs features a garden patio, a cozy living room with a workspace, a king bedroom with A/C, and an ensuite bathroom. Upstairs you'll find a bright, fully equipped kitchen with a breakfast bar and a balcony for outdoor dining overlooking the garden. Please note that this is a legal rental licensed by the Ministry of Tourism

Top guest favorite
Apartment in Puerto Ayora
4.92 out of 5 average rating, 73 reviews

Beautiful suite with ocean view. 1 or two guests.

Éste alojamiento único, se encuentra en el tercer piso, tiene una hermosa vista al mar, a solo 3 minutos de la playa ¨La Estación¨y la ¨Fundación Charles Darwin¨, es cómoda y acogedora, lejos del ruido urbano, cuenta con internet de alta velocidad. Se encuentra además sobre una cafetería con deliciosa comida sana y artesanal, donde los fines de semana se desarrollan eventos culturales y es un espacio ideal para coworking.

Guest favorite
A charming exterior of a private accommodation is presented, featuring a rustic wooden door framed by lush greenery and colorful flowering plants. The natural stone pathway leads to the entrance, enhancing the inviting atmosphere of the serene outdoor space.
Home in Puerto Ayora
4.89 out of 5 average rating, 152 reviews

El Galapagueño House

Come! Enjoy the simplicity of this magical, quiet, centrally-located, and private place with your partner, family, or friends! An ideal place to rest after visiting the most extraordinary tourist sites of the Galapagos Islands!!! 🏡🐢🏞️🏝️☀️🐚 We look forward to seeing you! 15 minutes' walk to the pier 100 meters from the entrance to Tortuga Bay Beach 20 meters from the tennis court

Superhost
An inviting interior space is showcased, featuring light wood accents and large glass doors. A hammock is suspended between two rooms, creating a relaxed ambiance. Natural light filters through sheer curtains, illuminating the open layout with soft shadows on polished tile floors.
Apartment in Puerto Ayora
4.91 out of 5 average rating, 155 reviews

Casa Tuna

Enjoy your vacation in Galapagos in a beautiful apartment located in a residential sector of Puerto Ayora, with a unique style that combines wood with white, comfortable rooms with TV, air conditioning and private bathroom. In addition, with a large terrace that will make your stay unforgettable.

Superhost
Apartment in Puerto Ayora
4.75 out of 5 average rating, 55 reviews

Ocean 6 Breeze Terrace

Ubicado a pocos pasos de la bahía, este acogedor departamento te permite disfrutar del encanto de la isla caminando hacia el malecón, restaurantes, bares y el famoso muelle de pescadores. Una zona tranquila y segura, ideal para relajarse después de un día de aventura.”

Popular amenities for Santa Cruz Island vacation rentals

Frequently Asked Questions

  • When is the best time to visit Santa Cruz Island?

    The climate on Santa Cruz Island is often comfortable year-round, with dry and warm conditions frequently suggested for outdoor activities. Many travelers appreciate the wildlife viewing opportunities available during alternating wet and dry seasons.

  • What are some things to do near Santa Cruz Island?

    Explore locally guided wildlife excursions, visit the Charles Darwin Research Station, and wander through traditional markets in nearby Puerto Ayora. Activities such as snorkeling, hiking, and bird spotting are frequently suggested for travelers.

  • How is the weather near Santa Cruz Island?

    Santa Cruz Island typically has mild tropical conditions, with warm temperatures and occasional rainfall distributed throughout the year. Visitors often experience comfortable days and cooler evenings, so packing for variable weather is suggested.

  • What is the history of Santa Cruz Island?

    Santa Cruz Island has a history rooted in scientific research, conservation, and local communities working to sustain unique ecosystems. Its past includes the development of research stations and ongoing efforts to protect endemic species.

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