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Places to stay near Santiago Island

Book unique vacation rentals, homes, and more on Airbnb

Top-rated vacation rentals near Santiago Island

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Apartment in Puerto Ayora
4.97 out of 5 average rating, 78 reviews

Bright and cozy 2 bedroom home away from home

Kick back and relax in this calm, stylish space. A bright and comfortable two-bedroom apartment in the heart of the Galapagos, Santa Cruz Island. Surrounded by vegetation, it is situated only four blocks from the main street, five minutes walk from the main dock, and at the entrance of Tortuga Bay. AMAZING terrace with outside dining areas. Perfect for couples or a small group of friends. It offers working spaces, a kitchen, a washing machine, all you need to have your own home in the Galapagos.

Top guest favorite
The sitting area features a modern gray sofa adorned with decorative pillows and is complemented by a wooden coffee table. Artwork hangs on the walls, and large glass doors provide ample natural light and views of a private balcony and the surrounding greenery.
Apartment in Puerto Ayora
4.91 out of 5 average rating, 202 reviews

Planet House Apt2 Sunny 1 BR flat. Great location

This is a beautiful legally registered property, with great views and wonderful fresh ocean breeze. Our apartment is located two blocks away from Charles Darwin Avenue. Guests can enjoy a leisurely walk to main attractions like the Charles Darwin Research Station and beach, great restaurants, cafés, shops, dive shops, tour operators and more. Great option for guests seeking flexibility, comfort and good value. The bedroom has AC, however the living area only benefits from a nice sea breeze.

Top guest favorite
A bright common area features two comfortable sofas with decorative cushions and a wooden coffee table at the center. A TV is placed on an easel, and vibrant wall art adds character to the space. The open layout is enhanced by wooden beams and pendant lighting.
Apartment in Puerto Ayora
4.96 out of 5 average rating, 185 reviews

Updated apartment close to centre of town

Our private, bright, spacious apartment is centrally located in Puerto Ayora close to Darwin Avenue. Restaurants, shops, Darwin Station and the main passenger pier are just a few minutes walk away. The apartment is equipped with wifi, large kitchen with fridge, induction stovetop and microwave, and a large common area. It is good for couples, families or small groups. There are two bedrooms with A/C and sofa beds so a family group can easily be accommodated. Patio available upstairs.

Top guest favorite
An airy open space showcases a wooden dining area with three stools and a brightly lit kitchen in the background. Two woven light fixtures hang from above, while a large potted plant adds a touch of greenery to the warm-toned interior.
Home in Puerto Ayora
5 out of 5 average rating, 42 reviews

Villa Náutica

Welcome to your cozy home in the Galápagos Islands! Escape to my enchanting villa loft, where my Swiss and Galápagos roots intertwine, experience the perfect harmony of vibrant island life and cozy Swiss vibes. With bright, airy interiors and unique nautical touches, my space invites you to unwind in style. Located just an 10 min stroll from the Charles Darwin Ave. I’m here to ensure your stay is magical. Come & discover the beauty of the Galápagos—your unforgettable journey awaits!

Top guest favorite
A comfortable sleeping area is featured with a spacious bed adorned with patterned bedding in soft blue tones. Natural light illuminates the room, highlighting the smooth, neutral wall and simple wooden furniture.
Apartment in Puerto Villamil
4.9 out of 5 average rating, 10 reviews

Casita Limon Fully equipped private Loft. Suite #4

Fully equipped centrally located Suite on the 1st floor. Fully equipped kitchen Sliding door private entrance with digital lock No stairs General laundry for all guests (shared space) Washing and drying machines + hand washing area. Starlink internet and access points on the entire property (inside and outside) so you never loose your connection. Hot water with solar panels Reserve osmosis potable water in the flat and in the outside general chilling area. Comfy bed clothing!

Guest favorite
A welcoming living area features sleek furniture and a natural wood floor that reflects light. Two modern chairs are positioned around a minimalistic coffee table on a round woven rug. Large double doors open to a balcony, offering scenic views of the surroundings.
Apartment in Puerto Ayora
4.84 out of 5 average rating, 170 reviews

Oceanview Suite: Casa Nido

Welcome to our one-of-a-kind, bird’s nest-inspired suite in Puerto Ayora, Galapagos. Enjoy: ๏ Ocean views from your private balcony ๏ Cozy hanging bed for ultimate relaxation ๏ Artistic tree staircase ๏ Fully-equipped kitchen ๏ High-speed Wi-Fi (120 Mbps) and workspace ๏ Ventilated living space The bathroom is located just below the suite, offering added privacy. Stroll to nearby cafes, bakeries, and restaurants. Let us help you discover the best of the islands!

Top guest favorite
A spacious rooftop terrace features a checkered tile pattern, with seating areas and a large umbrella for shade. Panoramic ocean views are provided, showcasing multiple boats in the water and the coastal landscape, creating a serene outdoor space for relaxation.
Townhouse in Puerto Ayora
4.92 out of 5 average rating, 132 reviews

Casa Marina, Galapagos

Casa Marina Galapagos is a unique contemporary, 1.400 square feet, 3 floor townhouse located in the heart of Santa Cruz Island in Galapagos. This family friendly home is suitable for everyone even for your corporation events. We offers spacious rooms with a modern kitchen, large dining table, and comfortable seating in the living area. The roof top terraces with ocean view & highland are astonishing. We welcome you to engage your hearts for an experience of a lifetime.

Top guest favorite
Cabin in Santa Cruz
4.96 out of 5 average rating, 203 reviews

Casa Vikingo • A Unique, Secluded Highland Cabin

Casa Vikingo blends Scandinavian-inspired design with tropical modernism: airy, climate-responsive spaces that embrace nature, panoramic ocean views, and wildlife encounters just steps from your door. Set in the highlands on the sunny east side of Santa Cruz, this off-grid cabin borders the national park and sits on 2.5 acres of private land. Ideal for adventurous couples, honeymooners, and nature lovers seeking privacy. Taxi pickup can be arranged; no car required.

Guest favorite
A bright kitchen is visible, featuring wooden cabinetry and a granite countertop. Large windows allow natural light to fill the space. An induction stove and refrigerator are included, along with a coffee maker and other kitchen essentials. A small eat-in breakfast bar with stools is present.
Apartment in Puerto Ayora
4.96 out of 5 average rating, 208 reviews

Paloverde: Cute and bright two-level apartment!

This recently renovated, fully licensed Airbnb apartment spans two levels with a private entrance on a quiet street. Downstairs features a garden patio, a cozy living room with a workspace, a king bedroom with A/C, and an ensuite bathroom. Upstairs you'll find a bright, fully equipped kitchen with a breakfast bar and a balcony for outdoor dining overlooking the garden. Please note that this is a legal rental licensed by the Ministry of Tourism

Top guest favorite
A charming two-story house features a warm façade with large windows and a balcony. Surrounding greenery includes a well-kept garden, while a wooden fence encloses the area. Soft lighting creates a welcoming ambiance in the evening, enhancing the home's inviting exterior.
Apartment in Puerto Ayora
5 out of 5 average rating, 47 reviews

Bright Loft/Suite by Encantadas

Modern and bright loft, fully equipped with everything you may need. It's air conditioned, has free wifi, a hot shower, hotel amenities, and more, all just a few minutes from the main pier. Your studio has a small terrace, and on the second floor, there's a perfect desk for remote working. With over 11 years in the Airbnb industry, we understand our guests' needs. Explore the Galapagos and relax in your own private studio.

Guest favorite
A charming exterior of a private accommodation is presented, featuring a rustic wooden door framed by lush greenery and colorful flowering plants. The natural stone pathway leads to the entrance, enhancing the inviting atmosphere of the serene outdoor space.
Home in Puerto Ayora
4.88 out of 5 average rating, 142 reviews

El Galapagueño House

Come! Enjoy the simplicity of this magical, quiet, centrally-located, and private place with your partner, family, or friends! An ideal place to rest after visiting the most extraordinary tourist sites of the Galapagos Islands!!! 🏡🐢🏞️🏝️☀️🐚 We look forward to seeing you! 15 minutes' walk to the pier 100 meters from the entrance to Tortuga Bay Beach 20 meters from the tennis court

Superhost
A spacious bedroom is complemented by large windows, allowing natural light to filter through. A small dining area with a round table and two chairs is visible, surrounded by greenery. A television is mounted on a shelf, enhancing the functional design of the space.
Apartment in Puerto Ayora
4.81 out of 5 average rating, 227 reviews

Galapagos Suite Sol

A beautiful duplex full of light and surrounded by gardens, it's located in a quite and residential neighborhood of Puerto Ayora, Santa Cruz Island. Within walking distance to the seafront, the Charles Darwin Station and the town centre! (5-10 min) you can easily access all tourist sites and find privacy in a beautiful home.

Popular amenities for vacation rentals near Santiago Island

Destinations to explore

  1. Airbnb
  2. Ecuador
  3. Galápagos
  4. Santiago Island