Vacation rentals in San Antonio

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Top-rated vacation rentals in San Antonio

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

A single-story house is nestled beneath a large tree, featuring a tiled roof and a covered parking area. Surrounding greenery includes bushes and ornamental plants, enhancing the natural setting. The house is positioned to provide a sense of privacy and tranquility.

Home in Chitre

4.87 out of 5 average rating, 62 reviews

Country House Like in the City / La Casita

Casa fresca, con árboles y naturaleza. Áreas amplias para descansar. Ubicación céntrica, cerca de malls, restaurantes, estación de buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Ahora, Chitré, tiene un problema con el agua: no está potable; tenemos 50% de lo habitual, a veces estamos sin agua por algunas horas. Por favor, consulten antes de reserar.

A bright and airy room features two full-size beds with crisp white linens and decorative pillows. A wooden dining table with four chairs is positioned nearby. Fresh towels are neatly arranged on the beds. A small kitchenette is subtly integrated into the space.

Apartment in Los Canelos

4.71 out of 5 average rating, 41 reviews

Salamanca Loft

Este hermoso apartamento esta ubicado en el centro de todo Panamá en la hermosa provincia de Herrera, vía interamericana, a pocos minutos de varias ciudades como Chitré, Aguadulce y Santiago. En un ambiente tranquilo, rodeado de árboles. Si corren con suerte podrán observar desde lejos las hermosas iguanas que se pasean por las ramas mas altas. Pueden apreciar al caer la tarde una hermosa puesta del sol. Justo al frente, hay cafetería, también hay pizzerías a domicilio y restaurantes.

Guest favorite

A wooden decoration is positioned on the bedspread, showcasing the words 'With Love Made in Panama.' The bed features a wooden headboard, complemented by a bedside lamp. Soft blankets and neutral-colored walls create a cozy sleeping environment.

Vacation home in Chitre

4.94 out of 5 average rating, 67 reviews

CASA EdditA ° Cozy house in Chitré

° CASA EDDITA ° Fully equipped house for your enjoyment. Spacious, cool, and cozy in one of the best-located residential areas of Chitré, close to everything: supermarkets, casinos, and a bus terminal. If you are thinking of touring Azuero, we suggest you stop at Casa Eddita, visit downtown Chitré, its handicrafts, cathedral and its variety of typical foods; from here you will be only 1:30 hr from the best beaches of Azuero in Pedasí (Playa Venao and Isla Iguana) Welcome!

Guest favorite

The house exterior features a warm peach-colored facade with a large white-framed window. Tropical palm trees and vibrant flowering shrubs border the front, providing a refreshing touch to the entrance.

Home in Chitre

4.82 out of 5 average rating, 74 reviews

NinaHouse, spacious and cool house in Chitré.

House just for you, now with a water tank! Up to 7 people, spacious and in one of the best areas of Chitré, quiet and family-friendly, access to the pool in the social area, parks and courts, close to everything: supermarkets, casino, bus; come to Chitre and enjoy typical meals, crafts; plan your walks and visit the best beaches: Pedasi, Venao, Isla Iguana, you can work from NinaHouse with fast internet. We now have air conditioning in the living room for your comfort.

Superhost

Home in Santiago

4.95 out of 5 average rating, 20 reviews

House minutes from Santiago, U Latina, HospChichoF.

Spacious, comfortable and fully equipped house in a strategic location in Santiago. Perfect for all types of guests: families, business travelers, students, people coming to medical appointments or those looking for a quiet and accessible space. The house is located very close to Dr. Chicho Fábrega Hospital, Clínica Norte, U.Latina, Oxford School, supermarkets, pharmacy, restaurants, and minutes from downtown Santiago. A safe place for short and long stays.

Top guest favorite

Home in Canto del Llano

5 out of 5 average rating, 7 reviews

Peaceful home w/ spacious living & office area

Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

A cozy corner is shown with a light-toned futon, paired with a small wooden table and two modern chairs. Natural light enters through two windows, complementing the warm wooden paneling on one wall.

Condo in Panama City

4.63 out of 5 average rating, 32 reviews

Departamento 2E - BEST place in town.

Accessible apartment in the heart of Santiago, located 300m from the Central Bus Station and within walking distance of supermarkets and businesses. With good distribution of space, fresh and illuminated and with all basic services. The apartments provide a harmonious balance in the middle of the rush characteristic of the city, perfect for stays of families, friends, professionals, couples.

Guest favorite

The two-story colonial house is showcased with a white facade and wooden accents. Decorative balconies with railings are present at the front, along with several potted plants adding color. The street is lined with other buildings, under a clear blue sky dotted with clouds.

Cottage in Parita District

4.8 out of 5 average rating, 44 reviews

Colonial House in Parita

Discover the charm of Parita from a comfortable and spacious home, perfect for large groups. Located in the picturesque and peaceful town of Parita, in the Herrera Province, just 12 minutes from Chitré, this spacious home is the ideal place to immerse yourself in the history and culture of a historic colonial-era town.

Superhost

A small dining area is featured with a round table and two folding chairs. Large windows offer views of lush greenery outside, while sheer white curtains partially filter natural light.

Apartment in Santiago

4.88 out of 5 average rating, 8 reviews

d'rosas apartamentos 3PB

Discover the comfort in our cozy home in the heart of Santiago, Veraguas. Just a 5 minute walk from downtown, you'll enjoy a well-equipped space that includes all the necessary amenities for a relaxing stay. Ideal for exploring local culture and resting after a day of adventure. We look forward to seeing you!

Guest favorite

A spacious living area is furnished with two orange sofas and a small black coffee table. Natural light filters through sheer curtains, illuminating the neutral-toned walls. A mounted television is visible, and a refrigerator is located in the background, suggesting a welcoming space for relaxation.

Home in Chitre

5 out of 5 average rating, 8 reviews

Centrally located and well-equipped, accommodates 10 people

Very central steps from supermarket, banks, hospitals. Large spaces, a patio, and all the amenities so you can enjoy your stay. A/C in all areas. Comfortable sleeping capacity for 10 people. We are Pet Friendly. Parking for 2 cars under cover and up to a third car in the front outside part of the house.

Superhost