Vacation rentals in Saint Ann

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Top-rated vacation rentals in Saint Ann

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost

A staircase with white banisters and wooden steps leads to the upper level. The exposed antique brick wall provides historical character to the space. A woven area rug is positioned at the base of the stairs, complementing the warm wooden flooring.

Loft in Saint Charles

4.84 out of 5 average rating, 148 reviews

Main Street Historic Loft

DanielleRating, 5 stars1 month ago

This places was excellent. We enjoyed our stay. The place was cozy and comfortable, had what we needed. We were there on a Friday night…be warned it can get a little noisy outside so if that bothers you, then staying on a fairly busy street with lots of businesses probably isn’t for you. We weren’t bothered at all. Lots of great stores and restaurants on the same stretch of road. Definitely enjoyed our stay.

Top guest favorite

A sunlit screened-in porch features white wicker chairs with purple cushions positioned on polished wooden floors. Two hanging ferns provide greenery above, while a wooden swing adds a cozy seating area. Large windows allow for ample natural light and a view of the outside.

Home in Grafton

5 out of 5 average rating, 23 reviews

Stay In A Piece Of History

ElizabethRating, 5 stars1 day ago

Had a wonderful time in downtown Grafton for my daughter’s 21st birthday. The house is in a great location for walking distance to all attractions, restaurants, bars, shops and more. It was nice to not have to drive anywhere after celebrating her birthday! We will definitely be back!

Top guest favorite

A modern kitchen is equipped with stainless steel appliances, including a gas stove and dishwasher. Open shelving showcases dishes, while a well-organized layout features several drawers. Natural light enters through small windows above the sink, and sleek countertops complete the space.

Home in South Hampton

5 out of 5 average rating, 41 reviews

Blair's Amazing House Sleeps 10 - 5 Beds - 2 Bath

HowardRating, 5 stars2 weeks ago

The house is well laid out, clean, and in a nice neighborhood. The location is convenient, safe, and quiet. The owner was responsive and flexible. While there is a garage, we never used it as there was always on-street parking right in front of the house. Everyone in our party thought it was a great choice!

Guest favorite

A fenced yard is featured, showcasing a blend of wooden panels in various tones. Flowering plants line the edge, with vibrant blooms among greenery. A putting green area is visible in the foreground, accompanied by a paved pathway leading to outdoor seating.

Home in St. Louis

4.89 out of 5 average rating, 207 reviews

Home away from Home St. Louis Cnty Ladue Schools

RaphaëlleRating, 5 stars3 weeks ago

Lisa was great! I needed a calm, peaceful and clean place for 2 weeks to recover from a surgery and her house was perfect. She was flexible with my arrival and departing time as I got updates from my surgeon and always worked it out with me, even last minute. There's a nice little park and neighborhood around and the house is very comfortable. Highly recommend!

Vacation rentals for every style

Get the amount of space that is right for you

Hotels

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Homes

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Popular amenities for Saint Ann vacation rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Stay near Saint Ann's top sights

Walmart Supercenter14 locals recommend

ALDI8 locals recommend

Avis Car Rental6 locals recommend

Lambert Airport Terminal # 1 station6 locals recommend

Chimi's Fresh-Mex5 locals recommend

Lambert Airport Terminal # 2 station5 locals recommend

Other great vacation rentals in Saint Ann

Guest favorite

A sunlit yard features a circular pool with clear blue water, complemented by a green inflatable and surrounded by lush greenery. Comfortable seating areas with striped cushions and vibrant umbrellas provide shaded spots nearby, creating an inviting outdoor space for relaxation.

Home in St. Louis

5 out of 5 average rating, 5 reviews

home away from home

AshleyRating, 5 stars8 months ago

Took a mini vacay to St Louis with my mom & the kiddos. 3 adults & 2 children had plenty of space for sleeping. The pool & hot tub were so relaxing. It felt so homey. We were offered fresh produce from the garden. Lots of pots & pans if you like to cook while traveling. The bar was nice if you like to relax with a drink. Everyone loved the Pac-Man machine! Tons of at home amenities like streaming channels, coffee maker, potato chips, toys for the kiddos, giant Jenga set, etc. Private & safe location. Only 20-30 mins driving to the heart of St Louis. We really enjoyed our weekend and would recommend this home to anyone needing a family spot to relax.

Top guest favorite

A stylish bar area is presented with four black, cushioned stools set around a granite-topped counter. The backdrop features warm wooden paneling that complements the sleek black brick base, creating a modern yet cozy atmosphere.

Home in Ballwin

5 out of 5 average rating, 29 reviews

Perfect Getaway 3BR/3BA Home

JohnRating, 5 stars2 weeks ago

Another perfect stay at Perfect Getaway. The home was very clean and the host communication was quick and easy. Great neighborhood and great location. I highly recommend.

Guest favorite

The exterior of a tranquil retreat is framed by lush greenery and vibrant flower beds. A gravel path leads to the building, which features a sloped roof and large windows. The surrounding landscape includes various plants, contributing to the peaceful environment.

Cottage in Sugar Loaf Township

4.92 out of 5 average rating, 71 reviews

Cheerful one bedroom cottage on a horse farm

SavannahRating, 5 stars2 months ago

It was so nice to get away and relax for the night at the cottage! It was so peaceful! Water pressure in the shower was amazing and the bed was so comfortable! Will definitely stay again!

A compact kitchen area is showcased, featuring a gray cabinet base and a marbled countertop. Two sinks are integrated into the counter, with a black faucet above. A microwave rests beside a potted plant on the countertop, while a round shelf provides additional storage.

Apartment in St. Louis

5 out of 5 average rating, 4 reviews

Holly Hills hidden gem

RobertaRating, 5 stars5 months ago

Tracey has created a lovely little haven. Her space exudes peace and comfort and provides all one could want for a short or longer stay. The park across the street was a great place to take my dog for walks. Grocery and other stores are nearby and the freeway is easily accessible. Tracey is a welcoming and thoughtful host.

Superhost

A spacious living area features a white leather sectional arranged around a low table. Natural light floods the room through multiple windows. Contemporary artwork of ocean waves adorns the wall, complementing sleek furnishings and open access to the adjoining kitchen and dining area.

Home in St. Louis

4.82 out of 5 average rating, 66 reviews

Modern Luxury w/Saltwater Pool / ABODEbucks

BrandonRating, 5 stars2 weeks ago

Had a wonderful stay at this Airbnb! The place was exactly as described—clean, comfortable, and thoughtfully decorated. The host was incredibly welcoming and responsive, making sure everything went smoothly. The location was perfect for exploring the area, and I truly felt at home during my stay. I would absolutely stay here again and highly recommend it to anyone looking for a relaxing and enjoyable visit! The work room was a plus.

Guest favorite

The exterior view of the Pineapple House showcases a two-story structure with a light-colored facade, featuring a welcoming entrance surrounded by landscaped grass. Pathways lead from the entryway, and outdoor seating options are visible on the porch, complemented by decorative hanging plants.

Home in Grafton

4.81 out of 5 average rating, 16 reviews

Main Street+River View+3 Bedrooms

KayRating, 5 stars4 months ago

We really enjoyed staying at the Pineapple Cottage and very much appreciated that Jacqui had added additional knives, silverware, cookware to the kitchen after our last stay as we needed to prepare some dishes for a family thanksgiving get together in town. The living room is spacious and the bedrooms very comfortable. We had a few issues with the heating and Jacqui was responsive to our concerns.

An outdoor deck area features two red chairs around a small round table. A door with multiple glass panels provides access to the interior. The exterior walls are painted in contrasting shades of red and blue, with windows allowing natural light to brighten the space.

Condo in Grafton

4.76 out of 5 average rating, 54 reviews

One bedroom condo with great riverview.

ColinRating, 5 stars1 day ago

Great place. Great location. Daniel was super nice. Happened to be visiting on a weekend when the flea market was in session! Fun people and watching and fun visiting the flea market. Opposite end of town from the activities of the more active bars, but absolutely walkable and quiet when you wanted to get away from it all.