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Vacation rentals in Pickens County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Pickens County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Home in Pickens
4.94 out of 5 average rating, 204 reviews

Mountain Views, Peaceful Waterfall 3 King Bedrooms

The peaceful sounds of a Rushing Waterfall welcome you to “Mountain Paradise”. Surrounded by 500 acres of forest and waterfalls, you have the ultimate level of privacy. --> 10 min to Table Rock State Park --> 3 min to The Rock Golf Club --> 26 min to Devils Fork State Park (Lake Jocassee) --> 20 min to Downtown Pickens Lavish is privacy w/ 3 separate KING bedrooms and 3 Full Baths! --> Fully stocked kitchen --> High speed internet --> Smart TVs + free Netflix & YouTube TV --> 4 parking spots

Top guest favorite
A porch swing is set on a wooden deck, adorned with plush cushions featuring intricate patterns. Lush greenery and colorful flowers are visible in the background, adding vibrancy to the serene outdoor setting.
Guesthouse in Six Mile
4.97 out of 5 average rating, 173 reviews

Your Charming Country Cottage

Whether you need a country getaway or a place to lay your head after a football game, our cottage in the foothills of upstate SC is the perfect spot for both. You’ll find us tucked away just outside the quaint little town of Six Mile, 10 miles north of Clemson University and in close proximity to 3 of the upstate's favorite lakes: Lake Keowee, Lake Jocassee and Lake Hartwell. Here you’ll enjoy the serenity of country life without feeling “too far out" or away from all the upstate has to offer.

Top guest favorite
A gravel pathway leads to the front porch of the cabin, lined with decorative outdoor lights. The cabin is framed by tall trees, offering a serene natural setting. The porch features a covered area, inviting guests to enjoy the outdoors.
Cabin in Pickens
4.96 out of 5 average rating, 139 reviews

Hagood Mill Hideaway

Video tour on YouTube "Hagood Mill Hideaway-Air BNB in Upstate South Carolina by Cody Hager Photography". This cabin near Historic Hagood Mill with private fishing pond is perfect for a weekend of relaxing on the porch or while sitting the fire pit. The cabin has a kitchen and gas grill . Smoking, vaping, e‑cigarettes are NOT allowed in the cabin, porch nor the property. We provide a gate pass to Table Rock just 15 min. away. (If the pass is lost during your stay, you will be charged $105 fee)

Guest favorite
The exterior of a charming brick house is framed by lush greenery. A stone pathway leads to the entrance, flanked by well-maintained shrubs and trees. Large windows allow natural light to fill the living spaces inside, providing a welcoming exterior view.
Home in Pickens
4.97 out of 5 average rating, 115 reviews

Welcome to Downtown Pickens

This beautiful brick home located on a spacious lot is waiting for you! Your family will be close to everything when you stay at this centrally-located place. 3 spacious bedrooms and 1.5 baths will make life a breeze. Dine or relax on the covered patio while the kids play in the gently sloping private backyard. Your stay on West Main St will be a dream with all the amenities of downtown Pickens being in walking distance. You are also only 20 minutes from all Greenville or Clemson has to offer.

Guest favorite
A spacious living area showcases wooden walls and ceilings. A kitchen island with a granite countertop provides ample space, accompanied by a wooden stool. A sofa faces a stone fireplace, while a dining table is set nearby. Natural light filters through patterned curtains.
Home in Pickens
4.86 out of 5 average rating, 102 reviews

Country Apple Cottage

Welcome to our cozy cottage in Pickens, SC, nestled in the beautiful foothills of the Upstate! This cottage is conveniently located just 40 minutes from Greenville and 20 minutes from Clemson. The cottage features a comfortable living space, a well-equipped kitchen, a serene bedroom, and a private outdoor area where you can relax and enjoy the fresh mountain air. With hiking trails, waterfalls, and charming small towns just a short drive away, we can't wait to welcome you to our cottage.

Guest favorite
A cozy living area features a stone fireplace flanked by windows, allowing natural light to illuminate the space. A comfortable sofa is arranged around a small table, accompanied by a chair. A TV is mounted above the fireplace for entertainment.
Condo in Salem
4.97 out of 5 average rating, 144 reviews

Beautiful Lake Keowee Condo with great Amenities

"Boasting lake views, a fully equipped kitchen, and resort-style amenities, this 2-bedroom, 2-bath Salem vacation rental condo in Keowee Key will have you experiencing the true meaning of life on the lake. Cool off with a dip in the community's outdoor pool which sits right next to the marina where you can rent a boat for a day out on the water. Tee up a round of golf on the renovated 18-hole course, walk along the trails of Oconee State Park, or catch a football game at Clemson University!"

Top guest favorite
A charming cabin is nestled among tall trees, accessed by a stone path. Warm string lights adorn the porch area, creating a welcoming glow. Fallen leaves blanket the ground, complementing the natural surroundings and inviting a sense of tranquility.
Cabin in Pickens
4.98 out of 5 average rating, 256 reviews

The Romantic Greystone Cottage

Follow the enchanting stone path to a private getaway where romance and connection await. Enjoy the ambiance of the starlit sky while cuddled up on the hammock or around the fire. Cozy up on the king-size bed and relish every moment of your stay. Indulge in a bottle of wine and relax by soaking in the luxurious claw-foot tub. Wake up to the tranquil sounds of the forest, savoring the morning with coffee on the porch. Escape the everyday and embrace what matters most at The Greystone Cottage.

Top guest favorite
A serene bedroom features a four-poster bed draped with soft textiles, complemented by cozy fur accent pieces. Warm lighting creates a relaxing ambiance, while decorative wall frames and patterned rugs enhance the inviting atmosphere. Multiple windows allow natural light to filter in.
Home in Easley
4.99 out of 5 average rating, 117 reviews

Comfy, cozy duplex apt in old home downtown Easley

Comfortable, CLEAN, safe, serene, remodeled duplex apartment w/private entrance thru back of home - 20 mins to Gville/Clemson. Stocked for cooking. Near hiking, climbing, kayaking, diving, fishing, restaurants, breweries, pubs, theatres, museums, hospitals, live music venues, shopping, universities, and churches. Come home to comfy robes and rooms designed for relaxation. Note: Easley has a train track downtown - a few blocks away. This is important to note. Self check-in thru passcode

Top guest favorite
A bright living space features a comfortable gray sectional sofa with decorative pillows. A small wooden table sits beside it. A sleek chair with wooden legs offers additional seating, while a flat-screen TV is mounted on the wall. The kitchenette area is equipped with a mini-fridge and basic amenities.
Farm stay in Pickens
4.97 out of 5 average rating, 250 reviews

Alinea Farm

Alinea Farm is a working family farm. We are a 10-acre homestead full of farm animals and gardens. The airbnb is newly remodeled and situated above our detached garage. While our family home is not far, we have created a private space and are very mindful to provide quiet, peace, and privacy for our guests. We are hosts at heart and are here to accommodate whatever you need from your stay, whether to be left in peace to a lively tour around the farm. We hope you will find rest here.

Top guest favorite
A newly constructed duplex is depicted, featuring a light grey exterior with black shutters. The entrance is framed by two elegant chairs on the porch. A spacious driveway leads to a well-maintained area, surrounded by neat landscaping and a clear blue sky.
Home in Pickens
4.96 out of 5 average rating, 152 reviews

Cottage in Pickens

Enjoy easy access to all the Upstate has to offer! This newly constructed 2 bedroom, 1 bath duplex apartment is located along the Doodle Trail bike route. Enjoy hiking trails and waterfalls at Table Rock and Caesars Head State Parks, catch a Clemson football game, or check out Falls Park and downtown Greenville, all from one convenient location! The home is across the street from a well-maintained local park and playground and within walking distance to a coffee shop and restaurants.

Top guest favorite
A well-equipped camper kitchen features essential appliances, including a stove and a refrigerator, alongside a spacious countertop. A comfortable reclining sofa sits invitingly, complemented by natural light from the windows that provide a view of the surrounding greenery. A soft area rug adds warmth to the space.
Camper/RV in Salem
4.93 out of 5 average rating, 188 reviews

Camp Glamp at Jocassee

Half a mile from Lake Jocassee is a peaceful hideaway on a private drive. Wake up to birds singing; fall asleep to the sound of crickets and katydids. Enjoy quiet and solitude on a small private deck, then hit the country's most beautiful lake to learn why National Geographic calls the Jocassee Gorges one of "50 of the world's last great places". Waterfalls, wildlife, and the wonder and mystery of Lake Jocassee await you! Then come back to a clean and comfortable 'glamping' experience.

Guest favorite
A custom-built cabin is surrounded by trees, showcasing a wooden exterior with a metal roof. A small deck leads to the entrance, and a stone path is visible in front. Natural light reflects off the wooden surfaces, enhancing the cabin's rustic charm.
Cabin in Pickens
4.95 out of 5 average rating, 172 reviews

Peace-In-The-Forest Retreat

PEACE-IN-THE-FOREST RETREAT offers a reprieve by providing privacy & quiet in a beautiful, custom-built cabin, on 100 forested acres w/ miles of hiking trails. REGARDING COVID-19, we provide a healthy place to be, breathe & move & WE ARE GOING THE EXTRA MILE to ensure that all touchable surfaces in our cabin are sanitized. We are 20-40 minutes from 6 SC State Parks+Dupont Forest, State Heritage Preserves; Lakes Keowee, Jocassee & Hartwell; Foothills trail &more!

Popular amenities for Pickens County vacation rentals