Townhome vacation rentals in Pickens County

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Top-rated townhouse rentals in Pickens County

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Top guest favorite
The image showcases a scenic lake view with boats docked during sunset, complemented by vibrant orange hues in the sky. Tennis and pickleball courts are depicted in one section, while another highlights a spacious saltwater pool, inviting relaxation amidst the surrounding trees.
Townhouse in Salem
4.96 out of 5 average rating, 47 reviews

Amenitiy Rich Resort Access - Get Away Memories!

Escape to the lake and cool mountains. The gated resort of Keowee Key has tons of amenities, including water rentals (boats, paddleboards, kayaks); 3 pools; lighted tennis/pickleball; fine & casual dining, large fitness center; golf course, and walking & hiking trails just outside your door. This peaceful home has 3 levels, 2 sunrooms, 2 living rooms and enlarged kitchen. Perfect family getaway to build memories or relax. 25 minutes from Clemson and day trip to Highlands, Cashiers or Greenville

Top guest favorite
A spacious bedroom features a four-poster bed adorned with plush pillows and a neatly placed towel. Soft lighting creates a calming atmosphere, while a piece of artwork hangs above the bed. Ample closet space is visible through white louvered doors.
Townhouse in Salem
5 out of 5 average rating, 76 reviews

Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom

Escape to this spacious three-story, family-friendly home w bedrooms, baths, and decks on each level—perfect for large families (sleeps 9). Pack ’n Play available, easy front-door parking, & access to resort pools, spa, and sauna included. It's a professionally cleaned, dog-friendly 3BR, 3BA townhome w loft/3 living spaces. Enjoy wooded rolling hills w wildlife, resort amenities (some activities like golf or boat rentals have fees), ping-pong, board games, and a deck fireplace under the stars.

Guest favorite
The exterior of the townhouse features a neutral brown wood paneling along with a brick chimney. A welcoming front porch with white railings leads up to the front door. The surrounding area includes neatly trimmed bushes and a backdrop of greenery, indicating a peaceful community setting.
Townhouse in Clemson
4.93 out of 5 average rating, 14 reviews

Rosehill Villa at Clemson Botanical Gardens

Newly renovated 4 bedroom 3.5 bathroom townhouse. Open concept kitchen, living room and dining room. Small deck located off the kitchen and dining room to relax with coffee. Bring the whole family to this great place with lots of room for fun. Clemson Botanical gardens are a 10 minute walk down a foot path and continue on for another 25 minutes to reach Memorial Stadium (football), Littlejohn Coliseum (basketball), Doug Kingsmore Stadium (baseball), and Brooks Theater where the Tigers play.

Guest favorite
A two-story home is surrounded by lush greenery and tall trees. Its exterior features orange window shutters and a welcoming driveway that curves towards the garage. The yard is well-maintained, providing a peaceful setting.
Townhouse in Seneca
5 out of 5 average rating, 16 reviews

Charming Seneca Home - 3 Mi to Memorial Stadium!

Experience the best of Seneca, SC, in this spacious 4-bedroom, 2-bathroom vacation rental! With its prime location near top attractions like Lake Keowee and Clemson University, this townhome is perfect for adventurers and sports fans alike. Enjoy fun-filled days on the water at Lake Keowee or cheer on the Tigers at Memorial Stadium! When you’re not exploring the area, relax in the comfortable interior of this townhome, designed to provide a welcoming home away from home for your vacation.

Guest favorite
Townhouse in Easley
4.94 out of 5 average rating, 17 reviews

Gorgeous Clemson | Greenville Retreat 2BR 2.5 Bath

Enjoy this stylish urban Loft offering with modern comfort and amenties. - Just 18 miles from Clemson and 13 miles from downtown Greenville. Full Kitchen - 2 comfy bedrooms - 2.5 baths - Private balcony - Just 5 Minute walk to Silos food hall and doodle trail. - Just a 10 Minute walk to downtown shopping and restaurants - Free Private Parking! The Braw is the perfect location for game weekends & family visits w/ college kids, business travel! Book your stay before the calendar fills!

Guest favorite
A two-story townhouse is depicted, featuring a combination of beige siding and dark trim. Large windows allow ample natural light, and a red door adds a pop of color. The surrounding landscape includes a small lawn with trees, showcasing autumn foliage.
Townhouse in Clemson
5 out of 5 average rating, 6 reviews

Brand New Build Clemson Retreat 3br/3bath sleeps 8

This is a brand new build, two story townhouse. Comfortably sleeps 8. All new furnishings. Kitchen has all that you need to host a football weekend, graduation party or special dinner. All 3 bedrooms have en-suite full bathrooms. Sleeper sofa has Queen gel foam mattress. Kitchen fully stocked. Walking distance to Clemson, and Botanical Gardens. Short drive to restaurants in Patrick Square downtown Clemson and Pendelton. Three parking spaces assigned to house. Truly great location!

Guest favorite
A large outdoor swimming pool is set against a scenic lakeside backdrop, surrounded by lounge chairs. The water glimmers in sunlight, with trees lining the perimeter. Nearby, a marina with docked boats and a parking area is visible.
Townhouse in Salem
5 out of 5 average rating, 12 reviews

Walk to Lake Keowee: Salem Townhome w/ Deck

Walk to Private Beach | Fireplace | Newly Renovated | 10 Mi to Clemson Escape to this 4-bedroom, 3-bath vacation rental in Salem! Perfect for families, this townhome offers ample space to unwind after exploring Lake Keowee or Table Rock State Park. With a full kitchen and access to community amenities, this townhome has everything you need for a memorable retreat! Be sure to relax by the community pool or play a round of golf before cozying up by the fireplace!

The exterior of a two-story townhouse is showcased, featuring blue-gray siding and contrasting black shutters. A bright yellow front door is positioned above a small mat, while a two-car garage with white doors is seen on the right. Landscaping includes dark mulch and small plants.
Townhouse in Easley
5 out of 5 average rating, 3 reviews

Exclusive Luxury Escape

Welcome to this cozy place in Easley, SC—perfectly located between Clemson and Greenville! Just 20 minutes from Clemson University and downtown Greenville, this space is ideal for college visits, game days, or exploring the Upstate. Enjoy a quiet, comfortable stay with modern amenities and easy access to local dining, shopping, and outdoor activities. Whether you're here for a Tigers game or a weekend getaway, our home offers the perfect base for your adventure.

Guest favorite
Townhouse in Seneca
5 out of 5 average rating, 8 reviews

Boat Dock: Lake-View Retreat 5 Mi to Dtwn Clemson

Whether you're here for a relaxing lakefront getaway or to cheer on the Tigers, this impressive Seneca house is the perfect choice for you! Ideally situated on a private lot of nearly one acre on picturesque Lake Hartwell, this vacation rental boasts ample deck space, three screened porches, and a media room perfect for watching the big game. You'll love being within four miles of Clemson University, museums, parks, shops, restaurants, and more!

An overhead view of a cozy living room reveals a dark sofa and two patterned armchairs situated around a coffee table. A colorful area rug covers the hardwood floor. Natural light filters in through large windows with sheer curtains, and a television is positioned to one side next to a fireplace.
Townhouse in Salem
4.83 out of 5 average rating, 30 reviews

Keowee Key Townhome with Amenities - Pet Friendly

We are a pet friendly townhome so your puppy baby can vacation with you as well. This pristine community nestled in the foothills of the Blue Ridge Mountains surrounded by Lake Keowee features 2 marinas (plus kayaking or canoeing), 2 outdoor pools, and indoor Olympic size pool plus fitness center, on-site restaurant and the Bistro cafe. Feel free to go leisure walking on the trails throughout the compound which is all easily accessible.

Top guest favorite
Townhouse in Clemson
4.98 out of 5 average rating, 40 reviews

TigerTown HideAway

Perfect spot for your visit to Clemson. 4 bedroom/4.5 bathroom close to everything. Property backs up to Clemson’s Botanical Gardens. Beautiful Lake Keowee and Hartwell is a short drive away. Lake Jocasse is about an hours drive. 2 minute drive to downtown. Near restaurants and grocery stores. This townhome can sleep 10+ Anderson - 15 min Greenville -45 min

Guest favorite
The townhouse exterior is displayed, featuring warm brown brick with blue shutters framing the windows. A vibrant orange door provides a welcoming entry, while a small tree adds greenery to the front yard. A potted plant is positioned near the entrance.
Townhouse in Clemson
4.91 out of 5 average rating, 23 reviews

Townhouse within walking distance of the stadium!

Pack your bags for a conveniently located home away from home for the next Clemson event! You are located within walking distance of downtown Clemson and the University! This is a 2 bedroom 1.5 bathroom townhouse with parking and a private backyard!

Popular amenities for Pickens County townhouse rentals