Townhome vacation rentals in Pickens County

4.96 out of 5 average rating, 53 reviews

Amenity Rich Keowee Resort - 25 min to Clemson

Enjoy the Best of Both Worlds in our spacious 4-bedroom, 3-bath townhome in the gated Keowee Key Resort. Where lake life, mountain views, and resort amenities come together for the perfect getaway. Spread over three levels with two living rooms and two sunrooms, the home offers plenty of space for families, couples, or friends traveling together. When you're visiting Lake Keowee, Clemson University, or the Blue Ridge Mountains, this home is a comfortable base for both adventure and relaxation.

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Top guest favorite

The entrance of a modern resort building is framed by a striking architectural design featuring a large overhanging roof and stone accents. Steps lead up to the glass doors, while landscaped greenery complements the exterior.

5.0 out of 5 average rating, 80 reviews

Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom

Escape to this spacious three-story, family-friendly home w bedrooms, baths, and decks on each level—perfect for large families (sleeps 9). Pack ’n Play available, easy front-door parking, & access to resort pools, spa, and sauna included. It's a professionally cleaned, dog-friendly 3BR, 3BA townhome w loft/3 living spaces. Enjoy wooded rolling hills w wildlife, resort amenities (some activities like golf or boat rentals have fees), ping-pong, board games, and a deck fireplace under the stars.

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4.93 out of 5 average rating, 29 reviews

Townhouse in Easley

Modern 2BR 2.5 Bath Loft Near Clemson & Greenville

Your Perfect Home Base for Easley, Clemson & Greenville Adventures An ideal retreat The Bonnie, thoughtfully designed modern townhome just minutes from Clemson, downtown Greenville, charming Easley. Whether you're visiting college game days, exploring vibrant food/ arts scene, or seeking a comfortable base for business travel, this 3 story home welcomes you w/ style, substance, genuine hospitality. fast WiFi, premium bedding, chef's kitchen, private balcony, you'll feel right at home.

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5.0 out of 5 average rating, 18 reviews

A two-story home is surrounded by lush greenery and tall trees. Its exterior features orange window shutters and a welcoming driveway that curves towards the garage. The yard is well-maintained, providing a peaceful setting.

Townhouse in Seneca

Clemson Weekends 3 Mi From Memorial Stadium

5-Vehicle Driveway | RV & Trailer Parking | 2 Main-Floor Bedrooms Clemson weekends come easy at this Seneca vacation rental, 3 miles from Memorial Stadium and ready for the October 17 Charleston Southern matchup. Rally your crew over breakfast in the full kitchen, then return after the final whistle to spread out across roomy living spaces and replay every highlight while 5-vehicle parking keeps game-day logistics simple. Turn your next Tiger kickoff into a full weekend in Seneca.

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A two-story townhouse is depicted, featuring a combination of beige siding and dark trim. Large windows allow ample natural light, and a red door adds a pop of color. The surrounding landscape includes a small lawn with trees, showcasing autumn foliage.

5.0 out of 5 average rating, 8 reviews

Brand New Build Clemson Retreat 3br/3bath sleeps 8

This is a new build, two story townhouse. Comfortably sleeps 8. All new furnishings. Kitchen has all that you need to host a football weekend, graduation party or special dinner. All 3 bedrooms have en-suite full bathrooms. Sleeper sofa has Queen gel foam mattress. Kitchen fully stocked. Walking distance to Clemson, and Botanical Gardens. Short drive to restaurants in Patrick Square downtown Clemson and Pendelton. Two parking spaces assigned to house. Truly great location!

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A spacious living area is furnished with comfortable gray sofas and a round coffee table, creating an inviting space. Natural light filters through large windows, illuminating a dining area with wooden chairs. A serene landscape photograph decorates the wall, enhancing the room’s calming ambiance.

4.71 out of 5 average rating, 14 reviews

Fun Lake Keowee TownHse Golf Tennis Picklball Pool

A lush serene setting of trees, walking paths and nature surround this 3 level townhome within the gates of Keowee Key. You will have quick access to Lake Keowee (2 marinas with kayak and boat launch and boat rentals) Pickle Ball and Tennis courts at the Fitness Center (some additional fees may apply), nearby golf and indoor and outdoor pools. This home is available as a dedicated rental property. The owners do not keep any of their personal items in the home.

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A large outdoor swimming pool is set against a scenic lakeside backdrop, surrounded by lounge chairs. The water glimmers in sunlight, with trees lining the perimeter. Nearby, a marina with docked boats and a parking area is visible.

5.0 out of 5 average rating, 13 reviews

Walk to Lake Keowee: Salem Townhome w/ Deck

Walk to Private Beach | Fireplace | Newly Renovated | 10 Mi to Clemson Escape to this 4-bedroom, 3-bath vacation rental in Salem! Perfect for families, this townhome offers ample space to unwind after exploring Lake Keowee or Table Rock State Park. With a full kitchen and access to community amenities, this townhome has everything you need for a memorable retreat! Be sure to relax by the community pool or play a round of golf before cozying up by the fireplace!

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The exterior of a two-story townhouse is showcased, featuring blue-gray siding and contrasting black shutters. A bright yellow front door is positioned above a small mat, while a two-car garage with white doors is seen on the right. Landscaping includes dark mulch and small plants.

Townhouse in Easley

Exclusive Luxury Escape

Welcome to this cozy place in Easley, SC—perfectly located between Clemson and Greenville! Just 20 minutes from Clemson University and downtown Greenville, this space is ideal for college visits, game days, or exploring the Upstate. Enjoy a quiet, comfortable stay with modern amenities and easy access to local dining, shopping, and outdoor activities. Whether you're here for a Tigers game or a weekend getaway, our home offers the perfect base for your adventure.

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5.0 out of 5 average rating, 3 reviews

5.0 out of 5 average rating, 8 reviews

Townhouse in Seneca

Boat Dock: Lake-View Retreat 5 Mi to Dtwn Clemson

Whether you're here for a relaxing lakefront getaway or to cheer on the Tigers, this impressive Seneca house is the perfect choice for you! Ideally situated on a private lot of nearly one acre on picturesque Lake Hartwell, this vacation rental boasts ample deck space, three screened porches, and a media room perfect for watching the big game. You'll love being within four miles of Clemson University, museums, parks, shops, restaurants, and more!

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Superhost

5.0 out of 5 average rating, 3 reviews

Rosehill Villa two at Clemson Botanical Gardens

Newly renovated 4 bedroom 2.5 bathroom townhouse. Open concept kitchen, living room and dining room. Small deck located off the livingroom to relax with coffee. Bring the whole family to this great place with lots of room for fun. This property backs up to the Clemson Botanical Gardens and is a 5 minute drive to reach Memorial Stadium (football), Littlejohn Coliseum (basketball), all where the Tigers play.

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The brick townhouse exterior features well-maintained shrubs and a neatly manicured lawn. Each unit has a front porch with steps leading to the dark doors, framed by window shutters. The overall design reflects a classic charm within a welcoming neighborhood.

5.0 out of 5 average rating, 9 reviews

Royal Tiger - Walk to Death Valley!

Charming & Updated Townhouse - Walk to Clemson's Death Valley! Immerse yourself in the vibrant spirit of Clemson from this beautifully updated townhouse, ideally situated within walking distance to the legendary Death Valley Stadium, home of the Clemson Tigers. Perfectly designed for game day excitement and cozy evenings, this home offers the perfect blend of comfort, convenience, and style.

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Top guest favorite