
Townhome vacation rentals in Pickens County
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Top-rated townhouse rentals in Pickens County
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Amenitiy Rich Resort Access - Get Away Memories!
Escape to the lake and cool mountains. The gated resort of Keowee Key has tons of amenities, including water rentals (boats, paddleboards, kayaks); 3 pools; lighted tennis/pickleball; fine & casual dining, large fitness center; golf course, and walking & hiking trails just outside your door. This peaceful home has 3 levels, 2 sunrooms, 2 living rooms and enlarged kitchen. Perfect family getaway to build memories or relax. 25 minutes from Clemson and day trip to Highlands, Cashiers or Greenville

Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom
Escape to this spacious three-story, family-friendly home w bedrooms, baths, and decks on each level—perfect for large families (sleeps 9). Pack ’n Play available, easy front-door parking, & access to resort pools, spa, and sauna included. It's a professionally cleaned, dog-friendly 3BR, 3BA townhome w loft/3 living spaces. Enjoy wooded rolling hills w wildlife, resort amenities (some activities like golf or boat rentals have fees), ping-pong, board games, and a deck fireplace under the stars.

Rosehill Villa at Clemson Botanical Gardens
Newly renovated 4 bedroom 3.5 bathroom townhouse. Open concept kitchen, living room and dining room. Small deck located off the kitchen and dining room to relax with coffee. Bring the whole family to this great place with lots of room for fun. Clemson Botanical gardens are a 10 minute walk down a foot path and continue on for another 25 minutes to reach Memorial Stadium (football), Littlejohn Coliseum (basketball), Doug Kingsmore Stadium (baseball), and Brooks Theater where the Tigers play.

Charming Seneca Home - 3 Mi to Memorial Stadium!
Experience the best of Seneca, SC, in this spacious 4-bedroom, 2-bathroom vacation rental! With its prime location near top attractions like Lake Keowee and Clemson University, this townhome is perfect for adventurers and sports fans alike. Enjoy fun-filled days on the water at Lake Keowee or cheer on the Tigers at Memorial Stadium! When you’re not exploring the area, relax in the comfortable interior of this townhome, designed to provide a welcoming home away from home for your vacation.

Gorgeous Clemson | Greenville Retreat 2BR 2.5 Bath
Enjoy this stylish urban Loft offering with modern comfort and amenties. - Just 18 miles from Clemson and 13 miles from downtown Greenville. Full Kitchen - 2 comfy bedrooms - 2.5 baths - Private balcony - Just 5 Minute walk to Silos food hall and doodle trail. - Just a 10 Minute walk to downtown shopping and restaurants - Free Private Parking! The Braw is the perfect location for game weekends & family visits w/ college kids, business travel! Book your stay before the calendar fills!

Brand New Build Clemson Retreat 3br/3bath sleeps 8
This is a brand new build, two story townhouse. Comfortably sleeps 8. All new furnishings. Kitchen has all that you need to host a football weekend, graduation party or special dinner. All 3 bedrooms have en-suite full bathrooms. Sleeper sofa has Queen gel foam mattress. Kitchen fully stocked. Walking distance to Clemson, and Botanical Gardens. Short drive to restaurants in Patrick Square downtown Clemson and Pendelton. Three parking spaces assigned to house. Truly great location!

Walk to Lake Keowee: Salem Townhome w/ Deck
Walk to Private Beach | Fireplace | Newly Renovated | 10 Mi to Clemson Escape to this 4-bedroom, 3-bath vacation rental in Salem! Perfect for families, this townhome offers ample space to unwind after exploring Lake Keowee or Table Rock State Park. With a full kitchen and access to community amenities, this townhome has everything you need for a memorable retreat! Be sure to relax by the community pool or play a round of golf before cozying up by the fireplace!

Exclusive Luxury Escape
Welcome to this cozy place in Easley, SC—perfectly located between Clemson and Greenville! Just 20 minutes from Clemson University and downtown Greenville, this space is ideal for college visits, game days, or exploring the Upstate. Enjoy a quiet, comfortable stay with modern amenities and easy access to local dining, shopping, and outdoor activities. Whether you're here for a Tigers game or a weekend getaway, our home offers the perfect base for your adventure.

Boat Dock: Lake-View Retreat 5 Mi to Dtwn Clemson
Whether you're here for a relaxing lakefront getaway or to cheer on the Tigers, this impressive Seneca house is the perfect choice for you! Ideally situated on a private lot of nearly one acre on picturesque Lake Hartwell, this vacation rental boasts ample deck space, three screened porches, and a media room perfect for watching the big game. You'll love being within four miles of Clemson University, museums, parks, shops, restaurants, and more!

Keowee Key Townhome with Amenities - Pet Friendly
We are a pet friendly townhome so your puppy baby can vacation with you as well. This pristine community nestled in the foothills of the Blue Ridge Mountains surrounded by Lake Keowee features 2 marinas (plus kayaking or canoeing), 2 outdoor pools, and indoor Olympic size pool plus fitness center, on-site restaurant and the Bistro cafe. Feel free to go leisure walking on the trails throughout the compound which is all easily accessible.

TigerTown HideAway
Perfect spot for your visit to Clemson. 4 bedroom/4.5 bathroom close to everything. Property backs up to Clemson’s Botanical Gardens. Beautiful Lake Keowee and Hartwell is a short drive away. Lake Jocasse is about an hours drive. 2 minute drive to downtown. Near restaurants and grocery stores. This townhome can sleep 10+ Anderson - 15 min Greenville -45 min

Townhouse within walking distance of the stadium!
Pack your bags for a conveniently located home away from home for the next Clemson event! You are located within walking distance of downtown Clemson and the University! This is a 2 bedroom 1.5 bathroom townhouse with parking and a private backyard!
Popular amenities for Pickens County townhouse rentals
Family-friendly townhouse rentals

Tiger Nest in Clemson, SC!

2BR 2.5 Downtown Oasis Full Kitchen | Pet Friendly

Royal Tiger - Walk to Death Valley!

Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom

TigerTown HideAway

Slice of Heaven at the Clemson Dike

Retreat at Rose Hill, close to Clemson University!

2BR 2.5BA Luxury Retreat Full Kitchen Luxury Bath
Townhouse rentals with a washer and dryer

Tall Ship 331 Waterfront 2BR Condo in Salem, SC

Tiger Nest in Clemson, SC!

Salem Vacation Rental w/ Lake Keowee Access!

Private Balcony: Lake Keowee Home w/ Pool Access

Lake Keowee Gem! Close to Clemson & Hiking Trails

Royal Tiger - Walk to Death Valley!

Seneca Escape w/ Screened Patio: Near Lakes!

Tiger Town Getaway: 2 Mi to Downtown & Campus!
Townhouse rentals with a patio

The Deck House at Keowee Key Lake

Fun Lake Keowee TownHse Golf Tennis Picklball Pool

2BR 2.5 Downtown Oasis Full Kitchen | Pet Friendly

2BR 2.5BA Luxury Retreat Full Kitchen Luxury Bath

Rosehill Villa two at Clemson Botanical Gardens

Spacious Modern Loft 2BR 2.5 BA Greenville Clemson
Destinations to explore
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- House rentals Pickens County
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- Townhouse rentals South Carolina
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- Blue Ridge Parkway
- The North Carolina Arboretum
- Black Rock Mountain State Park
- River Arts District
- Gorges State Park
- Chimney Rock State Park
- Table Rock State Park
- Clemson University
- Tallulah Gorge State Park
- Lake Lure Beach and Water Park
- Tryon International Equestrian Center
- Jump Off Rock
- Harrah's Cherokee Center - Asheville
- Biltmore House
- Bon Secours Wellness Arena
- Woolworth Walk
- Saint Paul Mountain Vineyards
- French Broad River Park
- Thomas Wolfe Memorial
- Chattooga Belle Farm
- Carl Sandburg Home National Historic Site
- Burntshirt Vineyards
- The Orange Peel
- Fred W Symmes Chapel




