Pet-friendly vacation rentals in Pickens County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Pickens County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
The exterior of a charming brick house is framed by lush greenery. A stone pathway leads to the entrance, flanked by well-maintained shrubs and trees. Large windows allow natural light to fill the living spaces inside, providing a welcoming exterior view.
Home in Pickens
4.96 out of 5 average rating, 109 reviews

Welcome to Downtown Pickens

This beautiful brick home located on a spacious lot is waiting for you! Your family will be close to everything when you stay at this centrally-located place. 3 spacious bedrooms and 1.5 baths will make life a breeze. Dine or relax on the covered patio while the kids play in the gently sloping private backyard. Your stay on West Main St will be a dream with all the amenities of downtown Pickens being in walking distance. You are also only 20 minutes from all Greenville or Clemson has to offer.

Top guest favorite
A modern one-story ranch house is depicted in a tranquil setting, featuring a spacious driveway and manicured landscaping. Natural light illuminates the exterior, enhanced by a welcoming entryway with decorative planters and a covered porch, surrounded by lush greenery and large trees.
Home in Travelers Rest
5 out of 5 average rating, 142 reviews

Modern Wooded Retreat

Come enjoy this modern, 1.6 acre retreat! Relax with the whole family in a place you'll never want to leave. Located 5 min. to downtown TR and less than 20 min to downtown Greenville! Roast marshmallows by the firepit, play yard jenga, connect 4 and cornhole in the fully fenced, dog friendly back yard. Close to the swamp rabbit trail, and centrally located to lakes, hiking, fishing and exciting nightlife. Let us host you, while you explore everything Greenville and Travelers Rest have to offer.

Guest favorite
A serene outdoor scene is captured, featuring a cascading waterfall flowing into a calm creek. The surrounding area is lush with greenery, while a wooden deck is visible, complete with a chiminea. A blue chair rests near the water's edge, adding a touch of color.
Apartment in Brevard
4.98 out of 5 average rating, 368 reviews

Private Backyard Waterfall Apt | No Shared Spaces

Our charming apartment is nestled in the woods with a prime view of your own private 15 ft waterfall in the backyard. Enjoy peace & tranquility while reading a book on the hammock or warm up by the chiminea while watching the fireflies scatter about the woods. The creek is approximately 3 ft deep at the bottom of the waterfall. The property is surrounded by State Forest. If the apartment gets rented, the rest of the house is blocked from being rented. You will not be sharing ANY space.

Guest favorite
A cozy living area features a stone fireplace flanked by windows, allowing natural light to illuminate the space. A comfortable sofa is arranged around a small table, accompanied by a chair. A TV is mounted above the fireplace for entertainment.
Condo in Salem
4.97 out of 5 average rating, 144 reviews

Beautiful Lake Keowee Condo with great Amenities

"Boasting lake views, a fully equipped kitchen, and resort-style amenities, this 2-bedroom, 2-bath Salem vacation rental condo in Keowee Key will have you experiencing the true meaning of life on the lake. Cool off with a dip in the community's outdoor pool which sits right next to the marina where you can rent a boat for a day out on the water. Tee up a round of golf on the renovated 18-hole course, walk along the trails of Oconee State Park, or catch a football game at Clemson University!"

Top guest favorite
A bright living space features a comfortable gray sectional sofa with decorative pillows. A small wooden table sits beside it. A sleek chair with wooden legs offers additional seating, while a flat-screen TV is mounted on the wall. The kitchenette area is equipped with a mini-fridge and basic amenities.
Farm stay in Pickens
4.97 out of 5 average rating, 242 reviews

Alinea Farm

Alinea Farm is a working family farm. We are a 10-acre homestead full of farm animals and gardens. The airbnb is newly remodeled and situated above our detached garage. While our family home is not far, we have created a private space and are very mindful to provide quiet, peace, and privacy for our guests. We are hosts at heart and are here to accommodate whatever you need from your stay, whether to be left in peace to a lively tour around the farm. We hope you will find rest here.

Guest favorite
A lush green lawn extends across the image, framed by trees and a backdrop of rolling hills. A bright blue sky dotted with fluffy white clouds adds to the serene atmosphere. The spacious landscape offers a tranquil view of the surrounding nature.
Home in Liberty
4.93 out of 5 average rating, 123 reviews

3 Bed Home Overlooking Fishing Pond on 10 Acres

This Home is a retreat in of itself! All New Accommodations offer Large eat in Kitchen, Primary Suite with Primary Bath. Stocked Fishing Pond! Peaceful and relaxing property to enjoy privately. If you are a foodie or shopper Greenville is only 15 miles away. Greenville has landed on countless "best of" lists so it's a must see! If Clemson is what you love we are twenty minutes from campus! Business class wifi too and cable TV Enjoy Great hiking at one of the close state parks too

Guest favorite
A deck area overlooking the river features wooden railings with metal accents. Several outdoor chairs are positioned on the deck, while the river flows gently beside it. Lush trees line the riverbank, providing a natural backdrop.
Tiny home in Easley
4.9 out of 5 average rating, 244 reviews

New! Riverfront Tiny Home - Downtown Greenville SC

The River House is a boutique tiny home on the river front of the Saluda with breathtaking views - just 5 minutes from Downtown Greenville! This is a perfect place to relax, unwind, and rejuvenate. Great for a romantic couples getaway, family vacation, or friends getting together to have fun. So cozy and picturesque. You will never want to leave! Located on-site at Saluda Outdoor Center with river tubing tours, 13 Stripes Brewery/Restaurant, live music, fishing and more (within season).

Superhost
A sturdy wooden staircase leads up to a private entrance, framed by an attractive wooden exterior. Softly glowing string lights outline the steps, enhancing the welcoming ambiance. A small seating area is visible at the top, surrounded by lush greenery and flower beds.
Guest suite in Greenville
4.88 out of 5 average rating, 375 reviews

Lakefront modern private guest suite 6mi to DT

MINI PRIVATE OASIS. 6 MILES TO DOWNTOWN GREENVILLE! LAKEFRONT + PRIVATE DOCK NY Times #1 AMERICAN CITY! Experience modern luxury in your serene mini suite. Please note: the suite is located as an extension attached to a classical Scandinavian chalet. The suite is private. No shared spaces, shared soundproofed wall. 6mi downtown Greenville Amenities include: - Private entrance & patio - Private dock - 43” Roku TV - Charcoal grill, fire pit - Luxury toiletries - Blackout curtains

Top guest favorite
A two-story cottage is nestled among trees, featuring a combination of white and brown siding. A wooden deck extends from the front, providing access to the entrance. Large windows allow for natural light, while surrounding greenery adds to the serene ambiance.
Cottage in Greenville
4.85 out of 5 average rating, 244 reviews

Acorn Cottage at Saluda River Farms

We call this the adventure cottage — perfect for travelers seeking a truly eclectic and cozy retreat. Acorn Cottage is a tiny, peaceful hideaway ideal for a quiet weekend escape. This 220 sq ft space offers a step up from glamping, featuring a comfortable bed (note: you’ll need to step up to get in), a cozy living area, a kitchenette, and a full bathroom. Outside, a charming deck invites you to relax and soak in the surroundings. Just the right size for your next weekend getaway!

Guest favorite
A custom-built cabin is surrounded by trees, showcasing a wooden exterior with a metal roof. A small deck leads to the entrance, and a stone path is visible in front. Natural light reflects off the wooden surfaces, enhancing the cabin's rustic charm.
Cabin in Pickens
4.95 out of 5 average rating, 170 reviews

Peace-In-The-Forest Retreat

PEACE-IN-THE-FOREST RETREAT offers a reprieve by providing privacy & quiet in a beautiful, custom-built cabin, on 100 forested acres w/ miles of hiking trails. REGARDING COVID-19, we provide a healthy place to be, breathe & move & WE ARE GOING THE EXTRA MILE to ensure that all touchable surfaces in our cabin are sanitized. We are 20-40 minutes from 6 SC State Parks+Dupont Forest, State Heritage Preserves; Lakes Keowee, Jocassee & Hartwell; Foothills trail &more!

Top guest favorite
A unique dome-shaped structure is surrounded by greenery, showcasing a small window and a pathway leading to it. An outdoor wooden picnic table and swing are visible under a pergola, creating a welcoming space for outdoor gatherings.
Dome in Slater-Marietta
4.97 out of 5 average rating, 324 reviews

Hobbit Hideaway- Do Something Different!

Trek back from Mordor and retire to a full kitchen, AC/heat, queen bed, pullout couch w/ new memory foam pad, washer/dryer, shower and more. Enjoy the patio where you can be the lord of the fire ring, grill PO-TAY-TOES, enjoy the swing, hammock, horseshoes, axe throwing, games and more. Located 12 min from beautiful Traveler’s Rest, where you can run/bike your little hobbit heart out on the 22-mile Swamp Rabbit trail. Also 30 min from downtown Greenville.

Top guest favorite
A view capturing the entryway leading to a cozy bedroom space. The warm wooden accent wall complements the inviting bedding. A small side table holds a decorative item, while light fills the room through a ceiling fixture, creating a serene atmosphere.
Camper/RV in Pendleton
4.95 out of 5 average rating, 103 reviews

The Pendle-Tin

At the Pendle-tin, you’re close to it all, yet feel tucked away in the west end of downtown Pendleton. You’re 5-8 min from Clemson’s Death Valley, and 2 blocks from downtown Pendleton where you’ll find eateries, and shops. About 5 min from the lake and about 45-50 min from the mountains. Inside you’re Equipped with a kitchen, full bath, WiFi, smart tv , queen bed and separate work space . Outside you have seating for 4 and a propane fire pit.

Popular amenities for Pickens County pet-friendly home rentals