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Pet-friendly vacation rentals in Pickens County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Pickens County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
An open living space features a large wooden bar countertop with three metal stools. A cozy seating area is arranged around a stone fireplace, complemented by a television mounted on the wall. Light streams in from the adjacent room, highlighting the rustic charm.
Home in Greenville
4.9 out of 5 average rating, 154 reviews

Fisher's Paradise on Lake Saluda w Boat Ramp

Stay at Saluda Lake Landing in this unique lakefront property getaway that has a house, cafe, boat ramp, and dock. Perfect for fishing, kayaking, paddle boarding and more. Once home, relax and cook the days catch indoors and out. This property is partially public as we do get other customers for the cafe, dock, and boat ramp. Please be aware that our employees will be around the property during normal working hours. If you are planning to bring your furry friend with you please reach out prior.

Guest favorite
The exterior of a charming brick house is framed by lush greenery. A stone pathway leads to the entrance, flanked by well-maintained shrubs and trees. Large windows allow natural light to fill the living spaces inside, providing a welcoming exterior view.
Home in Pickens
4.96 out of 5 average rating, 125 reviews

Welcome to Downtown Pickens

This beautiful brick home located on a spacious lot is waiting for you! Your family will be close to everything when you stay at this centrally-located place. 3 spacious bedrooms and 1.5 baths will make life a breeze. Dine or relax on the covered patio while the kids play in the gently sloping private backyard. Your stay on West Main St will be a dream with all the amenities of downtown Pickens being in walking distance. You are also only 20 minutes from all Greenville or Clemson has to offer.

Guest favorite
A serene outdoor scene is captured, featuring a cascading waterfall flowing into a calm creek. The surrounding area is lush with greenery, while a wooden deck is visible, complete with a chiminea. A blue chair rests near the water's edge, adding a touch of color.
Apartment in Brevard
4.98 out of 5 average rating, 395 reviews

Private Waterfall Apt | No Shared Spaces | pets+

Our charming apartment is nestled in the woods with a prime view of your own private 15 ft waterfall in the backyard. Enjoy peace & tranquility while reading a book on the hammock or warm up by the chiminea while watching the fireflies scatter about the woods. The creek is approximately 3 ft deep at the bottom of the waterfall. The property is surrounded by State Forest. If the apartment gets rented, the rest of the house is blocked from being rented. You will not be sharing ANY space.

Top guest favorite
A studio apartment is seen from a corner, featuring a kitchen with orange cabinetry and stainless steel appliances. Two armchairs and a small dining table are positioned in the living area, with a television mounted on the wall. Ample lighting and a neutral color palette are present.
Home in Pendleton
4.88 out of 5 average rating, 130 reviews

Basement apartment in Pendleton w/ sep. entrance

This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Guest favorite
A charming cabin is nestled among towering trees, with a sloped metal roof and rustic log walls. Lush greenery surrounds the property, while vibrant blue hydrangeas bloom in the foreground. A fire pit with seating is positioned to the right, creating an inviting outdoor space.
Guesthouse in Sunset
4.91 out of 5 average rating, 440 reviews

Mountain Cabin on Creek at Jocassee Gorge.

Welcome to Laurel Valley. A tiny, sleepy neighborhood at the top of a mountain, hidden from the hustle of civilization. This adorable cabin is nestled in beautiful Jocassee Gorge. Minutes away from multiple attractions including Sassafras Mountain and Twin Falls. Property borders thousands of acres of protected land with 5 star trails . This mountain cabin is in a unique setting that time forgot. The rushing creek outside helps you to peel off the world and get a great night's sleep.

Top guest favorite
A serene bedroom features a four-poster bed draped with soft textiles, complemented by cozy fur accent pieces. Warm lighting creates a relaxing ambiance, while decorative wall frames and patterned rugs enhance the inviting atmosphere. Multiple windows allow natural light to filter in.
Home in Easley
4.99 out of 5 average rating, 133 reviews

Comfy, cozy duplex apt in old home downtown Easley

Comfortable, CLEAN, safe, serene, remodeled duplex apartment w/private entrance thru back of home - 20 mins to Gville/Clemson. Stocked for cooking. Near hiking, climbing, kayaking, diving, fishing, restaurants, breweries, pubs, theatres, museums, hospitals, live music venues, shopping, universities, and churches. Come home to comfy robes and rooms designed for relaxation. Note: Easley has a train track downtown - a few blocks away. This is important to note. Self check-in thru passcode

Top guest favorite
A bright living space features a comfortable gray sectional sofa with decorative pillows. A small wooden table sits beside it. A sleek chair with wooden legs offers additional seating, while a flat-screen TV is mounted on the wall. The kitchenette area is equipped with a mini-fridge and basic amenities.
Farm stay in Pickens
4.97 out of 5 average rating, 265 reviews

Alinea Farm

Alinea Farm is a working family farm. We are a 10-acre homestead full of farm animals and gardens. The airbnb is newly remodeled and situated above our detached garage. While our family home is not far, we have created a private space and are very mindful to provide quiet, peace, and privacy for our guests. We are hosts at heart and are here to accommodate whatever you need from your stay, whether to be left in peace to a lively tour around the farm. We hope you will find rest here.

Top guest favorite
A lush green lawn extends across the image, framed by trees and a backdrop of rolling hills. A bright blue sky dotted with fluffy white clouds adds to the serene atmosphere. The spacious landscape offers a tranquil view of the surrounding nature.
Home in Liberty
4.94 out of 5 average rating, 148 reviews

3 Bed Home Overlooking Fishing Pond on 10 Acres

This Home is a retreat in of itself! All New Accommodations offer Large eat in Kitchen, Primary Suite with Primary Bath. Stocked Fishing Pond! Peaceful and relaxing property to enjoy privately. If you are a foodie or shopper Greenville is only 15 miles away. Greenville has landed on countless "best of" lists so it's a must see! If Clemson is what you love we are twenty minutes from campus! Business class wifi too and cable TV Enjoy Great hiking at one of the close state parks too

Top guest favorite
Cabin in Pickens
4.96 out of 5 average rating, 180 reviews

Peace-In-The-Forest Retreat

PEACE-IN-THE-FOREST RETREAT offers a reprieve by providing privacy & quiet in a beautiful, custom-built cabin, on 100 forested acres w/ miles of hiking trails. REGARDING COVID-19, we provide a healthy place to be, breathe & move & WE ARE GOING THE EXTRA MILE to ensure that all touchable surfaces in our cabin are sanitized. We are 20-40 minutes from 6 SC State Parks+Dupont Forest, State Heritage Preserves; Lakes Keowee, Jocassee & Hartwell; Foothills trail &more!

Top guest favorite
A unique dome-shaped structure is surrounded by greenery, showcasing a small window and a pathway leading to it. An outdoor wooden picnic table and swing are visible under a pergola, creating a welcoming space for outdoor gatherings.
Dome in Slater-Marietta
4.98 out of 5 average rating, 365 reviews

Hobbit Hideaway- Do Something Different!

Trek back from Mordor and retire to a full kitchen, AC/heat, queen bed, pullout couch w/ new memory foam pad, washer/dryer, shower and more. Enjoy the patio where you can be the lord of the fire ring, grill PO-TAY-TOES, enjoy the swing, hammock, horseshoes, axe throwing, games and more. Located 12 min from beautiful Traveler’s Rest, where you can run/bike your little hobbit heart out on the 22-mile Swamp Rabbit trail. Also 30 min from downtown Greenville.

Top guest favorite
The exterior of a cottage features a covered porch with two rocking chairs, surrounded by well-maintained landscaping. The building has a gray exterior, dark blue shutters, and a welcoming entrance, with trees providing a natural backdrop.
Cottage in Williamston
4.96 out of 5 average rating, 146 reviews

Charming cottage on a Family Farm.

Your family will relish the convenience of this centrally located accommodation, along with spectacular views of farm animals. This charming 2-bedroom, 1-bathroom cottage is nestled on a quaint family farm, just a 5-minute drive from Interstate 85, exits 32 and 27. Conveniently positioned between Greenville and Anderson, it's also only a 20-minute drive to Clemson from the cottage. Moreover, the cottage features a fenced yard, and pets are welcome!

Top guest favorite
The exterior of the property is shown, featuring yellow siding complemented by dark shutters on the windows. A single door with glass panels is visible, providing a welcoming entrance. A grassy area is located at the base of the wall, enhancing the outdoor setting.
Guesthouse in Liberty
4.93 out of 5 average rating, 217 reviews

Holly Hideaway! 10 Highway miles to Clemson U!

Holly Hideaway is nestled between Greenville and Clemson, in the small town of Liberty. It's perfect for business travelers, couples, Clemson parents, alumni, and small families. Tiled throughout for cleanliness. Privacy, tranquility, and clean, comfortable accommodations are what we provide. We are 10 minutes from Clemson and 3 miles from SWU. The Hideaway now offers Wi-Fi and Smart TV.

Popular amenities for Pickens County pet-friendly home rentals