House vacation rentals in Pickens County

The exterior of a charming brick house is framed by lush greenery. A stone pathway leads to the entrance, flanked by well-maintained shrubs and trees. Large windows allow natural light to fill the living spaces inside, providing a welcoming exterior view.

4.96 out of 5 average rating, 101 reviews

Welcome to Downtown Pickens

This beautiful brick home located on a spacious lot is waiting for you! Your family will be close to everything when you stay at this centrally-located place. 3 spacious bedrooms and 1.5 baths will make life a breeze. Dine or relax on the covered patio while the kids play in the gently sloping private backyard. Your stay on West Main St will be a dream with all the amenities of downtown Pickens being in walking distance. You are also only 20 minutes from all Greenville or Clemson has to offer.

4.99 out of 5 average rating, 102 reviews

A serene bedroom features a four-poster bed draped with soft textiles, complemented by cozy fur accent pieces. Warm lighting creates a relaxing ambiance, while decorative wall frames and patterned rugs enhance the inviting atmosphere. Multiple windows allow natural light to filter in.

Home in Easley

Comfy, cozy duplex apt in old home downtown Easley

Comfortable, CLEAN, safe, serene, remodeled duplex apartment w/private entrance thru back of home - 20 mins to Gville/Clemson. Stocked for cooking. Near hiking, climbing, kayaking, diving, fishing, restaurants, breweries, pubs, theatres, museums, hospitals, live music venues, shopping, universities, and churches. Come home to comfy robes and rooms designed for relaxation. Note: Easley has a train track downtown - a few blocks away. This is important to note. Self check-in thru passcode

4.94 out of 5 average rating, 108 reviews

A lush green lawn extends across the image, framed by trees and a backdrop of rolling hills. A bright blue sky dotted with fluffy white clouds adds to the serene atmosphere. The spacious landscape offers a tranquil view of the surrounding nature.

Home in Liberty

3 Bed Home Overlooking Fishing Pond on 10 Acres

This Home is a retreat in of itself! All New Accommodations offer Large eat in Kitchen, Primary Suite with Primary Bath. Stocked Fishing Pond! Peaceful and relaxing property to enjoy privately. If you are a foodie or shopper Greenville is only 15 miles away. Greenville has landed on countless "best of" lists so it's a must see! If Clemson is what you love we are twenty minutes from campus! Business class wifi too and cable TV Enjoy Great hiking at one of the close state parks too

A newly constructed duplex is depicted, featuring a light grey exterior with black shutters. The entrance is framed by two elegant chairs on the porch. A spacious driveway leads to a well-maintained area, surrounded by neat landscaping and a clear blue sky.

4.95 out of 5 average rating, 132 reviews

Cottage in Pickens

Enjoy easy access to all the Upstate has to offer! This newly constructed 2 bedroom, 1 bath duplex apartment is located along the Doodle Trail bike route. Enjoy hiking trails and waterfalls at Table Rock and Caesars Head State Parks, catch a Clemson football game, or check out Falls Park and downtown Greenville, all from one convenient location! The home is across the street from a well-maintained local park and playground and within walking distance to a coffee shop and restaurants.

4.9 out of 5 average rating, 189 reviews

A single-story home is presented with a light-colored facade and a covered front porch. The driveway leads to a garage, and neatly trimmed bushes frame the entrance. Tall trees and greenery provide a natural backdrop, enhancing the property's privacy and peaceful setting.

Home in Pendleton

Comfort & Convenience Close to Campus

The perfect blend of modern charm and full comfort & convenience just minutes from Clemson, The Pendleton Square and HWY access. You will be sure to have everything you need for your visit. Comfortably sized bedrooms with queen size beds. Spacious living area with cable TV & Netflix. Bright and open kitchen and dining fully equipped for all your cooking needs. Whether you're traveling alone for a little peace & quiet, with friends, or with family... we hope you enjoy your time here!

5 out of 5 average rating, 124 reviews

A modern one-story ranch house is depicted in a tranquil setting, featuring a spacious driveway and manicured landscaping. Natural light illuminates the exterior, enhanced by a welcoming entryway with decorative planters and a covered porch, surrounded by lush greenery and large trees.

Home in Travelers Rest

Modern Wooded Retreat

Modern, 1.6 acre retreat. Relax in fun + style & seclusion! Dog friendly, fully fenced back yard! Located 5 min. To downtown TR and 20 min to downtown Greenville! Roast marshmallows by the firepit, play giant jenga and connect 4, and take in the Carolina sunset. Minutes to the swamp rabbit trail and centrally located to lakes, hiking and exciting nightlife. Let us host you, while you explore everything Greenville and Travelers Rest have to offer, with all the comforts of home.

Superhost

A spacious porch offers panoramic mountain views through large glass panels, framed by soft white curtains. The wooden floor extends outdoors, inviting relaxation amidst the surrounding greenery and distant mountain ranges.

4.96 out of 5 average rating, 186 reviews

“Mountain View Paradise” Waterfall Oasis

The peaceful sounds of a Rushing Waterfall welcome you to “Mountain Paradise”. Surrounded by 500 acres of forest and waterfalls, you have the ultimate level of privacy. Exquisitely furnished oasis with 3 bedrooms and 3 Full Baths. Enjoy 2 Master Suites with their own en suite Master Baths. Enjoy a game of golf at The Rock Golf Resort. Lake Keowee and Lake Jocassee are just minutes away. Visit Greenville, SC or head up to Brevard, NC both just 45 minutes away.

An aerial view showcases a serene landscape featuring a four-acre pond surrounded by lush greenery and autumn foliage. A winding driveway leads to a guest house nestled within the wooded area. Rolling hills provide a backdrop, enhancing the natural beauty of the property.

4.97 out of 5 average rating, 152 reviews

Our Slice of Heaven w/Views of Table Rock-Pickens

Our slice of heaven is located in the foothills of the Blue Ridge Mountains only 8 mins from Table Rock State Park. Our guest house is sitting on 55 wooded acres with our 4-acre pond and amazing awe-inspiring panoramic views of Pinnacle and Table Rock Mountain. Wrap yourself in the serenity of nature, with nothing more to wake you in the morning than the pleasant sounds of songbirds beckoning you to delight in the new day.

A cozy living area features a patterned area rug and a colorful loveseat, complemented by a comfortable chair. Light from a nearby lamp casts a warm glow. A small dining area with a wooden table is visible in the background, and a kitchenette is accessible beyond.

4.97 out of 5 average rating, 157 reviews

Hidden Retreat

4 private acres just off Hwy 11. HIKE - connector to the Palmetto trail and Table Rock State Park. BIKE - popular biking routes; Hwy 11, Hwy 288 and Hwy 178 + Doodle & Swamp Rabbit Trail. GOLF - 1 course 5 minutes away several others nearby. WATERFALLS - including the highest in the east. MOUNTAIN LAKES - 2 of the best, Jocassee & Keowee. HIDDEN RETREAT - close to many outdoor adventures. Up to 6 guests.

4.89 out of 5 average rating, 157 reviews

A living area is presented with a brown leather sofa and a white coffee table atop a textured rug. Light is provided by a ceiling fan and window, accompanied by framed artwork on the walls. A wall-mounted television is visible opposite the seating arrangement.

Home in Easley

Livin' Easley-walk to downtown-close to everything

Welcome to Livin' Easley! Your family will be close to everything when you stay at this newly renovated bungalow style house. Downtown Easley shops, restaurants, bars and The Silos are within walking distance, and Greenville and Clemson are just a short drive away. If you'd rather stay in, enjoy everything the house has to offer including bumper pool, a card table, board games, horseshoe pits, and Netflix.

4.96 out of 5 average rating, 281 reviews

A single-story guest house is set within a spacious green lawn, bordered by mature trees. The front porch features a white railing and steps leading to the entrance. The exterior is clad in light-colored siding, complemented by white shutters on the windows.

Home in Central

The Little House @ Cozy Hollow

Country living close to town. 2 miles from Cateechee Beach Park, 4 miles from SWU, 10 miles from Clemson, 12 miles from Oconee Nuclear Station, 13 miles from Garrison Arena, and 25 miles from Greenville. Enjoy your getaway at this private guest house with private drive, front & back porches, tv (streaming via Hulu Live, Disney+, Netflix, and more), washer/dryer, and full kichen including Keurig.