House vacation rentals in Pickens County
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Top-rated house rentals in Pickens County
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Pickens County house rentals
House rentals with a pool
Home in Easley
4.96 out of 5 average rating, 45 reviewsYour Carolina Oasis Awaits! *Pets FREE V(´ᴥ`)V
Jan 20 – 27
Home in Six Mile
4.81 out of 5 average rating, 16 reviewsClemson Getaway~Lake Keowee Dock
Aug 9 – 16
Home in Salem
4.75 out of 5 average rating, 8 reviewsKeowee Key - Lake, deck, firetable & Clemson!
Feb 9 – 16
Home in Salem
5.0 out of 5 average rating, 9 reviewsNewly Updated | Lake Keowee | Pool | Amenities
Dec 16 – 23
Home in Salem
4.9 out of 5 average rating, 10 reviewsLake Keowee Home near Clemson, boating, and hiking
Oct 1 – 8
Home in Salem
5.0 out of 5 average rating, 5 reviewsLake Keowee condo by marina&pool close to Clemson
Jul 9 – 16
Home in Salem
5.0 out of 5 average rating, 12 reviewsKeowee Lakefront, Dog Friendly, Resort Amenities
Oct 7 – 14
Home in Pickens
5.0 out of 5 average rating, 10 reviewsTable Rock Retreat - Pool Home In the Mountains
Dec 28 – Jan 4
Weekly house rentals
Home in Central
4.97 out of 5 average rating, 129 reviewsClemson Carriage House | Private Guest House
Dec 5 – 12
Home in Seneca
4.99 out of 5 average rating, 169 reviewsLakeside @ Lake Hartwell in Clemson, SC 🐟🌅🚤
Sep 12 – 19
Home in Six Mile
4.87 out of 5 average rating, 196 reviewsHouse on Lake Keowee swim beach in cove w/ Dock
Oct 16 – 23
Home in Clemson
4.84 out of 5 average rating, 130 reviewsClemson Memorabilia house Frank Howard III’s home
Jul 11 – 18
Home in Easley
4.91 out of 5 average rating, 176 reviewsSpectacular Lakefront Retreat on the Saluda
Oct 29 – Nov 5
Home in Pickens
4.96 out of 5 average rating, 83 reviewsCottage in Pickens
Aug 1 – 8
Home in Liberty
4.92 out of 5 average rating, 53 reviews12 min to Clemson | Quiet home in small town S.C.
Jun 19 – 26
Home in Pickens
5.0 out of 5 average rating, 21 reviewsTekoa at Table Rock
Apr 3 – 10
Private house rentals
Home in Clemson
4.95 out of 5 average rating, 44 reviewsClemson Family 3-bedroom Home Minutes From Campus
Jun 21 – 28
Home in Travelers Rest
5.0 out of 5 average rating, 15 reviewsThe Retreat in the Woods
Jan 23 – 30
Home in Pendleton
4.98 out of 5 average rating, 53 reviewsRaven's Ridge
Apr 22 – 29
Home in Seneca
4.92 out of 5 average rating, 72 reviewsCharming Secluded Lake House Convenient to Clemson
Jun 4 – 11
Home in Travelers Rest
5.0 out of 5 average rating, 40 reviewsModern Wooded Retreat
Jun 30 – Jul 7
Home in Easley
4.94 out of 5 average rating, 48 reviewsKing Bed Quiet Modern Farmhouse w/ HUGE yard
Jun 28 – Jul 5
Home in Six Mile
4.96 out of 5 average rating, 27 reviews3 BR House Near Clemson
Jan 3 – 10
Home in Six Mile
4.94 out of 5 average rating, 18 reviewsCozy Foothills Retreat
Nov 8 – 15
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