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House vacation rentals in Pickens County

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Top-rated house rentals in Pickens County

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Guest favorite
Home in Pickens
4.94 out of 5 average rating, 206 reviews

Mountain Views, Peaceful Waterfall 3 King Bedrooms

The peaceful sounds of a Rushing Waterfall welcome you to “Mountain Paradise”. Surrounded by 500 acres of forest and waterfalls, you have the ultimate level of privacy. --> 10 min to Table Rock State Park --> 3 min to The Rock Golf Club --> 26 min to Devils Fork State Park (Lake Jocassee) --> 20 min to Downtown Pickens Lavish is privacy w/ 3 separate KING bedrooms and 3 Full Baths! --> Fully stocked kitchen --> High speed internet --> Smart TVs + free Netflix & YouTube TV --> 4 parking spots

Guest favorite
The exterior of a charming brick house is framed by lush greenery. A stone pathway leads to the entrance, flanked by well-maintained shrubs and trees. Large windows allow natural light to fill the living spaces inside, providing a welcoming exterior view.
Home in Pickens
4.97 out of 5 average rating, 116 reviews

Welcome to Downtown Pickens

This beautiful brick home located on a spacious lot is waiting for you! Your family will be close to everything when you stay at this centrally-located place. 3 spacious bedrooms and 1.5 baths will make life a breeze. Dine or relax on the covered patio while the kids play in the gently sloping private backyard. Your stay on West Main St will be a dream with all the amenities of downtown Pickens being in walking distance. You are also only 20 minutes from all Greenville or Clemson has to offer.

Guest favorite
A circular seating area features six Adirondack chairs arranged around a stone fire pit, set on a gravel base. A pergola provides partial shade, while a grassy yard surrounds the area, creating a welcoming space for outdoor gatherings.
Home in Easley
4.98 out of 5 average rating, 114 reviews

Clemson|Easley|FirePit|HotTub|Blackstone

Welcome to Easley! Take a break and unwind at this quiet, peaceful and private, spacious three bedroom home conveniently located 14 miles from Clemson and 12 miles from downtown Greenville. Private home facing a wooded lot provides plenty of privacy. We also feature a bed/game room, with a checker and chess table. A great place to make memories! Close to the Doodle Trail and the Nalley Brown Nature Trail. And just a few miles from The Silos, a great place to hang out with family and friends!

Top guest favorite
A studio apartment is seen from a corner, featuring a kitchen with orange cabinetry and stainless steel appliances. Two armchairs and a small dining table are positioned in the living area, with a television mounted on the wall. Ample lighting and a neutral color palette are present.
Home in Pendleton
4.88 out of 5 average rating, 119 reviews

Basement apartment in Pendleton w/ sep. entrance

This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Top guest favorite
A serene bedroom features a four-poster bed draped with soft textiles, complemented by cozy fur accent pieces. Warm lighting creates a relaxing ambiance, while decorative wall frames and patterned rugs enhance the inviting atmosphere. Multiple windows allow natural light to filter in.
Home in Easley
4.99 out of 5 average rating, 121 reviews

Comfy, cozy duplex apt in old home downtown Easley

Comfortable, CLEAN, safe, serene, remodeled duplex apartment w/private entrance thru back of home - 20 mins to Gville/Clemson. Stocked for cooking. Near hiking, climbing, kayaking, diving, fishing, restaurants, breweries, pubs, theatres, museums, hospitals, live music venues, shopping, universities, and churches. Come home to comfy robes and rooms designed for relaxation. Note: Easley has a train track downtown - a few blocks away. This is important to note. Self check-in thru passcode

Guest favorite
A lush green lawn extends across the image, framed by trees and a backdrop of rolling hills. A bright blue sky dotted with fluffy white clouds adds to the serene atmosphere. The spacious landscape offers a tranquil view of the surrounding nature.
Home in Liberty
4.94 out of 5 average rating, 135 reviews

3 Bed Home Overlooking Fishing Pond on 10 Acres

This Home is a retreat in of itself! All New Accommodations offer Large eat in Kitchen, Primary Suite with Primary Bath. Stocked Fishing Pond! Peaceful and relaxing property to enjoy privately. If you are a foodie or shopper Greenville is only 15 miles away. Greenville has landed on countless "best of" lists so it's a must see! If Clemson is what you love we are twenty minutes from campus! Business class wifi too and cable TV Enjoy Great hiking at one of the close state parks too

Guest favorite
A newly constructed duplex is depicted, featuring a light grey exterior with black shutters. The entrance is framed by two elegant chairs on the porch. A spacious driveway leads to a well-maintained area, surrounded by neat landscaping and a clear blue sky.
Home in Pickens
4.96 out of 5 average rating, 152 reviews

Cottage in Pickens

Enjoy easy access to all the Upstate has to offer! This newly constructed 2 bedroom, 1 bath duplex apartment is located along the Doodle Trail bike route. Enjoy hiking trails and waterfalls at Table Rock and Caesars Head State Parks, catch a Clemson football game, or check out Falls Park and downtown Greenville, all from one convenient location! The home is across the street from a well-maintained local park and playground and within walking distance to a coffee shop and restaurants.

Top guest favorite
A charming home is presented in a serene neighborhood setting, featuring a well-maintained lawn and flowering shrubs. The exterior showcases a light-colored façade with a welcoming front porch and a spacious driveway leading to a two-car garage.
Home in Seneca
4.99 out of 5 average rating, 226 reviews

The Cozy Cottage

Beautiful, well-maintained home located in a private subdivision just minutes away from shopping, restaurants, lakes, golf courses, and Clemson University. This home has a fully equipped kitchen for dining in and a back patio for grilling out. The backyard overlooks a peaceful wooded area, providing a serene and private escape. Our home offers the perfect blend of tranquility and convenience. Perfect for getaways, football weekends, graduation, and other Clemson University events!

Top guest favorite
An aerial view showcases a serene landscape featuring a four-acre pond surrounded by lush greenery and autumn foliage. A winding driveway leads to a guest house nestled within the wooded area. Rolling hills provide a backdrop, enhancing the natural beauty of the property.
Home in Pickens
4.96 out of 5 average rating, 162 reviews

Our Slice of Heaven w/Views of Table Rock-Pickens

Our slice of heaven is located in the foothills of the Blue Ridge Mountains only 8 mins from Table Rock State Park. Our guest house is sitting on 55 wooded acres with our 4-acre pond and amazing awe-inspiring panoramic views of Pinnacle and Table Rock Mountain. Wrap yourself in the serenity of nature, with nothing more to wake you in the morning than the pleasant sounds of songbirds beckoning you to delight in the new day.

Top guest favorite
The exterior of the cabin is shown with a light brown facade and a modern metal roof. A patio area features a small table with two chairs, sheltered by a bright red umbrella. Lush greenery surrounds the property, contributing to a natural, serene setting.
Home in Slater-Marietta
4.98 out of 5 average rating, 103 reviews

Robin’s Nest- Cottage in the Woods

WE ARE NOW PROVIDING WIFI Get back to nature with the whole family at this tranquil cottage in the woods. Relax on the screen porch, grill out or roast marshmallows at the outdoor fire pit (wood provided). Explore the 7 acre wooded property scattered with mountain laurel or head down the road to the local fishing lake to drop a line (rods provided, bring your own bait & tackle). Games, puzzles, corn-hole & dvds provided.

Guest favorite
A cozy living area features a patterned area rug and a colorful loveseat, complemented by a comfortable chair. Light from a nearby lamp casts a warm glow. A small dining area with a wooden table is visible in the background, and a kitchenette is accessible beyond.
Home in Pickens
4.98 out of 5 average rating, 161 reviews

Hidden Retreat

4 private acres just off Hwy 11. HIKE - connector to the Palmetto trail and Table Rock State Park. BIKE - popular biking routes; Hwy 11, Hwy 288 and Hwy 178 + Doodle & Swamp Rabbit Trail. GOLF - 1 course 5 minutes away several others nearby. WATERFALLS - including the highest in the east. MOUNTAIN LAKES - 2 of the best, Jocassee & Keowee. HIDDEN RETREAT - close to many outdoor adventures. Up to 6 guests.

Top guest favorite
A bright and spacious kitchen features a central island with a granite countertop, surrounded by blue upholstered chairs. A dining table with wicker chairs is located nearby, and natural light fills the room through sliding glass doors leading to the outdoor area.
Home in Seneca
4.96 out of 5 average rating, 131 reviews

5 Min to Clemson | Large Driveway & Self Check-In

Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.

Popular amenities for Pickens County house rentals