
House vacation rentals in Pickens County
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Top-rated house rentals in Pickens County
Guests agree: these houses are highly rated for location, cleanliness, and more.

Modern Wooded Retreat
Come enjoy this modern, 1.6 acre retreat! Relax with the whole family in a place you'll never want to leave. Located 5 min. to downtown TR and less than 20 min to downtown Greenville! Roast marshmallows by the firepit, play yard jenga, connect 4 and cornhole in the fully fenced, dog friendly back yard. Close to the swamp rabbit trail, and centrally located to lakes, hiking, fishing and exciting nightlife. Let us host you, while you explore everything Greenville and Travelers Rest have to offer.

Basement apartment in Pendleton w/ sep. entrance
This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Comfy, cozy duplex apt in old home downtown Easley
Comfortable, CLEAN, safe, serene, remodeled duplex apartment w/private entrance thru back of home - 20 mins to Gville/Clemson. Stocked for cooking. Near hiking, climbing, kayaking, diving, fishing, restaurants, breweries, pubs, theatres, museums, hospitals, live music venues, shopping, universities, and churches. Come home to comfy robes and rooms designed for relaxation. Note: Easley has a train track downtown - a few blocks away. This is important to note. Self check-in thru passcode

3 Bed Home Overlooking Fishing Pond on 10 Acres
This Home is a retreat in of itself! All New Accommodations offer Large eat in Kitchen, Primary Suite with Primary Bath. Stocked Fishing Pond! Peaceful and relaxing property to enjoy privately. If you are a foodie or shopper Greenville is only 15 miles away. Greenville has landed on countless "best of" lists so it's a must see! If Clemson is what you love we are twenty minutes from campus! Business class wifi too and cable TV Enjoy Great hiking at one of the close state parks too

Cottage in Pickens
Enjoy easy access to all the Upstate has to offer! This newly constructed 2 bedroom, 1 bath duplex apartment is located along the Doodle Trail bike route. Enjoy hiking trails and waterfalls at Table Rock and Caesars Head State Parks, catch a Clemson football game, or check out Falls Park and downtown Greenville, all from one convenient location! The home is across the street from a well-maintained local park and playground and within walking distance to a coffee shop and restaurants.

Comfort & Convenience Close to Campus
The perfect blend of modern charm and full comfort & convenience just minutes from Clemson, The Pendleton Square and HWY access. You will be sure to have everything you need for your visit. Comfortably sized bedrooms with queen size beds. Spacious living area with cable TV & Netflix. Bright and open kitchen and dining fully equipped for all your cooking needs. Whether you're traveling alone for a little peace & quiet, with friends, or with family... we hope you enjoy your time here!

Our Slice of Heaven w/Views of Table Rock-Pickens
Our slice of heaven is located in the foothills of the Blue Ridge Mountains only 8 mins from Table Rock State Park. Our guest house is sitting on 55 wooded acres with our 4-acre pond and amazing awe-inspiring panoramic views of Pinnacle and Table Rock Mountain. Wrap yourself in the serenity of nature, with nothing more to wake you in the morning than the pleasant sounds of songbirds beckoning you to delight in the new day.

Pet-Friendly Country Home | Clemson & Greenville
Stay at a Top 1% Airbnb Home in the scenic Blue Ridge foothills! This 3BR retreat sleeps 8, is pet-friendly with a fenced yard, and perfectly located near Clemson, Greenville, & Easley. Relax in comfort with plush beds, Smart TVs, and family-friendly extras. We provide coffee, snacks, linens, 1 towel\washcloth for each guest, soaps, and detergents so you can settle in instantly. Your perfect getaway starts here!

Cozy 3 Br Family Home • 5 min to Clemson Campus
Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.

Livin' Easley-walk to downtown-close to everything
Welcome to Livin' Easley! Your family will be close to everything when you stay at this newly renovated bungalow style house. Downtown Easley shops, restaurants, bars and The Silos are within walking distance, and Greenville and Clemson are just a short drive away. If you'd rather stay in, enjoy everything the house has to offer including bumper pool, a card table, board games, horseshoe pits, and Netflix.

King Bed Quiet Modern Farmhouse w/ HUGE yard
Welcome home to quiet, suburban living. The home is nestled on a one acre lot with mature trees. This two bedroom home was fully renovated in 2021. It is an open concept home where you can socialize with others while you cook and dine. It has a kitchen that you can truly cook in with plenty of counter space and cooking implements. Enjoy the beautiful weather from the covered front porch!

The House on Oak Grove
Enjoy your time spent in this spacious and peaceful pet friendly space. Nicely appointed with everything you need for a short or long term stay. Ten easy miles to Clemson and 3 miles to SWU. Besides the open living space the house has a screened porch and accomodates 4 with 2 bedroom & 2 adjoining baths. The home includes washer & dryer, coffee bar, granite countertops, and microwave.
Popular amenities for Pickens County house rentals
House rentals with a pool

Keowee Key Luxury Condo - Stunning Views!

Lake Keowee Access-Dock-Pool-Grill-Clemson 17 Min

Hideaway at Hunting Hollow with pool-close to lake

Clemson football 15 minutes away. 2 night minimum.

Historic Pendleton SC

Golf view, lake access, 3 pools!

Clemson Family Clubhouse

Cottage close to Clemson
Weekly house rentals

Elegant 3BR Near Wed Venu | Grill+ Golf Next Door

Greenville's Lazy Lodge

Country Apple Cottage

Lakefront Mid-Century Dream Home / 3 mi to Clemson

Hodge Island Basement Cabin

Forest Getaway 5 mins to Clemson- Private Entrance

Mountain Retreat | 7 Acres | Arcades | Hot Tub

Emerald Shore
Private house rentals

Spacious Lakefront *Gem* Pet & Family Friendly

Modern home near Clemson, Keowee

Cozy 2BR Cottage | Close to Clemson & GVL

DockTales - Panoramic Views & Private Dock

Vaulted Ceilings & Accent Windows--1 mile from CU

New! 3/2 Home Pendleton, Clemson University!

The Llama Retreat Beautiful, Cozy Bungalow!

Black Bear Hideaway
Destinations to explore
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- Family-friendly rentals Pickens County
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- House rentals South Carolina
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- Blue Ridge Parkway
- Black Rock Mountain State Park
- The North Carolina Arboretum
- River Arts District
- Gorges State Park
- Tugaloo State Park
- Table Rock State Park
- Tallulah Gorge State Park
- Chimney Rock State Park
- Mountaintop Golf & Lake Club
- Ski Sapphire Valley
- Lake Lure Beach and Water Park
- Maggie Valley Club
- Jump Off Rock
- Tryon International Equestrian Center
- Old Edwards Club
- Wade Hampton Golf Club
- Biltmore Forest County Club
- Vineyards for Biltmore Winery
- Woolworth Walk
- French Broad River Park
- Victoria Valley Vineyards
- Discovery Island
- Thomas Wolfe Memorial




