Vacation rentals in North Santee River

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Top-rated vacation rentals in North Santee River

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Home in Pawleys Island
4.94 out of 5 average rating, 187 reviews

Unique New Remodel Close to Beach and Golf

Fully remodeled, the little cabin on the marsh is a 1 BR house with a loft. Inside is almost all wood. The house sits on the marsh water of the Waccamaw river. The neighborhood is a dirt road with a mix of mobile homes and houses. The neighbors are great and have lived on the street for decades. The house is surrounded by live oaks, nature and tidal marsh water in the backyard. Litchfield and Pawleys Island beaches are 5 minutes away. World class golf, restaurants, and grocery stores are near.

Top guest favorite
An elegantly decorated sitting area is presented with a detailed mural ceiling and rich purple drapes. A plush loveseat and two accent chairs surround a circular rug in the center. Windows allow natural light to fill the space, highlighting the ornate moldings.
Apartment in North Charleston
4.96 out of 5 average rating, 152 reviews

Bridgerton inspired fantasy 2 min from park circle

Live out your Bridgerton fantasy in this stunning historic space. The apartment features antique furnishings/art, a private entrance and patio with lounge and a hot tub (The hot tub is available Apr through Nov). Off street parking. A sumptuous bathroom with an oversized soaking tub and a kitchenette. There is also a 55 inch frame tv in the bedroom including WiFi. Available for photo shoots upon request rates may differ please contact host prior. Bridal pics by Olivia Allain Permit#2026-0414

Top guest favorite
The exterior of a two-story house is nestled among tall trees, showcasing a deck with steps leading to the ground. Screened-in porches on both levels provide ample outdoor space and views of the surrounding greenery.
Home in Georgetown
4.98 out of 5 average rating, 184 reviews

Black River Refuge on the Water

The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.

Top guest favorite
The living area features a light blue wall, complemented by framed artwork. A bright red loveseat and a dark brown sofa with colorful cushions provide seating. A glass coffee table rests on a textured dark rug, while a wooden cabinet and a television complete the space.
Apartment in Georgetown
4.98 out of 5 average rating, 318 reviews

Georgetown Vogue in the Heart of the City

Located on Front St in the heart of historic Georgetown, this 1 BR, 1 Bath, full kitchen, apartment is located on the second floor of a smartly designed, mixed use, Charleston-style building. Surrounded by restaurants, museums, theater, Harborwalk, and shops, this apartment accommodates 2 in a no smoking environment and offers high speed internet, and large screen TV. No pets. Guests enjoy a quiet setting together with 1 free pass per occupant to the Purr & Pour Cat Café. Free parking.

Superhost
A serene sunset casts warm hues over the water, with a houseboat moored alongside a covered dock. Silhouetted against the sky, fishing rods stand tall, and tall grasses frame the scene, enhancing the tranquility of this riverside setting.
Home in Georgetown
4.88 out of 5 average rating, 161 reviews

Maggie Jo’s paradise on the river !

Reconnect with nature at this unforgettable escape. Maggie jo is a 1970 completely restore houseboat. She has got a full size refrigerator , gas range ,microwave and toaster oven. Out on the back deck she has a gas grill. The aft berth has 2 full beds that are extremely comfortable. Galley dinette make into bed and the couch in the saloon pulls out also. While on the decks you will see eagles, dolphins , gator or fishing jumping out of the water. I also have 2 tandem kayaks for your use.

Top guest favorite
A wooden dock extends into calm waters, featuring two Adirondack chairs positioned at the end. Surrounding marsh grasses create a natural landscape, and a clear blue sky is visible above, enhancing the serene environment.
Home in Georgetown
4.95 out of 5 average rating, 76 reviews

Dolphin Point: Beautiful bungalow w/ private dock

King Beds, large outdoor space with fire pit, beautiful dock views at sunrise and sunset… names a few of our many amenities - 1,128 Sq Ft Home - Minutes from historic Georgetown/Winyah Bay and near Pawleys Island and the surrounding areas - Extensive parking, large outdoor screened in porch, outdoor swing and shower station, and updated appliances. Permit Number: 00000745 Business License: 12000211 Streaming services: Netflix, Hulu, HBO Max, Youtube TV, Disney+, ESPN+, Prime Video

Top guest favorite
Cottage in Georgetown
5 out of 5 average rating, 18 reviews

Charming Coastal Cottage in Historic Georgetown

Welcome to this unique Orange Street Cottage in the heart of Historic Georgetown, SC. The cottage dates back to 1910 and includes two-bedrooms and two-bathrooms. It is located three blocks from Front Street and the historic waterfront. Take a walk along the Harborwalk or spend the day shopping, eating fresh seafood or having a beverage in the many waterfront restaurants. The cottage has a full kitchen, cozy living room, covered outside area with tv, fire pit and a large back yard.

Top guest favorite
The entrance of the cabin features a modern black exterior with a circular welcome mat and a stylish door showcasing large glass panes. Potted white flowers add a touch of nature, while an outdoor chair invites relaxation amidst the greenery of surrounding trees.
Farm stay in Georgetown
4.99 out of 5 average rating, 71 reviews

Lo & Billy’s Place a Historic 1940s Newlywed Cabin

This romantic cabin located on our small farm just outside of town in the country offers a history all its own. Lo was Billy’s nickname for Lorene Ella. Lo & Billy got married in the 1950s and lived here. Renovated after meeting Lo and hearing her stories. We pay homage to the rich history of Georgetown and the Southerners that have called Lo & Billy’s Place home. Heavy on coziness & design. Full kitchen; good coffee; & comfy queen bed w/high end linens. The perfect escape.

Guest favorite
A rustic fireplace is framed by a charming brick structure, with flames gently flickering inside. Two soft, gray chairs are positioned nearby, complemented by a small marble side table. Decorative greenery and a vase of flowers enhance the cozy ambiance of the room.
Cabin in Georgetown
5 out of 5 average rating, 8 reviews

#2: The Cottage + Hot Tub + More

The Only Luxury Escape in the Heart of the Santee Delta’s Untouched Beauty! Escape to a private luxury cottage blending historic charm with modern comforts. This historic Cottage offers cozy elegance and sleeps up to seven with two king bedrooms, a loft with a daybed and pull-out twin, plus a private loft bedroom with full bed. Relax in your private garden retreat with a hot tub, and other amazing amenities! Plenty of parking for cars/trucks and trailers including boats!

Top guest favorite
Guest suite in McClellanville
4.96 out of 5 average rating, 152 reviews

Resort @ Kit Hall Pool & Gardens, near Charleston

Centrally located between Myrtle Beach, Mount Pleasant and Charleston SC ( closest beach 36 miles by car. A sanctuary with an amazing freshwater (not chlorine or salt but Ionized)swimming pool, between two national parks, The Francis Marion National Forest & Cape Romain Wildlife Refuge. Near waterways, hiking, cycling trails, fishing, low country dining, historical plantations and more. 2 bedrooms & a screened sleeping porch. 4 beds + library, kitchenette & 2 ba

Top guest favorite
A spacious living area is highlighted by wooden flooring and natural light. Two ceiling fans are visible, providing airflow. A white sofa sits in the foreground, while a dining table with blue chairs and a daybed are arranged in the back area, creating a welcoming environment.
Apartment in Georgetown
5 out of 5 average rating, 36 reviews

Private Pondside Guest Suite

This peaceful guest suite is a full private studio apartment connected to our home with a private entrance-perfect for families, boaters, hunters, or those traveling for work. Parking on the premises is available for boats, trailers, and similar vehicles. We also offer charging for your boat battery-just let us know in advance so we can accommodate your needs. Your private getaway awaits!

Top guest favorite
The kitchen features modern appliances situated alongside a contrasting dark countertop and light cabinets. The brick wall adds texture to the space, enhanced by natural light from the window above the sink. A coffee maker and utensils are neatly arranged for convenience.
Cottage in Hemingway
4.98 out of 5 average rating, 108 reviews

Peaceful cozy country cottage

Welcome to Black Mingo Country Cottage! This 1950's cottage has been recently renovated and newly furnished. You are sure to find this setting restoring and peaceful! The tranquil property is surrounded by Live Oak trees, Pecan trees and Camillias. The area is wonderful for bird watching and stargazing. If you need a break from the everyday, this is the place to come.

Popular amenities for North Santee River vacation rentals