
House vacation rentals in Matlacha
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Top-rated house rentals in Matlacha
Guests agree: these houses are highly rated for location, cleanliness, and more.

McGregor’s Gem• Heated Pool 3BR/2BA River District
🌴 Welcome to McGregor’s Gem—your ideal Southwest Florida retreat! Dive into relaxation in your private heated pool, spread out across three bedrooms and two baths, and enjoy the perfect blend of peaceful tree-lined neighborhood living just minutes from the charming Downtown Fort Myers River District, world-class beaches, and top local attractions.☀️ Whether you’re traveling with family, friends, or on business, this home offers all the modern comforts you need for a relaxing, stress-free stay

Cozy in the Cape, Water views & private salt pool
"Unbelievable Views" describe this homes Gulf-access setting. Bring or Rent a boat and dock it right in our backyard. Beautiful Long intersecting canal and majestic palm trees galore! Cozy in the Cape Villa is a TOTALLY REMODELED home with 2 spacious bedrooms and 2 baths. Beautiful Italian Terrazzo flooring throughout, all new appliances & furniture. Epoxy garage floor w/ping pong table. Screened lanai with NEW heated salt POOL(no child protection screen) No Parties ALLOWED. 6 people max allow

Lux Oceanfront Island Oasis Fish Kayak Paddleboard
Escape to this tropical Island Oasis perched on the Gulf. Watch dolphins from your balcony! This spacious oceanfront gem comfortably sleeps 8 - perfect for families or groups. Relax in this unique retreat, only steps from fishing, boating, kayaking, and the Old Florida charm of Matlacha's seafood, art galleries and restaurants. Enjoy stunning water views from every room, a fully equipped kitchen, two fully stocked coffee stations and modern amenities. Your ultimate waterfront getaway awaits!

3br 2bath Waterfront hot tub bikes kayaks and dock
Peaceful recently renovated home on Matlacha Island. This 3 bedroom 2 full bath home sits on a deep waterfront canal just a few feet from open water. Enjoy some of the best fishing in Florida and park your boat on the dock. This home includes kayaks, a paddle board, and bicycles to roam around to the many shops and restaurants . Off street parking for 2 vehicles, and a gravel area for small boat trailers. This home is one half of a duplex, but has private patio area with a 6 person hot tub.

Priceless Waterfront Escape in Matlacha
Discover island living at our newly-remodeled waterfront escape in Matlacha on a deep water canal. This spacious two-bedroom, one-bath home offers all the comforts: air conditioning, high-speed internet, and a fully equipped kitchen. Ideal for up to 7 guests with a queen-size pullout couch. Use the ice maker and deep freezer in garage. The dock is great for docking your boat. Play shuffleboard in the back family room. The back porch has a gas grill and seating for outdoor entertaining.

Key West Style Home w/ Hot Tub & Boat Lift
KEY WEST style stilted waterfront home in the heart of Matlacha! Visit all there is offer - walking distance to Blue Dog and Perfect Cup. Take a boat ride to Cabbage Key, Cayo Costa or Boca Grande! Upstairs and downstairs are screened in. The second floor is peaceful and tranquil overlooking the water and treetops. Home is a 2 bedroom, 2 bathroom, with additional bonus space with trundle bed. Home is perfect for boaters with double driveway, complimentary boat lift and cleaning station.

2 Kings, Pool, Gulf Canal, Game Room and Kayaks
Unwind Cape Coral welcomes you to sunny southwest Florida, close to magnificent beaches, fishing, shelling, Minnesota Twins Spring Training & much more. Come enjoy this new construction home with heated pool, Kayaks, heated and cooled game room (PlayStation 5), gulf access - salt water canal, 4k oled tv's & many more refreshing amenities. You will love this clean & bright home with lovely décor. Located in the highly sought after Pelican neighborhood of Southwest Cape Coral!

Matlacha Paradise! NEW Waterfront Home-Free Kayak
Matlacha is for LOVERS! Lovers of relaxation, fishing, art, friends, social scenes and enjoying Life in a beautiful location ON THE WATER! Matlacha had damage from Ian. Our new home - none. You can still walk to great restaurants, shops and the fishing bridge. Enjoy the water in Matlacha & the Barrier Islands. Use our 1 person kayak for fun or fishing from our 8'X22' FUN & SUN deck docked in the back canal with picnic table & loungers. Relax, sun, grill and fish.

Peaceful Oasis
Enjoy the best of the Cape Coral Yacht Club neighborhood. We offer beautifully restored Terrazzo floors along with all new cabinetry, appliances and furniture. The interior of the house has been greatly improved since Hurricane Ian. The lanai, pool and waterfront offer you serene splendor and beauty that you will not want to leave. We provide the most convenient location in Cape Coral, just one mile from the downtown restaurant district.

Surfside Elegance SW Cape Coral Luxe Vacation home
This elegant spacious 3 Bedroom + Den, 3 Bathroom house with split floor plan and large living room will truly make you feel home! High ceilings, a lot of natural light, large rooms, amazing Florida canal view, large heated pool. Fully remodeled in 2017 and feels like new. Location is amazing, close to Marina, Cape Harbour, restaurants. Excellent, beautiful and safe neighborhood. This home is perfect for your vacation!

Island Cottage in Matlacha, Amazing!
Waterfront 2BR home on Matlacha Island, offering comfort and true island charm. Features a spacious open kitchen, a king bedroom and a queen bedroom, each with a TV. Enjoy canal views, an outdoor sitting area, charcoal grill, kayaks, and covered carport parking. Just a 2-minute walk to Perfect Cup and Blue Dog restaurants. A great location for relaxing, exploring, and enjoying excellent fishing nearby.

Matlacha Waterfront Home | Gulf Access & Pool
Experience Matlacha from this stunning waterfront home with direct Gulf access, a heated private pool, a spacious dock, and a boat lift. Bright, refined, and deeply relaxing, it’s the perfect coastal escape for families and friends. Wake up to still waters, enjoy warm swims under the sun, and end each day with the kind of peaceful, unforgettable evenings that make you never want to leave.
Popular amenities for Matlacha house rentals
House rentals with a pool

Coastal Cowgirl - Heated Pool

Paradise Found! - 3/2 Pool Home

AquaLux Smart Home

Indulgence - luxury waterfront Heated pool home

90Degree SaltWater Pool NEW Luxury Spa Gulf Access

Pool, Hot Tub, Kayaks, Dock & Canal w/ Gulf Access

Manatee Haven / with Game Room/Waterfront Retreat!

Cape Coral Paradise on the Isles
Weekly house rentals

Resort Life in Heritage Palms

The Little Yellow Retreat with boat parking

Peaceful Lakeview Retreat / Screened Porch & Bikes

🌴ISLAND TIME! DOCK⚓️POOL🏊🏻♀️KAYAKS🛶Boat to Beach🏖 Pets

Villa Sunset Serenade II

Waterfront Oasis with Boat Lift & Hot Tub

Sandy Toes Villa - North Captiva - Water Views

Bountiful Bokeelia
Private house rentals

Cape Pool House: Modern 4 Bedroom Home

Heated Pool•Golf Cart•Pool•Trusted Local Hosts

Paradise Retreat

Heated Pool, GameRoom, EV Charger, Family Friendly

Florida, Cape Coral, SunShine

Game Room! Waterfront! Spacious!- Casa Del Sol

Relaxing Poolside Retreat

Sunny Days-Canal Home w/pool & spa
Quick stats about house rentals in Matlacha

Total vacation rentals
Explore 40 vacation rentals in Matlacha

Nightly prices starting at
Matlacha vacation rentals start at ﺩ.ﺇ147 per night before taxes and fees

Verified guest reviews
Over 1,180 verified reviews to help you choose

Family-friendly vacation rentals
30 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
40 of Matlacha vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Matlacha rentals

4.9 Average rating
Matlacha stays are highly rated by guests—averaging 4.9 out of 5!
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