Family-friendly vacation rentals in Matlacha

Mojito Island Cottage

Update: In September 2022 we were affected by Hurricane Ian. We had just over 5 feet of flooding in our treasured cottage. We have worked tirelessly to put everything back together. All new tile, walls, electric, lighting, furniture, and we even improved the bathroom! Spacious tropical home with water view from our back yard lanai. Boat Dock with Cleaning Fish Station, BBQ beautiful sunsets with fish jumping in our canal. New large kitchen and one block from art galleries, restaurants and bars.

Kitchen · Family · Layout

Waterfront Matlacha views! 2/2 Heated Pool Home

Experience old Florida island living at this incredible waterfront cottage home on Matlacha Island featuring massive waterfront views, a huge private heated pool, an authentic Seminole Indian Cheekee hut, and your own private boat ramp. This is not just a canal cottage it’s a full waterfront lifestyle property designed for relaxation & entertaining with unforgettable views & memories! This "turnkey-furnished" 2-bedroom, 2-bath retreat blends comfort with classic Florida Keys island character.

Family · Quiet · Cleanliness

Paradise Pool Waterfront Kayak bike fish from dock

New POOL, waterfront gulf access. Upstairs unit 2 bedrooms 1 full bath kitchen washer/dryer. Sleeps 6 all pillow top beds 1 king 1 queen and 1 queen memory foam pull out pack/ play crib. In the heart of Matlacha walking distance to town. Bring your boat and dock it in the property. Jump in the pool after a hot day, use kayaks, canoe, bikes, fishing rods. Direct TV sports package, high-speed internet. Boat Ramp less than half mile. Guest favorite air conditioning enclosed lanai with table sits

Kitchen · Indoor spaces · Hospitality

Key West Style Home w/ Hot Tub & Boat Lift

KEY WEST style stilted waterfront home in the heart of Matlacha! Visit all there is offer - walking distance to Blue Dog and Perfect Cup. Take a boat ride to Cabbage Key, Cayo Costa or Boca Grande! Upstairs and downstairs are screened in. The second floor is peaceful and tranquil overlooking the water and treetops. Home is a 2 bedroom, 2 bathroom, with additional bonus space with trundle bed. Home is perfect for boaters with double driveway, complimentary boat lift and cleaning station.

Indoor spaces · Family · Condition

Moon Shell Hideaway

Private entrance to your one bedroom plus den (with queen size sleeper/sofa) apartment attached to main house. Direct access to the Gulf of Mexico. Bedroom has a queen size bed and the den has a queen size sleeper/sofa. The den doubles as your kitchenette and sitting area with double sliding glass doors that open up to the shared pool and dock area. Gas grill and microwave for cooking (no stove). Boat to restaurants. Visit the Matlacha Art Galleries. Fish off the dock. WELCOME!

Indoor spaces · Family · Grill

Relaxing waterfront retreat with pool

This colorful island getaway combines laid-back coastal living with beautiful water views and easy access to Pine Island’s best restaurants and attractions.The main home comfortably sleeps up to 6 guests and features bright coastal décor, comfortable living spaces, and everything needed for a relaxing stay.Attached to the home is a private efficiency suite that sleeps an additional 2 guests,(for additional cost) making it perfect for larger families or couples traveling together.

Indoor spaces · Family · Parking

Canal Front Home Heated Pool Private Dock

Escape to this peaceful canal front home in Matlacha Isles, where you can relax in your private heated pool and screened lanai, fish from your private dock, and kayak through scenic waterways. Watch for dolphins and manatees, enjoy beautiful waterfront sunsets, and explore nearby restaurants, shops, and beaches. Comfortable, clean, and thoughtfully equipped, this waterfront retreat is the perfect place to relax, reconnect, and experience the laid back charm of Old Florida.

Indoor spaces · Kitchen · Comfort

​Boater’s Paradise: No-Bridge Gulf Access & Pool

⚓ Direct Gulf Access (No Bridges): Cruise to open water! 🏊‍♂️ FREE Heated Pool: Waterfront views, zero daily heating fees. 🛏️ Group Oasis: 4BR | 3BA | 7 Beds (Sleeps 13 comfortably). 🎣 Outdoor Living: Fish from your dock, BBQ & spectacular sunsets! 🐾 Pets Welcome & Fast Wi-Fi! 🚙 Massive Parking: Room for boat trailers! 📍 Location: Heart of Matlacha, minutes to Cape Coral. ⚡ Prime season dates book fast. Lock in your direct water access and reserve your dates today.

Kitchen · Indoor spaces · Checkout

Modern City Loft in Downtown River District

Welcome to Gun-Loft, a custom-designed modern sanctuary in the Downtown River District. This expansive 3500 square foot city loft is tailored for those seeking to embrace the cosmopolitan lifestyle, with the perfect blend of urban luxury and cultural richness. Whether it's a leisurely stroll to the Edison Ford Home, an exciting night out, or a culinary adventure in the restaurants nearby, Gun-Loft offers an unparalleled experience in the city's most coveted location.

Family · Indoor spaces · Sleep quality

Waterfront/ 2 king beds/ pool/ boat lift

Take it easy at this unique and tranquil getaway. This is the perfect place to vacation, relax, and/or work from home. You will enjoy watching dolphins, manatees and native birds while drinking coffee from the Lanai. Minutes from open water to beautiful beaches and incredible fishing. Newly renovated, waiting for you! Master has a king bed, second bedroom has a day bed that converts into a king size bed. Boat lift available at request.

Family · Accuracy · Hospitality

Redfish Room in Matlacha

Book now and save: mega discounted prices for your next vacation! The “Redfish Room” studio is located in a 5-unit waterfront house on open water. It offers a cozy atmosphere in an open-plan living and sleeping area with a fully equipped kitchen, as well as a private bathroom with a shower. The absolute highlight is the enclosed veranda with a beautiful water view – the perfect place to relax and unwind.

Family · Kitchen · Cleanliness

Matlacha Hideaway. Renovated in 2025. Heated pool!

Completely renovated waterfront mid-century modern home with a rare full size and salt water pool in Matlacha. This spacious and stylish home is less than a ten minute walk from the main road with restaurants and shopping. Brand new landscaping, patio, dock and boat lift to help make your time on island memorable.

Indoor spaces · Kitchen · View